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LEF-4

Euk-Vir

Choristoneura_rosaceana_nucleopolyhedrovirus

LEF-4__YP_008378417__Choristoneura_rosaceana_nucleopolyhedrovirus__58094

Identity

Accession:
YP_008378417 ↗
Protein ID:
LEF-4
Kingdom:
euk

Quality

81.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 214-391
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 213.2 1.00e-62 100.0% 39.8%
D2 high residues 396-446
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 44.6 1.50e-11 100.0% 11.4%
D3 medium residues 1-16_60-92_170-207
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2j5aA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.67 46.0 4.35e-01 71.3% 96.2%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 40.0 3.77e-01 70.1% 84.1%
1tz0B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 38.0 3.68e-01 70.1% 96.9%
4y6iA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 3.59e-01 70.1% 83.5%
1t82A00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.55 34.0 2.95e-01 90.8% 38.7%
2v0uA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 43.0 3.67e-01 87.4% 91.1%
6kf9G01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 27.0 2.81e-01 83.9% 50.0%
4ozjA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.50e-01 71.3% 83.7%
1ekrA00 3.30.70.640 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Molybdopterin cofactor biosynthesis C (MoaC) domain 0.53 38.0 3.23e-01 74.7% 92.3%
5egjA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.53 42.0 3.45e-01 87.4% 62.3%
4llfD02 2.60.40.4030 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 36.0 3.28e-01 73.6% 65.0%
6ofsA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 39.0 3.06e-01 81.6% 63.6%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3495445 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.69 52.0 3.36e-01 79.3% 27.0%
4029744 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.67 46.0 3.83e-01 70.1% 97.9%
4411078 304.12.1.1 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › Ribosomal_S6 0.65 45.0 4.32e-01 70.1% 99.0%
3255400 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.63 32.0 2.04e-01 83.9% 10.8%
3970088 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 43.0 4.19e-01 71.3% 96.8%
4936511 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.62 42.0 3.93e-01 70.1% 96.4%
3971017 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.61 41.0 3.83e-01 70.1% 89.1%
3271482 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.59 45.0 3.32e-01 81.6% 92.5%
4002360 11.2.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.52 39.0 2.92e-01 82.8% 97.1%
4103142 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.51 29.0 3.00e-01 75.9% 57.5%
5078578 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.51 39.0 3.36e-01 82.8% 91.0%
D4 medium residues 17-59_93-151
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05098.19 best LEF-4 34.4 1.90e-08 56.9% 12.5%
PF05098.19 LEF-4 40.5 2.60e-10 47.1% 9.2%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qrdB01 2.20.25.290 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.59 24.0 3.50e-01 76.5% 97.3%
3l5iA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 38.0 4.07e-01 87.3% 78.4%
4inaA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.56 44.0 3.56e-01 84.3% 96.4%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.55 32.0 3.59e-01 74.5% 77.0%
1ye9A02 2.40.470.10 Mainly Beta › Beta Barrel › catalase hpii fold › catalase hpii domain 0.54 36.0 3.55e-01 93.1% 61.6%
3f6gA01 3.30.160.740 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 25.0 3.06e-01 82.4% 70.7%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.52 32.0 3.45e-01 99.0% 74.7%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.52 27.0 3.05e-01 86.3% 63.3%
5jtwA05 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.52 41.0 3.88e-01 84.3% 90.9%
2rqlA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.51 27.0 2.87e-01 90.2% 52.6%
1oo0A00 3.30.1560.10 Alpha Beta › 2-Layer Sandwich › Mago nashi protein › Mago nashi 0.51 39.0 3.48e-01 81.4% 88.9%
4depC02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 36.0 3.61e-01 90.2% 72.5%
2l7eA00 2.60.40.1970 Mainly Beta › Sandwich › Immunoglobulin-like › YEATS domain 0.50 33.0 3.12e-01 78.4% 54.5%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5052285 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.62 38.0 3.77e-01 98.0% 58.1%
3904085 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 39.0 4.53e-01 87.3% 90.0%
4931364 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 29.0 3.08e-01 79.4% 47.8%
3486954 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 34.0 3.70e-01 76.5% 71.8%
4014375 3256.1.1.0 a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain 0.56 29.0 3.70e-01 83.3% 96.0%
4026006 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.56 33.0 3.62e-01 76.5% 72.5%
3590547 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.56 27.0 2.54e-01 84.3% 33.8%
4961043 11.1.4.23 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › CarboxypepD_reg 0.54 36.0 3.86e-01 91.2% 78.9%
5061444 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.54 33.0 3.61e-01 88.2% 74.1%
3552986 11.1.1.275 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IL3Ra_N 0.53 37.0 4.06e-01 73.5% 94.1%
5036579 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.52 36.0 2.72e-01 80.4% 29.4%
3603056 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 28.0 3.19e-01 86.3% 68.0%
5076824 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 46.0 3.20e-01 100.0% 60.8%
3404941 220.1.1.15 beta barrels › PH domain-like › PH domain-like › PH domain-like › BBL5 0.52 40.0 3.38e-01 100.0% 49.4%
5067357 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.51 34.0 2.65e-01 80.4% 30.0%