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L2

Euk-Vir

Human_papillomavirus_132

L2__YP_004169289__Human_papillomavirus_132__909331

Identity

Accession:
YP_004169289 ↗
Protein ID:
L2
Kingdom:
euk

Quality

58.3 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Gammapapillomavirus› Human_papillomavirus_132

TaxID: 909331

Cluster

View cluster (133 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 249-261_324-364
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00513.24 best Late_protein_L2 54.4 1.60e-14 92.6% 7.6%
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2n8xA00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.61 43.0 3.13e-01 75.9% 28.3%
7s7rA01 2.60.40.2860 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 43.0 3.22e-01 75.9% 66.4%
4gzvA00 2.40.128.490 Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein PF14869 family, DUF4488 0.60 38.0 2.83e-01 75.9% 25.2%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.59 44.0 3.66e-01 83.3% 61.9%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.59 44.0 3.68e-01 83.3% 63.7%
2yxdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 43.0 3.11e-01 83.3% 27.9%
1v1qA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 40.0 3.25e-01 75.9% 39.1%
1l3iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 42.0 2.96e-01 85.2% 27.0%
3e05B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 42.0 2.97e-01 87.0% 27.1%
6pfzD02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 44.0 2.92e-01 92.6% 48.2%
3fhwA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 36.0 3.09e-01 72.2% 41.4%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 37.0 3.09e-01 75.9% 52.3%
3d9rB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 43.0 3.30e-01 90.7% 88.0%
3j7aV00 2.40.50.1000 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.53 37.0 2.80e-01 75.9% 39.0%
3aabB00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.00e-01 83.3% 38.7%
3ub1A01 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 35.0 2.78e-01 72.2% 77.9%
2lxxA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.51 41.0 3.19e-01 100.0% 68.4%
1wtuA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.51 39.0 3.42e-01 92.6% 56.6%
3en2A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 35.0 3.03e-01 72.2% 44.0%
5fokA02 2.40.170.20 Mainly Beta › Beta Barrel › Maltoporin; Chain A › TonB-dependent receptor, beta-barrel domain 0.51 43.0 2.55e-01 100.0% 30.9%
6rtqA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.51 44.0 3.33e-01 98.1% 70.7%
3ejvA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 40.0 2.96e-01 90.7% 95.0%
1e3uD00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.51 35.0 2.39e-01 75.9% 16.5%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.51 39.0 3.51e-01 92.6% 86.7%
1t5rB00 2.70.240.10 Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA 0.51 39.0 2.65e-01 94.4% 75.6%
2ndpA00 4.10.520.10 Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins 0.50 42.0 3.55e-01 100.0% 63.6%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3410286 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.72 52.0 4.24e-01 75.9% 48.4%
3284948 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.65 45.0 3.92e-01 74.1% 49.4%
4022601 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.62 44.0 3.50e-01 75.9% 91.8%
3534592 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.61 42.0 4.22e-01 75.9% 72.7%
5029815 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.61 48.0 3.33e-01 94.4% 60.5%
3785861 5.1.2.20 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › BMT 0.61 41.0 2.35e-01 70.4% 9.6%
3600488 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 45.0 3.44e-01 79.6% 68.8%
4951650 4121.1.1.1 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.60 47.0 3.02e-01 87.0% 21.1%
3897871 11.1.1.640 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.60 41.0 3.30e-01 74.1% 36.3%
3713176 5.1.4.223 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RIC1_2nd 0.59 48.0 2.98e-01 100.0% 38.4%
3483121 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 41.0 3.54e-01 75.9% 47.1%
None — 0.58 46.0 3.02e-01 92.6% 97.4%
4948943 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.58 47.0 4.14e-01 88.9% 74.4%
4640369 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.58 39.0 3.21e-01 75.9% 36.2%
3614657 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.57 44.0 2.58e-01 85.2% 15.6%
3591503 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 42.0 3.23e-01 88.9% 31.7%
3901462 11.1.1.1054 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26562 0.57 39.0 3.10e-01 72.2% 33.9%
5083453 304.139.1.3 ↗ a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › Cas_Cas7 0.56 40.0 2.60e-01 79.6% 52.3%
3667413 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 39.0 3.54e-01 77.8% 53.3%
3899290 11.1.1.1054 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26562 0.56 41.0 3.29e-01 81.5% 69.6%
3867644 3382.1.1.1 ↗ alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt 0.55 44.0 2.90e-01 100.0% 73.8%
4856794 304.112.1.0 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.55 39.0 3.60e-01 90.7% 55.8%
4029363 304.20.1.2 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › Nrap_D3 0.55 40.0 3.01e-01 81.5% 75.6%
4122961 2.1.1.122 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB_1 0.55 38.0 3.17e-01 74.1% 43.0%
5016531 11.1.1.347 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › T26-6p_Ig-like_dom_2 0.55 44.0 2.74e-01 96.3% 90.0%
3614143 292.2.1.1 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › POLO_box 0.55 45.0 3.56e-01 98.1% 53.2%
5036926 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 44.0 3.28e-01 90.7% 94.3%
3734626 171.1.1.1 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 0.54 39.0 2.61e-01 75.9% 75.0%
3249666 7541.1.1.1 ↗ a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.54 43.0 3.09e-01 100.0% 81.9%
3472421 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.54 45.0 3.49e-01 96.3% 77.7%
4396101 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.54 42.0 2.52e-01 88.9% 61.6%
294 2.1.1.6 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.54 39.0 2.98e-01 81.5% 60.0%
4012024 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.54 42.0 2.81e-01 94.4% 19.3%
4240255 230.1.1.5 ↗ a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.54 37.0 3.05e-01 75.9% 67.8%
3282895 912.1.1.0 ↗ few secondary structure elements › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain 0.54 45.0 3.08e-01 94.4% 83.1%
4997962 304.139.1.2 ↗ a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › RAMPs 0.54 45.0 2.96e-01 100.0% 93.5%
4068016 2.1.1.122 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB_1 0.53 37.0 3.04e-01 74.1% 41.0%
3716792 511.1.1.0 ↗ beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.53 43.0 3.27e-01 96.3% 47.7%
3707076 511.1.1.0 ↗ beta sandwiches › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain › Heat shock protein 70kD (HSP70), peptide-binding domain 0.53 47.0 3.36e-01 100.0% 71.5%
4120121 230.1.1.5 ↗ a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.53 36.0 3.08e-01 75.9% 71.8%
3225904 7084.1.1.1 ↗ few secondary structure elements › Highly disulfide-linked beta sandwich region of p43 › Highly disulfide-linked beta sandwich region of p43 › Highly disulfide-linked beta sandwich region of p43 › PF28734 0.53 43.0 3.58e-01 90.7% 66.3%
3592296 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 43.0 3.35e-01 92.6% 40.8%
4544858 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.53 42.0 2.58e-01 98.1% 49.1%
4629438 230.1.1.5 ↗ a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.52 36.0 3.04e-01 75.9% 70.9%
3470394 3382.1.1.1 ↗ alpha arrays › Protein Wnt-8 › Protein Wnt-8 › Protein Wnt-8 › wnt 0.52 40.0 2.50e-01 85.2% 28.7%
4351239 4967.1.1.6 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 0.52 36.0 2.84e-01 74.1% 69.2%
3593809 304.31.1.0 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase 0.52 40.0 3.30e-01 88.9% 77.3%
3892768 11.1.1.1054 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26562 0.52 38.0 3.14e-01 87.0% 80.8%
4223395 4967.1.1.25 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.52 41.0 2.55e-01 100.0% 13.7%
5057906 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.51 38.0 3.18e-01 83.3% 65.7%
3435653 4020.1.1.0 ↗ a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes 0.51 41.0 3.69e-01 98.1% 96.5%
4196358 230.1.1.5 ↗ a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › GCHY-1 0.51 40.0 3.26e-01 94.4% 94.2%
2505866 1.2.1.4 ↗ beta barrels › cradle loop barrel › Capsid protein protrusion (P) domain › Capsid protein protrusion (P) domain › Calici_coat, Calici_coat_C 0.51 39.0 2.91e-01 92.6% 31.8%
4955607 3435.1.1.0 ↗ a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC 0.50 37.0 2.62e-01 85.2% 84.7%
3228161 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.50 39.0 3.22e-01 92.6% 51.3%
3576101 304.112.1.0 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.50 41.0 3.11e-01 98.1% 50.0%
D2 medium residues 262-323
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00513.24 best Late_protein_L2 72.6 5.00e-20 100.0% 11.6%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4wuvA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 39.0 2.60e-01 87.1% 96.1%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3646895 327.7.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.51 41.0 3.55e-01 95.2% 78.2%