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KM083128.1__AII28201.1__PBI_SPARKY_57__00053

Bact-Vir

KM083128.1__AII28201.1__PBI_SPARKY_57__00053

Identity

Accession:
KM083128 ↗
Kingdom:
phage

Quality

76.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 196-256
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3b7hA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.76 56.0 5.28e-01 80.3% 80.3%
3f51C00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.74 55.0 4.85e-01 80.3% 66.7%
3bs3A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.74 52.0 5.25e-01 73.8% 88.3%
2ef8A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.73 58.0 5.25e-01 88.5% 76.2%
3ilkA02 1.10.8.590 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.73 59.0 5.73e-01 86.9% 88.2%
3bbzA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.71 53.0 5.83e-01 78.7% 100.0%
4pu7A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.71 53.0 5.12e-01 82.0% 83.1%
4ghjB00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.70 52.0 4.94e-01 82.0% 77.6%
4heoA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.70 56.0 5.91e-01 86.9% 96.4%
1b0nA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.70 51.0 4.32e-01 78.7% 78.6%
1r69A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.70 48.0 4.82e-01 73.8% 85.7%
1y7yA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.69 52.0 5.02e-01 82.0% 89.9%
2mqkA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.69 51.0 5.09e-01 82.0% 96.9%
2bnmA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.69 51.0 4.85e-01 82.0% 82.4%
7vjmB01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.69 51.0 5.04e-01 80.3% 96.9%
6qpqB00 1.10.10.580 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E 0.68 47.0 4.32e-01 72.1% 79.0%
3fymA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.68 50.0 4.58e-01 80.3% 75.6%
2ewtA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.68 50.0 4.84e-01 82.0% 88.7%
1x57A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.66 50.0 4.43e-01 83.6% 78.0%
4ybaA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.66 50.0 4.71e-01 85.2% 79.2%
4yg1A00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.66 48.0 4.63e-01 80.3% 83.3%
2auwB02 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.65 56.0 5.44e-01 100.0% 90.0%
2ictA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.65 48.0 4.47e-01 82.0% 74.1%
2r1jL00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.64 47.0 4.60e-01 80.3% 86.4%
6rnzA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.63 46.0 4.52e-01 80.3% 86.4%
2o38A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.62 43.0 4.32e-01 75.4% 95.4%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.62 50.0 4.03e-01 90.2% 63.2%
1ls1A01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.61 49.0 4.39e-01 91.8% 89.9%
1ztdA00 1.10.1520.20 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III 0.61 47.0 3.83e-01 88.5% 54.4%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.60 49.0 3.72e-01 88.5% 40.3%
6sdkA01 1.10.10.2830 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 42.0 3.73e-01 100.0% 48.5%
2a6cA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.60 42.0 3.99e-01 77.0% 81.6%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.59 48.0 4.41e-01 91.8% 71.6%
1tj7A03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.59 41.0 3.94e-01 73.8% 67.6%
6pw7A02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.58 40.0 3.88e-01 73.8% 100.0%
4q1tB01 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.58 41.0 2.71e-01 73.8% 90.8%
4hhxA00 1.20.81.30 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › Type II secretion system (T2SS), domain F 0.56 39.0 3.25e-01 72.1% 63.5%
1z6tA03 1.10.8.430 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Helical domain of apoptotic protease-activating factors 0.55 44.0 4.09e-01 95.1% 69.1%
2xseA00 1.20.120.1440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain 0.54 43.0 3.21e-01 85.2% 94.3%
4qozC00 1.10.8.1120 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Histone RNA hairpin-binding protein RNA-binding domain 0.54 44.0 4.20e-01 93.4% 87.7%
6xssA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 41.0 3.93e-01 85.2% 73.9%
2yqzA02 1.10.8.900 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 40.0 3.85e-01 83.6% 77.9%
5i1uA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 43.0 2.79e-01 95.1% 93.0%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 38.0 3.11e-01 82.0% 70.5%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4147763 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.74 55.0 5.31e-01 80.3% 84.3%
4997208 2004.1.1.146 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.73 58.0 3.71e-01 86.9% 20.3%
320075 632.6.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Epsilon_antitox 0.73 62.0 5.25e-01 90.2% 83.2%
4928770 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.71 52.0 5.59e-01 78.7% 98.0%
4960529 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.70 54.0 5.66e-01 90.2% 94.5%
4956880 101.1.4.3 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 0.69 51.0 4.93e-01 80.3% 81.4%
3965368 101.1.4.20 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_37 0.69 52.0 4.79e-01 82.0% 78.8%
4818340 101.1.1.9 alpha arrays › HTH › HTH › Three-helical HTH › HTH_3 0.69 50.0 5.00e-01 78.7% 93.7%
4940450 101.1.4.18 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_31 0.69 50.0 4.73e-01 78.7% 78.7%
1563574 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.69 51.0 5.09e-01 82.0% 96.9%
5030212 101.1.4.3 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 0.69 49.0 4.79e-01 78.7% 84.3%
4448496 101.1.4.27 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › CYNS_N 0.67 48.0 4.69e-01 78.7% 82.9%
5028787 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.66 48.0 4.60e-01 80.3% 80.0%
4962469 101.1.2.925 alpha arrays › HTH › HTH › winged helix domain › DUF7344 0.66 43.0 3.18e-01 77.0% 25.6%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.65 47.0 3.69e-01 78.7% 67.9%
3999292 101.1.4.27 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › CYNS_N 0.65 48.0 4.33e-01 80.3% 69.4%
3888291 11.2.1.19 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF3657 0.65 52.0 3.41e-01 90.2% 90.4%
3943356 101.1.4.19 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_35 0.64 47.0 4.50e-01 82.0% 74.7%
3241469 130.1.1.1 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.63 40.0 4.18e-01 88.5% 70.9%
5083369 604.4.1.0 alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP 0.62 40.0 3.49e-01 75.4% 43.0%
5021128 873.1.1.12 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › PF27313 0.60 41.0 3.26e-01 70.5% 36.8%
3583564 130.1.1.1 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.60 37.0 3.59e-01 82.0% 52.9%
3998880 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 43.0 3.78e-01 78.7% 87.4%
5072615 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.59 41.0 3.47e-01 90.2% 40.9%
2791 101.1.4.20 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_37 0.59 46.0 4.09e-01 86.9% 74.2%
4414334 101.1.4.27 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › CYNS_N 0.59 44.0 4.06e-01 82.0% 76.2%
4962468 101.1.2.925 alpha arrays › HTH › HTH › winged helix domain › DUF7344 0.58 45.0 3.75e-01 83.6% 65.7%
3689931 130.1.1.0 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.57 40.0 3.96e-01 75.4% 67.7%
3623379 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.56 42.0 3.64e-01 80.3% 88.4%
4964800 101.1.2.925 alpha arrays › HTH › HTH › winged helix domain › DUF7344 0.56 43.0 3.60e-01 83.6% 65.7%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.56 50.0 3.77e-01 100.0% 60.1%
3352218 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.53 41.0 3.82e-01 85.2% 76.2%
D2 high residues 379-467
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gf4A00 1.20.1270.110 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Uncharacterised protein family UPF0058 0.70 50.0 5.03e-01 78.7% 73.9%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.63 49.0 4.22e-01 87.6% 53.2%
3d2eA06 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 47.0 4.32e-01 78.7% 65.5%
1nv8B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.62 46.0 5.04e-01 89.9% 100.0%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.61 42.0 4.69e-01 86.5% 95.5%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.60 45.0 4.81e-01 77.5% 90.8%
2igsA00 1.10.3690.10 Mainly Alpha › Orthogonal Bundle › PA2222-like fold › PA2222-like domain 0.58 50.0 3.88e-01 98.9% 99.5%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.57 45.0 3.57e-01 87.6% 46.4%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.56 43.0 3.31e-01 80.9% 80.2%
1nu7D02 1.20.120.760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle, domain 2 0.56 42.0 3.77e-01 79.8% 58.6%
2uxwA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 41.0 3.27e-01 78.7% 52.2%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 37.0 3.29e-01 78.7% 47.3%
2b5dX02 1.20.1430.10 Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain 0.54 46.0 4.22e-01 92.1% 92.1%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 40.0 2.95e-01 83.1% 76.8%
4n6cB00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.53 46.0 3.60e-01 94.4% 69.1%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.53 40.0 3.60e-01 78.7% 83.2%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 41.0 3.52e-01 87.6% 88.5%
3w0fA02 1.10.8.50 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 45.0 3.95e-01 96.6% 75.0%
1tdzA02 1.10.8.50 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 45.0 3.97e-01 97.8% 82.1%
3byiD00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.51 37.0 2.84e-01 88.8% 32.1%
3hriB01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.51 40.0 2.86e-01 88.8% 57.9%
2gfhA02 1.20.120.710 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain 0.51 35.0 3.55e-01 89.9% 73.3%
1cy5A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 37.0 3.68e-01 77.5% 89.1%
1k3xA02 1.10.8.50 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 43.0 3.91e-01 97.8% 75.6%
6wfqC01 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.51 36.0 3.15e-01 78.7% 47.2%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.50 44.0 2.91e-01 100.0% 88.9%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3731997 3831.1.1.0 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.68 51.0 4.56e-01 78.7% 90.4%
3819438 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.66 34.0 3.27e-01 98.9% 41.0%
3425929 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.65 39.0 3.50e-01 91.0% 43.3%
3179691 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 49.0 3.62e-01 88.8% 50.8%
5012015 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 48.0 3.88e-01 87.6% 50.3%
3395171 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.59 48.0 3.68e-01 87.6% 42.0%
5024245 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.59 29.0 2.71e-01 86.5% 36.4%
3288375 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.59 48.0 3.73e-01 88.8% 45.6%
4541653 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.59 33.0 3.27e-01 70.8% 52.6%
4956384 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.59 48.0 3.68e-01 87.6% 87.2%
4974387 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.59 51.0 3.43e-01 97.8% 62.5%
3703167 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.59 48.0 3.62e-01 88.8% 95.3%
4077250 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 47.0 3.46e-01 87.6% 35.7%
3759592 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 46.0 3.45e-01 85.4% 38.2%
3576020 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 47.0 3.64e-01 88.8% 48.0%
4949390 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 46.0 3.72e-01 88.8% 49.7%
3546057 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 45.0 3.40e-01 87.6% 37.0%
5079323 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 45.0 3.67e-01 88.8% 51.1%
3727838 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.56 45.0 3.40e-01 88.8% 50.2%
3508870 148.1.3.172 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_14 0.56 41.0 3.96e-01 88.8% 69.0%
4009602 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.56 44.0 3.27e-01 87.6% 37.6%
5079159 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 46.0 3.51e-01 89.9% 82.5%
3220780 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 44.0 3.33e-01 88.8% 43.9%
3993135 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 40.0 3.09e-01 78.7% 75.9%
3690688 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 42.0 3.39e-01 88.8% 50.3%
4979114 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.53 40.0 3.60e-01 80.9% 83.2%
1700024 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.52 41.0 3.31e-01 87.6% 55.6%
3480000 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.51 43.0 3.10e-01 96.6% 60.0%
D3 medium residues 36-100_155-195
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3is5F02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 45.0 3.85e-01 91.5% 89.1%
2qyuA04 1.10.4140.10 Mainly Alpha › Orthogonal Bundle › effector protein (NleL) fold › effector protein (NleL) 0.54 42.0 3.39e-01 81.1% 60.1%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 30.0 3.46e-01 85.8% 81.3%
4xvxA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 34.0 3.40e-01 80.2% 64.9%
4c0tA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 41.0 3.44e-01 90.6% 84.7%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4929015 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 36.0 4.17e-01 82.1% 100.0%
3441766 109.4.1.1559 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tic110 0.51 36.0 2.68e-01 97.2% 27.3%
D4 medium residues 101-154
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3khpD01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.78 53.0 3.88e-01 70.4% 29.4%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.77 51.0 4.35e-01 74.1% 43.0%
1c8uA02 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.76 50.0 3.89e-01 87.0% 32.2%
4ae7A00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.76 54.0 3.67e-01 92.6% 22.0%
4l8hB00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.72 51.0 3.94e-01 75.9% 43.1%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.72 50.0 4.43e-01 75.9% 50.6%
2cztA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.71 53.0 3.81e-01 79.6% 47.7%
4mbrA02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.68 60.0 4.19e-01 98.1% 85.5%
1vp2A00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.68 59.0 4.07e-01 100.0% 54.5%
2v1oB00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.66 49.0 3.60e-01 96.3% 29.7%
2qrdB01 2.20.25.290 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.66 42.0 4.77e-01 72.2% 97.3%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.65 45.0 4.13e-01 74.1% 55.4%
3b7kB01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.65 48.0 3.60e-01 96.3% 31.4%
1njkA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.64 55.0 4.22e-01 100.0% 42.1%
2a1rB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 55.0 3.51e-01 100.0% 52.4%
2ia7A00 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 44.0 3.57e-01 90.7% 36.9%
1wchA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.63 47.0 3.02e-01 88.9% 15.3%
1lhpA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.62 50.0 3.14e-01 100.0% 16.0%
4qunA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.61 46.0 3.00e-01 88.9% 16.6%
3ulpD00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 53.0 4.17e-01 98.1% 85.8%
1qftB00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.61 53.0 3.75e-01 98.1% 41.4%
3ecrB03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.60 52.0 4.21e-01 100.0% 51.0%
5t89X04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 49.0 4.07e-01 88.9% 63.4%
3ubfA03 2.60.40.60 Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins 0.60 48.0 3.95e-01 90.7% 63.7%
2bzlA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.59 45.0 2.91e-01 88.9% 15.8%
3njaA02 2.10.70.100 Mainly Beta › Ribbon › Complement Module; domain 1 › 0.59 40.0 4.24e-01 70.4% 95.7%
4kh8A01 2.40.128.540 Mainly Beta › Beta Barrel › Lipocalin › Domain of unknown function DUF4822 0.58 39.0 2.82e-01 75.9% 22.3%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.58 41.0 3.31e-01 87.0% 38.2%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 43.0 2.86e-01 83.3% 31.5%
3dsbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.58 39.0 3.22e-01 70.4% 40.6%
4ge6A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 43.0 2.78e-01 87.0% 15.2%
3zs7A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.57 49.0 3.14e-01 100.0% 27.4%
5swiD01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.57 49.0 3.23e-01 100.0% 22.1%
1ni9A01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.57 42.0 3.14e-01 90.7% 29.8%
6i8xA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 42.0 3.16e-01 87.0% 36.9%
4pkcC00 6.20.90.20 Special › Other non-globular › SH3 type barrels. › Benzylsuccinate synthase gamma subunit 0.55 39.0 4.22e-01 98.1% 100.0%
2b39A03 2.60.40.1940 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 45.0 3.62e-01 100.0% 70.4%
1n9pA00 2.60.40.1400 Mainly Beta › Sandwich › Immunoglobulin-like › G protein-activated inward rectifier potassium channel 1 0.55 46.0 3.19e-01 96.3% 67.5%
2hqlA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 42.0 3.72e-01 98.1% 53.8%
6u5vB07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.55 41.0 3.18e-01 92.6% 34.9%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 47.0 3.79e-01 98.1% 64.2%
3u4kA00 2.60.40.3310 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 42.0 3.06e-01 87.0% 32.5%
6u5uG07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.54 41.0 3.20e-01 85.2% 54.5%
7arcC01 3.30.460.80 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › NADH:ubiquinone oxidoreductase Nqo5 subunit 0.54 46.0 3.52e-01 100.0% 52.6%
2o1qA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.54 47.0 3.62e-01 100.0% 85.8%
1zc3B00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 46.0 3.74e-01 100.0% 70.6%
1e5pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.53 45.0 3.38e-01 100.0% 36.9%
1w96C04 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.52 37.0 2.43e-01 75.9% 98.4%
1pguA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 44.0 2.77e-01 100.0% 35.5%
2yfsA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 42.0 2.52e-01 100.0% 29.5%
2h2yA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.51 45.0 3.53e-01 100.0% 70.7%
7pkwA01 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 36.0 3.10e-01 90.7% 41.7%
3rhtA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.51 42.0 2.80e-01 98.1% 51.6%
2uytA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 43.0 2.87e-01 100.0% 23.0%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4187672 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.81 53.0 4.77e-01 74.1% 49.3%
4638542 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.80 53.0 4.33e-01 74.1% 38.9%
4048220 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.80 53.0 4.61e-01 74.1% 46.3%
4434012 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.80 55.0 4.67e-01 74.1% 45.9%
4004011 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.79 53.0 4.14e-01 70.4% 36.4%
4638787 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.78 52.0 4.58e-01 74.1% 47.5%
5037441 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.77 52.0 4.09e-01 70.4% 34.5%
4175367 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.76 52.0 4.41e-01 90.7% 43.3%
3594465 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.76 51.0 5.15e-01 70.4% 69.1%
3267746 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.76 53.0 4.56e-01 74.1% 49.4%
4135153 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.75 50.0 4.52e-01 74.1% 50.7%
5023443 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.75 50.0 4.74e-01 74.1% 58.5%
4609498 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.75 52.0 4.57e-01 100.0% 50.0%
4054729 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.74 50.0 4.48e-01 74.1% 50.7%
2640602 222.1.1.4 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT 0.74 53.0 4.19e-01 100.0% 37.6%
4552605 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 49.0 4.39e-01 74.1% 48.7%
4611568 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 49.0 4.41e-01 74.1% 50.7%
3194095 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.72 54.0 4.44e-01 85.2% 45.3%
222972 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.72 50.0 4.26e-01 75.9% 44.9%
3937984 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.71 48.0 3.90e-01 70.4% 39.0%
5067760 283.1.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase 0.70 47.0 3.98e-01 92.6% 42.2%
4161565 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.69 54.0 4.47e-01 100.0% 48.4%
3292852 4086.1.1.1 a+b two layers › AMPKBI-like › AMPKBI-like › AMPKBI-like › AMPKBI 0.69 46.0 3.84e-01 88.9% 40.0%
3735671 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.68 52.0 4.29e-01 85.2% 45.0%
3272363 4.1.1.219 beta barrels › SH3 › SH3 › SH3 › LSM12_LSM 0.68 50.0 4.16e-01 96.3% 45.3%
3579667 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.66 47.0 3.53e-01 75.9% 60.0%
4213219 109.21.1.0 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain 0.66 45.0 2.52e-01 94.4% 5.0%
3472467 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.66 45.0 4.08e-01 74.1% 52.0%
3991437 2003.1.5.13 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.65 51.0 3.33e-01 83.3% 94.7%
3488611 383.1.2.0 few secondary structure elements › Defensin-like › Defensin-related › Laterosporulin 0.65 44.0 4.84e-01 90.7% 97.5%
3495550 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 46.0 3.83e-01 100.0% 40.0%
3229184 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.64 47.0 4.03e-01 96.3% 49.4%
5003966 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.64 42.0 3.96e-01 74.1% 56.9%
3445096 5.1.3.68 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF1618 0.63 54.0 3.23e-01 94.4% 83.6%
3228385 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.63 44.0 2.49e-01 94.4% 6.5%
5030187 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.62 55.0 4.85e-01 98.1% 92.3%
3924626 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.62 46.0 4.00e-01 100.0% 50.6%
3601940 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 49.0 4.08e-01 88.9% 70.0%
3855356 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.62 46.0 2.97e-01 88.9% 15.0%
3393619 284.4.1.2 a+b two layers › FKBP-like › Archaeal FKBP insertion domain › Archaeal FKBP insertion domain › PF28923 0.62 47.0 4.82e-01 96.3% 90.0%
3938060 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.61 46.0 3.39e-01 88.9% 27.4%
3650660 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.61 48.0 3.63e-01 87.0% 35.1%
3417120 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.61 53.0 4.15e-01 100.0% 52.5%
3272078 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.60 44.0 2.79e-01 77.8% 33.9%
3592202 2003.6.1.0 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like 0.60 51.0 3.22e-01 100.0% 26.3%
3818651 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.60 50.0 3.26e-01 100.0% 58.1%
1149748 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.59 51.0 3.87e-01 100.0% 77.9%
3883616 378.1.1.1 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › Endonuclease_NS 0.59 42.0 2.81e-01 81.5% 20.4%
3827488 319.1.1.15 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PF27746 0.58 51.0 4.09e-01 100.0% 58.2%
3479794 2007.2.3.0 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II 0.57 43.0 2.74e-01 87.0% 14.1%
3173378 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.57 43.0 2.87e-01 85.2% 34.3%
3697470 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 49.0 2.92e-01 100.0% 96.5%
3992783 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 41.0 2.75e-01 100.0% 18.3%
3466675 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.56 46.0 3.50e-01 100.0% 77.3%
3404964 221.13.1.0 a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.55 46.0 3.74e-01 100.0% 82.6%
3208851 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.55 48.0 3.73e-01 98.1% 68.3%
3265659 11.1.5.62 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › CBM49 0.55 48.0 4.00e-01 98.1% 89.5%
3937109 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.54 47.0 2.93e-01 100.0% 30.0%
1822815 6173.1.1.1 beta barrels › V1/V2 domain in HIV gp120 › V1/V2 domain in HIV gp120 › V1/V2 domain in HIV gp120 › GP120 0.54 39.0 4.09e-01 87.0% 87.5%
4929017 1.1.2.0 beta barrels › cradle loop barrel › RIFT-related › double psi 0.54 45.0 3.53e-01 98.1% 87.2%
4483987 374.1.1.2 few secondary structure elements › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) › HIPIP (high potential iron protein) › BssC_TutF 0.53 36.0 3.61e-01 72.2% 76.4%
4928623 1.1.2.16 beta barrels › cradle loop barrel › RIFT-related › double psi › MacB_PCD 0.53 45.0 3.15e-01 100.0% 57.9%
3577471 221.13.1.0 a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.53 44.0 3.46e-01 100.0% 83.8%
3709133 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.50 40.0 3.33e-01 100.0% 55.0%