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KP054477.1__AIZ94722.1__LfeInf_096__00096

Bact-Vir

KP054477.1__AIZ94722.1__LfeInf_096__00096

Identity

Accession:
KP054477 ↗
Kingdom:
phage

Quality

85.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 53-210
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07659.17 best DUF1599 30.4 5.50e-07 41.8% 98.4%
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.79 44.0 5.17e-01 98.1% 77.0%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.78 44.0 5.07e-01 98.7% 74.6%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.77 42.0 4.28e-01 98.7% 54.5%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.75 42.0 4.41e-01 98.7% 59.2%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.74 49.0 4.73e-01 98.7% 59.6%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 42.0 4.90e-01 95.6% 76.1%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.74 42.0 4.87e-01 97.5% 77.2%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.72 42.0 4.89e-01 95.6% 79.3%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.70 46.0 4.39e-01 98.1% 57.1%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 53.0 4.71e-01 77.2% 83.6%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.69 44.0 4.92e-01 96.8% 79.1%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 39.0 3.70e-01 98.1% 46.2%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.69 38.0 3.88e-01 97.5% 54.5%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.69 42.0 5.27e-01 96.8% 100.0%
4gycA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 52.0 4.63e-01 78.5% 85.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 40.0 5.04e-01 97.5% 98.9%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.68 34.0 4.68e-01 95.6% 96.2%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.68 41.0 5.14e-01 98.1% 100.0%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 43.0 5.20e-01 99.4% 97.1%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.67 44.0 4.56e-01 98.1% 70.1%
1cgnA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.66 42.0 4.72e-01 98.7% 80.6%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 43.0 4.85e-01 99.4% 83.9%
1i5pA02 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.66 41.0 3.55e-01 99.4% 41.0%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 44.0 5.06e-01 76.6% 92.4%
4l6rA02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 48.0 3.94e-01 77.8% 75.0%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.64 45.0 4.41e-01 99.4% 66.9%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 48.0 4.01e-01 79.1% 78.7%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 36.0 4.11e-01 88.6% 73.7%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.62 43.0 4.70e-01 79.7% 85.0%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 40.0 4.71e-01 99.4% 95.4%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.61 43.0 4.46e-01 99.4% 77.4%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 36.0 3.79e-01 96.8% 63.6%
3fhnA01 6.10.280.210 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A 0.61 37.0 3.56e-01 100.0% 51.1%
6gyhA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 46.0 4.08e-01 78.5% 84.0%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.60 41.0 3.73e-01 98.1% 50.9%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.60 47.0 4.18e-01 81.0% 94.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 40.0 4.74e-01 99.4% 100.0%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 45.0 4.87e-01 78.5% 92.7%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 47.0 4.88e-01 82.3% 95.2%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 36.0 3.76e-01 96.8% 63.3%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 41.0 4.72e-01 71.5% 100.0%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 42.0 3.71e-01 98.7% 50.9%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 37.0 4.42e-01 98.1% 97.1%
7cfmR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 43.0 3.69e-01 77.2% 90.1%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.58 42.0 4.54e-01 80.4% 88.5%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 35.0 3.76e-01 96.2% 68.1%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.58 35.0 3.84e-01 97.5% 73.2%
4k1pE00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.57 51.0 4.04e-01 97.5% 73.2%
3geeA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.57 44.0 4.37e-01 80.4% 81.5%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 52.0 4.01e-01 100.0% 71.7%
1txdA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.56 40.0 3.57e-01 100.0% 51.1%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 41.0 4.54e-01 75.9% 100.0%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 41.0 4.33e-01 77.8% 86.7%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.54 51.0 3.99e-01 98.1% 63.4%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 38.0 3.76e-01 99.4% 67.5%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 37.0 3.74e-01 99.4% 70.8%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 37.0 3.77e-01 99.4% 73.3%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.53 37.0 3.83e-01 95.6% 74.5%
4pypA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 48.0 3.49e-01 100.0% 76.1%
2nrjA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.53 48.0 3.74e-01 98.7% 65.8%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.52 38.0 4.29e-01 77.8% 96.7%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.52 48.0 3.68e-01 100.0% 74.6%
4m7cB00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.51 37.0 3.43e-01 74.1% 69.2%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 36.0 3.70e-01 100.0% 75.2%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3693766 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 45.0 5.26e-01 98.7% 80.9%
3683068 109.62.1.3 alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 0.76 46.0 4.33e-01 100.0% 50.5%
3498895 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 45.0 4.73e-01 97.5% 64.1%
3806852 109.62.1.3 alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › THD_CWZF3-5-7 0.76 46.0 4.23e-01 100.0% 47.3%
3238969 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.75 45.0 4.75e-01 100.0% 64.8%
4192155 601.1.1.43 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A 0.75 44.0 5.06e-01 100.0% 77.5%
3691982 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 67.0 6.67e-01 98.7% 97.0%
4017640 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 43.0 5.09e-01 98.7% 91.7%
4934609 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 42.0 4.61e-01 98.7% 76.2%
3776730 5001.1.1.9 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R 0.66 50.0 3.91e-01 77.8% 77.5%
2703780 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.65 50.0 4.80e-01 100.0% 70.7%
4432227 604.1.1.161 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27599 0.65 42.0 3.82e-01 100.0% 48.8%
5043439 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.64 48.0 4.39e-01 77.2% 60.8%
3796694 5050.1.1.22 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like 0.64 49.0 4.75e-01 79.7% 72.0%
3995508 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.64 49.0 5.22e-01 79.1% 92.6%
3224443 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.63 47.0 3.89e-01 77.8% 44.8%
3238458 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 47.0 4.09e-01 79.1% 96.3%
3879763 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 47.0 3.93e-01 77.8% 46.8%
4958850 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.62 37.0 4.75e-01 91.1% 100.0%
5025484 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 46.0 4.13e-01 76.6% 56.9%
3894248 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 46.0 3.93e-01 77.8% 48.6%
3554055 3567.1.1.12 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › CD47 0.62 40.0 3.90e-01 98.7% 59.4%
5021085 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.61 46.0 3.51e-01 78.5% 66.3%
3909548 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.61 45.0 4.45e-01 98.1% 72.1%
3623280 603.1.1.110 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.61 41.0 3.88e-01 100.0% 55.9%
3400991 3615.1.1.29 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › DUF7775 0.61 45.0 4.55e-01 98.1% 76.8%
3499026 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.60 42.0 4.30e-01 99.4% 73.5%
3463158 601.18.1.1 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ 0.59 44.0 4.98e-01 77.8% 100.0%
4591989 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.59 51.0 3.82e-01 92.4% 85.6%
4592540 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.59 46.0 4.54e-01 81.0% 84.7%
5047040 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.59 44.0 4.07e-01 78.5% 82.4%
3933640 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.59 46.0 4.05e-01 82.9% 60.4%
3498285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 45.0 4.73e-01 79.7% 89.3%
3225005 192.29.1.31 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CRIC_ras_sig 0.58 44.0 4.80e-01 77.8% 94.6%
3897356 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.57 41.0 3.72e-01 99.4% 54.8%
4191633 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.57 40.0 3.59e-01 72.2% 83.9%
4018439 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.56 40.0 4.11e-01 96.8% 74.8%
5047358 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 45.0 4.44e-01 84.8% 95.3%
4989670 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 51.0 4.62e-01 97.5% 85.7%
5034794 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 50.0 4.49e-01 94.9% 79.5%
2595282 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.56 51.0 3.92e-01 99.4% 69.3%
4357809 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.56 43.0 4.30e-01 98.7% 78.8%
3575241 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.55 43.0 4.10e-01 100.0% 70.6%
5029119 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.55 39.0 4.32e-01 72.8% 98.3%
5052627 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.54 46.0 4.12e-01 93.7% 72.6%
3838201 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.54 46.0 4.43e-01 91.1% 84.6%
5039672 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.54 43.0 4.17e-01 93.0% 75.0%
3662240 601.1.1.70 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › ROH1-like 0.54 41.0 4.54e-01 82.3% 97.7%
3421415 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.53 38.0 4.03e-01 74.1% 100.0%
3209356 601.11.1.2 alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › DUF3433 0.53 40.0 3.81e-01 77.8% 85.9%
4026210 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.53 48.0 4.37e-01 99.4% 76.7%
3774198 601.3.1.4 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PTPLA 0.52 47.0 4.25e-01 97.5% 73.5%
3702300 606.1.1.1 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.52 49.0 4.63e-01 100.0% 93.0%
3255819 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.52 46.0 4.16e-01 95.6% 85.6%
3895523 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.52 47.0 4.24e-01 98.1% 73.0%
3711985 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.52 47.0 3.99e-01 100.0% 61.2%
3733226 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.52 44.0 4.28e-01 95.6% 81.7%
3879758 192.29.1.50 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA 0.52 47.0 4.29e-01 98.7% 76.2%
4158967 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.52 46.0 4.38e-01 98.1% 86.3%
3264561 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.52 46.0 4.00e-01 98.1% 68.2%
3899656 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.52 49.0 3.78e-01 99.4% 84.4%
3592057 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.51 46.0 4.17e-01 100.0% 72.9%
4441193 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.51 37.0 3.32e-01 74.1% 85.3%
4053331 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.51 38.0 3.04e-01 77.8% 93.3%
4025583 636.1.1.0 alpha arrays › SopE-like GEF domain › SopE-like GEF domain › SopE-like GEF domain 0.51 36.0 3.43e-01 72.2% 86.8%
3471820 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 48.0 4.15e-01 100.0% 72.2%
3458922 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.50 37.0 3.36e-01 77.2% 92.4%
D2 medium residues 1-52
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3weeB03 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.67 52.0 4.11e-01 88.5% 67.8%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.66 46.0 3.84e-01 73.1% 65.2%
2xcqA02 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.64 46.0 2.89e-01 75.0% 29.2%
2pe4A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.63 53.0 3.16e-01 98.1% 22.5%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 52.0 4.19e-01 98.1% 47.2%
1pc6A00 1.10.3790.10 Mainly Alpha › Orthogonal Bundle › NinB fold › NinB 0.61 45.0 3.35e-01 80.8% 65.2%
3pjvD01 3.30.110.200 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › 0.61 53.0 4.70e-01 100.0% 75.6%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.59 46.0 3.15e-01 88.5% 75.6%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.58 40.0 3.41e-01 75.0% 47.4%
1o97D01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 40.0 2.75e-01 73.1% 82.5%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.58 43.0 3.16e-01 84.6% 32.7%
4xr7F02 1.10.287.3700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 44.0 3.69e-01 84.6% 83.3%
3ibvB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 49.0 2.68e-01 96.2% 8.9%
3ddjA01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.56 38.0 2.95e-01 73.1% 91.9%
1aihA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.56 43.0 3.09e-01 86.5% 28.2%
6c1qB02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 48.0 2.99e-01 96.2% 17.9%
4bwxA03 1.10.287.3700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 38.0 3.41e-01 73.1% 80.0%
1td6A02 3.30.1790.10 Alpha Beta › 2-Layer Sandwich › hypothetical protein mp506/mpn330, domain 2 › hypothetical protein mp506/mpn330, domain 2 0.56 38.0 3.25e-01 73.1% 46.7%
4mt1A07 3.30.70.1440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.55 43.0 3.48e-01 86.5% 78.4%
3aa0B01 1.20.58.570 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › F-actin capping protein, alpha/beta subunit, N-terminal domain 0.54 37.0 3.20e-01 73.1% 52.3%
3f1yA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.54 42.0 2.69e-01 92.3% 49.1%
4g1uD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 38.0 2.49e-01 80.8% 22.2%
1ybyA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 33.0 3.13e-01 73.1% 51.6%
1s1dA00 2.120.10.100 Mainly Beta › 6 Propeller › Neuraminidase › Apyrase 0.51 36.0 2.28e-01 76.9% 31.2%
3hwuA00 3.30.1330.80 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 0.50 34.0 2.69e-01 75.0% 45.1%
3gbyA00 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.50 36.0 2.81e-01 78.8% 92.9%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3179675 3873.1.1.1 a+b two layers › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › HGTP_anticodon2 0.73 46.0 3.51e-01 88.5% 27.5%
3988933 3227.1.1.1 alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC 0.73 53.0 3.10e-01 84.6% 9.9%
4015596 3873.1.1.0 a+b two layers › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain › Serine/threonine-protein kinase GCN2 C-terminal domain 0.71 52.0 4.00e-01 78.8% 39.2%
3590646 101.1.2.16 alpha arrays › HTH › HTH › winged helix domain › Rep3_N 0.69 51.0 3.90e-01 80.8% 78.4%
5078411 7592.1.1.6 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N 0.69 48.0 3.46e-01 73.1% 37.1%
3882204 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.67 56.0 3.42e-01 92.3% 36.1%
4778018 1016.1.1.1 alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Pan3_PK 0.66 45.0 3.92e-01 73.1% 80.5%
2388540 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 48.0 3.25e-01 78.8% 46.7%
1207585 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.65 44.0 3.82e-01 80.8% 45.7%
3547914 70.4.1.5 beta barrels › beta-clip › Head decoration protein D (gpD, major capsid protein D) › Head decoration protein D (gpD, major capsid protein D) › LMF1 0.65 47.0 2.90e-01 96.2% 13.3%
3903882 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 50.0 3.10e-01 84.6% 35.2%
3641285 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.62 46.0 2.63e-01 80.8% 9.4%
4357829 2003.1.1.28 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.62 48.0 3.47e-01 90.4% 86.3%
3238722 2003.1.2.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like 0.62 46.0 2.83e-01 78.8% 77.6%
4976626 3714.1.1.0 a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain 0.62 55.0 3.57e-01 98.1% 23.1%
3785389 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.61 42.0 4.18e-01 73.1% 100.0%
3515089 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.61 42.0 3.85e-01 71.2% 95.6%
3935356 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.61 49.0 3.74e-01 88.5% 38.3%
4297075 286.1.1.1 a+b complex topology › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › Diaminopimelate epimerase-like › DAP_epimerase 0.60 45.0 3.40e-01 82.7% 60.7%
4999182 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 40.0 3.66e-01 71.2% 90.7%
None 0.59 53.0 3.23e-01 100.0% 41.6%
3506749 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.59 46.0 3.27e-01 86.5% 73.9%
3497696 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.59 52.0 3.16e-01 100.0% 38.8%
3671232 109.4.1.1610 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, E_motif 0.59 41.0 2.50e-01 73.1% 27.7%
3803650 109.4.1.1335 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, E_motif 0.59 46.0 2.62e-01 88.5% 16.2%
None 0.59 52.0 3.21e-01 100.0% 44.4%
3395806 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 50.0 3.09e-01 98.1% 71.1%
4987009 3837.1.1.1 alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 0.58 50.0 3.58e-01 100.0% 33.3%
3958386 101.1.2.670 alpha arrays › HTH › HTH › winged helix domain › DUF4194 0.58 41.0 3.59e-01 76.9% 92.5%
3394225 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.58 45.0 3.72e-01 96.2% 43.5%
4065083 4203.1.1.1 few secondary structure elements › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 0.56 38.0 3.82e-01 71.2% 72.7%
3929449 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 48.0 3.25e-01 100.0% 53.8%
5023832 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.55 38.0 3.51e-01 75.0% 62.7%
3468311 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.55 44.0 2.63e-01 86.5% 14.9%
3974319 2005.1.1.10 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ETF 0.54 37.0 2.58e-01 73.1% 80.5%
3291165 223.3.1.2 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Peptidase_S11 0.54 39.0 2.87e-01 78.8% 52.8%
3652752 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.53 40.0 2.62e-01 88.5% 18.3%
3335423 109.4.1.1993 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif, TPR_24 0.52 40.0 2.33e-01 100.0% 21.4%
3061774 223.3.1.8 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase2 0.50 34.0 3.53e-01 71.2% 95.5%
4467601 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.50 42.0 2.74e-01 96.2% 30.0%