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KP836355.1__AJW76922.1__UF08_33__00033

Bact-Vir

KP836355.1__AJW76922.1__UF08_33__00033

Identity

Accession:
KP836355 ↗
Kingdom:
phage

Quality

85.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 6-120_181-200
PDB
Domain cluster: representative
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.74 64.0 5.96e-01 91.9% 98.2%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.72 44.0 4.52e-01 91.1% 63.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 43.0 4.96e-01 72.6% 81.6%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.70 57.0 5.70e-01 85.2% 100.0%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.70 61.0 5.58e-01 94.1% 94.9%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 56.0 5.12e-01 85.2% 70.3%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 42.0 4.89e-01 83.0% 84.5%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 56.0 5.91e-01 97.8% 95.8%
4p79A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.68 53.0 4.78e-01 81.5% 80.7%
7yu4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 62.0 4.98e-01 100.0% 83.7%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 54.0 5.16e-01 84.4% 76.1%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 54.0 5.77e-01 85.2% 100.0%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.67 58.0 5.32e-01 91.1% 75.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 53.0 5.68e-01 83.7% 100.0%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.67 51.0 4.51e-01 80.0% 86.5%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 50.0 4.40e-01 77.0% 88.8%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 57.0 5.79e-01 92.6% 98.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.65 43.0 4.59e-01 81.5% 77.2%
1qkrB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 61.0 5.46e-01 100.0% 77.2%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 52.0 5.15e-01 85.2% 83.9%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 51.0 5.09e-01 84.4% 83.0%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 51.0 4.84e-01 84.4% 75.3%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 59.0 4.98e-01 100.0% 65.6%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 47.0 3.59e-01 75.6% 77.8%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.63 39.0 4.18e-01 71.1% 69.2%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.63 53.0 5.04e-01 91.9% 77.2%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 50.0 4.88e-01 84.4% 78.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.61 50.0 5.32e-01 91.1% 100.0%
5azsC01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.60 53.0 3.76e-01 91.1% 46.1%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 48.0 4.69e-01 84.4% 82.4%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 46.0 4.78e-01 79.3% 92.6%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 45.0 4.84e-01 79.3% 90.6%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.60 48.0 5.10e-01 88.1% 96.6%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.60 44.0 4.33e-01 77.8% 85.8%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 42.0 4.71e-01 87.4% 97.1%
3lomA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 54.0 4.19e-01 100.0% 52.8%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.58 42.0 3.79e-01 74.8% 87.0%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.58 41.0 3.97e-01 71.1% 79.6%
3ug9A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 52.0 4.40e-01 98.5% 85.3%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 44.0 4.04e-01 80.7% 70.5%
1kqfC00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.56 48.0 4.19e-01 94.8% 90.7%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 43.0 4.38e-01 84.4% 91.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 42.0 4.42e-01 82.2% 89.2%
3thxB03 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.54 48.0 4.38e-01 97.8% 73.9%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.54 47.0 4.33e-01 91.9% 95.8%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.53 42.0 4.00e-01 85.2% 79.3%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 39.0 3.48e-01 77.0% 77.5%
3kkdA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 38.0 3.43e-01 78.5% 91.4%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4928764 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.84 74.0 6.96e-01 92.6% 98.8%
5043437 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.74 50.0 5.62e-01 83.7% 87.6%
4942916 601.12.1.1 alpha bundles › Four-helical up-and-down bundle › Nickel-containing superoxide dismutase, NiSOD › Nickel-containing superoxide dismutase, NiSOD › Sod_Ni 0.73 63.0 6.01e-01 91.1% 80.6%
3225939 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 59.0 6.04e-01 91.1% 90.0%
2671884 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.71 59.0 5.70e-01 88.1% 89.4%
3407613 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.70 43.0 4.35e-01 76.3% 60.9%
4484295 192.29.1.165 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29336 0.70 60.0 6.04e-01 91.9% 100.0%
5036796 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 59.0 5.91e-01 91.9% 93.6%
5061688 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.69 58.0 5.80e-01 89.6% 95.0%
3171851 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.69 58.0 5.53e-01 91.1% 88.7%
3928099 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 62.0 5.02e-01 98.5% 92.5%
3511227 601.15.1.2 alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C 0.69 59.0 5.27e-01 92.6% 97.4%
3211056 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 50.0 4.61e-01 77.0% 60.0%
3740863 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.68 58.0 4.92e-01 90.4% 69.3%
5054707 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.67 61.0 5.21e-01 100.0% 88.6%
3623521 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.67 62.0 4.73e-01 100.0% 84.9%
3393867 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.67 57.0 5.91e-01 89.6% 96.8%
3253935 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.67 55.0 5.83e-01 87.4% 100.0%
3967683 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.66 58.0 5.63e-01 93.3% 95.3%
3933806 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 48.0 4.92e-01 85.9% 76.9%
3780808 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.66 38.0 4.03e-01 76.3% 63.6%
3650806 5001.1.1.23 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GOST_TM 0.66 60.0 4.77e-01 100.0% 85.6%
4220561 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.66 56.0 5.75e-01 91.9% 93.8%
3838108 192.29.1.123 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › UPF0093 0.66 54.0 5.36e-01 88.9% 98.6%
3940161 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.65 56.0 5.15e-01 92.6% 74.9%
3289746 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.65 57.0 4.59e-01 97.8% 72.4%
4156067 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.65 48.0 5.26e-01 76.3% 100.0%
5053834 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 54.0 4.97e-01 88.9% 82.4%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 54.0 5.68e-01 90.4% 100.0%
3670390 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.64 59.0 4.68e-01 100.0% 97.4%
3413818 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.64 47.0 4.70e-01 81.5% 72.1%
5010298 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 51.0 4.70e-01 81.5% 98.2%
3369628 3684.1.1.10 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 0.63 54.0 4.57e-01 92.6% 88.9%
5075780 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.63 50.0 5.09e-01 85.9% 100.0%
5070649 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.62 46.0 2.83e-01 76.3% 30.5%
5031982 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.62 53.0 4.94e-01 91.1% 84.8%
5036521 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.62 53.0 5.10e-01 92.6% 94.8%
3834068 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.62 52.0 4.40e-01 90.4% 60.1%
3281911 601.4.1.2 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT 0.61 49.0 5.15e-01 89.6% 95.8%
3868831 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.61 47.0 4.42e-01 81.5% 66.7%
3399701 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 41.0 4.05e-01 85.9% 65.0%
3862009 3755.3.1.293 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH 0.61 49.0 4.65e-01 85.2% 90.0%
5038395 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.61 53.0 5.03e-01 92.6% 89.0%
3962324 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.60 44.0 3.80e-01 74.8% 75.0%
3556701 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 46.0 4.38e-01 79.3% 72.3%
3625558 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 42.0 4.20e-01 78.5% 70.4%
3626002 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.60 52.0 4.91e-01 100.0% 78.0%
3840817 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.60 45.0 4.10e-01 77.0% 85.7%
3989931 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.60 51.0 4.46e-01 90.4% 88.7%
3405706 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.60 43.0 4.41e-01 85.9% 77.7%
3771262 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.59 44.0 4.21e-01 76.3% 96.1%
3432720 604.1.1.118 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.59 44.0 4.36e-01 78.5% 73.1%
3626316 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.59 40.0 4.14e-01 85.9% 72.3%
4398872 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.59 47.0 4.51e-01 85.9% 73.1%
3887929 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.59 41.0 4.33e-01 77.0% 80.0%
3417703 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 44.0 4.12e-01 80.7% 63.6%
5045646 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 49.0 4.87e-01 91.9% 97.9%
3197870 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 46.0 4.63e-01 83.0% 82.2%
4001943 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 39.0 4.17e-01 85.9% 77.5%
3899721 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.58 44.0 4.18e-01 81.5% 70.9%
3956826 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.57 48.0 4.42e-01 88.1% 92.4%
3923182 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.57 44.0 4.28e-01 80.7% 81.3%
4600429 5069.1.3.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt 0.56 42.0 4.45e-01 77.8% 91.7%
4176577 601.1.2.3 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C 0.56 41.0 4.17e-01 74.8% 90.0%
4012748 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.56 44.0 3.39e-01 83.7% 44.8%
4846601 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.56 37.0 3.88e-01 81.5% 73.8%
3806304 633.22.1.0 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.53 38.0 3.55e-01 74.1% 97.1%
5057940 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.53 41.0 3.52e-01 81.5% 63.8%
3973161 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 45.0 3.96e-01 99.3% 65.7%
D2 medium residues 121-180
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.75 49.0 3.96e-01 90.0% 36.7%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.73 52.0 3.43e-01 75.0% 69.5%
4lgqA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 44.0 3.37e-01 90.0% 36.1%
3hm2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 41.0 3.10e-01 78.3% 29.2%
4q52A00 2.60.40.3910 Mainly Beta › Sandwich › Immunoglobulin-like › Inclusion body protein 0.57 46.0 3.40e-01 91.7% 87.4%
3k8aB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 41.0 3.49e-01 91.7% 46.6%
3d9rB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 40.0 3.16e-01 91.7% 35.3%
1nbwA02 3.90.470.30 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Coenzyme B12-Dependent Enzyme linker domain 0.55 39.0 3.18e-01 81.7% 88.1%
1l3iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 38.0 2.82e-01 75.0% 27.6%
2hn1A01 3.30.460.20 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › CorA soluble domain-like 0.55 44.0 3.42e-01 91.7% 82.4%
2yxdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 38.0 2.88e-01 78.3% 29.6%
5fohA00 2.70.50.70 Mainly Beta › Distorted Sandwich › Coagulation Factor XIII; Chain A, domain 1 › 0.53 41.0 2.92e-01 90.0% 65.1%
1av4A03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.53 46.0 2.79e-01 100.0% 36.1%
6xw5A01 2.40.510.10 Mainly Beta › Beta Barrel › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Positive stranded ssRNA viruses 0.53 42.0 3.14e-01 91.7% 87.3%
4f0aB02 3.30.2460.20 Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Wnt (Wingless and Int-1), C-terminal domain 0.53 42.0 4.11e-01 88.3% 89.7%
4ydzA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 39.0 3.19e-01 85.0% 68.1%
3ulpD00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 42.0 3.53e-01 93.3% 86.7%
1pfoA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.52 38.0 3.93e-01 81.7% 92.5%
1lyvA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.52 38.0 2.53e-01 81.7% 26.5%
7t4dA01 2.70.240.10 Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA 0.52 39.0 2.64e-01 88.3% 81.1%
2r5rA00 3.10.270.10 Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; 0.52 45.0 3.02e-01 98.3% 42.7%
2lxxA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.52 44.0 3.38e-01 100.0% 57.2%
3e05B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 36.0 2.69e-01 78.3% 91.1%
3ddcB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 44.0 3.48e-01 100.0% 72.9%
3kkgA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 37.0 2.87e-01 90.0% 33.3%
4bqqB02 3.90.1750.20 Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Putative Large Serine Recombinase; Chain B, Domain 2 0.51 35.0 2.57e-01 86.7% 23.7%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4635290 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.87 62.0 3.63e-01 75.0% 48.1%
4666185 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.85 61.0 3.60e-01 75.0% 48.0%
4088089 304.48.1.39 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.84 58.0 3.58e-01 71.7% 59.7%
4241274 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 60.0 3.52e-01 75.0% 46.1%
4223395 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.82 58.0 3.45e-01 75.0% 46.1%
4126255 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.82 56.0 3.55e-01 71.7% 29.5%
4544858 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 58.0 3.39e-01 75.0% 48.9%
4361292 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 58.0 3.36e-01 75.0% 48.3%
4486052 304.48.1.39 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N 0.81 57.0 3.51e-01 75.0% 64.7%
4396101 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.79 57.0 3.39e-01 78.3% 51.1%
3220090 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.75 53.0 3.08e-01 73.3% 80.0%
4552467 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.75 55.0 3.39e-01 78.3% 56.2%
4442725 4967.1.1.25 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.69 50.0 2.92e-01 75.0% 49.8%
4012024 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.69 49.0 3.20e-01 76.7% 28.2%
4856794 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.65 48.0 4.43e-01 91.7% 62.3%
3517061 11.12.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD 0.64 55.0 3.83e-01 95.0% 95.4%
3989031 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.63 47.0 3.10e-01 80.0% 30.0%
3614657 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.63 50.0 2.96e-01 88.3% 21.0%
4951650 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.63 47.0 3.09e-01 81.7% 31.3%
3611566 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.63 54.0 3.26e-01 100.0% 26.4%
3624550 6043.1.1.4 a+b two layers › yfeY-like › yfeY-like › yfeY-like › PHAF1 0.62 46.0 3.49e-01 91.7% 32.7%
4996611 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.62 50.0 3.72e-01 88.3% 44.7%
4965880 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.61 44.0 2.96e-01 78.3% 61.6%
3736890 5.1.5.236 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Beta-prop_WDR3_1st 0.58 49.0 2.80e-01 100.0% 16.1%
4305190 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.56 49.0 3.83e-01 98.3% 88.5%
3452174 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.56 44.0 3.31e-01 90.0% 37.7%
4989866 205.1.1.17 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_11 0.55 41.0 2.87e-01 100.0% 22.7%
4120121 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.55 48.0 3.89e-01 96.7% 94.5%
3663237 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.55 40.0 3.65e-01 93.3% 57.5%
4635289 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.55 46.0 2.86e-01 100.0% 45.9%
4629438 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.54 47.0 3.85e-01 96.7% 94.5%
4196358 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.54 47.0 3.76e-01 98.3% 90.8%
4014355 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.54 42.0 3.83e-01 90.0% 62.4%
4484391 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.54 47.0 3.71e-01 98.3% 84.0%
3193892 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.54 44.0 2.49e-01 100.0% 13.2%
4240255 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.53 46.0 3.77e-01 98.3% 90.4%
4488222 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.53 46.0 3.59e-01 96.7% 80.8%
5016531 11.1.1.347 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › T26-6p_Ig-like_dom_2 0.53 41.0 2.65e-01 95.0% 86.6%
3933752 11.1.1.178 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_2 0.53 36.0 2.85e-01 75.0% 62.0%
4990821 7571.1.1.1 a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N 0.53 41.0 2.81e-01 95.0% 57.8%
3601924 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.52 42.0 3.22e-01 100.0% 58.9%
3416305 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.52 45.0 2.80e-01 100.0% 20.6%
3716792 511.1.1.0 beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.52 42.0 3.31e-01 98.3% 59.7%
4983910 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.52 43.0 3.46e-01 98.3% 90.8%
4236774 230.1.1.5 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.52 45.0 3.55e-01 98.3% 90.4%
2726885 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.51 39.0 3.36e-01 90.0% 90.3%
3582577 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.51 40.0 3.28e-01 100.0% 43.1%
5048021 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.51 41.0 2.86e-01 95.0% 31.7%
3282895 912.1.1.0 few secondary structure elements › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain 0.51 43.0 3.09e-01 98.3% 84.6%
3521712 109.6.1.1 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF 0.51 36.0 2.30e-01 80.0% 13.1%