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LR595863.1__VUD36661.1__X__00022

Bact-Vir

LR595863.1__VUD36661.1__X__00022

Identity

Accession:
LR595863 ↗
Kingdom:
phage

Quality

86.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 18-126
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13006.13 best Nterm_IS4 119.0 1.10e-34 85.3% 99.0%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7ml0M01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 41.0 4.58e-01 80.7% 100.0%
3c5iA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.55 47.0 3.64e-01 99.1% 80.3%
3s2wG00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 45.0 4.25e-01 91.7% 78.2%
1uujA00 1.20.960.30 Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › 0.53 30.0 3.45e-01 94.5% 77.6%
1k87A02 1.10.2060.10 Mainly Alpha › Orthogonal Bundle › PutA proline dehydrogenase (PRODH), domain 2 › PutA proline dehydrogenase (PRODH), domain 2 0.52 42.0 4.25e-01 88.1% 89.0%
2qg7B02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.51 44.0 3.42e-01 100.0% 84.4%
2pbiA02 1.10.1240.60 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.50 30.0 3.14e-01 96.3% 62.4%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3985422 101.1.10.49 alpha arrays › HTH › HTH › Cyclin-like › Nterm_IS4 0.98 83.0 8.92e-01 87.2% 100.0%
4008208 101.1.1.468 alpha arrays › HTH › HTH › Three-helical HTH › Nterm_IS4 0.81 61.0 6.87e-01 80.7% 100.0%
4034131 101.1.1.248 alpha arrays › HTH › HTH › Three-helical HTH › DUF772 0.65 54.0 5.53e-01 89.9% 95.2%
3639027 101.1.1.116 alpha arrays › HTH › HTH › Three-helical HTH › Abp2 0.65 46.0 4.57e-01 74.3% 96.5%
4015391 101.1.1.116 alpha arrays › HTH › HTH › Three-helical HTH › Abp2 0.65 46.0 4.56e-01 75.2% 94.1%
4125245 101.1.2.813 alpha arrays › HTH › HTH › winged helix domain › DUF772 0.64 55.0 5.51e-01 93.6% 98.2%
3692702 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.61 54.0 4.39e-01 99.1% 58.1%
3167899 4156.1.1.0 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like 0.59 41.0 4.08e-01 90.8% 67.8%
4940719 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 45.0 4.09e-01 82.6% 68.0%
5021943 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.51 39.0 3.15e-01 83.5% 69.2%
D2 medium residues 127-237
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01609.28 best DDE_Tnp_1 47.3 3.10e-12 96.4% 47.0%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 59.0 5.25e-01 92.8% 56.4%
1bcoA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.67 63.0 4.93e-01 100.0% 52.7%
7zllA01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.67 37.0 2.70e-01 93.7% 21.9%
7pikC01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.65 56.0 4.51e-01 91.9% 54.6%
6d92A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 58.0 4.47e-01 100.0% 48.4%
3obyA02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.62 43.0 4.42e-01 94.6% 73.4%
2f9wA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.62 42.0 4.02e-01 94.6% 59.5%
3dnfA02 3.40.50.11270 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 36.0 4.12e-01 99.1% 79.5%
3gocA00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.60 52.0 4.10e-01 98.2% 45.6%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 52.0 4.35e-01 95.5% 69.1%
3flhB00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.57 38.0 3.71e-01 100.0% 61.2%
3ga2A00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.57 49.0 3.88e-01 97.3% 44.9%
2w35A00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.56 46.0 3.73e-01 97.3% 45.7%
4dkwA00 3.30.420.280 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.55 43.0 3.61e-01 100.0% 47.9%
3eulB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 38.0 3.72e-01 100.0% 64.5%
6oziB00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.54 48.0 3.75e-01 98.2% 46.1%
3i8bA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 48.0 3.58e-01 100.0% 95.4%
4nspA00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.53 46.0 3.62e-01 97.3% 45.0%
4kq9A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 40.0 4.23e-01 100.0% 91.8%
2yx6D01 3.30.420.130 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Dinitrogenase iron-molybdenum cofactor biosynthesis domain 0.52 38.0 3.95e-01 93.7% 82.4%
5fmvA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 33.0 3.70e-01 87.4% 83.3%
3w1eA02 3.40.50.10610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ABC-type transport auxiliary lipoprotein component 0.52 37.0 3.21e-01 74.8% 61.0%
3ly7A01 3.40.50.11830 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 41.0 3.63e-01 85.6% 83.2%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4008205 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.97 94.0 8.98e-01 100.0% 92.0%
3958443 2484.1.1.108 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1_assoc 0.86 71.0 5.70e-01 100.0% 48.7%
3959174 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.86 71.0 6.54e-01 100.0% 70.4%
3959120 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 64.0 7.26e-01 90.1% 100.0%
3962549 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 65.0 5.79e-01 91.9% 58.0%
3958652 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.86 70.0 5.78e-01 100.0% 51.4%
3960071 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.85 70.0 5.53e-01 100.0% 45.5%
4142588 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.85 67.0 5.54e-01 100.0% 49.2%
None 0.85 70.0 4.81e-01 100.0% 28.4%
3958247 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 70.0 5.31e-01 100.0% 40.6%
3961876 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 70.0 4.73e-01 100.0% 27.1%
None 0.85 70.0 5.27e-01 100.0% 40.4%
3957639 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.85 69.0 4.96e-01 100.0% 32.8%
4594347 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.83 73.0 4.81e-01 100.0% 25.0%
4992937 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.82 75.0 5.10e-01 100.0% 30.7%
4961488 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.82 73.0 4.88e-01 100.0% 26.6%
3957539 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.82 70.0 6.66e-01 100.0% 78.4%
4212008 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.82 69.0 4.82e-01 100.0% 30.0%
5060820 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.81 73.0 4.70e-01 100.0% 23.3%
4934684 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 64.0 6.21e-01 100.0% 76.7%
5017700 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 74.0 5.16e-01 100.0% 34.3%
4961867 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 71.0 4.75e-01 100.0% 27.4%
5040335 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 70.0 5.53e-01 100.0% 49.3%
4328684 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 72.0 4.73e-01 100.0% 24.5%
4958315 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 74.0 5.26e-01 100.0% 36.3%
4968579 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 59.0 4.35e-01 100.0% 31.5%
4269616 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.80 72.0 4.66e-01 100.0% 23.5%
3942981 2484.1.1.269 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1_4 0.79 74.0 4.99e-01 100.0% 29.7%
5027997 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.79 70.0 5.14e-01 100.0% 39.8%
3949341 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.77 68.0 4.93e-01 100.0% 37.1%
215919 2484.1.1.19 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1,Tnp_DNA_bind 0.77 72.0 4.62e-01 100.0% 26.3%
4451157 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.76 70.0 5.39e-01 100.0% 47.0%
3960382 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 71.0 4.84e-01 100.0% 31.8%
4977119 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.76 71.0 5.51e-01 100.0% 51.1%
4958703 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.75 68.0 4.80e-01 100.0% 33.8%
5005291 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.75 69.0 5.32e-01 100.0% 48.6%
5078190 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.74 68.0 5.07e-01 100.0% 41.5%
4958777 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.74 67.0 4.74e-01 100.0% 33.8%
4010299 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 66.0 4.71e-01 100.0% 34.5%
3283899 2484.1.1.148 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_5 0.73 68.0 4.66e-01 100.0% 37.4%
5040708 2484.1.1.107 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS1595 0.72 56.0 4.86e-01 94.6% 55.2%
4961941 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 63.0 4.34e-01 100.0% 29.0%
5005232 2484.1.1.332 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF772 0.70 62.0 4.47e-01 100.0% 36.0%
4966168 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.70 63.0 4.44e-01 100.0% 31.9%
2887749 2484.1.1.219 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF29688 0.69 64.0 4.92e-01 99.1% 48.9%
3254993 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 64.0 4.72e-01 100.0% 43.4%
4927589 2484.1.1.101 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 0.69 64.0 5.27e-01 100.0% 59.5%
5002475 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.68 62.0 4.30e-01 100.0% 32.1%
3523358 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.67 61.0 4.68e-01 98.2% 56.2%
3590896 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 59.0 4.11e-01 95.5% 41.7%
3957251 4325.1.1.0 mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.67 57.0 5.69e-01 93.7% 91.3%
3563471 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.67 60.0 4.59e-01 98.2% 60.4%
3932544 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.66 61.0 4.77e-01 99.1% 52.4%
3933068 2484.1.1.17 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_1 0.66 61.0 4.69e-01 98.2% 54.1%
3203226 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.66 60.0 4.76e-01 99.1% 56.3%
5008723 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.64 59.0 4.95e-01 97.3% 61.7%
3753120 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.64 58.0 4.50e-01 98.2% 57.4%
4315536 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.63 44.0 4.30e-01 100.0% 66.7%
3934870 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.61 49.0 4.73e-01 84.7% 80.8%
3593432 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 51.0 4.14e-01 89.2% 56.0%
3589909 2484.1.1.144 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.60 40.0 3.98e-01 99.1% 64.2%
3710327 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.57 44.0 4.43e-01 91.0% 80.0%
3518065 220.1.1.2 beta barrels › PH domain-like › PH domain-like › PH domain-like › WH1 0.56 37.0 3.52e-01 80.2% 56.3%
4346434 2484.1.1.40 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.54 41.0 3.88e-01 98.2% 65.2%
3600816 2484.3.1.0 mixed a+b and a/b › Ribonuclease H-like › Creatinase/prolidase N-terminal domain › Creatinase/prolidase N-terminal domain 0.54 47.0 4.04e-01 97.3% 61.7%
3517035 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 38.0 4.04e-01 93.7% 87.4%
4634997 5.1.4.17 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A,MMS1_N 0.51 42.0 2.49e-01 89.2% 24.7%
4011813 5.1.4.16 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A 0.50 42.0 2.84e-01 90.1% 54.6%
D3 medium residues 238-322
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ff2A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 44.0 3.99e-01 70.6% 91.5%
3jtzA00 3.30.160.390 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain 0.64 43.0 4.52e-01 78.8% 76.6%
3ijlA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.63 44.0 4.10e-01 72.9% 91.7%
2yh6D00 3.30.530.50 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › 0.63 44.0 4.09e-01 72.9% 68.2%
2kr7A02 2.40.10.330 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.63 35.0 4.12e-01 71.8% 80.7%
3zpeA00 2.60.90.50 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › 0.61 37.0 3.15e-01 71.8% 37.7%
3mwcA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.61 43.0 3.71e-01 72.9% 77.0%
3sc7X01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.59 41.0 2.76e-01 71.8% 21.4%
1oygA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.59 47.0 3.05e-01 89.4% 79.7%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.57 40.0 3.81e-01 72.9% 71.6%
5hesA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 41.0 4.22e-01 75.3% 97.5%
1zxfA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 39.0 3.29e-01 72.9% 71.0%
4d10F01 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.57 39.0 3.15e-01 72.9% 88.8%
1x53A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 39.0 3.42e-01 71.8% 72.5%
1cukA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 32.0 3.54e-01 91.8% 72.7%
4oxwA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.55 41.0 3.82e-01 78.8% 92.5%
2ldkA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 38.0 3.05e-01 71.8% 65.7%
7bwcA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 40.0 2.76e-01 81.2% 37.2%
3cm1A00 2.30.31.20 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB 0.54 32.0 2.75e-01 70.6% 36.0%
2psoB02 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 45.0 3.55e-01 92.9% 65.2%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 35.0 3.35e-01 80.0% 58.8%
4ywzB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.53 37.0 3.09e-01 74.1% 56.8%
3qz4A00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 40.0 2.77e-01 82.4% 51.3%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.52 36.0 3.25e-01 74.1% 59.2%
2xzlA02 2.40.30.230 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.52 30.0 3.13e-01 72.9% 59.5%
6v04A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 35.0 3.13e-01 71.8% 74.8%
4p6zM01 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.50 44.0 3.93e-01 97.6% 87.6%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3704832 5.1.3.28 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 0.63 47.0 3.00e-01 80.0% 50.1%
3651019 5.1.4.101 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DUF1618 0.62 45.0 3.19e-01 77.6% 44.4%
4965259 218.1.1.5 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MenC_N 0.61 43.0 4.13e-01 74.1% 98.0%
3984933 252.2.1.5 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_3 0.61 49.0 4.87e-01 91.8% 83.3%
3358389 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.61 37.0 3.38e-01 71.8% 45.6%
3675589 5.1.4.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40,ANAPC4_WD40 0.61 48.0 3.15e-01 87.1% 24.4%
3588583 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.60 42.0 3.52e-01 71.8% 55.9%
3391610 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 50.0 4.21e-01 94.1% 78.7%
3668385 243.1.1.89 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF7074 0.60 41.0 4.11e-01 71.8% 86.7%
3942150 252.2.1.5 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_3 0.60 46.0 4.57e-01 85.9% 78.9%
5049880 331.3.1.9 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.59 41.0 3.43e-01 72.9% 73.4%
4029439 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.59 38.0 4.20e-01 75.3% 81.2%
3887495 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.59 41.0 3.74e-01 72.9% 59.1%
3461242 331.4.1.1 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1 0.58 41.0 3.75e-01 72.9% 78.2%
4927397 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.58 46.0 3.63e-01 83.5% 68.5%
4546371 220.1.1.219 beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch 0.56 44.0 3.88e-01 82.4% 90.8%
3240661 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.56 42.0 3.22e-01 83.5% 84.1%
3509038 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.55 39.0 3.70e-01 72.9% 67.0%
3663455 5.1.3.68 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF1618 0.55 41.0 2.91e-01 81.2% 35.5%
3789520 223.2.1.32 a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_2 0.55 47.0 4.01e-01 94.1% 76.3%
4929189 5084.1.1.0 beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like 0.54 39.0 3.21e-01 75.3% 93.5%
5000386 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.53 42.0 3.59e-01 88.2% 59.3%
4973804 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 34.0 3.62e-01 83.5% 74.7%
4933284 3692.1.1.1 a+b two layers › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › OCD_Mu_crystall 0.53 45.0 3.86e-01 97.6% 92.4%
4023778 206.1.1.10 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Choline_kinase 0.53 39.0 2.63e-01 81.2% 61.9%
4996269 844.1.1.0 beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain 0.52 38.0 2.90e-01 78.8% 82.7%
142888 5.1.2.8 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_43 0.52 40.0 2.77e-01 82.4% 51.3%
5009761 331.3.1.7 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › COXG 0.52 44.0 3.69e-01 92.9% 77.9%
3414704 5.1.13.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › Propeller domain of DCAF15 › DCAF15_WD40 0.52 42.0 2.96e-01 91.8% 41.4%
3913066 223.2.1.36 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_3 0.51 44.0 3.53e-01 98.8% 73.8%
3263272 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.51 36.0 3.10e-01 74.1% 55.0%
3590351 814.1.1.3 a+b two layers › Chorismate lyase › Chorismate lyase › Chorismate lyase › UTRA 0.51 38.0 3.22e-01 78.8% 52.4%
3960415 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.51 36.0 3.20e-01 72.9% 77.5%
D4 medium residues 323-415
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4g6dB02 6.10.140.1800 Special › Helix non-globular › Helix Hairpins › 0.60 38.0 4.08e-01 71.0% 74.1%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.59 47.0 3.68e-01 86.0% 89.7%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 41.0 3.65e-01 72.0% 87.2%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.58 51.0 3.85e-01 98.9% 67.8%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 40.0 3.17e-01 71.0% 89.0%
5c4yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 42.0 3.77e-01 82.8% 54.4%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 4.12e-01 78.5% 90.2%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.56 32.0 3.81e-01 93.5% 82.8%
3n98A01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.56 47.0 3.09e-01 93.5% 89.9%
1f16A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.54 41.0 3.27e-01 80.6% 65.1%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 41.0 3.85e-01 79.6% 70.5%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.54 46.0 3.57e-01 94.6% 77.4%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.53 40.0 4.26e-01 79.6% 95.1%
6z3yB01 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.52 43.0 2.90e-01 91.4% 40.5%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.52 42.0 3.87e-01 91.4% 66.1%
4hteA01 1.20.58.1730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 45.0 3.91e-01 94.6% 64.3%
7dswA01 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.52 43.0 2.86e-01 91.4% 39.3%
4yosA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 39.0 3.38e-01 97.8% 48.1%
6ldkA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 39.0 3.27e-01 82.8% 69.2%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.40e-01 79.6% 89.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.51 35.0 3.28e-01 95.7% 58.0%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3982540 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 1.00 97.0 6.86e-01 100.0% 39.6%
3661336 143.1.1.3 alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain › MLLE_2 0.69 39.0 4.24e-01 95.7% 65.8%
5082960 159.1.2.35 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › HAAS 0.69 46.0 5.03e-01 72.0% 84.0%
4413687 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.68 38.0 3.20e-01 94.6% 33.3%
3171096 5054.1.1.12 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › NCA2 0.65 43.0 3.47e-01 77.4% 36.5%
4965791 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.63 43.0 3.22e-01 71.0% 56.5%
3720763 5086.1.1.169 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › NCA2 0.62 43.0 3.54e-01 72.0% 44.7%
5047712 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.59 37.0 4.12e-01 73.1% 78.7%
3740226 5051.1.1.7 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp 0.58 45.0 2.95e-01 84.9% 64.3%
3411996 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.57 41.0 3.53e-01 78.5% 48.3%
4519879 101.1.10.13 alpha arrays › HTH › HTH › Cyclin-like › DUF3452 0.57 49.0 3.85e-01 94.6% 54.9%
3278820 191.1.1.48 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 0.55 43.0 4.00e-01 83.9% 72.5%
3430243 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.55 38.0 4.13e-01 72.0% 91.3%
3789508 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.55 33.0 3.76e-01 74.2% 80.0%
3950613 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.54 44.0 3.79e-01 86.0% 69.9%
3949864 632.1.1.37 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF6474 0.53 36.0 3.66e-01 73.1% 71.1%
3928689 109.4.1.257 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PDS5 0.52 37.0 2.51e-01 92.5% 20.0%
5070523 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.52 39.0 3.96e-01 100.0% 78.9%
4275352 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.51 40.0 4.06e-01 100.0% 85.3%
5061725 632.23.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I 0.51 38.0 4.12e-01 77.4% 92.5%
4427284 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.51 46.0 3.74e-01 100.0% 72.6%
3931427 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.51 44.0 2.91e-01 100.0% 74.7%
3917235 101.1.10.7 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.51 43.0 3.76e-01 94.6% 78.6%
3684818 4952.1.1.1 alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › Lyase_1 0.51 34.0 3.18e-01 75.3% 55.7%
3695576 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.50 45.0 2.88e-01 97.8% 24.0%