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LC680885.1__BDE75590.1__X__00052

Bact-Vir

LC680885.1__BDE75590.1__X__00052

Identity

Accession:
LC680885 ↗
Kingdom:
phage

Quality

87.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 93-159
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF20286.4 best divDNApol 35.9 3.80e-09 100.0% 9.0%
PF00136.27 DNA_pol_B 35.0 1.00e-08 97.0% 12.6%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k59A06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.91 62.0 7.31e-01 89.6% 100.0%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.91 69.0 7.30e-01 83.6% 89.8%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.89 60.0 6.34e-01 70.1% 77.0%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.89 81.0 6.04e-01 100.0% 43.1%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.87 60.0 4.81e-01 71.6% 39.5%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.86 68.0 7.06e-01 91.0% 88.9%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.86 70.0 4.19e-01 86.6% 14.4%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.86 69.0 6.71e-01 85.1% 84.9%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.85 71.0 5.28e-01 97.0% 38.3%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.85 69.0 7.10e-01 94.0% 90.6%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.85 66.0 5.80e-01 83.6% 58.8%
1vmgA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.84 60.0 5.60e-01 74.6% 62.2%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 69.0 6.83e-01 95.5% 85.5%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.82 69.0 4.29e-01 89.6% 52.4%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 68.0 6.52e-01 95.5% 77.9%
2c2jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.81 68.0 4.98e-01 100.0% 36.4%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.81 61.0 5.02e-01 79.1% 48.7%
5ux1D00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.81 64.0 4.50e-01 97.0% 28.9%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.80 57.0 5.52e-01 76.1% 67.6%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.80 73.0 5.26e-01 100.0% 41.0%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 73.0 6.06e-01 100.0% 68.2%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 72.0 6.71e-01 100.0% 100.0%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.77 66.0 6.19e-01 95.5% 76.5%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.77 59.0 6.07e-01 98.5% 84.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 63.0 6.02e-01 94.0% 77.2%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.76 59.0 5.14e-01 85.1% 61.8%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.76 60.0 5.85e-01 94.0% 79.2%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.75 61.0 5.98e-01 95.5% 80.6%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.75 61.0 4.24e-01 100.0% 27.2%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.75 68.0 5.62e-01 100.0% 58.6%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 67.0 5.71e-01 100.0% 75.0%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 65.0 5.41e-01 100.0% 65.3%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.73 66.0 5.38e-01 97.0% 94.8%
2qkdA02 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.72 58.0 4.53e-01 86.6% 75.0%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 66.0 5.57e-01 100.0% 81.3%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.72 56.0 4.83e-01 100.0% 53.7%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.71 64.0 5.37e-01 100.0% 83.0%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 54.0 4.71e-01 100.0% 53.2%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.70 55.0 4.26e-01 100.0% 37.5%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 57.0 5.48e-01 94.0% 79.5%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 55.0 5.14e-01 89.6% 83.5%
3ddeB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.68 54.0 3.81e-01 100.0% 26.0%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 52.0 5.27e-01 94.0% 87.5%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.68 56.0 4.69e-01 94.0% 52.1%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 57.0 5.07e-01 95.5% 66.7%
3jcuZ00 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.67 53.0 5.51e-01 95.5% 98.4%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.67 53.0 5.30e-01 89.6% 90.1%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 56.0 4.25e-01 98.5% 48.8%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 47.0 4.62e-01 94.0% 74.3%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.63 55.0 4.50e-01 98.5% 81.3%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 49.0 4.64e-01 95.5% 71.1%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 51.0 4.90e-01 100.0% 80.8%
1kf6C00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.59 50.0 4.02e-01 100.0% 48.5%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.56 49.0 3.83e-01 100.0% 45.4%
3nkuA00 1.10.357.170 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.54 46.0 3.51e-01 100.0% 54.0%
4didB01 1.20.58.450 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cell division control protein 42 homolog 0.54 44.0 3.72e-01 91.0% 83.3%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5011468 101.1.2.31 alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha 0.93 68.0 5.37e-01 77.6% 40.8%
3515796 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.93 65.0 4.67e-01 73.1% 28.8%
3287592 3443.1.1.0 alpha duplicates or obligate multimers › Get5 carboxyl domain › Get5 carboxyl domain › Get5 carboxyl domain 0.92 66.0 7.59e-01 74.6% 100.0%
3654599 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.90 76.0 6.65e-01 100.0% 63.2%
3993981 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 85.0 5.65e-01 100.0% 29.8%
1821875 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.90 71.0 7.59e-01 86.6% 94.9%
5007707 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.90 78.0 6.35e-01 100.0% 53.9%
3346233 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 61.0 5.90e-01 80.6% 64.0%
3273673 3291.1.1.54 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CC2D1A-B_DM14 0.88 72.0 5.45e-01 88.1% 40.0%
3237264 3755.4.1.82 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Snf7 0.88 73.0 5.74e-01 95.5% 45.4%
4968618 611.6.1.0 alpha bundles › N-cbl like › PT26-6P helical domain › PT26-6P helical domain 0.87 72.0 6.18e-01 86.6% 60.2%
5012084 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.87 81.0 5.40e-01 100.0% 30.2%
4029167 3712.1.1.0 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 0.86 70.0 5.72e-01 94.0% 50.4%
3372432 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.86 69.0 6.52e-01 94.0% 72.5%
3357192 101.1.9.123 alpha arrays › HTH › HTH › Putative DNA-binding domain › RWP-RK 0.85 67.0 5.30e-01 89.6% 44.0%
3595968 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.84 71.0 6.66e-01 95.5% 75.0%
4406905 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.83 69.0 6.81e-01 95.5% 84.3%
4595635 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.83 70.0 5.11e-01 94.0% 36.9%
3600080 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 70.0 4.36e-01 89.6% 52.2%
3390353 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.83 66.0 6.75e-01 95.5% 87.7%
4619538 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.82 67.0 5.50e-01 95.5% 50.4%
3582234 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 61.0 5.34e-01 94.0% 53.0%
4206858 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.82 66.0 5.48e-01 95.5% 50.4%
4436335 3390.1.1.0 extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT 0.81 53.0 6.06e-01 71.6% 100.0%
3577682 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.80 64.0 5.05e-01 100.0% 42.1%
4254477 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.80 65.0 5.60e-01 95.5% 58.0%
3601441 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 65.0 5.63e-01 97.0% 59.0%
3704762 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.79 65.0 5.29e-01 97.0% 48.8%
3794775 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.79 65.0 6.62e-01 94.0% 92.3%
3353220 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.77 62.0 5.35e-01 94.0% 56.2%
3698336 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 71.0 6.50e-01 100.0% 82.4%
3732397 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 68.0 5.46e-01 94.0% 81.7%
5008343 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.77 62.0 5.26e-01 100.0% 54.3%
4129436 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.76 62.0 5.27e-01 95.5% 55.2%
5052878 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 67.0 5.93e-01 100.0% 77.9%
3591222 604.1.1.198 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › BAG 0.74 63.0 5.65e-01 100.0% 67.4%
3526861 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.73 66.0 5.48e-01 100.0% 59.1%
3681259 5058.1.1.57 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › V-SNARE 0.73 62.0 5.77e-01 98.5% 74.1%
3645891 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.73 65.0 4.36e-01 100.0% 43.5%
3517721 7111.1.1.0 alpha bundles › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain 0.72 62.0 4.51e-01 97.0% 48.1%
3634960 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.71 61.0 5.17e-01 95.5% 60.0%
3503210 616.1.1.0 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.69 61.0 5.95e-01 100.0% 93.3%
3697969 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.67 56.0 3.40e-01 95.5% 17.7%
3664670 604.1.1.189 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Occludin_ELL 0.66 59.0 4.60e-01 100.0% 60.0%
4447644 2004.1.1.514 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_29, SbcC_Walker_B 0.66 59.0 3.64e-01 100.0% 26.1%
D2 medium residues 7-84
PDB
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ag6A02 1.10.8.730 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.68 42.0 3.72e-01 71.8% 43.6%
1wgfA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.65 43.0 4.94e-01 78.2% 100.0%
1sd4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 35.0 3.84e-01 75.6% 65.6%
4rayA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 35.0 3.41e-01 76.9% 51.8%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 35.0 3.47e-01 84.6% 52.9%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.58 36.0 3.53e-01 89.7% 55.7%
3m8eA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 30.0 2.81e-01 71.8% 37.6%
2z6vA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 2.95e-01 92.3% 59.7%
1fcqA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 46.0 3.12e-01 93.6% 68.2%
3elkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 37.0 3.43e-01 70.5% 99.0%
1nrwA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.55 43.0 3.64e-01 93.6% 50.8%
2xigA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 33.0 3.18e-01 76.9% 49.5%
6opmD01 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.55 44.0 3.22e-01 92.3% 39.5%
1u5tB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 31.0 3.28e-01 80.8% 65.2%
3mwmA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 31.0 3.18e-01 76.9% 58.7%
2q1fA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.52 42.0 2.78e-01 94.9% 83.9%
4n06A02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.51 43.0 3.05e-01 96.2% 36.4%
4inaA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 39.0 3.00e-01 85.9% 60.9%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4942265 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.66 39.0 3.84e-01 75.6% 54.1%
3216952 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.63 37.0 3.68e-01 70.5% 54.1%
5056667 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.61 49.0 3.08e-01 88.5% 48.7%
3390907 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.61 35.0 3.43e-01 71.8% 52.4%
4946048 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 37.0 3.69e-01 76.9% 60.0%
4995581 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.59 35.0 3.20e-01 79.5% 45.0%
5000704 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 34.0 3.28e-01 75.6% 50.0%
3493459 101.1.2.90 alpha arrays › HTH › HTH › winged helix domain › HTH_9 0.57 31.0 3.03e-01 78.2% 45.9%
3240388 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 49.0 3.35e-01 100.0% 73.2%
4955611 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.55 32.0 3.01e-01 75.6% 42.3%
3394692 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 37.0 3.38e-01 76.9% 52.4%
4971992 2003.1.1.386 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C 0.55 46.0 3.03e-01 98.7% 71.9%
4964386 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 32.0 3.04e-01 75.6% 46.3%
3590229 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.54 36.0 3.22e-01 79.5% 47.0%
5049455 101.1.2.54 alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.53 36.0 3.04e-01 71.8% 82.1%
5035624 101.1.2.54 alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.52 31.0 3.04e-01 75.6% 51.8%
4954915 2003.1.1.386 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C 0.52 43.0 2.79e-01 94.9% 27.4%
3958566 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.51 30.0 2.91e-01 73.1% 47.8%
4585740 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.50 35.0 3.43e-01 75.6% 71.1%
D3 medium residues 166-262
PDB
D4 medium residues 263-325_342-405
PDB
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6o0aA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 48.0 4.59e-01 92.1% 80.5%
4o8sA02 1.20.58.1790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain 0.54 40.0 4.31e-01 95.3% 91.6%
2nrlA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 45.0 4.32e-01 89.0% 84.1%
5c9eB01 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 35.0 4.10e-01 84.3% 100.0%
1or4B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 41.0 3.88e-01 85.0% 71.5%
1bvyB00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.51 40.0 2.83e-01 85.8% 50.7%
1ic8A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.50 25.0 2.85e-01 89.0% 60.6%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3284022 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.59 49.0 4.56e-01 92.1% 70.6%
5058827 4033.1.1.1 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.56 42.0 4.36e-01 100.0% 83.3%
4939254 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.55 42.0 3.57e-01 81.1% 81.2%
3420900 5050.1.1.33 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_5 0.51 40.0 3.31e-01 82.7% 56.9%
3257841 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.51 34.0 3.82e-01 81.9% 87.0%
3368919 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.50 40.0 2.91e-01 86.6% 50.4%
D5 medium residues 326-341_406-464
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20286.4 best divDNApol 44.0 1.30e-11 96.0% 8.5%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qexA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.87 64.0 4.36e-01 77.3% 47.7%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.74 55.0 4.66e-01 77.3% 92.3%
2i79D00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 47.0 3.71e-01 98.7% 80.2%
2rrfA00 2.30.29.160 Mainly Beta › Roll › PH-domain like › Zinc finger FYVE domain-containing protein 21, C-terminal 0.54 39.0 3.26e-01 78.7% 66.7%
2shpB03 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.53 42.0 2.92e-01 89.3% 33.1%
1oh1A00 2.40.310.10 Mainly Beta › Beta Barrel › Staphostatins › beta-Barrel protease inhibitors 0.52 38.0 3.42e-01 78.7% 84.4%
3k50A02 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.52 35.0 3.27e-01 70.7% 90.0%
3kspA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 46.0 3.87e-01 100.0% 90.7%
3fb9B00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.51 34.0 3.36e-01 74.7% 63.1%
3tqhA01 3.90.180.10 Alpha Beta › Alpha-Beta Complex › Quinone Oxidoreductase; Chain A, domain 1 › Medium-chain alcohol dehydrogenases, catalytic domain 0.50 42.0 3.27e-01 97.3% 79.3%
3grdA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 38.0 3.23e-01 82.7% 90.2%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4939489 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.89 71.0 4.99e-01 82.7% 50.8%
3506687 304.48.1.17 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.77 71.0 4.35e-01 100.0% 21.6%
4009369 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.65 45.0 3.92e-01 72.0% 67.0%
3584298 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.57 39.0 2.86e-01 76.0% 27.9%
5055963 809.2.1.0 a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.55 38.0 3.97e-01 78.7% 77.1%
3444611 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 37.0 2.71e-01 74.7% 72.8%
3677760 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.52 37.0 2.58e-01 76.0% 79.6%
3274309 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.51 44.0 2.68e-01 100.0% 48.8%
3695678 3924.1.1.0 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 0.51 37.0 2.36e-01 80.0% 23.0%
3636954 7579.1.1.92 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1, Abhydrolase_6 0.51 36.0 2.35e-01 76.0% 15.8%
3937102 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.50 41.0 3.22e-01 93.3% 43.9%
3211848 5.1.4.453 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Kelch_KLHDC2_KLHL20_DRC7 0.50 42.0 2.74e-01 98.7% 41.3%
D6 medium residues 494-642
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20286.4 best divDNApol 38.3 7.10e-10 100.0% 22.2%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2w82A03 1.10.10.1190 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Antirestriction protein ArdA, domain 3 0.67 20.0 3.16e-01 86.6% 62.9%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.56 50.0 4.85e-01 96.0% 89.8%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3484038 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.64 52.0 4.59e-01 99.3% 61.0%
3314223 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.58 53.0 5.22e-01 98.7% 91.3%
3514097 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.58 53.0 5.12e-01 98.7% 87.1%
3480544 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.58 53.0 5.18e-01 98.7% 90.3%
4978606 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.58 54.0 5.32e-01 99.3% 95.5%
4025114 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.58 52.0 5.02e-01 98.0% 93.5%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.57 52.0 4.75e-01 98.7% 75.8%
3214821 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.57 49.0 4.95e-01 97.3% 92.7%