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KX130960.1__APU93223.1__X__00023
Bact-VirKX130960.1__APU93223.1__X__00023
Identity
- Accession:
- KX130960 ↗
- Kingdom:
- phage
Quality
81.1
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Drexlerviridae›
Rtpvirus›
Escherichia_phage_vB_EcoS-IME253
TaxID: 1933412
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-54
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 49.0 | 3.72e-01 | 100.0% | 33.1% |
| 2d54A02 | 2.170.220.10 | Mainly Beta › Beta Complex › Methionyl-trna Synthetase; domain 2 › | 0.62 | 44.0 | 3.52e-01 | 98.0% | 34.2% |
| 4ie5A02 | 1.20.58.1470 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain | 0.62 | 54.0 | 3.96e-01 | 100.0% | 43.3% |
| 2wa0A02 | 1.10.10.1210 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MAGE homology domain, winged helix WH2 motif | 0.61 | 47.0 | 3.74e-01 | 89.8% | 79.6% |
| 5gj7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 47.0 | 3.56e-01 | 100.0% | 47.0% |
| 4by6D02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 52.0 | 3.36e-01 | 100.0% | 21.8% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 50.0 | 3.98e-01 | 100.0% | 49.1% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.59 | 47.0 | 3.84e-01 | 95.9% | 100.0% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 47.0 | 3.76e-01 | 95.9% | 97.2% |
| 3if2A00 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.58 | 43.0 | 2.52e-01 | 81.6% | 59.7% |
| 4inaA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.57 | 45.0 | 3.16e-01 | 98.0% | 43.1% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 47.0 | 3.17e-01 | 100.0% | 33.5% |
| 1bjaA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.57 | 46.0 | 3.78e-01 | 93.9% | 86.3% |
| 3fxqB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 44.0 | 3.80e-01 | 95.9% | 84.4% |
| 3szpA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 44.0 | 3.68e-01 | 93.9% | 49.4% |
| 1w07A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 45.0 | 3.16e-01 | 95.9% | 27.4% |
| 2q1fA02 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.55 | 46.0 | 2.76e-01 | 100.0% | 12.7% |
| 1a52A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.55 | 47.0 | 2.99e-01 | 98.0% | 56.1% |
| 3r4iA02 | 6.10.140.960 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 44.0 | 4.24e-01 | 95.9% | 78.3% |
| 4q7fA02 | 3.90.780.10 | Alpha Beta › Alpha-Beta Complex › 5'-nucleotidase; domain 2 › 5'-Nucleotidase, C-terminal domain | 0.54 | 42.0 | 2.86e-01 | 100.0% | 21.6% |
| 1pjqA02 | 3.30.160.110 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Sirohaem synthase, central domain | 0.54 | 31.0 | 3.49e-01 | 83.7% | 72.2% |
| 6guvA00 | 3.30.710.10 | Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A | 0.54 | 43.0 | 3.17e-01 | 89.8% | 55.2% |
| 2qvwD02 | 2.170.260.10 | Mainly Beta › Beta Complex › paz domain › paz domain | 0.53 | 41.0 | 3.27e-01 | 87.8% | 62.7% |
| 2fnaA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 42.0 | 2.80e-01 | 87.8% | 21.7% |
| 3cqxC00 | 1.20.58.890 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 42.0 | 3.70e-01 | 100.0% | 77.8% |
| 4l80D00 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.51 | 42.0 | 2.61e-01 | 100.0% | 15.1% |
| 1r7jA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 39.0 | 3.22e-01 | 91.8% | 45.6% |
| 1r6zA03 | 2.170.260.10 | Mainly Beta › Beta Complex › paz domain › paz domain | 0.50 | 39.0 | 3.00e-01 | 89.8% | 69.8% |
ECOD (53)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4374689 | 601.7.1.40 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas13a_C | 0.67 | 54.0 | 3.09e-01 | 93.9% | 20.9% |
| 5045159 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.66 | 56.0 | 3.46e-01 | 100.0% | 53.0% |
| 4408940 | 3265.1.1.1 ↗ | alpha arrays › C-terminal helical domain in tRNA modifying enzyme GidA › C-terminal helical domain in tRNA modifying enzyme GidA › C-terminal helical domain in tRNA modifying enzyme GidA › GIDA_C_1st | 0.65 | 49.0 | 4.31e-01 | 83.7% | 88.0% |
| 3463739 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.63 | 53.0 | 3.86e-01 | 100.0% | 32.7% |
| 3586666 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.62 | 48.0 | 3.18e-01 | 87.8% | 21.9% |
| 3622196 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.61 | 49.0 | 3.77e-01 | 95.9% | 37.5% |
| 4028685 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.61 | 53.0 | 4.13e-01 | 100.0% | 98.2% |
| 4588680 | 5068.1.1.0 ↗ | alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) | 0.61 | 43.0 | 3.08e-01 | 100.0% | 23.7% |
| 3860702 | 2004.5.1.13 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › SPA, Avl9 | 0.61 | 40.0 | 2.64e-01 | 85.7% | 16.1% |
| 4392601 | 304.36.1.1 ↗ | a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › DUF520 | 0.61 | 34.0 | 2.98e-01 | 81.6% | 37.0% |
| 3741546 | 109.4.1.1317 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C | 0.61 | 52.0 | 2.93e-01 | 100.0% | 7.2% |
| 4935350 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.60 | 52.0 | 3.66e-01 | 100.0% | 83.0% |
| 3937187 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.60 | 50.0 | 3.99e-01 | 100.0% | 44.5% |
| 1697870 | 3916.1.1.1 ↗ | alpha arrays › Helical domain in PB2 › Helical domain in PB2 › Helical domain in PB2 › Flu_PB2_4th | 0.60 | 41.0 | 3.68e-01 | 73.5% | 65.3% |
| 5042736 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.59 | 51.0 | 3.50e-01 | 100.0% | 37.8% |
| 4553364 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 48.0 | 4.36e-01 | 95.9% | 100.0% |
| 4968841 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 47.0 | 2.93e-01 | 95.9% | 19.7% |
| 3584973 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.59 | 48.0 | 3.97e-01 | 95.9% | 49.5% |
| 3228583 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.58 | 48.0 | 3.81e-01 | 100.0% | 81.7% |
| 3176040 | 109.4.1.32 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G | 0.58 | 47.0 | 2.92e-01 | 93.9% | 15.6% |
| 3838699 | 3783.1.1.0 ↗ | alpha bundles › Toxin RnlA C-terminal domain › Toxin RnlA C-terminal domain › Toxin RnlA C-terminal domain | 0.58 | 47.0 | 3.34e-01 | 100.0% | 54.6% |
| 3550136 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.57 | 49.0 | 3.80e-01 | 100.0% | 45.2% |
| 3482328 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.57 | 48.0 | 3.86e-01 | 100.0% | 53.3% |
| 3411883 | 604.1.1.63 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 | 0.57 | 47.0 | 3.68e-01 | 100.0% | 74.2% |
| 3301869 | 185.1.1.2 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › LTP_2 | 0.57 | 41.0 | 3.42e-01 | 79.6% | 57.9% |
| 4954786 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.57 | 47.0 | 4.07e-01 | 100.0% | 88.2% |
| 4073860 | 5086.1.1.67 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Neurensin | 0.56 | 48.0 | 3.59e-01 | 100.0% | 59.3% |
| 4015729 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.56 | 47.0 | 3.62e-01 | 100.0% | 47.2% |
| 3941265 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 46.0 | 3.30e-01 | 100.0% | 31.2% |
| 3262813 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.55 | 46.0 | 3.06e-01 | 100.0% | 23.1% |
| 5040463 | 2002.1.1.111 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI | 0.55 | 45.0 | 2.84e-01 | 100.0% | 16.6% |
| 5062332 | 2003.1.1.386 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C | 0.55 | 46.0 | 2.80e-01 | 100.0% | 95.1% |
| 3657469 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.55 | 44.0 | 3.58e-01 | 93.9% | 58.0% |
| 4224821 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.55 | 46.0 | 3.62e-01 | 100.0% | 44.3% |
| 4930133 | 2002.1.1.109 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › NeuB | 0.54 | 41.0 | 2.64e-01 | 85.7% | 93.0% |
| 3948124 | 3227.1.1.1 ↗ | alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC | 0.54 | 45.0 | 2.68e-01 | 100.0% | 11.5% |
| 60305 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.54 | 43.0 | 3.56e-01 | 100.0% | 47.2% |
| 4982343 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 46.0 | 3.29e-01 | 100.0% | 56.8% |
| 4029585 | 5081.1.1.2 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 | 0.54 | 46.0 | 3.07e-01 | 100.0% | 55.1% |
| 1240484 | 2002.1.1.111 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI | 0.53 | 44.0 | 2.77e-01 | 100.0% | 15.3% |
| 4096488 | 3291.1.1.52 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Neurensin | 0.53 | 44.0 | 3.40e-01 | 100.0% | 50.8% |
| None | — | 0.53 | 46.0 | 2.63e-01 | 100.0% | 9.4% | |
| 3256986 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.53 | 43.0 | 2.84e-01 | 95.9% | 40.8% |
| 4972068 | 2003.1.1.386 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C | 0.53 | 40.0 | 2.52e-01 | 98.0% | 68.3% |
| 3412176 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.53 | 46.0 | 3.34e-01 | 100.0% | 40.0% |
| 3593339 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.52 | 43.0 | 3.40e-01 | 100.0% | 42.6% |
| 4841992 | 604.2.1.1 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succ_DH_flav_C | 0.52 | 45.0 | 3.89e-01 | 100.0% | 66.7% |
| 3998932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 41.0 | 3.02e-01 | 100.0% | 38.2% |
| 3761667 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 42.0 | 3.72e-01 | 95.9% | 61.3% |
| 1298571 | 3207.1.1.1 ↗ | alpha bundles › PmoA › PmoA › PmoA › AMO | 0.52 | 40.0 | 2.62e-01 | 95.9% | 17.6% |
| 4942136 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.52 | 42.0 | 2.94e-01 | 95.9% | 75.7% |
| 3261517 | 5081.1.1.4 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DUF1751 | 0.51 | 38.0 | 2.99e-01 | 100.0% | 74.8% |
| None | — | 0.51 | 43.0 | 2.61e-01 | 100.0% | 98.2% |