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LC754405.1__BDX35546.1__MN1_790__00079
Bact-VirLC754405.1__BDX35546.1__MN1_790__00079
Identity
- Accession:
- LC754405 ↗
- Kingdom:
- phage
Quality
76.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-173
Domain cluster:
rep: OL597546.1__UUB23297.1__X__00001__D24-147
D2
high
residues 186-270
D3
medium
residues 277-329
Domain cluster:
representative
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6a7hA01 | 1.20.140.180 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.91 | 69.0 | 5.02e-01 | 84.9% | 32.6% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.90 | 83.0 | 7.36e-01 | 100.0% | 72.6% |
| 8jx6A02 | 2.30.30.780 | Mainly Beta › Roll › SH3 type barrels. › | 0.90 | 66.0 | 5.17e-01 | 84.9% | 39.8% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.86 | 76.0 | 6.96e-01 | 96.2% | 80.6% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.86 | 76.0 | 6.99e-01 | 98.1% | 76.5% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.85 | 78.0 | 6.79e-01 | 100.0% | 72.7% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 73.0 | 6.93e-01 | 94.3% | 87.1% |
| 2lf0A01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.84 | 70.0 | 6.73e-01 | 90.6% | 86.7% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.84 | 72.0 | 5.80e-01 | 98.1% | 50.0% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.84 | 67.0 | 5.91e-01 | 86.8% | 62.7% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 76.0 | 5.05e-01 | 100.0% | 28.3% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 64.0 | 4.55e-01 | 83.0% | 32.2% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.83 | 73.0 | 5.55e-01 | 100.0% | 45.2% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 68.0 | 4.85e-01 | 90.6% | 32.7% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 73.0 | 6.73e-01 | 100.0% | 81.2% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.82 | 67.0 | 5.97e-01 | 88.7% | 64.9% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.82 | 67.0 | 5.93e-01 | 88.7% | 63.2% |
| 2lhrA00 | 1.20.58.1270 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 63.0 | 5.51e-01 | 86.8% | 56.4% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.81 | 71.0 | 4.94e-01 | 98.1% | 62.6% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.80 | 66.0 | 4.76e-01 | 96.2% | 33.3% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.79 | 66.0 | 5.86e-01 | 98.1% | 64.1% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.79 | 69.0 | 6.04e-01 | 100.0% | 64.6% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.79 | 64.0 | 6.17e-01 | 94.3% | 79.7% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 66.0 | 5.37e-01 | 96.2% | 49.5% |
| 4gczA03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.78 | 70.0 | 6.52e-01 | 100.0% | 87.7% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.78 | 69.0 | 4.92e-01 | 98.1% | 38.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 66.0 | 5.39e-01 | 98.1% | 55.9% |
| 2gsqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.77 | 64.0 | 5.07e-01 | 92.5% | 46.3% |
| 1kfdA02 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.76 | 64.0 | 5.88e-01 | 98.1% | 71.8% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.76 | 64.0 | 5.09e-01 | 100.0% | 46.4% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 64.0 | 5.35e-01 | 100.0% | 54.5% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 70.0 | 5.93e-01 | 100.0% | 77.1% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.75 | 63.0 | 5.36e-01 | 92.5% | 59.3% |
| 3kwoA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 67.0 | 4.81e-01 | 100.0% | 72.5% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 53.0 | 5.07e-01 | 77.4% | 65.1% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 61.0 | 5.48e-01 | 98.1% | 81.0% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 60.0 | 5.51e-01 | 100.0% | 74.7% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 61.0 | 4.71e-01 | 100.0% | 42.5% |
| 3o2tA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.72 | 55.0 | 3.45e-01 | 84.9% | 36.2% |
| 1eteA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.71 | 58.0 | 4.28e-01 | 90.6% | 57.5% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 62.0 | 4.88e-01 | 98.1% | 94.3% |
| 2ckoA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.69 | 61.0 | 3.85e-01 | 100.0% | 47.0% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.68 | 55.0 | 5.05e-01 | 98.1% | 68.4% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 58.0 | 5.72e-01 | 98.1% | 91.1% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 48.0 | 4.90e-01 | 79.2% | 84.0% |
| 3kr9A02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 48.0 | 4.60e-01 | 79.2% | 67.2% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.66 | 60.0 | 4.58e-01 | 100.0% | 47.8% |
| 2vx2G02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.64 | 51.0 | 5.06e-01 | 92.5% | 94.5% |
| 6ictA01 | 3.90.1410.10 | Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 1 › set domain protein methyltransferase, domain 1 | 0.63 | 54.0 | 3.36e-01 | 96.2% | 53.0% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3298709 | 605.1.1.141 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N | 0.94 | 89.0 | 6.47e-01 | 100.0% | 42.4% |
| 5071229 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.93 | 85.0 | 6.65e-01 | 100.0% | 50.5% |
| 4952010 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.92 | 86.0 | 7.53e-01 | 100.0% | 70.7% |
| 3608554 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.92 | 83.0 | 5.89e-01 | 100.0% | 35.9% |
| 4539383 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.91 | 67.0 | 7.22e-01 | 77.4% | 91.1% |
| 3218879 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.91 | 77.0 | 7.35e-01 | 92.5% | 80.0% |
| 4405928 | 5086.1.1.196 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX | 0.91 | 82.0 | 7.39e-01 | 100.0% | 74.3% |
| 3503654 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.90 | 82.0 | 6.16e-01 | 100.0% | 44.2% |
| 4966215 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.90 | 81.0 | 5.58e-01 | 100.0% | 31.5% |
| 3900923 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.90 | 82.0 | 6.51e-01 | 100.0% | 53.0% |
| 4952005 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.90 | 82.0 | 7.07e-01 | 100.0% | 66.3% |
| 3927560 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.90 | 81.0 | 7.75e-01 | 100.0% | 86.7% |
| 3595149 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.89 | 74.0 | 7.08e-01 | 90.6% | 78.3% |
| 3989466 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.89 | 80.0 | 4.41e-01 | 100.0% | 8.4% |
| 148414 | 605.4.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › SCAB_CC | 0.89 | 71.0 | 7.42e-01 | 92.5% | 91.8% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.89 | 73.0 | 6.62e-01 | 88.7% | 67.1% |
| 3595146 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.89 | 68.0 | 7.25e-01 | 81.1% | 95.6% |
| 3498656 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.88 | 82.0 | 6.70e-01 | 100.0% | 58.9% |
| 3180530 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.88 | 73.0 | 5.68e-01 | 96.2% | 43.6% |
| 3336158 | 70.3.1.0 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like | 0.88 | 72.0 | 5.12e-01 | 92.5% | 31.8% |
| 5012794 | 4333.1.1.0 ↗ | a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain | 0.88 | 78.0 | 4.65e-01 | 100.0% | 14.6% |
| 4056724 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.88 | 64.0 | 6.87e-01 | 77.4% | 91.1% |
| 3599032 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.87 | 79.0 | 5.05e-01 | 100.0% | 54.3% |
| 5056100 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.87 | 78.0 | 6.86e-01 | 100.0% | 69.3% |
| 4266268 | 192.8.1.376 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36 | 0.87 | 77.0 | 5.49e-01 | 100.0% | 34.7% |
| 3607135 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.87 | 78.0 | 5.70e-01 | 100.0% | 39.3% |
| 4949374 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.87 | 69.0 | 6.40e-01 | 86.8% | 69.2% |
| 3962893 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.87 | 77.0 | 6.35e-01 | 100.0% | 55.8% |
| 3349325 | 5086.1.1.135 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615 | 0.87 | 76.0 | 6.55e-01 | 100.0% | 63.7% |
| 3784740 | 3712.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 | 0.86 | 78.0 | 6.91e-01 | 100.0% | 76.0% |
| 4984327 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.86 | 76.0 | 6.02e-01 | 100.0% | 49.5% |
| 3275930 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.86 | 76.0 | 4.80e-01 | 100.0% | 20.8% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.86 | 75.0 | 4.73e-01 | 100.0% | 20.5% |
| 3361840 | 3796.1.1.0 ↗ | alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain | 0.85 | 60.0 | 6.71e-01 | 75.5% | 97.5% |
| 3715996 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.85 | 68.0 | 6.96e-01 | 84.9% | 90.0% |
| 4033573 | 2005.2.1.1 ↗ | a/b three-layered sandwiches › HUP domain-like › YdcF › YdcF › DUF218 | 0.85 | 76.0 | 4.88e-01 | 100.0% | 23.0% |
| 4638770 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.85 | 59.0 | 4.84e-01 | 71.7% | 42.2% |
| 3959609 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.85 | 75.0 | 6.12e-01 | 100.0% | 54.1% |
| 3409326 | 3930.1.1.6 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD | 0.85 | 76.0 | 5.53e-01 | 100.0% | 38.5% |
| 3726168 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.83 | 70.0 | 5.40e-01 | 90.6% | 56.4% |
| 4942736 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.83 | 76.0 | 5.97e-01 | 100.0% | 53.3% |
| 3917938 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.83 | 72.0 | 4.73e-01 | 100.0% | 24.2% |
| 3469530 | 3274.1.1.1 ↗ | extended segments › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › Ribosomal_S5 | 0.82 | 76.0 | 5.42e-01 | 100.0% | 77.1% |
| 3735658 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.82 | 67.0 | 5.20e-01 | 94.3% | 41.7% |
| 5027487 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.82 | 70.0 | 4.63e-01 | 98.1% | 23.6% |
| 3797833 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.81 | 73.0 | 4.96e-01 | 100.0% | 83.2% |
| 3286299 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.81 | 71.0 | 5.56e-01 | 100.0% | 47.3% |
| None | — | 0.81 | 70.0 | 4.68e-01 | 92.5% | 28.3% | |
| 4655609 | 5060.1.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 | 0.81 | 67.0 | 4.82e-01 | 94.3% | 32.3% |
| 4826095 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.80 | 65.0 | 5.36e-01 | 88.7% | 50.5% |
| 5070891 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.80 | 67.0 | 5.79e-01 | 90.6% | 60.0% |
| 3952510 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.80 | 69.0 | 6.24e-01 | 100.0% | 70.7% |
| 4671 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.79 | 70.0 | 5.50e-01 | 100.0% | 48.2% |
| 3898383 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.78 | 67.0 | 5.14e-01 | 100.0% | 42.4% |
| 5040591 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.77 | 64.0 | 5.33e-01 | 90.6% | 63.3% |
| 3791628 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.77 | 68.0 | 4.95e-01 | 100.0% | 36.6% |
| 3808 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.76 | 66.0 | 5.34e-01 | 100.0% | 50.0% |
| 1821875 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.76 | 61.0 | 5.91e-01 | 94.3% | 79.7% |
| 4017831 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.75 | 65.0 | 4.61e-01 | 96.2% | 70.3% |
| 3505389 | 2004.1.1.144 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 | 0.75 | 64.0 | 3.83e-01 | 96.2% | 14.5% |
| 4270097 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.73 | 60.0 | 4.85e-01 | 96.2% | 46.7% |
| 3401938 | 3602.1.1.14 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › DUF733 | 0.70 | 57.0 | 5.22e-01 | 96.2% | 72.0% |
| 4942605 | 3922.1.1.356 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › AI-2E_transport | 0.63 | 54.0 | 4.06e-01 | 96.2% | 42.2% |
D4
medium
residues 330-426
Domain cluster:
rep: JF974315.1__AGN38697.1__RHYG_00028__00028__D233-310
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2a6hF01 | 1.20.120.1810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 54.0 | 4.31e-01 | 87.6% | 42.1% |
| 1bdp002 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.69 | 37.0 | 3.55e-01 | 92.8% | 45.9% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 48.0 | 4.82e-01 | 94.8% | 78.0% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.63 | 50.0 | 5.37e-01 | 84.5% | 100.0% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.62 | 50.0 | 4.39e-01 | 94.8% | 58.9% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.61 | 46.0 | 5.02e-01 | 89.7% | 95.1% |
| 2aplA01 | 1.10.8.330 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.61 | 41.0 | 4.79e-01 | 76.3% | 100.0% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.61 | 43.0 | 4.54e-01 | 78.4% | 82.4% |
| 2y1eA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.61 | 44.0 | 4.61e-01 | 78.4% | 82.8% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 50.0 | 4.36e-01 | 88.7% | 62.5% |
| 2yyiA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 51.0 | 3.95e-01 | 91.8% | 52.6% |
| 6umqA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.60 | 45.0 | 4.25e-01 | 79.4% | 100.0% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 47.0 | 4.98e-01 | 88.7% | 95.3% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.60 | 44.0 | 4.31e-01 | 77.3% | 74.3% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 43.0 | 4.52e-01 | 79.4% | 83.0% |
| 3vkgA09 | 1.20.920.30 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.59 | 45.0 | 3.99e-01 | 83.5% | 54.9% |
| 2e9fB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.59 | 43.0 | 4.41e-01 | 77.3% | 82.3% |
| 5z7cA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.59 | 45.0 | 3.75e-01 | 82.5% | 84.1% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 49.0 | 4.25e-01 | 92.8% | 62.7% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.58 | 44.0 | 4.60e-01 | 90.7% | 90.8% |
| 2lyiA01 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.58 | 44.0 | 3.83e-01 | 80.4% | 52.7% |
| 5yixA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.58 | 43.0 | 3.05e-01 | 87.6% | 23.8% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.57 | 45.0 | 3.46e-01 | 83.5% | 40.0% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 49.0 | 4.30e-01 | 92.8% | 71.1% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 42.0 | 4.37e-01 | 80.4% | 82.4% |
| 3fedA03 | 1.20.930.40 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain | 0.57 | 45.0 | 3.96e-01 | 88.7% | 82.6% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.57 | 43.0 | 4.68e-01 | 87.6% | 98.8% |
| 1kxpD02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.55 | 42.0 | 4.36e-01 | 85.6% | 87.5% |
| 3rh9A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 39.0 | 2.90e-01 | 74.2% | 66.1% |
| 4zqeA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.55 | 42.0 | 4.28e-01 | 80.4% | 84.4% |
| 1sigA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.51 | 45.0 | 3.16e-01 | 96.9% | 44.9% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3192559 | 148.1.3.216 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF7069 | 0.75 | 52.0 | 5.54e-01 | 89.7% | 81.2% |
| 5066085 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.73 | 49.0 | 4.94e-01 | 87.6% | 69.5% |
| 4024271 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.69 | 61.0 | 5.37e-01 | 93.8% | 85.2% |
| 4032765 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.69 | 47.0 | 4.45e-01 | 89.7% | 59.1% |
| 3389526 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.68 | 62.0 | 6.22e-01 | 99.0% | 100.0% |
| 4452096 | 142.1.1.1 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r1_2,Sigma70_r2 | 0.68 | 50.0 | 3.98e-01 | 87.6% | 39.0% |
| 4681325 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.64 | 51.0 | 5.54e-01 | 86.6% | 100.0% |
| 4033040 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.64 | 50.0 | 5.46e-01 | 91.8% | 100.0% |
| 3360961 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.64 | 51.0 | 4.15e-01 | 88.7% | 46.9% |
| 4927047 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.64 | 47.0 | 5.25e-01 | 77.3% | 100.0% |
| 4484001 | 142.1.1.4 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2,Sigma70_ner | 0.63 | 47.0 | 3.25e-01 | 87.6% | 23.0% |
| 4269761 | 142.1.1.1 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r1_2,Sigma70_r2 | 0.62 | 51.0 | 4.07e-01 | 88.7% | 44.7% |
| 4478129 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.62 | 43.0 | 4.50e-01 | 74.2% | 76.7% |
| 4080592 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.62 | 43.0 | 4.47e-01 | 79.4% | 76.7% |
| 4631806 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.62 | 44.0 | 3.46e-01 | 82.5% | 35.5% |
| None | — | 0.62 | 50.0 | 4.27e-01 | 87.6% | 55.3% | |
| 3372157 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.62 | 47.0 | 4.99e-01 | 86.6% | 91.8% |
| 5057501 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.62 | 44.0 | 4.36e-01 | 73.2% | 97.0% |
| 5045176 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.61 | 54.0 | 5.33e-01 | 96.9% | 100.0% |
| 4462943 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.61 | 43.0 | 4.45e-01 | 80.4% | 77.8% |
| 4144086 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.61 | 43.0 | 4.26e-01 | 77.3% | 70.0% |
| 4024626 | 545.1.2.2 ↗ | alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain › ETRAMP | 0.61 | 50.0 | 4.34e-01 | 87.6% | 74.5% |
| 4076702 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.61 | 43.0 | 4.28e-01 | 80.4% | 71.0% |
| 4164998 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.61 | 44.0 | 4.39e-01 | 77.3% | 73.0% |
| 4159969 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.60 | 46.0 | 4.48e-01 | 80.4% | 74.3% |
| 4031203 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.59 | 46.0 | 4.97e-01 | 86.6% | 100.0% |
| 3190824 | 166.1.1.0 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C | 0.59 | 43.0 | 4.85e-01 | 80.4% | 100.0% |
| 3336154 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.59 | 52.0 | 4.68e-01 | 94.8% | 78.5% |
| 4225289 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.59 | 45.0 | 4.25e-01 | 80.4% | 73.0% |
| 4033046 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.57 | 42.0 | 4.64e-01 | 81.4% | 100.0% |
| 4133362 | 632.11.1.6 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › Yae1_N | 0.57 | 47.0 | 4.75e-01 | 90.7% | 94.7% |
| 4465300 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.57 | 45.0 | 4.65e-01 | 86.6% | 94.4% |
| 4671383 | 4177.1.1.9 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom | 0.56 | 48.0 | 3.59e-01 | 94.8% | 95.5% |
| 3950299 | 166.1.1.1 ↗ | alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C | 0.56 | 45.0 | 4.23e-01 | 85.6% | 75.7% |
| 3957651 | 191.1.1.11 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_7 | 0.55 | 47.0 | 4.26e-01 | 95.9% | 71.1% |
| 3676572 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.55 | 45.0 | 3.69e-01 | 87.6% | 49.1% |
| 4513974 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.55 | 41.0 | 3.84e-01 | 84.5% | 63.3% |
| 3658108 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.55 | 46.0 | 4.05e-01 | 91.8% | 80.0% |
| 4981517 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.55 | 45.0 | 3.76e-01 | 89.7% | 85.3% |
| 4349095 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.55 | 40.0 | 3.79e-01 | 83.5% | 64.3% |
| 4258677 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.55 | 40.0 | 3.07e-01 | 83.5% | 32.9% |
| 3865887 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.55 | 43.0 | 4.57e-01 | 83.5% | 95.3% |
| 5035870 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.54 | 46.0 | 4.54e-01 | 93.8% | 93.3% |
| 3955772 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.53 | 43.0 | 4.51e-01 | 88.7% | 97.8% |
| 3594690 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.51 | 40.0 | 3.06e-01 | 82.5% | 50.2% |
D5
medium
residues 427-486
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3vouB00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 60.0 | 4.56e-01 | 80.0% | 37.5% |
| 5zr4A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.74 | 54.0 | 4.56e-01 | 78.3% | 52.9% |
| 2raeA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.72 | 55.0 | 4.22e-01 | 83.3% | 38.0% |
| 4didB01 | 1.20.58.450 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cell division control protein 42 homolog | 0.69 | 58.0 | 4.57e-01 | 88.3% | 79.8% |
| 1c1dA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.62 | 53.0 | 3.74e-01 | 100.0% | 48.5% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 3.74e-01 | 75.0% | 56.4% |
| 4d3pA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.59 | 48.0 | 3.56e-01 | 86.7% | 86.4% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 49.0 | 4.31e-01 | 100.0% | 88.0% |
| 3c24A02 | 1.10.3640.10 | Mainly Alpha › Orthogonal Bundle › putative oxidoreductase fold › Semialdehyde dehydrogenase-like, C-terminal | 0.59 | 45.0 | 3.90e-01 | 91.7% | 52.0% |
| 3rosA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.59 | 46.0 | 3.03e-01 | 88.3% | 73.1% |
| 3vz3A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.59 | 45.0 | 3.05e-01 | 88.3% | 71.5% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.58 | 43.0 | 4.24e-01 | 85.0% | 74.6% |
| 2j6lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.58 | 49.0 | 3.15e-01 | 95.0% | 93.7% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 44.0 | 4.22e-01 | 81.7% | 78.9% |
| 4i8qA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.57 | 44.0 | 2.90e-01 | 88.3% | 66.6% |
| 3ju8A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.57 | 46.0 | 3.06e-01 | 95.0% | 65.5% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 40.0 | 3.05e-01 | 75.0% | 61.7% |
| 2hg2A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 42.0 | 2.78e-01 | 85.0% | 64.3% |
| 1ez0B01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 44.0 | 2.90e-01 | 95.0% | 67.9% |
| 3r64A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 42.0 | 2.74e-01 | 85.0% | 65.6% |
| 3rh9A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 41.0 | 2.79e-01 | 100.0% | 95.2% |
| 6fjxA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 42.0 | 2.80e-01 | 96.7% | 95.6% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3942326 | 191.1.1.48 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 | 0.83 | 60.0 | 4.53e-01 | 76.7% | 34.1% |
| 3503552 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.82 | 62.0 | 4.64e-01 | 80.0% | 36.0% |
| 4142281 | 105.1.1.55 ↗ | alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › Latarcin | 0.81 | 56.0 | 4.75e-01 | 71.7% | 46.8% |
| 4971975 | 3456.1.1.0 ↗ | extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A | 0.81 | 63.0 | 4.86e-01 | 86.7% | 40.0% |
| 4881755 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.79 | 58.0 | 4.87e-01 | 88.3% | 47.0% |
| 3929290 | 614.1.1.0 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain | 0.78 | 55.0 | 5.29e-01 | 85.0% | 64.3% |
| 4984680 | 3962.1.1.1 ↗ | alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit › HsdM_N | 0.74 | 65.0 | 4.66e-01 | 96.7% | 37.6% |
| 3655029 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.74 | 65.0 | 4.28e-01 | 98.3% | 24.8% |
| 5043797 | 3542.1.1.1 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin | 0.73 | 56.0 | 3.65e-01 | 96.7% | 18.5% |
| 3693616 | 604.9.1.8 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › DUF6594 | 0.72 | 48.0 | 4.40e-01 | 70.0% | 52.5% |
| 3379640 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.71 | 64.0 | 4.04e-01 | 98.3% | 21.5% |
| 4973801 | 7523.1.1.22 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › ABC2_membrane_3 | 0.65 | 56.0 | 4.26e-01 | 93.3% | 96.3% |
| 4003083 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.65 | 58.0 | 4.38e-01 | 96.7% | 51.1% |
| 3589629 | 307.1.1.3 ↗ | a+b two layers › Hedgehog/DD-peptidase › Hedgehog/DD-peptidase › Hedgehog/DD-peptidase › VanY | 0.65 | 55.0 | 3.84e-01 | 95.0% | 72.4% |
| 4941766 | 7011.1.1.5 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O_anti_polymase | 0.61 | 50.0 | 3.12e-01 | 96.7% | 90.5% |
| 3598688 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.59 | 45.0 | 3.29e-01 | 83.3% | 81.8% |
| 3407914 | 632.8.1.28 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › SHCBP_N | 0.57 | 40.0 | 3.66e-01 | 90.0% | 55.0% |