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KT151959.1__ALA47820.1__SUNDANCE_4__00004

Bact-Vir

KT151959.1__ALA47820.1__SUNDANCE_4__00004

Identity

Accession:
KT151959 ↗
Kingdom:
phage

Quality

73.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 36-178
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xubA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 43.0 5.62e-01 72.0% 100.0%
4mtdD01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 43.0 5.37e-01 74.8% 100.0%
2nriB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 44.0 5.32e-01 85.3% 96.7%
1ulyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 39.0 4.77e-01 74.8% 92.1%
2ethA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 40.0 4.06e-01 72.0% 59.6%
1sfxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 38.0 4.36e-01 73.4% 77.9%
2v79A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 39.0 4.32e-01 75.5% 81.7%
1whwA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 27.0 3.18e-01 79.7% 69.1%
1zybA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.53 41.0 3.54e-01 81.1% 80.7%
2oayA01 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.53 39.0 3.58e-01 76.9% 100.0%
1epuA03 1.25.40.60 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 33.0 3.55e-01 76.9% 75.8%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5023773 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.75 49.0 4.55e-01 71.3% 53.1%
4004118 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.73 47.0 4.27e-01 79.7% 49.2%
4993652 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.73 46.0 4.28e-01 74.8% 51.4%
4029392 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.72 50.0 4.54e-01 84.6% 54.6%
5039984 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.72 48.0 4.55e-01 84.6% 58.2%
4466102 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.70 42.0 3.98e-01 73.4% 50.0%
4239635 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.70 45.0 4.27e-01 79.7% 55.8%
4527101 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.70 43.0 4.16e-01 76.2% 55.0%
5011468 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.69 40.0 4.30e-01 71.3% 64.8%
4478999 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.69 46.0 4.29e-01 79.7% 54.9%
5080684 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.69 44.0 4.29e-01 79.0% 58.7%
4438513 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.68 44.0 4.98e-01 79.0% 84.5%
5048188 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 45.0 4.35e-01 72.7% 59.4%
4930596 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.68 47.0 4.47e-01 90.2% 60.0%
4403519 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.68 43.0 4.03e-01 78.3% 52.9%
5041543 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.68 43.0 4.39e-01 75.5% 65.0%
4456198 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.67 49.0 4.48e-01 85.3% 57.8%
5075111 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.67 46.0 4.61e-01 84.6% 68.1%
4974744 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.67 42.0 3.90e-01 76.9% 50.9%
5032906 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.67 50.0 5.04e-01 84.6% 78.6%
4943395 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.67 45.0 4.22e-01 81.1% 56.5%
5010738 101.1.2.30 alpha arrays › HTH › HTH › winged helix domain › TrmB 0.66 42.0 4.63e-01 78.3% 78.0%
4985036 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.65 43.0 4.06e-01 81.8% 55.9%
4001659 101.1.2.236 alpha arrays › HTH › HTH › winged helix domain › POLR3C_WHD 0.65 46.0 4.30e-01 83.9% 58.9%
4970576 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.65 46.0 4.22e-01 86.0% 57.2%
4561147 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.64 45.0 4.72e-01 83.2% 78.9%
4467359 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.64 44.0 4.20e-01 79.0% 59.4%
4585912 101.1.2.603 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9 0.63 52.0 3.76e-01 85.3% 64.5%
3468223 101.1.2.90 alpha arrays › HTH › HTH › winged helix domain › HTH_9 0.63 49.0 3.65e-01 81.1% 56.5%
5007541 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.62 41.0 4.71e-01 81.1% 90.5%
4965874 101.1.2.30 alpha arrays › HTH › HTH › winged helix domain › TrmB 0.61 41.0 4.21e-01 81.8% 70.9%
3306699 101.1.2.517 alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.60 46.0 3.35e-01 82.5% 29.6%
4999429 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.59 43.0 3.74e-01 75.5% 68.4%
4221024 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 43.0 3.86e-01 80.4% 65.4%
3262460 101.1.2.661 alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD 0.56 46.0 3.37e-01 86.0% 36.2%
D2 high residues 232-333
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.83 31.0 3.89e-01 85.3% 56.1%
1ulyA02 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.82 51.0 5.16e-01 75.5% 63.4%
3lynB00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.69 52.0 4.89e-01 80.4% 76.6%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.68 51.0 5.32e-01 78.4% 93.4%
5zjgA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.66 49.0 4.79e-01 78.4% 73.2%
6qs7C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 50.0 4.58e-01 80.4% 93.2%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 46.0 4.66e-01 74.5% 88.3%
4jd9G00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.64 45.0 4.25e-01 72.5% 60.0%
4q2cA01 1.10.3210.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › 0.64 49.0 3.58e-01 79.4% 93.9%
1gakA00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.64 49.0 4.50e-01 82.4% 74.5%
2pv4A00 1.10.3440.10 Mainly Alpha › Orthogonal Bundle › Sama2622-like fold › Sama2622-like 0.64 52.0 4.67e-01 90.2% 86.2%
4akgA06 1.10.8.710 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain 0.62 47.0 4.65e-01 80.4% 78.5%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 49.0 3.79e-01 84.3% 82.9%
4mcwA02 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.61 41.0 3.37e-01 77.5% 36.8%
2z3tA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 45.0 3.04e-01 80.4% 45.7%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.59 47.0 4.14e-01 87.3% 78.4%
3tjmA02 1.10.1470.20 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2 0.58 35.0 3.71e-01 84.3% 66.7%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.58 39.0 4.23e-01 70.6% 90.2%
1ic8A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 37.0 3.86e-01 76.5% 73.4%
2ahmG01 6.10.250.2820 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 38.0 3.88e-01 99.0% 71.7%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 44.0 3.32e-01 84.3% 76.9%
6b8hO01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.55 31.0 3.17e-01 80.4% 53.5%
4fm3A00 1.20.1270.390 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 43.0 4.48e-01 88.2% 90.5%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 42.0 4.27e-01 99.0% 83.0%
3cymA03 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.54 37.0 3.89e-01 81.4% 81.8%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 37.0 3.56e-01 70.6% 67.5%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 41.0 2.98e-01 80.4% 80.8%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.53 36.0 3.49e-01 71.6% 62.5%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.52 45.0 3.74e-01 95.1% 77.7%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 39.0 4.16e-01 78.4% 98.9%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 34.0 3.91e-01 71.6% 91.9%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 36.0 3.37e-01 73.5% 62.3%
2oocB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.50 36.0 3.63e-01 92.2% 73.3%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1299307 4230.1.1.4 alpha arrays › DnaD domain › DnaD domain › DnaD domain › Bac_RepA_C 0.81 71.0 6.88e-01 94.1% 87.5%
3177803 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.75 52.0 5.35e-01 77.5% 75.8%
3308688 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.72 51.0 5.82e-01 79.4% 100.0%
4671784 3755.3.1.310 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CemA 0.69 48.0 4.59e-01 71.6% 62.5%
5001008 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.69 53.0 4.14e-01 81.4% 84.7%
3590799 191.1.1.12 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_8 0.69 55.0 5.16e-01 86.3% 70.4%
3790645 5067.1.1.3 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched 0.67 56.0 4.72e-01 91.2% 67.1%
134276 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.65 46.0 4.66e-01 74.5% 88.3%
4033044 632.19.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.62 43.0 4.75e-01 72.5% 96.0%
4034551 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.62 45.0 3.21e-01 76.5% 31.4%
3289973 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.61 50.0 4.56e-01 88.2% 67.4%
3607324 102.1.3.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain 0.61 47.0 4.40e-01 83.3% 88.5%
4471275 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.59 47.0 3.37e-01 84.3% 33.1%
3271988 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.59 40.0 4.52e-01 87.3% 95.9%
4944965 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 51.0 3.94e-01 97.1% 80.0%
4142393 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 51.0 4.16e-01 96.1% 57.8%
4971768 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 51.0 4.08e-01 95.1% 53.7%
5058433 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.57 38.0 2.68e-01 72.5% 23.0%
4971727 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 50.0 4.02e-01 95.1% 52.8%
3863064 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 50.0 3.95e-01 96.1% 53.0%
4994873 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 3.95e-01 95.1% 54.2%
5069593 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 50.0 4.01e-01 98.0% 83.6%
3286925 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.55 42.0 3.99e-01 80.4% 100.0%
5047042 6155.1.1.24 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2085 0.55 45.0 4.25e-01 88.2% 74.2%
4938736 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 3.88e-01 94.1% 56.7%
4992943 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.54 45.0 4.34e-01 89.2% 91.3%
4976307 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 3.83e-01 96.1% 55.8%
3680262 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.54 45.0 4.26e-01 93.1% 87.2%
3231065 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.53 41.0 3.23e-01 85.3% 59.2%
4947170 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 3.76e-01 97.1% 52.3%
4283760 1203.1.2.7 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR 0.52 43.0 3.87e-01 88.2% 73.6%
3190870 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.38e-01 100.0% 64.4%
3597141 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.67e-01 98.0% 84.8%
3508893 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 45.0 3.58e-01 97.1% 48.4%
4927307 632.11.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DUF357 0.51 34.0 3.71e-01 70.6% 81.2%
4959130 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.51 33.0 3.88e-01 71.6% 95.7%
3669784 1079.1.1.12 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › GDT1 0.51 39.0 3.17e-01 84.3% 57.7%
3304034 5050.1.1.42 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › GDT1 0.51 39.0 3.18e-01 84.3% 58.1%
D3 medium residues 376-437
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3d5lA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.80 62.0 6.60e-01 100.0% 100.0%
3ecsC01 1.20.120.1070 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain 0.78 61.0 5.26e-01 87.1% 56.0%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 62.0 6.51e-01 100.0% 100.0%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.76 67.0 5.85e-01 100.0% 64.9%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.75 55.0 4.15e-01 77.4% 49.0%
1h3lB00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.75 52.0 4.88e-01 75.8% 59.0%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.73 53.0 4.06e-01 77.4% 54.9%
3dplC03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 60.0 5.47e-01 100.0% 68.7%
7ccmB01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.72 60.0 4.72e-01 98.4% 47.6%
2ajrA01 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.71 48.0 3.17e-01 75.8% 16.6%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.71 51.0 3.83e-01 75.8% 39.6%
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.71 62.0 5.33e-01 100.0% 94.1%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.70 55.0 4.21e-01 85.5% 87.9%
4ye6A02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.69 54.0 5.51e-01 91.9% 93.1%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.68 59.0 4.99e-01 100.0% 68.5%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.68 47.0 4.06e-01 75.8% 45.4%
3k40A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.68 61.0 3.93e-01 100.0% 64.9%
3k6hA01 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.66 49.0 3.61e-01 80.6% 85.6%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.65 52.0 4.51e-01 100.0% 55.2%
7p2yd01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.65 56.0 4.84e-01 100.0% 62.6%
2uuqA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.65 53.0 3.36e-01 100.0% 65.2%
2f48A03 1.10.10.480 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphofructokinase; domain 3 0.64 53.0 5.07e-01 96.8% 81.3%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.64 48.0 4.93e-01 96.8% 90.0%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.62 49.0 4.61e-01 91.9% 80.2%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 52.0 4.49e-01 98.4% 83.3%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 44.0 3.67e-01 79.0% 42.6%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.60 50.0 4.58e-01 93.5% 70.6%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 49.0 3.91e-01 100.0% 52.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 44.0 4.10e-01 82.3% 64.1%
4tvsA00 3.40.50.12190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 51.0 3.56e-01 100.0% 49.1%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.59 47.0 4.45e-01 91.9% 83.3%
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.59 48.0 4.38e-01 98.4% 73.3%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 45.0 3.85e-01 88.7% 90.9%
3urzA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 48.0 3.41e-01 95.2% 37.1%
2hydA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.57 43.0 2.83e-01 87.1% 52.3%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.57 41.0 3.90e-01 77.4% 89.2%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.57 48.0 3.55e-01 98.4% 62.9%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 45.0 3.86e-01 91.9% 76.6%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.56 48.0 4.39e-01 100.0% 84.7%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 46.0 3.75e-01 100.0% 48.5%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.55 45.0 4.08e-01 100.0% 79.2%
3tixB03 3.40.50.11490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 45.0 3.48e-01 93.5% 80.5%
4wbyA02 1.10.3090.10 Mainly Alpha › Orthogonal Bundle › cca-adding enzyme, domain 2 › cca-adding enzyme, domain 2 0.55 39.0 2.68e-01 75.8% 20.3%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.55 46.0 3.80e-01 95.2% 74.1%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.55 44.0 4.28e-01 96.8% 84.9%
3pieC01 3.40.50.12390 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 45.0 3.10e-01 100.0% 32.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 40.0 2.73e-01 82.3% 24.2%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 45.0 3.76e-01 96.8% 53.6%
3pubA01 1.10.10.2400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain 0.53 38.0 3.69e-01 95.2% 68.9%
2ii2A01 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.52 40.0 3.93e-01 95.2% 78.3%
2wapA00 3.90.1300.10 Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain 0.52 42.0 2.53e-01 98.4% 34.9%
3r0xA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 43.0 3.47e-01 93.5% 87.0%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 43.0 4.08e-01 100.0% 94.9%
2xppA00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.50 42.0 3.35e-01 98.4% 73.0%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3588971 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.81 57.0 5.38e-01 74.2% 64.0%
3726085 101.1.2.127 alpha arrays › HTH › HTH › winged helix domain › Cullin_Nedd8 0.80 63.0 5.74e-01 100.0% 63.5%
3970007 3502.1.1.0 alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein 0.80 55.0 5.20e-01 72.6% 60.0%
4543805 230.3.1.1 a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS 0.78 57.0 4.47e-01 77.4% 41.1%
5048577 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.77 66.0 6.09e-01 95.2% 86.3%
1068638 101.35.1.4 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.77 62.0 6.51e-01 100.0% 100.0%
4224925 4336.2.1.1 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › EnY2 0.76 56.0 4.93e-01 79.0% 58.9%
3452645 101.35.1.31 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Gliadin 0.76 65.0 5.68e-01 98.4% 68.4%
3479514 101.1.2.318 alpha arrays › HTH › HTH › winged helix domain › HSD3 0.75 63.0 6.10e-01 100.0% 84.3%
4995680 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.74 56.0 5.70e-01 96.8% 86.7%
3935995 101.1.2.127 alpha arrays › HTH › HTH › winged helix domain › Cullin_Nedd8 0.73 61.0 5.75e-01 100.0% 76.0%
5082325 3705.1.1.3 alpha arrays › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Bacterial chaperone lipoprotein (PulS_OutS) › Phage_holin_6_1 0.73 62.0 6.02e-01 98.4% 88.6%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 54.0 4.90e-01 80.6% 74.1%
3494078 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.73 60.0 6.01e-01 100.0% 90.8%
4934319 101.1.2.947 alpha arrays › HTH › HTH › winged helix domain › PF27234 0.72 57.0 5.76e-01 100.0% 87.3%
3869172 5000.3.1.0 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death 0.72 61.0 4.60e-01 98.4% 43.8%
4962283 604.4.1.0 alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP 0.72 63.0 5.82e-01 100.0% 88.7%
3588902 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.71 63.0 4.84e-01 100.0% 78.6%
3209632 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.70 62.0 5.14e-01 100.0% 83.6%
3877844 529.1.1.2 few secondary structure elements › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › BSMAP 0.70 61.0 5.44e-01 100.0% 67.8%
4624818 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.70 61.0 5.42e-01 100.0% 83.3%
4973291 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.70 60.0 5.61e-01 100.0% 77.5%
4029043 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.69 57.0 5.15e-01 96.8% 83.3%
3939789 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.68 58.0 5.26e-01 98.4% 71.8%
3578362 101.1.1.4 alpha arrays › HTH › HTH › Three-helical HTH › PAX 0.67 50.0 4.74e-01 96.8% 68.0%
3792916 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.66 55.0 5.21e-01 93.5% 84.0%
3560358 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.66 48.0 3.70e-01 83.9% 33.8%
3510771 610.4.1.0 alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain 0.65 53.0 4.63e-01 98.4% 59.0%
3789626 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 49.0 4.87e-01 98.4% 80.0%
5022724 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 54.0 5.14e-01 98.4% 89.3%
3657981 198.1.1.16 alpha arrays › Saposin-like › Saposin-like › Saposin-like › HTH_70 0.64 55.0 5.10e-01 100.0% 80.0%
5025586 101.1.6.0 alpha arrays › HTH › HTH › TrpR 0.64 52.0 4.92e-01 90.3% 96.0%
4136793 2006.1.4.4 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N 0.64 51.0 3.55e-01 88.7% 53.3%
4327215 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.64 45.0 3.80e-01 77.4% 45.2%
4469265 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.64 53.0 3.89e-01 100.0% 34.1%
4176201 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.63 54.0 4.77e-01 100.0% 84.2%
4980095 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.63 51.0 4.44e-01 96.8% 84.8%
4993526 101.11.1.13 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › EMC6_arch 0.62 52.0 4.76e-01 100.0% 83.0%
5047035 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.62 42.0 4.25e-01 71.0% 75.0%
5005257 2.21.1.0 beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.61 51.0 3.87e-01 100.0% 52.4%
5025218 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 45.0 2.90e-01 98.4% 13.9%
169082 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.60 48.0 3.39e-01 95.2% 27.5%
5063791 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.59 48.0 3.12e-01 98.4% 84.5%
4091671 3684.1.1.1 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF615 0.57 40.0 3.81e-01 77.4% 96.2%
3237364 2004.1.1.24 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C 0.56 46.0 2.68e-01 100.0% 38.1%
3610233 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 46.0 3.79e-01 96.8% 72.8%
5060846 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 43.0 4.06e-01 90.3% 74.7%
2142296 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.52 41.0 3.62e-01 91.9% 70.4%
3732491 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 40.0 3.25e-01 96.8% 43.2%