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KU530220.1__AMD42817.1__SEA_XKCD426_76__00076

Bact-Vir

KU530220.1__AMD42817.1__SEA_XKCD426_76__00076

Identity

Accession:
KU530220 ↗
Kingdom:
phage

Quality

75.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-132
PDB
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 64.0 5.56e-01 96.0% 92.1%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 52.0 5.69e-01 74.4% 100.0%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.71 61.0 6.32e-01 93.6% 100.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.71 55.0 5.65e-01 80.0% 97.4%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 45.0 3.60e-01 100.0% 34.9%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 45.0 3.44e-01 100.0% 30.2%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 51.0 5.03e-01 76.8% 96.2%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 63.0 5.24e-01 99.2% 64.2%
5mawD00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.69 48.0 3.75e-01 72.0% 52.3%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 61.0 5.17e-01 96.8% 73.5%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 48.0 4.82e-01 72.8% 73.8%
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 60.0 5.84e-01 96.8% 89.9%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.67 45.0 5.24e-01 71.2% 97.7%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.66 49.0 4.02e-01 76.8% 53.5%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.66 45.0 4.53e-01 91.2% 68.5%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.66 54.0 4.60e-01 88.0% 72.0%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 47.0 4.83e-01 75.2% 96.7%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 44.0 4.59e-01 70.4% 77.8%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 51.0 5.03e-01 85.6% 81.6%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.64 41.0 4.07e-01 75.2% 60.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.64 52.0 5.41e-01 88.0% 97.4%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 46.0 5.03e-01 75.2% 94.1%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 55.0 5.63e-01 96.0% 100.0%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 48.0 5.22e-01 89.6% 100.0%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.63 46.0 4.22e-01 75.2% 80.4%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 46.0 4.52e-01 75.2% 77.6%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 45.0 4.83e-01 75.2% 99.1%
3b9wA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.62 47.0 3.40e-01 80.0% 81.2%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 47.0 5.15e-01 89.6% 100.0%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 53.0 4.94e-01 92.0% 100.0%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 53.0 4.90e-01 96.0% 74.1%
4l6rA02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 52.0 3.94e-01 90.4% 83.6%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 45.0 3.67e-01 100.0% 43.3%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 43.0 4.64e-01 72.0% 95.1%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.61 43.0 4.58e-01 72.8% 96.4%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.61 52.0 5.09e-01 100.0% 85.1%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.61 51.0 3.78e-01 92.0% 95.8%
1f7uA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 43.0 4.37e-01 82.4% 74.4%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 49.0 4.62e-01 87.2% 100.0%
3o7qA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.60 53.0 4.63e-01 99.2% 94.8%
3uonA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 47.0 3.71e-01 88.8% 91.8%
3m6jA01 1.20.1260.40 Mainly Alpha › Up-down Bundle › Ferritin › 0.58 43.0 4.41e-01 87.2% 82.1%
3on2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 41.0 3.58e-01 72.8% 50.0%
6k41R00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 46.0 3.79e-01 87.2% 90.5%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 51.0 4.80e-01 98.4% 80.1%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.57 51.0 4.30e-01 100.0% 97.7%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.57 36.0 3.81e-01 85.6% 71.3%
3etvA01 1.10.287.3290 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 37.0 4.38e-01 72.8% 100.0%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 43.0 4.72e-01 85.6% 100.0%
2q58B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 51.0 3.70e-01 98.4% 54.4%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.56 48.0 4.28e-01 93.6% 71.7%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.55 48.0 4.74e-01 91.2% 88.5%
3dpjF00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 40.0 3.59e-01 76.8% 77.1%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 44.0 4.39e-01 87.2% 99.3%
4hfvA01 1.20.1440.330 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.55 41.0 4.21e-01 78.4% 87.2%
1wvtA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.54 44.0 4.21e-01 100.0% 76.4%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 45.0 4.00e-01 99.2% 62.2%
3snhA02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.53 40.0 3.38e-01 79.2% 59.7%
8i3jA01 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.53 48.0 3.84e-01 100.0% 61.0%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 44.0 4.17e-01 90.4% 75.3%
6ko5A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 47.0 3.60e-01 100.0% 61.3%
3b5oA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 46.0 3.84e-01 100.0% 56.5%
4mo1A00 1.10.274.110 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › 0.52 42.0 4.04e-01 87.2% 92.4%
2cfqA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 45.0 3.85e-01 96.8% 92.9%
4i8qA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 40.0 3.07e-01 81.6% 45.7%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.50 36.0 3.42e-01 78.4% 59.6%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3279601 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.83 77.0 6.90e-01 100.0% 82.4%
4345163 633.10.1.28 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › PF27080 0.77 66.0 6.83e-01 90.4% 100.0%
4178099 632.22.1.176 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF27734 0.73 42.0 3.96e-01 100.0% 46.5%
3186867 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 43.0 3.86e-01 100.0% 44.8%
3287135 6164.1.1.2 alpha bundles › Bestrophin › Bestrophin › Bestrophin › DUF4239 0.71 65.0 5.12e-01 100.0% 67.2%
3701078 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 62.0 6.12e-01 97.6% 95.6%
4967572 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.70 63.0 5.39e-01 98.4% 64.5%
3518770 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 51.0 4.58e-01 75.2% 75.9%
3276862 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.69 62.0 5.22e-01 100.0% 90.7%
3263668 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 53.0 5.69e-01 90.4% 98.1%
3830361 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 60.0 5.65e-01 100.0% 79.4%
3248267 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 59.0 5.70e-01 96.8% 97.9%
3712159 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 61.0 5.74e-01 100.0% 83.9%
3494868 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.68 61.0 5.04e-01 100.0% 56.3%
3739779 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 45.0 3.85e-01 100.0% 45.4%
4985462 192.2.1.89 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF7121 0.67 60.0 4.82e-01 100.0% 50.8%
3590532 1075.1.2.13 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › CNNM 0.66 46.0 4.21e-01 71.2% 79.4%
4027849 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.66 60.0 4.94e-01 100.0% 95.2%
3976441 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.66 56.0 5.69e-01 92.8% 96.0%
3247352 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 56.0 5.65e-01 93.6% 96.8%
3918141 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.65 56.0 5.61e-01 94.4% 95.4%
3828970 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.65 47.0 5.33e-01 76.0% 100.0%
3304219 109.3.1.181 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Serinc 0.65 45.0 4.13e-01 74.4% 55.0%
3919997 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.64 56.0 5.69e-01 96.8% 98.3%
3720809 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.64 47.0 4.65e-01 76.0% 79.2%
3304829 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 56.0 5.08e-01 98.4% 79.2%
4137366 109.3.1.181 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Serinc 0.63 45.0 4.17e-01 74.4% 57.5%
3739903 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 55.0 5.16e-01 100.0% 89.4%
3488589 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 55.0 4.50e-01 100.0% 88.8%
3616490 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.62 55.0 5.21e-01 98.4% 98.7%
3485310 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.62 55.0 5.30e-01 99.2% 100.0%
3413600 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 55.0 5.49e-01 99.2% 96.2%
3399286 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.61 52.0 5.38e-01 92.0% 100.0%
3736269 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 55.0 4.50e-01 100.0% 80.9%
5031795 109.3.1.483 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF2070 0.60 50.0 4.01e-01 90.4% 47.4%
3851222 304.28.1.34 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL, Sterol-sensing 0.59 51.0 3.10e-01 94.4% 46.6%
3964011 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.59 48.0 5.05e-01 87.2% 100.0%
4944890 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 52.0 4.49e-01 97.6% 95.5%
3589249 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.59 53.0 4.34e-01 100.0% 93.6%
3278319 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 52.0 3.63e-01 100.0% 44.4%
3289801 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 53.0 4.41e-01 99.2% 58.1%
3949475 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.59 50.0 4.27e-01 95.2% 93.3%
2329732 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.58 45.0 4.27e-01 89.6% 69.4%
3289339 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 51.0 4.40e-01 99.2% 61.5%
5018146 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.58 43.0 3.52e-01 78.4% 97.9%
3388359 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 51.0 4.39e-01 100.0% 93.0%
3289514 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.57 45.0 3.54e-01 84.8% 85.2%
4262528 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 50.0 4.31e-01 100.0% 92.7%
3723111 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.56 51.0 4.05e-01 100.0% 77.6%
3403601 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.23e-01 95.2% 94.9%
3693444 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.56 50.0 4.56e-01 100.0% 82.9%
5055517 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.56 45.0 4.37e-01 88.0% 87.9%
4933633 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 49.0 4.30e-01 99.2% 94.7%
3634099 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 49.0 3.98e-01 100.0% 80.0%
3205832 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 49.0 3.98e-01 100.0% 82.0%
4448955 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.55 42.0 2.87e-01 100.0% 24.3%
4997244 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 49.0 4.14e-01 100.0% 61.0%
3781957 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.54 46.0 3.83e-01 92.0% 63.3%
4140346 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 3.13e-01 100.0% 42.9%
3696811 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.53 47.0 4.53e-01 99.2% 87.6%
5050120 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.53 44.0 3.93e-01 90.4% 73.2%
4213060 5050.1.1.3 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › LacY_symp 0.53 47.0 4.01e-01 100.0% 91.9%
4003422 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.53 47.0 4.30e-01 100.0% 84.2%
4145540 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 47.0 4.38e-01 100.0% 80.0%
4226581 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 47.0 3.99e-01 100.0% 61.9%
4012651 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 46.0 4.16e-01 100.0% 80.0%
4927302 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.51 40.0 3.86e-01 83.2% 81.4%
3314927 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.51 42.0 3.82e-01 88.8% 66.7%
3358852 3755.4.1.62 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF31016 0.51 44.0 4.06e-01 100.0% 74.2%
4523046 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.51 37.0 3.63e-01 100.0% 70.4%
4000733 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.50 44.0 4.37e-01 96.0% 93.8%
4997684 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.50 38.0 2.89e-01 80.0% 60.5%
D2 medium residues 136-203
PDB
Domain cluster: representative
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.79 57.0 4.58e-01 76.5% 54.7%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 53.0 4.76e-01 70.6% 52.7%
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.77 53.0 4.16e-01 72.1% 36.7%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.75 53.0 4.90e-01 73.5% 68.2%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.72 51.0 4.33e-01 76.5% 62.9%
1eteA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.71 49.0 3.87e-01 70.6% 62.7%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.70 46.0 4.98e-01 73.5% 80.7%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 49.0 4.24e-01 75.0% 52.4%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.69 51.0 4.20e-01 77.9% 47.1%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 50.0 4.86e-01 79.4% 71.4%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.64 46.0 4.47e-01 77.9% 68.8%
7e9uA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.62 48.0 2.93e-01 83.8% 38.7%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.62 45.0 3.98e-01 79.4% 54.7%
3fmsA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.60 47.0 3.78e-01 88.2% 70.9%
8amzT01 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 48.0 3.37e-01 98.5% 54.9%
1z5zA02 1.20.120.850 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain 0.57 41.0 4.02e-01 76.5% 92.1%
2psmA00 1.20.1250.70 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 0.56 45.0 3.82e-01 89.7% 79.5%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.56 41.0 3.46e-01 77.9% 82.2%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 40.0 3.28e-01 89.7% 72.9%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4968652 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.82 56.0 4.85e-01 70.6% 51.0%
3708191 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 52.0 5.03e-01 70.6% 66.7%
3267859 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.75 54.0 4.94e-01 79.4% 57.8%
3608758 604.12.1.8 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.75 55.0 5.21e-01 77.9% 70.0%
3788338 604.12.1.9 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 0.74 54.0 5.31e-01 77.9% 77.0%
3250840 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 48.0 4.59e-01 83.8% 81.0%
5063219 109.25.1.15 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › Cpn60_TCP1 0.56 47.0 3.81e-01 97.1% 84.8%
D3 medium residues 270-336
PDB
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF12728.14 best HTH_17 33.6 5.50e-08 71.6% 88.2%
PF13411.13 MerR_1 30.2 5.60e-07 71.6% 65.2%
PF08281.19 Sigma70_r4_2 26.5 5.70e-06 46.3% 50.0%