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KX119197.1__ANT42939.1__X__00015

Bact-Vir

KX119197.1__ANT42939.1__X__00015

Identity

Accession:
KX119197 ↗
Kingdom:
phage

Quality

71.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 275-349
PDB
D2 high residues 1161-1309
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF18763.8 best ddrB-ParB 108.4 3.70e-31 75.2% 98.4%
D3 medium residues 189-274
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mynA00 3.30.30.10 Alpha Beta › 2-Layer Sandwich › Defensin A-like › Knottin, scorpion toxin-like 0.64 34.0 4.39e-01 77.9% 100.0%
4u1cA01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.63 35.0 4.38e-01 79.1% 90.4%
1n4nA00 3.30.30.10 Alpha Beta › 2-Layer Sandwich › Defensin A-like › Knottin, scorpion toxin-like 0.63 34.0 4.29e-01 76.7% 95.7%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.61 40.0 3.06e-01 87.2% 29.0%
1dbzA01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.60 51.0 4.11e-01 100.0% 86.4%
3auxA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 46.0 3.06e-01 82.6% 56.3%
2hzmG01 3.30.310.180 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.58 43.0 3.98e-01 80.2% 91.3%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 43.0 3.82e-01 80.2% 88.7%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.57 43.0 4.44e-01 81.4% 96.4%
3kihC01 2.20.25.510 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.56 24.0 3.19e-01 80.2% 85.3%
1yy7A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 41.0 3.89e-01 79.1% 88.6%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.55 41.0 3.72e-01 79.1% 83.8%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.55 46.0 4.37e-01 90.7% 85.0%
3hj4A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.54 43.0 3.83e-01 89.5% 84.7%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.54 44.0 4.01e-01 88.4% 89.4%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.54 41.0 3.88e-01 81.4% 96.1%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.53 48.0 4.31e-01 100.0% 100.0%
1fnoA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.53 43.0 3.11e-01 95.3% 94.6%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.53 40.0 3.17e-01 82.6% 83.9%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 38.0 2.79e-01 76.7% 81.5%
4aidA02 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.52 39.0 4.05e-01 87.2% 86.6%
4g10A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 41.0 3.53e-01 86.0% 55.9%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.51 41.0 3.66e-01 88.4% 89.9%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.51 42.0 3.39e-01 91.9% 89.1%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 38.0 3.03e-01 81.4% 75.3%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3679879 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 42.0 4.17e-01 70.9% 62.2%
3682372 109.4.1.1361 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CAND1 0.63 44.0 3.47e-01 72.1% 78.9%
4996227 873.1.1.1 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › V4R 0.63 45.0 3.81e-01 76.7% 61.3%
4278911 4.8.1.5 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › LytTR 0.62 30.0 3.87e-01 88.4% 82.0%
4112791 4.8.1.5 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › LytTR 0.59 30.0 3.75e-01 88.4% 82.0%
5011998 2004.1.1.308 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.59 46.0 3.12e-01 84.9% 39.1%
1251943 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.59 45.0 3.97e-01 81.4% 87.2%
3801665 4040.1.1.1 alpha bundles › Fic-like › Fic-like › Fic-like › Fic 0.58 42.0 3.90e-01 75.6% 78.2%
3923954 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.56 43.0 3.70e-01 81.4% 78.5%
1780951 2004.1.1.514 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_29, SbcC_Walker_B 0.56 42.0 2.81e-01 80.2% 56.3%
3597100 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 41.0 3.36e-01 76.7% 57.1%
3593059 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.56 43.0 3.79e-01 86.0% 76.3%
4469629 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.55 40.0 3.28e-01 76.7% 76.4%
3971908 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.55 46.0 4.09e-01 91.9% 78.4%
3488338 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.54 45.0 3.79e-01 91.9% 89.3%
3604350 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 44.0 3.93e-01 87.2% 73.3%
3253929 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.54 44.0 3.92e-01 87.2% 89.2%
3580283 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 37.0 3.77e-01 70.9% 89.4%
3420616 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.54 44.0 3.24e-01 89.5% 78.9%
3260290 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.53 38.0 2.83e-01 74.4% 64.2%
4949854 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.53 41.0 3.76e-01 82.6% 77.9%
3765475 101.1.2.69 alpha arrays › HTH › HTH › winged helix domain › La 0.53 40.0 3.80e-01 91.9% 69.0%
3221738 192.29.1.172 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.52 39.0 3.36e-01 81.4% 86.4%
5075529 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.51 40.0 3.50e-01 82.6% 93.8%
4594071 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.50 39.0 3.94e-01 87.2% 84.7%
3510175 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.50 38.0 3.30e-01 80.2% 97.7%
3813753 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.50 42.0 3.57e-01 90.7% 84.3%
3838381 2004.1.1.308 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.50 44.0 2.95e-01 98.8% 37.0%
D4 medium residues 526-693
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.79 26.0 4.68e-01 94.0% 100.0%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.75 31.0 3.80e-01 96.4% 58.7%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.73 26.0 4.38e-01 98.8% 91.8%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.71 33.0 3.44e-01 100.0% 47.7%
5fmnA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.67 28.0 3.82e-01 96.4% 74.4%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.66 37.0 4.00e-01 83.3% 62.6%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.64 36.0 4.59e-01 75.6% 93.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.61 33.0 3.44e-01 100.0% 55.3%
1yowA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.61 39.0 3.55e-01 99.4% 46.1%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 33.0 3.86e-01 73.8% 73.9%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 32.0 4.00e-01 81.0% 84.2%
4n1yB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.60 38.0 3.49e-01 99.4% 47.1%
1pduA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.59 37.0 3.37e-01 99.4% 44.3%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 34.0 3.83e-01 97.0% 71.4%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.58 43.0 4.12e-01 76.8% 94.4%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 36.0 4.37e-01 81.0% 93.8%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 32.0 2.96e-01 100.0% 43.1%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.57 43.0 3.98e-01 77.4% 86.8%
1za0A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.57 40.0 3.59e-01 72.6% 99.2%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 31.0 2.88e-01 100.0% 42.1%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 29.0 2.63e-01 98.8% 35.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 37.0 4.32e-01 81.0% 94.0%
2j1oA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 44.0 3.86e-01 82.7% 78.8%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 46.0 4.83e-01 90.5% 99.3%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 33.0 3.73e-01 79.8% 80.5%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 42.0 2.86e-01 84.5% 73.7%
1h0oA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.52 39.0 3.36e-01 79.2% 99.0%
1k74D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 34.0 2.95e-01 99.4% 40.1%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.52 32.0 4.05e-01 99.4% 99.0%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.50 41.0 3.94e-01 96.4% 75.7%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4112797 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 33.0 3.11e-01 100.0% 36.4%
5010596 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 34.0 3.09e-01 100.0% 34.5%
3711643 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.68 33.0 2.77e-01 100.0% 28.7%
3486193 188.1.1.0 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain 0.67 42.0 3.75e-01 100.0% 42.9%
3385717 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 33.0 3.31e-01 100.0% 46.5%
3577907 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.65 34.0 2.89e-01 100.0% 32.9%
3998922 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.63 50.0 4.03e-01 82.7% 92.2%
3395071 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.63 40.0 3.55e-01 100.0% 42.9%
3703191 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.61 29.0 3.76e-01 95.2% 76.0%
4956930 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 39.0 3.40e-01 100.0% 43.8%
3921009 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 32.0 2.37e-01 75.6% 19.5%
3928215 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.60 44.0 4.26e-01 75.0% 95.8%
3386594 3291.1.1.197 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MCPsignal 0.60 31.0 3.94e-01 98.8% 81.9%
4964135 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.59 33.0 4.11e-01 79.8% 89.0%
4555698 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.58 39.0 3.35e-01 100.0% 43.0%
4246492 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.58 31.0 4.02e-01 78.6% 91.6%
3929613 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 32.0 2.60e-01 100.0% 29.8%
5059032 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.57 39.0 3.78e-01 70.2% 95.4%
3729252 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 35.0 4.30e-01 73.8% 97.4%
3347262 109.4.1.1242 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_RRP12_N 0.54 39.0 3.29e-01 74.4% 77.1%
3309205 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.53 43.0 4.61e-01 100.0% 99.3%
3741922 109.4.1.335 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N 0.53 41.0 3.50e-01 79.8% 65.8%
3554564 5050.1.1.4 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran 0.53 43.0 3.79e-01 86.3% 76.7%
4600042 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 42.0 3.85e-01 83.9% 74.0%
3722750 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.51 39.0 3.15e-01 78.6% 76.9%
3423437 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 39.0 3.94e-01 78.0% 88.5%
3696717 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 40.0 3.86e-01 82.7% 94.2%
3834205 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.50 38.0 3.87e-01 78.6% 83.6%
D5 medium residues 694-769_878-900
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3hhgE01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 37.0 3.94e-01 74.7% 64.8%
1aowA02 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.60 36.0 4.06e-01 76.8% 79.7%
3himA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 40.0 3.29e-01 72.7% 52.1%
1xeqB00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.57 33.0 3.56e-01 70.7% 67.1%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 38.0 3.22e-01 71.7% 56.6%
2qenA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 32.0 3.61e-01 73.7% 82.9%
4r0zA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.53 38.0 2.43e-01 76.8% 32.0%
4jvyB00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.52 38.0 3.08e-01 75.8% 96.8%
3zheA02 1.25.40.760 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 42.0 3.42e-01 90.9% 77.3%
3hn2A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 38.0 3.48e-01 76.8% 92.2%
4r8zA00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.51 37.0 2.90e-01 76.8% 44.5%
2dk8A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 31.0 3.59e-01 73.7% 92.3%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4370821 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.60 33.0 3.57e-01 75.8% 61.2%
3693702 101.1.2.384 alpha arrays › HTH › HTH › winged helix domain › Myb_DNA-bind_8 0.59 34.0 4.18e-01 72.7% 93.3%
3223911 2003.1.1.155 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3HCDH_N, F420_oxidored 0.57 40.0 3.17e-01 85.9% 36.0%
3560929 148.1.3.19 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.57 39.0 3.95e-01 72.7% 71.0%
5050809 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 42.0 2.88e-01 79.8% 90.4%
3704736 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 40.0 2.65e-01 76.8% 38.6%
3589725 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 34.0 3.90e-01 73.7% 91.4%
4104199 3018.1.1.1 a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS 0.52 33.0 3.40e-01 75.8% 66.3%
3803063 109.4.1.238 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP_TPR_like 0.52 39.0 2.65e-01 78.8% 27.7%
4015713 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 38.0 2.78e-01 76.8% 64.0%
3594525 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.51 37.0 3.72e-01 75.8% 88.0%
3250585 109.4.1.791 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.51 37.0 2.35e-01 76.8% 22.3%
D6 medium residues 916-1062
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF18809.7 best PBECR1 73.8 2.00e-20 73.5% 98.1%
PF12033.14 DUF3519 39.8 6.60e-10 35.4% 43.3%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2kheA00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.62 37.0 4.59e-01 97.3% 96.6%
5tw4A02 2.30.140.20 Mainly Beta › Roll › Spermidine Synthase; Chain: A, domain 2 › Penicillin-binding protein 4, C-terminal domain 0.52 21.0 2.85e-01 80.3% 69.6%
1y9lA00 2.40.128.230 Mainly Beta › Beta Barrel › Lipocalin › Pilot protein MxiM 0.52 30.0 3.42e-01 93.2% 75.5%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3839082 4312.1.1.20 a+b two layers › RelE-like › RelE-like › RelE-like › DUF3519, PBECR1 0.97 87.0 9.10e-01 95.9% 100.0%
5080427 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.68 38.0 4.95e-01 97.3% 100.0%
5042309 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.68 38.0 4.72e-01 96.6% 88.9%
4941220 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.67 38.0 4.92e-01 98.6% 100.0%
5007064 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.66 35.0 4.75e-01 70.1% 100.0%
3955817 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.66 41.0 4.88e-01 87.8% 92.9%
4928181 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.65 36.0 4.64e-01 97.3% 94.1%
4968316 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.64 37.0 4.66e-01 98.0% 95.5%
3945861 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.63 37.0 4.54e-01 74.1% 92.2%
5071213 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.63 35.0 4.56e-01 95.9% 100.0%
5014619 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.62 35.0 4.51e-01 96.6% 100.0%
3806421 247.1.1.38 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C 0.62 22.0 3.26e-01 95.2% 70.8%
4984297 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.59 35.0 4.20e-01 87.8% 93.3%
5018720 4312.1.1.3 a+b two layers › RelE-like › RelE-like › RelE-like › ParE_toxin 0.59 35.0 4.28e-01 87.8% 98.8%
3989328 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.55 35.0 4.23e-01 99.3% 98.9%
3577380 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.55 26.0 3.59e-01 83.0% 92.9%
3507907 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.54 27.0 2.89e-01 76.2% 53.6%
3732152 331.1.1.5 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › OGG_N 0.54 24.0 3.07e-01 74.8% 70.0%
3520092 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.53 25.0 3.26e-01 83.0% 78.8%
5053646 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.53 24.0 3.05e-01 97.3% 69.4%
3307575 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.52 26.0 3.08e-01 78.2% 68.0%
4000819 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.51 23.0 3.19e-01 81.0% 85.7%
3409941 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.50 25.0 3.36e-01 83.0% 95.7%
D7 medium residues 1311-1401
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.57 39.0 3.96e-01 70.3% 87.8%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 40.0 3.57e-01 74.7% 90.6%
3djbA01 1.10.472.50 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like 0.53 35.0 3.46e-01 71.4% 62.5%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.53 36.0 3.14e-01 70.3% 86.5%
2klqA00 1.20.58.870 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 39.0 3.66e-01 81.3% 95.6%
1f81A00 1.20.1020.10 Mainly Alpha › Up-down Bundle › CREB-binding Protein; Chain A › TAZ domain 0.51 32.0 3.32e-01 89.0% 65.5%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.51 38.0 3.09e-01 80.2% 75.7%
1e3pA02 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.50 35.0 3.71e-01 72.5% 86.7%
4tvvC00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.50 40.0 2.92e-01 89.0% 72.9%
3e0zA00 1.20.58.1400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Domain of unknown function DUF3837 0.50 35.0 3.37e-01 72.5% 95.3%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3439293 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.56 48.0 3.99e-01 95.6% 64.2%
4180109 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.55 39.0 3.92e-01 73.6% 81.1%
3657981 198.1.1.16 alpha arrays › Saposin-like › Saposin-like › Saposin-like › HTH_70 0.53 39.0 4.08e-01 76.9% 87.5%
5021927 101.1.1.550 alpha arrays › HTH › HTH › Three-helical HTH › DUF1016_N 0.53 45.0 4.15e-01 98.9% 89.6%
3744215 627.1.1.1 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 0.52 42.0 3.63e-01 87.9% 83.4%
D8 medium residues 1402-1584
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.61 32.0 3.92e-01 77.6% 78.6%
3x3bA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 34.0 3.03e-01 76.0% 36.9%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.58 33.0 3.62e-01 72.7% 66.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 28.0 3.39e-01 72.7% 68.5%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.56 35.0 4.11e-01 72.7% 89.0%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.55 35.0 4.19e-01 96.7% 99.1%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.55 39.0 3.79e-01 72.7% 83.7%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 35.0 3.98e-01 96.7% 85.6%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 30.0 3.38e-01 71.0% 69.4%
8st7C01 1.10.4140.10 Mainly Alpha › Orthogonal Bundle › effector protein (NleL) fold › effector protein (NleL) 0.53 32.0 3.08e-01 88.5% 51.0%
4jgwA02 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.52 32.0 2.91e-01 80.9% 45.4%
1y8aA02 1.10.3870.10 Mainly Alpha › Orthogonal Bundle › AF1437-like domain fold › AF1437-like domain superfamily 0.52 30.0 3.61e-01 91.8% 87.1%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 33.0 3.39e-01 85.8% 66.3%
4o6mA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.51 43.0 4.21e-01 89.1% 86.2%
3k7dA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.50 36.0 3.25e-01 71.6% 64.8%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3279521 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.58 46.0 4.57e-01 82.5% 94.2%
4961014 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 42.0 4.05e-01 77.0% 77.9%
4557092 633.23.1.32 alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.55 34.0 3.75e-01 76.5% 75.7%
5077948 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 39.0 3.86e-01 72.1% 81.6%
3910344 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 44.0 3.32e-01 85.8% 96.2%
5051571 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 38.0 3.81e-01 72.1% 78.5%
3692841 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 40.0 3.56e-01 77.6% 61.9%
3994626 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 37.0 3.52e-01 71.6% 70.9%
3632884 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 37.0 3.58e-01 71.0% 78.5%
3604551 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.52 38.0 3.97e-01 97.8% 81.2%
3415702 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 37.0 3.56e-01 72.7% 75.8%
4981180 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 38.0 3.84e-01 76.0% 81.6%
5051368 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.51 42.0 4.09e-01 85.2% 84.0%
4032837 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 36.0 3.64e-01 71.6% 82.2%
3969642 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 38.0 3.67e-01 75.4% 81.5%
3220780 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 40.0 3.71e-01 82.0% 80.0%
4031364 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 36.0 3.58e-01 72.7% 81.0%
3602104 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 36.0 3.50e-01 71.6% 78.5%
3179160 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 36.0 3.47e-01 71.6% 78.5%
3922622 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 38.0 3.49e-01 77.6% 77.9%
4014742 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.50 36.0 2.68e-01 73.8% 79.6%