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LC680885.1__BDE75707.1__X__00169

Bact-Vir

LC680885.1__BDE75707.1__X__00169

Identity

Accession:
LC680885 ↗
Kingdom:
phage

Quality

84.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 228-389
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14528.12 best LAGLIDADG_3 26.3 9.50e-06 45.7% 64.6%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7qssA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.81 58.0 5.51e-01 72.8% 89.9%
8dy9I01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.75 62.0 5.61e-01 85.2% 93.7%
5a72A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.73 51.0 5.18e-01 93.8% 73.2%
1af5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.71 47.0 5.38e-01 96.3% 87.3%
4z1xA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.70 49.0 5.24e-01 71.0% 84.6%
2ex5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.70 50.0 4.55e-01 72.2% 81.2%
6vudA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.70 30.0 4.43e-01 83.3% 89.3%
3hyiA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.69 59.0 5.60e-01 90.1% 92.1%
3ko2A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.68 48.0 4.86e-01 95.7% 72.7%
2cw8A03 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.67 57.0 5.62e-01 87.0% 100.0%
3hz7A00 3.30.110.40 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › TusA-like domain 0.66 30.0 4.43e-01 76.5% 95.9%
1ef0B02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.65 57.0 5.37e-01 91.4% 96.3%
2lrrA00 3.30.1370.50 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain 0.62 29.0 4.17e-01 76.5% 100.0%
1ub9A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 31.0 3.81e-01 83.3% 88.0%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.55 27.0 3.67e-01 70.4% 97.3%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 31.0 3.67e-01 78.4% 83.8%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.54 27.0 3.52e-01 80.2% 87.4%
2d9oA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 27.0 3.35e-01 75.9% 77.0%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.53 33.0 3.24e-01 88.9% 55.4%
2bv6A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 31.0 3.32e-01 79.6% 68.4%
3cu7A11 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.51 43.0 3.45e-01 90.7% 55.1%
4ks9A01 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.51 37.0 4.18e-01 90.1% 96.8%
2d9iA00 3.30.1370.110 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.50 28.0 3.50e-01 70.4% 89.6%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3604140 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.89 61.0 5.79e-01 71.0% 61.1%
5012959 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.84 57.0 6.89e-01 73.5% 100.0%
4997781 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.83 53.0 6.60e-01 78.4% 100.0%
4474382 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.82 58.0 6.58e-01 71.6% 100.0%
4669669 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.81 54.0 6.57e-01 96.9% 99.1%
4934140 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.79 53.0 6.24e-01 80.9% 94.8%
4629526 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.79 57.0 4.46e-01 74.1% 52.9%
4938255 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.78 38.0 5.33e-01 85.2% 95.0%
4288172 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.77 53.0 5.85e-01 70.4% 86.2%
5012700 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.77 40.0 5.42e-01 90.1% 96.5%
4979525 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.77 65.0 6.07e-01 88.3% 99.5%
5027689 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 37.0 5.19e-01 86.4% 96.2%
4977674 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 65.0 5.80e-01 90.1% 96.4%
4096150 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.75 54.0 6.07e-01 82.1% 94.4%
4993734 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 69.0 6.10e-01 95.7% 100.0%
4937614 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 39.0 4.18e-01 86.4% 57.2%
5028300 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.74 38.0 5.10e-01 85.8% 94.1%
3177415 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.73 47.0 5.63e-01 92.6% 95.5%
1687926 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.73 51.0 5.18e-01 93.8% 73.2%
3282307 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.72 41.0 5.30e-01 84.0% 96.8%
4377946 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.70 50.0 5.59e-01 95.1% 90.0%
4276586 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.67 48.0 5.48e-01 95.1% 97.5%
4979624 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.66 39.0 4.66e-01 88.3% 86.4%
4084747 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.62 57.0 4.43e-01 96.9% 86.3%
3543869 320.1.1.1 a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H 0.56 30.0 3.79e-01 80.2% 87.4%
3926462 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.54 32.0 3.90e-01 82.1% 89.5%
5009161 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.51 48.0 3.81e-01 98.8% 67.3%
4405940 242.1.1.8 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3, Intein_splicing 0.51 48.0 3.34e-01 98.8% 44.3%
D2 high residues 721-845
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 48.6 8.20e-13 97.6% 27.2%
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4z4qA04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.93 65.0 7.68e-01 72.8% 100.0%
3lpxA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.91 65.0 7.22e-01 73.6% 100.0%
1zvuA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.90 83.0 7.97e-01 100.0% 86.4%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.87 40.0 4.02e-01 91.2% 44.9%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 48.0 4.03e-01 91.2% 37.0%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.82 48.0 3.90e-01 92.0% 34.3%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 45.0 4.60e-01 91.2% 56.6%
8gccA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.80 62.0 6.75e-01 80.0% 100.0%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 47.0 5.16e-01 85.6% 71.4%
1bgwA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.79 57.0 6.11e-01 75.2% 100.0%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.78 44.0 5.49e-01 89.6% 87.5%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.78 46.0 4.43e-01 95.2% 51.7%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 47.0 4.54e-01 96.0% 54.2%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.75 45.0 4.77e-01 92.0% 67.3%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.74 44.0 4.58e-01 89.6% 62.9%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 44.0 4.71e-01 90.4% 67.3%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.73 38.0 4.52e-01 89.6% 72.9%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 49.0 4.02e-01 91.2% 40.0%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 41.0 4.35e-01 89.6% 61.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 44.0 4.70e-01 91.2% 67.9%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 38.0 4.16e-01 90.4% 61.8%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 43.0 4.31e-01 93.6% 58.7%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.71 41.0 4.40e-01 91.2% 65.4%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 38.0 4.16e-01 91.2% 62.7%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 40.0 3.88e-01 91.2% 50.0%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 41.0 4.39e-01 92.8% 68.2%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 41.0 4.45e-01 95.2% 70.2%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 43.0 4.56e-01 93.6% 71.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 45.0 4.92e-01 91.2% 83.0%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.67 58.0 4.96e-01 91.2% 93.8%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 45.0 3.96e-01 94.4% 48.6%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 39.0 3.99e-01 89.6% 60.8%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.64 43.0 4.27e-01 97.6% 64.7%
7um4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 43.0 3.37e-01 91.2% 33.9%
7dluA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 34.0 3.74e-01 85.6% 64.8%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 39.0 4.13e-01 96.8% 72.5%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 45.0 3.41e-01 95.2% 33.7%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 31.0 3.69e-01 82.4% 73.5%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 44.0 3.95e-01 91.2% 55.5%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.60 45.0 4.25e-01 91.2% 66.4%
1jqkA03 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 53.0 4.70e-01 97.6% 79.4%
3i01A01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 51.0 4.55e-01 96.0% 81.9%
4h3tA02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.57 40.0 3.87e-01 99.2% 63.1%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 50.0 3.89e-01 96.0% 74.6%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.56 48.0 4.63e-01 91.2% 87.2%
4dveA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.56 34.0 2.94e-01 95.2% 39.7%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.56 46.0 4.53e-01 89.6% 97.1%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 47.0 3.56e-01 91.2% 39.9%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 49.0 3.84e-01 96.8% 77.1%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.54 47.0 3.41e-01 91.2% 37.5%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.54 48.0 3.83e-01 96.8% 73.9%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.53 35.0 3.75e-01 89.6% 77.1%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 47.0 3.78e-01 96.8% 71.0%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.52 46.0 4.08e-01 96.0% 97.7%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 47.0 3.81e-01 98.4% 70.3%
2awiA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.52 20.0 2.67e-01 90.4% 64.2%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 43.0 3.92e-01 93.6% 68.9%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 46.0 4.39e-01 100.0% 97.3%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.51 44.0 3.80e-01 93.6% 72.0%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.50 36.0 3.47e-01 74.4% 93.8%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4883080 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.94 88.0 8.54e-01 98.4% 90.3%
1297277 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 89.0 7.64e-01 100.0% 68.5%
5083298 4016.1.1.0 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.93 88.0 8.21e-01 100.0% 82.7%
4946213 4016.1.1.18 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_gyraseA_C 0.93 88.0 8.30e-01 100.0% 85.5%
4373100 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 88.0 8.27e-01 100.0% 85.5%
4552385 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 86.0 7.86e-01 100.0% 78.1%
1302406 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 87.0 8.16e-01 100.0% 83.7%
5024978 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 87.0 8.23e-01 100.0% 85.5%
3345589 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 87.0 7.39e-01 100.0% 66.8%
4043618 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 85.0 7.95e-01 100.0% 82.0%
4174306 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.91 84.0 7.83e-01 100.0% 80.7%
4024264 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 85.0 8.24e-01 100.0% 91.1%
4299749 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 86.0 8.08e-01 100.0% 88.3%
4932829 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 85.0 7.99e-01 100.0% 85.5%
1780091 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.89 84.0 7.67e-01 100.0% 81.0%
4218225 4016.1.1.1 alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 83.0 7.67e-01 100.0% 81.9%
3959880 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.87 61.0 7.09e-01 72.8% 98.9%
3917600 604.1.1.6 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 0.87 47.0 4.84e-01 91.2% 56.7%
3782809 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.82 44.0 3.81e-01 91.2% 36.7%
4963648 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.81 49.0 3.15e-01 91.2% 15.3%
3960319 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.81 47.0 4.22e-01 91.2% 42.9%
4296017 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.80 46.0 4.59e-01 91.2% 55.4%
4935333 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.79 51.0 4.75e-01 91.2% 54.7%
4022306 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.77 49.0 4.58e-01 91.2% 53.3%
3920960 604.8.1.2 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Mitofilin 0.76 48.0 4.73e-01 91.2% 60.8%
3613594 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 42.0 4.13e-01 91.2% 52.6%
4418753 3755.3.1.363 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T1-F 0.71 45.0 3.42e-01 94.4% 28.1%
4020772 4207.1.1.64 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › PF30554 0.70 43.0 3.59e-01 90.4% 36.6%
4465966 632.11.1.10 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA 0.70 47.0 4.67e-01 96.0% 65.4%
3445405 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 39.0 4.04e-01 92.8% 56.7%
3557114 604.1.1.66 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.69 42.0 4.45e-01 90.4% 68.2%
4390743 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.69 38.0 3.45e-01 94.4% 40.6%
3635376 3755.3.1.298 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING 0.68 48.0 4.71e-01 91.2% 66.7%
4420057 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 45.0 4.41e-01 91.2% 63.7%
3393646 102.1.3.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain 0.67 37.0 3.78e-01 88.0% 55.8%
3714313 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 41.0 4.45e-01 83.2% 75.2%
4940100 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.64 42.0 3.92e-01 91.2% 53.5%
4012748 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.64 48.0 3.52e-01 91.2% 31.3%
3408532 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 50.0 4.40e-01 91.2% 58.8%
5039743 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.63 45.0 4.09e-01 91.2% 55.2%
3197870 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 44.0 4.31e-01 94.4% 66.7%
4305317 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.62 51.0 3.13e-01 86.4% 49.1%
4515899 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 42.0 3.75e-01 93.6% 50.0%
4972577 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.61 50.0 3.81e-01 91.2% 40.4%
4974229 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.60 44.0 3.87e-01 91.2% 53.1%
3698277 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 52.0 4.76e-01 97.6% 71.2%
3945729 604.32.1.0 alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY 0.60 46.0 4.54e-01 91.2% 76.2%
4535441 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.60 50.0 4.39e-01 91.2% 61.7%
4976068 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 48.0 3.20e-01 88.0% 22.0%
3742628 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 41.0 3.87e-01 95.2% 58.4%
3315414 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.59 48.0 4.20e-01 93.6% 59.4%
3330879 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 43.0 4.35e-01 96.8% 76.0%
4145667 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.58 48.0 4.13e-01 91.2% 56.4%
4153184 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.58 47.0 4.20e-01 91.2% 60.6%
5016953 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.58 51.0 4.62e-01 91.2% 71.2%
4937093 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 48.0 4.90e-01 91.2% 90.0%
4993051 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.58 51.0 3.19e-01 91.2% 41.5%
3728232 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.57 49.0 4.22e-01 91.2% 93.2%
3235287 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 48.0 3.72e-01 91.2% 90.4%
3498458 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 49.0 4.45e-01 91.2% 86.1%
3515796 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 48.0 4.32e-01 91.2% 67.1%
4116038 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.56 49.0 4.53e-01 91.2% 76.1%
4997710 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.56 43.0 4.47e-01 81.6% 100.0%
3610147 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.56 49.0 4.41e-01 91.2% 70.1%
3692488 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 41.0 3.40e-01 100.0% 42.7%
3264853 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.56 39.0 3.83e-01 94.4% 65.9%
5064482 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 46.0 4.16e-01 87.2% 69.1%
5070059 3834.1.1.25 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.55 47.0 3.69e-01 91.2% 54.0%
3494742 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.54 47.0 4.38e-01 94.4% 100.0%
3869820 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.54 47.0 2.99e-01 92.0% 45.6%
5076969 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 45.0 3.85e-01 91.2% 96.4%
3692270 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.53 46.0 3.72e-01 94.4% 54.5%
3410475 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.53 48.0 4.16e-01 98.4% 79.5%
4139499 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.51 44.0 2.84e-01 91.2% 21.6%
3715891 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 42.0 3.85e-01 91.2% 66.7%
4030374 2004.1.1.36 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N 0.51 41.0 2.77e-01 91.2% 24.1%
3623247 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 45.0 3.70e-01 96.0% 84.5%
4676422 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.50 43.0 3.84e-01 92.0% 82.3%
D3 medium residues 15-117_490-532
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 148.0 5.70e-43 91.1% 30.4%
D4 medium residues 162-226_454-483
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14890.12 best Intein_splicing 35.8 9.60e-09 68.4% 35.5%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1am2A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.95 91.0 7.08e-01 100.0% 70.7%
6vgwA01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.90 76.0 6.53e-01 100.0% 59.6%
1mi8A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.90 79.0 6.76e-01 100.0% 61.7%
1dq3A01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.88 83.0 6.56e-01 100.0% 57.1%
4o1sA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.87 82.0 6.59e-01 100.0% 55.9%
4e2tB00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.87 82.0 6.59e-01 100.0% 58.0%
2cw8A01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.85 80.0 6.45e-01 100.0% 56.2%
5o9iA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.84 79.0 6.35e-01 100.0% 57.9%
2lcjA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.83 78.0 6.11e-01 100.0% 62.2%
2jmzA01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.83 76.0 6.15e-01 100.0% 55.4%
1at0A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.83 77.0 6.59e-01 100.0% 66.9%
1zdeA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.81 77.0 6.27e-01 100.0% 61.9%
2imzA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.81 76.0 6.47e-01 100.0% 66.2%
3bcwA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.65 29.0 2.83e-01 71.6% 36.5%
6m3aA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 31.0 3.67e-01 72.6% 74.2%
3mb5A01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.56 34.0 4.08e-01 70.5% 93.5%
4kncA02 2.60.120.1380 Mainly Beta › Sandwich › Jelly Rolls › C-terminal carbohydrate-binding module 0.54 32.0 2.96e-01 72.6% 47.0%
2jqjA01 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.52 38.0 3.47e-01 77.9% 88.5%
3cpxA02 2.40.30.40 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Peptidase M42, domain 2 0.52 29.0 3.43e-01 81.1% 82.3%
4jonC00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.51 38.0 3.61e-01 81.1% 96.6%
3mfiA04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.51 34.0 3.14e-01 72.6% 54.6%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3949431 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.95 92.0 7.63e-01 100.0% 65.3%
4291841 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.95 80.0 6.44e-01 100.0% 50.3%
4994372 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.95 80.0 7.30e-01 100.0% 69.2%
4084747 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.95 92.0 6.04e-01 100.0% 83.7%
4544734 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.95 92.0 6.76e-01 100.0% 75.2%
5013038 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.95 83.0 6.70e-01 100.0% 53.8%
4993732 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.94 76.0 6.80e-01 100.0% 64.0%
5023539 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.93 82.0 6.79e-01 100.0% 56.8%
5078549 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.93 85.0 6.92e-01 100.0% 56.9%
4940451 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.92 83.0 7.23e-01 100.0% 66.7%
4457379 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.91 78.0 6.63e-01 100.0% 58.6%
4946209 69.1.1.18 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › DNA_topoisoIV 0.91 88.0 6.53e-01 100.0% 80.5%
4998392 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.91 88.0 7.01e-01 100.0% 69.7%
3282306 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.90 77.0 6.73e-01 100.0% 63.0%
5035476 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.90 86.0 7.00e-01 100.0% 69.4%
3952464 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.90 78.0 6.58e-01 100.0% 59.3%
4993813 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.90 83.0 6.76e-01 100.0% 57.5%
4170121 69.1.1.11 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › PT-HINT, Intein_splicing 0.89 83.0 6.66e-01 100.0% 54.7%
3949584 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.89 85.0 7.10e-01 100.0% 70.0%
4979524 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.89 85.0 6.01e-01 100.0% 70.4%
5030213 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.89 83.0 6.93e-01 100.0% 62.0%
3603291 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 81.0 6.44e-01 100.0% 52.6%
2553113 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.88 76.0 6.72e-01 100.0% 66.4%
2445477 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 79.0 6.54e-01 100.0% 57.8%
4993437 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 84.0 7.09e-01 100.0% 72.9%
5012957 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 84.0 6.63e-01 100.0% 58.3%
3963364 69.1.1.3 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › PT-HINT 0.88 79.0 6.67e-01 100.0% 61.4%
5022295 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.88 82.0 6.62e-01 100.0% 56.4%
4039971 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 84.0 6.61e-01 100.0% 57.7%
3604383 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.88 83.0 6.17e-01 100.0% 71.2%
4993808 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.87 83.0 6.96e-01 100.0% 64.8%
4983458 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.87 83.0 6.68e-01 100.0% 57.6%
4977673 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.87 83.0 6.04e-01 100.0% 74.2%
4335483 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.87 82.0 6.02e-01 100.0% 69.8%
4629526 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.87 82.0 5.52e-01 100.0% 80.6%
4993853 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.87 82.0 6.64e-01 100.0% 57.6%
4982797 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.86 81.0 6.81e-01 100.0% 64.1%
4930925 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.86 78.0 6.68e-01 100.0% 64.3%
4984220 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.86 78.0 6.46e-01 100.0% 58.7%
4993128 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.86 82.0 6.68e-01 100.0% 65.6%
4930433 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.85 81.0 6.68e-01 100.0% 62.6%
5002632 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.85 79.0 6.58e-01 100.0% 61.7%
5066163 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.85 81.0 6.95e-01 100.0% 70.7%
5029355 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.85 80.0 6.74e-01 100.0% 64.7%
5031914 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.85 80.0 6.23e-01 100.0% 56.2%
5014854 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.85 80.0 5.93e-01 100.0% 65.6%
4997604 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.84 75.0 6.06e-01 100.0% 52.9%
4998394 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.84 81.0 6.62e-01 100.0% 71.0%
4070999 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.84 79.0 6.56e-01 100.0% 62.6%
4993454 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.84 79.0 5.74e-01 100.0% 70.2%
4943244 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.84 78.0 6.28e-01 100.0% 55.3%
4600944 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.84 79.0 6.27e-01 100.0% 55.4%
4487998 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.84 79.0 6.26e-01 100.0% 55.4%
3511246 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.83 79.0 6.39e-01 100.0% 61.8%
5052154 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.83 78.0 6.36e-01 100.0% 58.8%
5065032 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.83 79.0 6.40e-01 100.0% 61.8%
2546507 69.1.1.2 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hom_end_hint 0.83 78.0 6.66e-01 100.0% 70.6%
4999902 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.83 78.0 6.62e-01 100.0% 69.7%
4971412 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.83 79.0 6.18e-01 100.0% 60.6%
4945569 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.83 79.0 6.51e-01 100.0% 64.5%
4993871 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.83 64.0 5.95e-01 80.0% 67.8%
3603738 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.82 78.0 6.68e-01 100.0% 68.6%
3518586 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.82 76.0 5.79e-01 100.0% 48.3%
3934143 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.82 77.0 6.62e-01 100.0% 68.6%
2323756 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.81 77.0 6.33e-01 100.0% 69.0%
4933756 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.81 77.0 6.60e-01 100.0% 69.3%
4940699 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.81 77.0 6.36e-01 100.0% 61.3%
3936057 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.81 76.0 6.32e-01 100.0% 68.8%
4127166 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.81 76.0 6.38e-01 100.0% 68.7%
4500960 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.81 75.0 6.42e-01 100.0% 66.2%
3230518 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.80 75.0 6.26e-01 100.0% 67.7%
3517362 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.80 75.0 6.40e-01 100.0% 66.7%
3877825 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.80 75.0 5.64e-01 100.0% 49.0%
3215378 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.80 75.0 6.31e-01 100.0% 70.0%
3234017 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.80 74.0 5.97e-01 100.0% 63.4%
3861422 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.79 74.0 5.74e-01 100.0% 52.1%
5035795 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.78 71.0 6.11e-01 100.0% 64.1%
4932851 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.78 68.0 6.02e-01 100.0% 65.9%
4934481 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.76 70.0 5.96e-01 100.0% 73.6%
4950409 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 68.0 5.77e-01 100.0% 63.9%
4012287 69.1.1.5 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Vint 0.74 53.0 4.21e-01 74.7% 65.4%
4348482 4004.1.1.3 beta sandwiches › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like › NAD kinase beta sandwich domain-like › NAD_kinase_C 0.60 44.0 3.65e-01 76.8% 84.6%
4123180 4.1.1.96 beta barrels › SH3 › SH3 › SH3 › Hfq 0.59 31.0 3.49e-01 70.5% 65.3%
3571451 10.4.1.0 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain 0.54 28.0 2.61e-01 75.8% 35.8%
D5 medium residues 391-453
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 45.0 3.92e-01 96.8% 78.3%
7v8uA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 45.0 3.10e-01 98.4% 47.2%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4982983 101.1.10.3 alpha arrays › HTH › HTH › Cyclin-like › TFIIB 0.56 45.0 4.04e-01 93.7% 82.1%
D6 medium residues 533-560_579-711
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 75.2 7.00e-21 100.0% 39.2%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xppD00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.66 34.0 4.14e-01 74.5% 77.2%
1z1dB00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.58 34.0 3.73e-01 76.4% 69.5%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
396210 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 90.0 7.67e-01 100.0% 77.5%
3962339 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.93 89.0 8.44e-01 99.4% 100.0%
3590557 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 89.0 8.25e-01 100.0% 92.8%
4624017 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 89.0 8.49e-01 99.4% 98.3%
4024263 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 89.0 7.87e-01 100.0% 98.1%
4946212 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 88.0 8.31e-01 99.4% 100.0%
4855517 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.90 88.0 7.62e-01 100.0% 77.9%
3965475 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 87.0 7.86e-01 100.0% 99.0%
4266765 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.89 86.0 8.54e-01 100.0% 98.2%
2140592 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 83.0 7.94e-01 100.0% 98.9%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.79 75.0 7.33e-01 100.0% 98.2%
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 74.0 6.91e-01 100.0% 87.2%
3277529 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 74.0 7.42e-01 98.8% 100.0%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 74.0 7.20e-01 100.0% 97.7%
3188905 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.77 72.0 6.96e-01 99.4% 97.8%
3096551 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.75 70.0 6.63e-01 99.4% 98.9%
4935115 305.1.1.2 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 0.67 36.0 4.40e-01 74.5% 81.0%
5011372 306.6.1.0 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like 0.66 36.0 4.54e-01 78.9% 89.5%
4143020 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.54 39.0 3.26e-01 73.3% 96.3%
4529236 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.54 40.0 3.36e-01 76.4% 95.2%
4059572 242.1.1.5 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › WhiA_N 0.50 31.0 3.63e-01 82.6% 88.2%
D7 medium residues 869-1028
PDB
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF03989.19 best DNA_gyraseA_C 12.6 1.10e-01 30.6% 50.0%
PF03989.19 DNA_gyraseA_C 13.9 4.20e-02 25.0% 75.0%
PF03989.19 DNA_gyraseA_C 20.4 3.70e-04 20.6% 60.4%
D8 medium residues 1029-1184
PDB
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF03989.19 best DNA_gyraseA_C 23.6 3.80e-05 31.4% 93.8%
PF03989.19 DNA_gyraseA_C 28.6 1.10e-06 30.8% 87.5%
PF03989.19 DNA_gyraseA_C 16.7 5.40e-03 30.1% 93.8%