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LEF-2

Euk-Vir

Urbanus_proteus_nucleopolyhedrovirus

LEF-2__YP_009250088__Urbanus_proteus_nucleopolyhedrovirus__1675866

Identity

Accession:
YP_009250088 ↗
Protein ID:
LEF-2
Kingdom:
euk

Quality

72.9 mean pLDDT

Taxonomy

Naldaviricetes› Lefavirales› Baculoviridae› Alphabaculovirus› Urbanus_proteus_nucleopolyhedrovirus

TaxID: 1675866

Cluster

View cluster (32 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 10-66
PDB
Domain cluster: rep: lef2__YP_009666652__Oxyplax_ochracea_nucleopolyhedrovirus__2083176__D13-67
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03041.21 best Baculo_LEF-2 34.1 3.40e-08 86.0% 28.3%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4y4mC00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.68 55.0 3.62e-01 93.0% 32.2%
4k22B01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.67 55.0 3.63e-01 93.0% 33.1%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 45.0 3.64e-01 93.0% 37.6%
2jmlA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.64 48.0 4.28e-01 80.7% 71.6%
4bpxD00 1.20.930.80 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.63 50.0 3.42e-01 89.5% 30.5%
1l8rA00 3.10.260.20 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › Ski 0.60 52.0 4.36e-01 100.0% 93.1%
2v5tA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 45.0 3.94e-01 86.0% 68.1%
2kvvA00 1.10.1660.60 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › Putative excisionased domain DUF1233 0.59 43.0 4.01e-01 82.5% 89.7%
3dgpB00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.59 42.0 4.17e-01 78.9% 87.3%
2wb6A00 3.90.1150.90 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.58 48.0 3.85e-01 93.0% 56.1%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 41.0 3.49e-01 93.0% 45.7%
2e9xB01 3.40.5.50 Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › 0.57 42.0 4.08e-01 80.7% 72.7%
3kvqA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 43.0 3.95e-01 89.5% 70.7%
2fwrA01 3.40.1170.30 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › 0.56 40.0 4.06e-01 94.7% 80.7%
2vd3A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 40.0 3.19e-01 80.7% 75.0%
4u7mA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 41.0 3.64e-01 87.7% 64.9%
3dgpA00 3.30.70.2610 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 39.0 3.83e-01 80.7% 88.7%
6mrc100 2.30.33.40 Mainly Beta › Roll › 10 Kd Chaperonin, Protein Cpn10; Chain O › GroES chaperonin 0.53 45.0 3.75e-01 96.5% 97.0%
2zhgA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.52 41.0 3.35e-01 100.0% 43.8%
4oc9A02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 40.0 3.16e-01 89.5% 85.4%
3euhC02 1.10.10.2260 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MukE-like family, C-terminal domain 0.52 38.0 3.16e-01 80.7% 80.6%
2pg4A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 42.0 3.73e-01 98.2% 76.9%
1ga3A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 40.0 3.17e-01 84.2% 69.9%
5d8cA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.51 43.0 3.46e-01 100.0% 45.2%
7xoiD01 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.51 36.0 3.05e-01 78.9% 82.2%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3916205 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.69 58.0 3.77e-01 93.0% 33.2%
3402914 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.67 50.0 4.52e-01 80.7% 74.7%
3493388 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 44.0 4.09e-01 75.4% 84.0%
3700514 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.61 50.0 4.00e-01 93.0% 98.3%
4997694 3877.1.2.1 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › DUF106 › EMC3_TMCO1 0.61 52.0 3.76e-01 100.0% 89.7%
3729291 108.1.1.1 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1 0.60 47.0 3.94e-01 87.7% 78.1%
3313495 2003.1.5.185 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF28720 0.60 50.0 3.78e-01 100.0% 56.8%
3465161 2003.1.5.185 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF28720 0.59 49.0 3.62e-01 100.0% 55.3%
4027679 192.2.1.2 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.58 43.0 3.55e-01 93.0% 43.8%
3783976 192.2.1.2 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.57 43.0 3.70e-01 94.7% 51.1%
4991995 3696.1.1.2 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.57 44.0 4.31e-01 94.7% 78.5%
4315725 295.1.1.12 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › UPF0231 0.57 49.0 3.80e-01 94.7% 75.8%
4025308 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.57 41.0 3.65e-01 80.7% 83.3%
3938777 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.56 43.0 2.64e-01 94.7% 80.4%
3744768 213.1.1.0 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.55 46.0 3.76e-01 100.0% 65.8%
4355700 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.55 45.0 2.89e-01 94.7% 67.4%
3409500 3696.1.1.1 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.55 45.0 4.27e-01 94.7% 81.4%
4955746 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.55 43.0 3.92e-01 93.0% 74.1%
5059159 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.55 44.0 3.59e-01 91.2% 59.3%
3620127 3696.1.1.1 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.54 44.0 3.99e-01 93.0% 71.2%
3938950 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.54 46.0 3.46e-01 100.0% 58.0%
4955387 3696.1.1.2 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.54 37.0 3.90e-01 94.7% 86.0%
3926287 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.54 42.0 2.72e-01 94.7% 72.6%
3470093 3696.1.1.1 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.53 42.0 4.16e-01 94.7% 86.2%
3551485 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.53 42.0 2.69e-01 91.2% 79.4%
3501383 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.53 41.0 2.67e-01 93.0% 77.5%
3998582 3696.1.1.1 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.53 42.0 4.01e-01 93.0% 80.0%
4636556 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.53 38.0 2.43e-01 75.4% 20.0%
4962546 2003.1.5.33 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0146 0.52 37.0 2.91e-01 77.2% 82.1%
4997049 3696.1.1.0 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related 0.52 41.0 3.90e-01 94.7% 75.7%
2631918 3696.1.1.2 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.52 37.0 3.72e-01 94.7% 75.9%
4066114 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.51 38.0 2.47e-01 78.9% 19.3%
5050281 304.120.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.51 36.0 3.29e-01 75.4% 86.3%
4397567 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.51 37.0 2.45e-01 78.9% 20.0%
4341158 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.51 42.0 3.14e-01 96.5% 63.8%
2631980 3696.1.1.2 ↗ a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.51 40.0 3.71e-01 91.2% 79.2%
4433461 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.51 40.0 2.67e-01 94.7% 76.8%
4683052 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.51 37.0 2.33e-01 77.2% 17.6%
D2 high residues 88-199
PDB
Domain cluster: rep: LEF-2__YP_009552671__Operophtera_brumata_nucleopolyhedrovirus__1046267__D88-194
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03041.21 best Baculo_LEF-2 92.3 4.00e-26 81.2% 57.2%