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AGM11504.1

Arc-Vir

KC292026__AGM11504.1__HGTV1-207__00174

Identity

Accession:
KC292026 ↗
Protein ID:
AGM11504.1 ↗
Kingdom:
archaea

Quality

91.7 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Thumleimavirales› Halomagnusviridae› Hagravirus› Halogranum_tailed_virus_1

TaxID: 1273749

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-48
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vb6A01 2.30.30.360 Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal 0.74 57.0 5.32e-01 95.2% 66.7%
4z88A00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.71 53.0 4.70e-01 100.0% 53.8%
4q66D01 6.20.120.50 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.70 53.0 4.48e-01 97.6% 47.9%
1jegA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.68 51.0 4.65e-01 100.0% 60.0%
7z0kB01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.68 53.0 4.75e-01 100.0% 60.9%
2wfwB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 55.0 4.84e-01 100.0% 91.0%
4mi7A00 3.90.70.170 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.64 55.0 3.98e-01 100.0% 42.7%
3bdlA01 2.40.50.90 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.63 50.0 3.49e-01 97.6% 63.9%
5yrzB00 3.30.920.30 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Hypothetical protein. 0.63 47.0 4.33e-01 85.7% 65.5%
2l5qA01 2.30.30.730 Mainly Beta › Roll › SH3 type barrels. › 0.63 49.0 4.70e-01 100.0% 76.0%
3i1aA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 48.0 3.69e-01 88.1% 83.5%
4gymB00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.62 45.0 3.17e-01 81.0% 67.4%
1dkiC01 3.90.70.50 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Streptopain (SpeB) 0.61 50.0 3.34e-01 97.6% 60.3%
5j60B02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.61 49.0 3.62e-01 100.0% 32.5%
2mfiA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 51.0 4.02e-01 100.0% 43.8%
2rbbA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.61 43.0 3.17e-01 78.6% 25.6%
1e5bA00 2.60.40.290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 45.0 3.64e-01 85.7% 85.1%
2kcjA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.59 47.0 3.67e-01 100.0% 63.0%
2m3xC02 2.40.10.360 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.59 41.0 3.59e-01 81.0% 46.4%
2da0A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 44.0 3.52e-01 100.0% 56.1%
4py5A01 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.58 42.0 3.57e-01 78.6% 43.1%
1et9A02 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.58 47.0 3.89e-01 95.2% 74.7%
5tkwA02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.58 42.0 3.80e-01 85.7% 81.8%
4nswA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 45.0 3.59e-01 100.0% 61.5%
2d9xA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 45.0 3.55e-01 100.0% 60.9%
3lzhA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 41.0 3.33e-01 81.0% 47.3%
3pmiA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.57 46.0 4.17e-01 100.0% 70.8%
1w97L02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.57 42.0 3.67e-01 88.1% 86.7%
2wmmA02 3.30.70.3500 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › MukB, hinge domain 0.57 43.0 3.27e-01 88.1% 64.6%
4c5wA01 3.30.2020.30 Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › 0.56 45.0 3.56e-01 95.2% 66.0%
4phtY02 3.30.420.370 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › GspL cytoplasmic domain, C-terminal subdomain 0.56 42.0 3.82e-01 88.1% 80.6%
3e1tA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 46.0 2.91e-01 100.0% 16.5%
4z3xA03 1.10.569.10 Mainly Alpha › Orthogonal Bundle › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A; domain 2 › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2 0.55 42.0 2.84e-01 88.1% 28.5%
2khjA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 43.0 3.62e-01 100.0% 49.4%
1faoA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.55 42.0 3.46e-01 100.0% 69.0%
1d0cA02 3.90.440.10 Alpha Beta › Alpha-Beta Complex › Nitric Oxide Synthase;Heme Domain; Chain A, domain 2 › Nitric Oxide Synthase;Heme Domain;Chain A domain 2 0.54 40.0 3.19e-01 88.1% 93.2%
2ogqA01 3.30.1120.30 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › POLO box domain 0.54 44.0 3.28e-01 100.0% 70.6%
3vm7A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.53 36.0 2.79e-01 71.4% 27.6%
3havA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 38.0 3.19e-01 88.1% 79.8%
1alyA00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.51 38.0 2.73e-01 88.1% 95.2%
1b0yA00 4.10.490.10 Few Secondary Structures › Irregular › High-Potential Iron-Sulfur Protein; Chain A › High potential iron-sulphur protein 0.51 41.0 3.42e-01 100.0% 81.2%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3956735 6055.1.1.1 ↗ extended segments › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › YajC 0.81 60.0 5.90e-01 100.0% 75.6%
3989139 4.1.1.297 ↗ beta barrels › SH3 › SH3 › SH3 › YajC 0.79 60.0 5.23e-01 97.6% 53.8%
4347999 4.1.1.297 ↗ beta barrels › SH3 › SH3 › SH3 › YajC 0.79 61.0 5.23e-01 100.0% 53.8%
3278801 4.1.1.297 ↗ beta barrels › SH3 › SH3 › SH3 › YajC 0.78 59.0 5.16e-01 100.0% 53.8%
3992514 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.70 55.0 5.59e-01 97.6% 92.5%
3210377 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.70 48.0 3.01e-01 78.6% 12.9%
4214438 4.1.1.97 ↗ beta barrels › SH3 › SH3 › SH3 › DUF150_C 0.69 51.0 4.59e-01 100.0% 55.4%
3725260 4.1.1.1 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_1 0.69 52.0 4.51e-01 100.0% 51.4%
4679625 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.67 58.0 5.19e-01 100.0% 73.3%
3770704 2.1.1.49 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › MRP-S35 0.66 55.0 4.92e-01 97.6% 66.7%
4958385 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.66 51.0 5.18e-01 95.2% 92.5%
3929699 5.1.4.244 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_ELP1_2nd 0.65 45.0 2.79e-01 76.2% 11.7%
4371107 2.1.1.11 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-1a 0.65 56.0 4.23e-01 100.0% 66.7%
4325664 330.7.1.0 ↗ a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain 0.65 52.0 4.69e-01 90.5% 68.3%
4932594 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.65 55.0 4.34e-01 97.6% 61.1%
4980752 2.1.1.11 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-1a 0.65 56.0 4.22e-01 100.0% 65.7%
3626865 2.1.1.49 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › MRP-S35 0.64 54.0 3.86e-01 97.6% 58.5%
3767452 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.64 52.0 4.01e-01 100.0% 77.3%
4369338 2.1.1.21 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Methyltrn_RNA_3 0.63 52.0 4.48e-01 95.2% 84.3%
4384294 2.1.1.60 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RsgI_N 0.63 50.0 5.07e-01 92.9% 92.5%
5000308 4.1.1.3 ↗ beta barrels › SH3 › SH3 › SH3 › KOW 0.63 50.0 4.91e-01 100.0% 83.7%
4024623 2.1.1.11 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-1a 0.63 53.0 4.41e-01 100.0% 83.7%
3399018 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.63 47.0 3.10e-01 90.5% 59.6%
3851686 2.1.1.49 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › MRP-S35 0.62 53.0 4.21e-01 100.0% 82.2%
4659440 2.4.1.1 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE 0.62 52.0 3.65e-01 95.2% 93.3%
3304191 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.61 49.0 3.38e-01 100.0% 57.1%
2573569 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 51.0 3.19e-01 100.0% 22.8%
3244959 2.1.1.7 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › S1 0.61 50.0 4.38e-01 100.0% 92.9%
4543309 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.61 47.0 3.67e-01 100.0% 59.1%
4399684 7502.1.1.1 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HGTP_anticodon 0.60 48.0 3.70e-01 92.9% 91.4%
3617551 2.1.1.7 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › S1 0.60 50.0 4.44e-01 100.0% 69.2%
146634 4.1.1.119 ↗ beta barrels › SH3 › SH3 › SH3 › DUF5606 0.60 49.0 4.73e-01 100.0% 83.7%
4029417 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.60 44.0 2.70e-01 85.7% 26.7%
3419950 220.1.1.113 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_11 0.59 47.0 3.48e-01 100.0% 72.6%
3368603 330.7.1.0 ↗ a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain 0.59 41.0 4.11e-01 78.6% 91.1%
4011957 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.59 48.0 3.70e-01 100.0% 50.4%
3260650 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.58 46.0 3.59e-01 100.0% 60.9%
3891023 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.58 45.0 3.15e-01 100.0% 36.7%
3347387 220.1.1.113 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_11 0.58 44.0 3.23e-01 100.0% 76.1%
4920636 2.1.1.70 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_C 0.58 44.0 3.86e-01 95.2% 74.0%
5035582 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.58 48.0 3.62e-01 100.0% 55.7%
4312876 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.58 47.0 3.42e-01 95.2% 49.2%
3628042 243.4.1.0 ↗ a+b two layers › Cystatin-like › DsbC/DsbG N-terminal domain-like › DsbC/DsbG N-terminal domain-like 0.57 41.0 3.89e-01 81.0% 70.9%
5038045 2486.1.1.1 ↗ a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 0.57 41.0 2.49e-01 81.0% 20.3%
3456358 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 42.0 3.39e-01 88.1% 47.0%
4348945 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.57 44.0 3.43e-01 100.0% 55.0%
3242245 719.1.1.0 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain 0.57 41.0 3.70e-01 83.3% 80.0%
3256843 220.1.1.8 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.57 44.0 3.56e-01 100.0% 61.0%
3590354 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.57 47.0 3.44e-01 100.0% 52.6%
4004773 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.56 45.0 3.40e-01 100.0% 49.6%
5052502 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.56 46.0 3.34e-01 100.0% 48.1%
3955839 2.4.1.3 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2,OB_MalK 0.55 44.0 3.24e-01 100.0% 36.9%
3399883 4161.1.1.0 ↗ beta complex topology › MOSC N-terminal domain-like › MOSC N-terminal domain-like › MOSC N-terminal domain-like 0.54 39.0 2.48e-01 83.3% 24.6%
5039029 220.1.1.76 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 0.54 40.0 3.42e-01 97.6% 75.6%
3501302 318.1.1.1 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.54 38.0 2.94e-01 83.3% 50.8%
4956223 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.53 41.0 2.56e-01 95.2% 86.8%
4950893 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.52 41.0 3.62e-01 92.9% 95.7%
3237575 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.52 38.0 2.43e-01 90.5% 16.1%
4130134 3468.1.1.1 ↗ a+b two layers › HLTF protein HIRAN domain › HLTF protein HIRAN domain › HLTF protein HIRAN domain › HIRAN 0.51 40.0 2.96e-01 100.0% 50.7%
D2 high residues 56-111
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fk5A02 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.72 54.0 3.30e-01 80.4% 15.3%
4hdoA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.71 50.0 4.27e-01 75.0% 48.9%
2hzmA02 2.20.140.20 Mainly Beta › Single Sheet › q64v53_bacfr protein fold › 0.71 57.0 4.94e-01 87.5% 88.2%
4msxA02 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.69 52.0 3.24e-01 82.1% 15.9%
1y9lA00 2.40.128.230 Mainly Beta › Beta Barrel › Lipocalin › Pilot protein MxiM 0.68 51.0 4.11e-01 82.1% 93.6%
3au4A04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.68 47.0 4.05e-01 75.0% 46.2%
7w3rB01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.67 52.0 3.25e-01 85.7% 24.8%
5chtB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.67 53.0 3.33e-01 87.5% 18.7%
3hkoA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 53.0 3.53e-01 89.3% 41.2%
4iapA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.66 46.0 4.01e-01 76.8% 48.9%
3hrsA02 2.30.30.90 Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) 0.65 49.0 4.46e-01 82.1% 86.8%
2fn0B00 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.65 45.0 2.71e-01 82.1% 10.0%
6o5cA02 2.30.30.90 Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) 0.65 48.0 4.41e-01 82.1% 86.8%
3ifvC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.64 49.0 3.11e-01 80.4% 94.2%
5dcmB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 55.0 4.63e-01 100.0% 79.6%
2de6A02 2.20.25.680 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.63 45.0 4.46e-01 100.0% 72.4%
3ihpA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.62 44.0 3.48e-01 75.0% 62.1%
4chjA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.62 49.0 3.88e-01 89.3% 58.9%
6grrB01 3.30.457.10 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Copper amine oxidase-like, N-terminal domain 0.62 52.0 4.75e-01 98.2% 92.4%
1hdhA02 3.30.1120.10 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.60 44.0 4.01e-01 78.6% 66.2%
3bs1A00 2.40.50.1020 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › LytTr DNA-binding domain 0.60 42.0 3.47e-01 78.6% 39.8%
3e19B01 2.30.30.90 Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) 0.60 43.0 4.20e-01 78.6% 98.4%
2jwkA00 3.30.420.270 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.60 42.0 3.89e-01 75.0% 97.3%
1xteA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.60 48.0 3.93e-01 92.9% 97.4%
4q1vA01 2.140.10.30 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Dipeptidylpeptidase IV, N-terminal domain 0.59 49.0 2.90e-01 92.9% 17.0%
1wquA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.59 52.0 4.15e-01 100.0% 69.3%
2bs6A01 2.40.128.190 Mainly Beta › Beta Barrel › Lipocalin › 0.59 48.0 4.26e-01 92.9% 85.7%
3u1wA01 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 49.0 3.50e-01 98.2% 48.6%
1ywyA00 3.40.1170.40 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › Protein of unknown function DUF3203 0.58 43.0 4.00e-01 82.1% 64.9%
6rwcA02 2.20.25.590 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.58 33.0 3.79e-01 94.6% 79.5%
1sg5A01 2.30.30.400 Mainly Beta › Roll › SH3 type barrels. › Rof-like 0.58 42.0 3.83e-01 78.6% 77.9%
3gxwC00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.57 45.0 3.82e-01 89.3% 89.0%
4cvuA05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 44.0 3.77e-01 83.9% 84.3%
6e55A01 2.30.30.90 Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) 0.57 41.0 3.80e-01 78.6% 90.5%
2gfoA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.57 41.0 2.61e-01 80.4% 89.4%
3x3nA04 2.40.50.910 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Type VII secretion system EccB, repeat 3 domain 0.57 47.0 4.09e-01 94.6% 87.6%
1ov3A02 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.56 40.0 4.05e-01 76.8% 100.0%
4g3wA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.56 43.0 3.42e-01 91.1% 47.4%
7d27A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.56 46.0 3.18e-01 98.2% 38.7%
4bdxA00 2.10.25.10 Mainly Beta › Ribbon › Laminin › Laminin 0.55 39.0 3.51e-01 75.0% 83.1%
6my0A02 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.55 39.0 3.83e-01 78.6% 86.2%
5cvmA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.55 41.0 2.66e-01 87.5% 90.6%
4cbvA02 2.40.50.1020 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › LytTr DNA-binding domain 0.55 42.0 3.32e-01 83.9% 45.8%
3gceA00 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.54 46.0 3.87e-01 100.0% 60.6%
4dguA02 2.60.40.2670 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 48.0 3.84e-01 96.4% 95.2%
5vmzA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.54 33.0 3.55e-01 92.9% 82.1%
6uy8A01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.54 38.0 3.83e-01 78.6% 98.3%
1gcqB00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.53 38.0 3.84e-01 78.6% 98.2%
5o99A00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.52 38.0 3.74e-01 80.4% 95.0%
1bxgA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.51 41.0 3.30e-01 98.2% 46.7%
2qmlA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 36.0 2.63e-01 82.1% 95.3%
6uzjA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.50 36.0 3.51e-01 78.6% 95.2%
1jbjA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 39.0 3.62e-01 87.5% 94.7%
2dmoA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.50 35.0 3.43e-01 78.6% 86.8%
5llwA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.50 36.0 3.25e-01 82.1% 98.9%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.50 35.0 3.02e-01 75.0% 48.9%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3412093 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.72 55.0 3.33e-01 82.1% 85.2%
3566967 220.1.1.170 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_alsin 0.72 52.0 4.21e-01 76.8% 45.7%
3627795 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.72 52.0 4.57e-01 78.6% 54.1%
3743864 109.4.1.1787 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nup188_N-subdom_III 0.71 60.0 3.22e-01 94.6% 5.1%
3840270 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.71 52.0 4.05e-01 78.6% 38.3%
3510148 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.71 51.0 3.88e-01 76.8% 34.6%
3660442 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.70 54.0 3.29e-01 82.1% 15.2%
3874132 220.1.1.170 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_alsin 0.70 50.0 4.00e-01 76.8% 41.7%
3271978 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.70 52.0 3.18e-01 80.4% 15.0%
3244890 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.70 51.0 3.99e-01 78.6% 40.8%
3920985 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.70 53.0 3.18e-01 82.1% 14.0%
3246511 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.69 51.0 3.15e-01 80.4% 14.8%
3626345 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.68 49.0 3.97e-01 76.8% 43.6%
3224950 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.68 50.0 4.11e-01 80.4% 45.7%
3166921 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.68 51.0 3.15e-01 82.1% 18.0%
4996608 2007.9.1.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.68 50.0 3.43e-01 80.4% 37.0%
3275677 220.1.1.66 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.68 48.0 3.51e-01 76.8% 28.7%
3273591 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.68 49.0 3.77e-01 78.6% 36.9%
3940305 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.67 50.0 3.34e-01 80.4% 22.3%
3809821 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.67 51.0 3.10e-01 91.1% 13.4%
3756160 220.1.1.33 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_8 0.67 48.0 3.65e-01 78.6% 33.8%
3923930 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.67 48.0 3.93e-01 78.6% 44.5%
3792816 220.1.1.33 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_8 0.67 48.0 3.84e-01 78.6% 40.8%
3515019 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.66 50.0 3.18e-01 83.9% 17.4%
3814705 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.65 50.0 3.05e-01 83.9% 89.1%
3274553 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.65 48.0 3.97e-01 80.4% 45.7%
3912099 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.64 47.0 3.89e-01 80.4% 44.8%
3577264 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.64 45.0 3.39e-01 76.8% 31.3%
2082647 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.63 55.0 3.58e-01 98.2% 90.7%
3177989 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.63 50.0 2.94e-01 87.5% 87.3%
3936608 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.63 47.0 3.81e-01 80.4% 40.9%
4040812 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.63 52.0 4.49e-01 92.9% 85.4%
4449615 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.63 51.0 4.39e-01 91.1% 84.4%
3706282 376.1.3.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.62 52.0 4.20e-01 100.0% 46.7%
4379527 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.62 50.0 4.40e-01 91.1% 89.4%
4174140 318.1.1.0 ↗ a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.62 53.0 4.72e-01 96.4% 91.3%
3415741 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.61 49.0 3.59e-01 92.9% 33.8%
4975819 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.61 44.0 2.97e-01 78.6% 80.9%
3947154 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.61 51.0 4.39e-01 94.6% 85.6%
4945288 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.61 43.0 4.67e-01 76.8% 100.0%
5078978 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.60 52.0 3.35e-01 96.4% 33.2%
3416458 386.1.1.259 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF29169 0.60 38.0 4.08e-01 94.6% 77.8%
3167802 220.1.1.33 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_8 0.60 48.0 3.91e-01 89.3% 66.7%
3218510 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.59 46.0 3.92e-01 89.3% 52.0%
3028388 319.1.1.4 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › ArsA_HSP20 0.59 47.0 4.33e-01 87.5% 68.1%
4122616 4337.1.1.0 ↗ a+b two layers › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain 0.59 46.0 4.03e-01 92.9% 85.3%
3518421 2002.1.1.30 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.58 41.0 2.51e-01 73.2% 17.8%
3949260 4120.1.1.0 ↗ few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP 0.58 42.0 3.41e-01 78.6% 91.8%
4956688 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.58 50.0 3.78e-01 98.2% 85.0%
4936291 4.1.1.487 ↗ beta barrels › SH3 › SH3 › SH3 › DUF7205 0.58 44.0 4.24e-01 85.7% 87.7%
3715600 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 48.0 2.88e-01 100.0% 45.0%
2077327 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.57 46.0 4.02e-01 94.6% 79.8%
5068028 316.1.1.2 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.57 41.0 2.78e-01 76.8% 21.8%
4527507 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.57 46.0 3.73e-01 100.0% 89.2%
3779549 4337.1.1.1 ↗ a+b two layers › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › MutL_C 0.57 46.0 3.73e-01 92.9% 60.2%
5047010 2008.1.1.63 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › MvaI_BcnI 0.55 44.0 3.07e-01 98.2% 48.4%
4406214 101.1.2.70 ↗ alpha arrays › HTH › HTH › winged helix domain › PqqD 0.55 43.0 3.74e-01 91.1% 81.7%
3414114 2002.1.1.30 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.55 41.0 2.48e-01 80.4% 16.7%
3404585 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.54 34.0 3.52e-01 94.6% 70.0%
3214156 2002.1.1.30 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.54 39.0 2.45e-01 80.4% 21.4%
3550232 389.1.1.1 ↗ few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › EGF 0.54 34.0 3.02e-01 98.2% 43.5%
3396514 386.1.1.259 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF29169 0.54 35.0 3.74e-01 94.6% 84.4%
4958164 298.1.1.42 ↗ a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA 0.52 37.0 2.35e-01 76.8% 92.8%
3595091 109.1.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.52 37.0 2.63e-01 78.6% 94.7%
3361094 284.2.1.1 ↗ a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain › Glyco_hydro_18 0.51 42.0 2.51e-01 87.5% 15.8%
3696553 2004.5.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain 0.50 43.0 3.02e-01 92.9% 72.5%
D3 medium residues 118-244
PDB
Domain cluster: rep: KC292026__AGM11464.1__HGTV1-167__00134__D126-250
D4 medium residues 259-337
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2q37A00 1.10.3330.10 Mainly Alpha › Orthogonal Bundle › UraD-like › Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase 0.60 47.0 3.89e-01 84.8% 97.9%
1jeyA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.59 47.0 3.51e-01 88.6% 97.6%
2qkdA04 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.56 43.0 3.69e-01 82.3% 67.7%
4l7nA01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.52 41.0 3.45e-01 87.3% 72.0%
7oq4Z01 1.20.120.950 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 0.51 37.0 3.55e-01 79.7% 65.3%
2roqA01 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.51 37.0 3.51e-01 78.5% 69.1%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3207001 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.58 44.0 3.72e-01 83.5% 77.9%
3714005 5054.1.1.61 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.53 41.0 2.88e-01 82.3% 55.7%
4030382 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.51 43.0 3.32e-01 98.7% 79.5%
3654557 609.1.1.1 ↗ alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg 0.51 39.0 3.43e-01 86.1% 74.6%
3899637 150.3.1.2 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Interferon 0.50 42.0 3.54e-01 100.0% 70.6%