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LK985322.1__CDW17183.1__X__00002

Bact-Vir

LK985322.1__CDW17183.1__X__00002

Identity

Accession:
LK985322 ↗
Kingdom:
phage

Quality

72.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 289-437
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF17289.9 best Terminase_6C 23.7 5.80e-05 86.6% 63.9%
PF22530.3 Terminase-T7_RNaseH-like 39.4 8.70e-10 72.5% 96.3%
D2 medium residues 16-79_232-262
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h1tA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 47.0 3.87e-01 72.6% 95.9%
2oyhA00 1.20.5.50 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 28.0 3.38e-01 72.6% 62.5%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964368 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.90 86.0 6.00e-01 100.0% 93.6%
D3 medium residues 80-231
PDB
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a1vA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 46.0 4.89e-01 94.7% 76.3%
2p6nA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 56.0 5.53e-01 100.0% 81.9%
5supC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 57.0 5.09e-01 100.0% 67.6%
1pjrA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 55.0 5.00e-01 100.0% 69.5%
3s7zA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.64 42.0 4.56e-01 96.1% 79.8%
4ljyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 54.0 5.02e-01 100.0% 71.7%
2yv4A00 3.40.50.11030 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Threonylcarbamoyl-AMP synthase, C-terminal domain 0.63 32.0 3.78e-01 100.0% 68.6%
3i5xA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 58.0 4.92e-01 100.0% 64.0%
2zskA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 40.0 4.51e-01 96.7% 84.5%
2kbeA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 53.0 4.61e-01 96.7% 61.5%
7nadx01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 57.0 5.07e-01 100.0% 72.4%
2gk6A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 51.0 4.15e-01 96.7% 50.2%
3rc3A04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 49.0 5.02e-01 95.4% 89.0%
2a3nA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.60 40.0 3.94e-01 94.7% 61.7%
6fwrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 55.0 5.01e-01 100.0% 82.0%
6jdrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 4.41e-01 100.0% 78.3%
7r7jA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 51.0 4.75e-01 96.1% 74.7%
3gu3A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 48.0 4.66e-01 98.7% 78.4%
1y8cA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 46.0 4.36e-01 100.0% 68.8%
2cvhA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 53.0 4.75e-01 100.0% 74.8%
2vl7A03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 4.80e-01 100.0% 79.8%
3pvzB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 52.0 4.20e-01 100.0% 70.3%
1zd9A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 4.79e-01 99.3% 84.3%
4dkjA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 52.0 4.17e-01 100.0% 63.5%
3mq2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 46.0 4.12e-01 100.0% 62.8%
1onfA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 31.0 3.44e-01 90.8% 66.9%
8jx6B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 47.0 4.28e-01 96.7% 69.5%
2fiqA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 42.0 3.44e-01 80.9% 68.8%
3fdgA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 47.0 3.68e-01 94.1% 92.9%
5cygB00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.54 44.0 3.66e-01 88.2% 78.9%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.54 43.0 4.21e-01 98.7% 77.0%
3lcvB02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 44.0 4.01e-01 100.0% 65.3%
4i1sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 36.0 4.06e-01 86.8% 88.8%
3qpbF00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.54 44.0 3.70e-01 86.2% 81.3%
2xrfC00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.53 44.0 3.59e-01 88.2% 76.9%
1kjwA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 36.0 3.93e-01 84.9% 86.0%
1h1lD03 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.53 34.0 3.58e-01 94.7% 71.4%
2h00B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 4.02e-01 100.0% 66.2%
1g01A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 46.0 3.57e-01 96.7% 93.8%
3w5jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 4.10e-01 97.4% 71.6%
3czpB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 42.0 3.82e-01 86.8% 76.5%
4iqyB00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.52 46.0 4.09e-01 97.4% 94.1%
3qhqB01 3.40.50.11940 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 35.0 3.55e-01 94.7% 69.1%
3al2A01 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.52 38.0 4.12e-01 98.0% 93.5%
2okcA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 47.0 3.73e-01 100.0% 64.4%
5ailA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.52 46.0 4.36e-01 98.7% 89.4%
3ccfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 48.0 4.07e-01 100.0% 63.9%
3a52A01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.51 46.0 3.68e-01 100.0% 64.8%
4e4tB01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 35.0 3.98e-01 90.8% 94.7%
4umlA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.50 44.0 4.10e-01 98.7% 99.5%
3r74B02 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.50 43.0 4.04e-01 97.4% 74.0%
1yd9B00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.50 45.0 4.23e-01 99.3% 87.7%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002633 2004.1.1.99 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N 0.93 80.0 6.48e-01 100.0% 51.9%
5083088 2004.1.1.99 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N 0.90 87.0 6.81e-01 100.0% 55.1%
3964368 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.89 85.0 6.77e-01 100.0% 56.2%
4527807 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.86 83.0 6.27e-01 100.0% 49.2%
5080206 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.81 76.0 6.05e-01 100.0% 57.2%
3520006 2004.1.1.186 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.70 51.0 4.51e-01 100.0% 53.0%
4029484 2004.1.1.186 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.69 57.0 4.42e-01 100.0% 41.9%
4648604 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.68 57.0 5.28e-01 100.0% 70.7%
3391572 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.67 58.0 5.04e-01 100.0% 62.2%
3829594 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.65 54.0 4.42e-01 100.0% 50.8%
3605703 2004.1.1.457 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C, ERCC3_RAD25_C 0.63 54.0 4.52e-01 100.0% 55.9%
3685788 2003.1.6.6 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Misat_Tub_SegII+Tubulin_3 0.63 50.0 4.06e-01 85.5% 86.4%
3804230 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.63 58.0 4.97e-01 100.0% 65.1%
3391247 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.63 59.0 4.37e-01 100.0% 51.8%
3743865 2004.1.1.535 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Utp25_C, UTP25_NTPase-like 0.62 58.0 3.80e-01 100.0% 37.5%
4420366 2004.1.1.195 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C 0.61 56.0 4.31e-01 100.0% 88.8%
3962994 2004.1.1.364 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.61 55.0 3.88e-01 98.0% 39.1%
3725956 2004.1.1.186 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.61 55.0 4.46e-01 100.0% 52.3%
3261673 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.61 51.0 4.77e-01 100.0% 72.1%
3423525 2004.1.1.186 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.60 48.0 4.30e-01 96.7% 60.5%
3993078 2003.1.5.73 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.60 51.0 4.36e-01 100.0% 57.9%
4205275 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.60 55.0 4.47e-01 100.0% 65.6%
3690873 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.59 54.0 4.68e-01 96.7% 85.9%
4218528 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.59 53.0 4.81e-01 100.0% 74.0%
3243146 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 51.0 4.54e-01 95.4% 66.0%
3642836 2004.1.1.33 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C,RecQ_Zn_bind 0.59 53.0 4.81e-01 100.0% 74.0%
5049322 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 51.0 4.73e-01 95.4% 75.3%
1117603 2004.1.1.194 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 0.58 50.0 4.80e-01 100.0% 79.8%
3576652 2003.1.5.73 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 0.58 49.0 3.92e-01 100.0% 46.4%
4271962 2003.1.6.6 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Misat_Tub_SegII+Tubulin_3 0.58 52.0 4.30e-01 98.0% 100.0%
4647631 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.58 50.0 4.64e-01 98.0% 73.7%
5024224 2004.1.1.79 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin 0.57 46.0 4.25e-01 84.2% 85.3%
4926848 2003.1.5.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase 0.57 52.0 4.11e-01 100.0% 76.5%
4616152 2004.1.1.233 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2 0.57 49.0 4.66e-01 99.3% 77.8%
3471078 2007.5.1.0 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase 0.57 51.0 4.21e-01 99.3% 71.6%
4434568 102.1.1.6 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › Methyltransf_5 0.57 50.0 4.54e-01 100.0% 72.2%
3705020 2004.1.1.186 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 0.56 52.0 4.17e-01 100.0% 59.9%
3404782 2004.1.1.240 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Utp25_C 0.56 52.0 4.74e-01 99.3% 79.0%
4959285 2003.1.5.62 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.56 51.0 3.99e-01 100.0% 68.3%
1902249 2003.1.5.142 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NpmA 0.56 46.0 4.12e-01 100.0% 62.8%
3838571 2003.1.5.46 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.56 51.0 4.43e-01 100.0% 73.9%
4198622 2003.1.5.17 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_5 0.56 50.0 4.47e-01 100.0% 70.0%
5025713 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.56 38.0 3.34e-01 95.4% 48.4%
3201114 2004.1.1.230 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Tsr1_G-like 0.55 48.0 4.33e-01 100.0% 68.8%
3405400 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.55 50.0 4.43e-01 100.0% 78.2%
4929082 2004.1.1.260 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MEDS 0.55 50.0 4.36e-01 100.0% 74.8%
5066797 2004.1.1.1217 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF7125 0.55 50.0 4.20e-01 100.0% 73.3%
3404463 2011.2.1.1 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PNP_UDP_1 0.55 45.0 3.60e-01 88.2% 73.5%
4064859 2003.1.5.46 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.55 49.0 4.23e-01 100.0% 63.0%
5042220 7575.1.1.0 a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like 0.54 49.0 4.36e-01 100.0% 95.9%
5075804 2484.1.1.337 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RRXRR 0.54 39.0 3.62e-01 84.2% 59.5%
3675137 2003.1.5.28 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase 0.53 43.0 4.05e-01 88.2% 70.3%
3491069 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.52 47.0 4.30e-01 98.7% 91.7%
9393 2003.1.5.151 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.52 48.0 4.08e-01 100.0% 67.5%
2171605 7529.1.1.1 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › Macro 0.52 46.0 4.28e-01 98.7% 83.8%
4629764 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.52 47.0 4.26e-01 100.0% 74.3%
416399 2007.1.1.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase 0.52 45.0 3.98e-01 99.3% 63.8%
4022019 7529.1.1.5 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like › PARG_cat_microb 0.51 46.0 3.70e-01 100.0% 60.3%
3197675 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 44.0 4.00e-01 92.8% 83.5%
3269455 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.51 38.0 3.26e-01 78.9% 98.1%
3502580 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.51 46.0 4.32e-01 97.4% 88.6%
3925883 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.51 45.0 3.58e-01 98.0% 82.3%
4120064 2003.1.5.62 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.50 45.0 3.74e-01 100.0% 69.1%
D4 medium residues 453-532_753-799
PDB
D5 medium residues 533-621
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oo2A00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.74 41.0 4.42e-01 93.3% 64.5%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 44.0 4.12e-01 100.0% 50.0%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.70 43.0 3.89e-01 97.8% 46.2%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.69 43.0 4.35e-01 98.9% 61.5%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.69 43.0 4.10e-01 96.6% 53.8%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 38.0 3.91e-01 93.3% 56.5%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.67 40.0 3.91e-01 94.4% 54.7%
1hqoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 40.0 3.56e-01 100.0% 42.0%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 39.0 3.81e-01 91.0% 55.2%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 43.0 4.18e-01 100.0% 62.2%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 50.0 4.00e-01 88.8% 81.7%
3tjmA02 1.10.1470.20 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2 0.60 46.0 4.58e-01 91.0% 82.2%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 50.0 4.04e-01 92.1% 78.1%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 43.0 4.57e-01 77.5% 100.0%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 48.0 3.89e-01 89.9% 83.7%
2kj8A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.58 47.0 4.31e-01 88.8% 74.6%
2katA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 41.0 3.78e-01 76.4% 77.4%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 47.0 3.97e-01 92.1% 85.7%
1z19A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.56 46.0 4.48e-01 87.6% 85.0%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 36.0 2.94e-01 98.9% 31.0%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 45.0 3.91e-01 87.6% 90.6%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.54 48.0 4.02e-01 100.0% 58.7%
8a3tD01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 40.0 2.72e-01 79.8% 79.6%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 36.0 3.87e-01 83.1% 81.3%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 43.0 3.26e-01 85.4% 72.2%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.53 38.0 3.32e-01 75.3% 92.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 48.0 3.91e-01 100.0% 56.5%
3vibA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 41.0 3.18e-01 84.3% 45.1%
5jj6B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 39.0 3.82e-01 80.9% 92.7%
4nt1A00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.51 46.0 3.57e-01 100.0% 54.5%
1fnnB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 39.0 3.73e-01 80.9% 83.5%
1sqgA01 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.50 38.0 3.37e-01 84.3% 68.8%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4141009 604.12.1.115 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF26206 0.75 48.0 4.31e-01 100.0% 48.3%
3257705 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.73 47.0 4.66e-01 100.0% 62.1%
4942736 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 47.0 4.49e-01 100.0% 58.1%
4393241 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.69 47.0 4.53e-01 100.0% 62.0%
4359404 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.69 44.0 3.85e-01 100.0% 43.8%
4216064 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.68 43.0 3.82e-01 100.0% 44.2%
4393414 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.68 44.0 3.96e-01 100.0% 47.6%
3593230 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 44.0 3.81e-01 100.0% 42.9%
3602989 5054.1.1.68 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport 0.67 60.0 4.23e-01 98.9% 33.7%
4953656 5054.1.1.68 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport 0.67 59.0 4.79e-01 98.9% 53.1%
4975860 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.67 44.0 4.57e-01 95.5% 71.8%
3402889 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 50.0 3.86e-01 78.7% 75.3%
4048768 5054.1.1.68 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport 0.66 58.0 4.04e-01 98.9% 30.4%
5035991 3567.1.1.112 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport 0.65 58.0 4.78e-01 98.9% 54.4%
3511230 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.65 39.0 3.90e-01 93.3% 55.8%
2163984 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.63 37.0 3.26e-01 97.8% 40.6%
3961048 4953.1.1.7 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › AI-2E_transport 0.62 49.0 4.97e-01 86.5% 87.8%
4295514 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.61 48.0 4.53e-01 100.0% 70.5%
3577937 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 51.0 4.61e-01 89.9% 82.6%
4457750 3567.1.1.112 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport 0.59 47.0 4.46e-01 93.3% 70.9%
3963373 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.58 50.0 3.58e-01 97.8% 58.6%
3266118 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.58 48.0 4.27e-01 87.6% 76.8%
3994851 601.1.2.63 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R 0.58 39.0 3.28e-01 91.0% 40.7%
3890271 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 49.0 3.68e-01 96.6% 82.2%
3864662 604.1.1.95 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KIAA1755_C 0.56 44.0 4.43e-01 82.0% 91.1%
3394395 1134.1.1.2 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › INT_SG_DDX_CT_C 0.56 40.0 4.27e-01 74.2% 82.5%
3829525 5050.1.1.11 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 0.56 52.0 3.80e-01 100.0% 85.0%
4327137 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.56 50.0 4.49e-01 97.8% 90.2%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.56 46.0 4.25e-01 87.6% 79.1%
4123754 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.55 49.0 4.25e-01 94.4% 86.9%
4332277 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.55 50.0 4.40e-01 97.8% 89.6%
4672121 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.55 37.0 3.40e-01 98.9% 50.8%
4486192 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.54 48.0 4.26e-01 95.5% 90.2%
4303360 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.54 48.0 4.26e-01 97.8% 87.5%
4158713 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.54 47.0 4.14e-01 94.4% 89.2%
4870707 4121.1.1.2 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like 0.54 47.0 3.43e-01 94.4% 76.7%
3610403 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 44.0 3.62e-01 87.6% 72.8%
3789380 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 33.0 3.61e-01 77.5% 74.7%
3640652 5054.1.1.12 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › NCA2 0.52 48.0 3.68e-01 100.0% 75.8%
3739861 101.1.2.198 alpha arrays › HTH › HTH › winged helix domain › ORC1_wHTH 0.52 37.0 3.40e-01 74.2% 67.8%
5030226 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.52 39.0 2.77e-01 82.0% 54.8%
3971841 3552.1.1.1 alpha arrays › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › Pfam family PF09836 N-terminal domain › DUF2063 0.51 41.0 3.64e-01 85.4% 63.2%
4323903 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.51 44.0 3.87e-01 93.3% 85.4%
3508214 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.51 41.0 3.63e-01 86.5% 81.5%
4353116 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.51 45.0 4.02e-01 97.8% 89.6%