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LR596902.1__VUE37355.1__X__00019

Bact-Vir

LR596902.1__VUE37355.1__X__00019

Identity

Accession:
LR596902 ↗
Kingdom:
phage

Quality

89.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 313-417
PDB
D2 medium residues 11-72_124-174
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06152.17 best Phage_min_cap2 37.8 1.50e-09 56.6% 17.1%
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.77 50.0 5.82e-01 70.8% 94.9%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 58.0 5.90e-01 79.6% 100.0%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 59.0 5.97e-01 82.3% 98.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 57.0 5.70e-01 80.5% 100.0%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.73 56.0 5.28e-01 79.6% 93.2%
1c17M00 1.20.120.220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A 0.73 65.0 6.09e-01 100.0% 92.3%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.72 56.0 6.04e-01 81.4% 100.0%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 5.08e-01 71.7% 98.0%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.68 49.0 4.43e-01 75.2% 80.9%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.66 45.0 5.07e-01 96.5% 92.9%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.65 42.0 4.19e-01 99.1% 64.0%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.63 56.0 4.53e-01 100.0% 84.8%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.63 44.0 3.96e-01 73.5% 71.8%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 56.0 4.54e-01 100.0% 82.5%
6cnzF00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.62 55.0 4.98e-01 99.1% 98.1%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.62 45.0 4.55e-01 76.1% 74.1%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.62 55.0 4.78e-01 97.3% 98.8%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 43.0 4.37e-01 72.6% 79.5%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 51.0 5.04e-01 90.3% 84.3%
4g10A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 46.0 4.38e-01 80.5% 94.9%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.61 43.0 4.57e-01 74.3% 89.2%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 54.0 4.40e-01 100.0% 82.7%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.60 52.0 4.71e-01 96.5% 95.7%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.60 41.0 3.78e-01 70.8% 52.7%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.60 52.0 4.67e-01 96.5% 92.7%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 47.0 3.92e-01 82.3% 96.4%
1lm3B00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.60 47.0 4.90e-01 85.0% 92.5%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 46.0 3.86e-01 81.4% 76.8%
4alyB00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.59 45.0 3.78e-01 78.8% 80.2%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.59 42.0 4.00e-01 76.1% 62.1%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.59 49.0 4.71e-01 91.2% 81.2%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.58 41.0 3.50e-01 72.6% 90.2%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 41.0 3.34e-01 74.3% 70.3%
7kypB01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.57 50.0 3.77e-01 95.6% 48.0%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 48.0 4.77e-01 95.6% 89.2%
7lb8B01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.56 49.0 3.60e-01 97.3% 45.7%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 42.0 3.51e-01 77.9% 84.1%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.56 49.0 4.25e-01 100.0% 69.0%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 41.0 3.05e-01 77.0% 45.6%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 42.0 3.41e-01 80.5% 80.8%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 49.0 4.05e-01 99.1% 83.2%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 45.0 4.37e-01 91.2% 80.8%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.55 49.0 4.92e-01 100.0% 94.7%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.54 49.0 4.92e-01 99.1% 99.1%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.54 45.0 3.72e-01 92.0% 64.5%
6nsjA00 1.25.40.600 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter 0.54 45.0 3.89e-01 92.0% 93.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.54 48.0 4.72e-01 100.0% 92.0%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.54 44.0 3.65e-01 91.2% 56.2%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.54 41.0 4.11e-01 79.6% 92.9%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.53 46.0 4.08e-01 100.0% 73.3%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 39.0 3.00e-01 77.0% 81.5%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 37.0 4.12e-01 79.6% 100.0%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.52 47.0 4.43e-01 100.0% 84.7%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.52 35.0 3.95e-01 75.2% 92.9%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 36.0 3.78e-01 77.0% 79.0%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.51 45.0 4.39e-01 99.1% 89.1%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.51 39.0 3.59e-01 80.5% 93.2%
8g59R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 44.0 3.46e-01 99.1% 89.1%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.51 38.0 3.33e-01 77.0% 73.9%
4x5mA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 35.0 3.87e-01 79.6% 95.3%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.50 43.0 4.20e-01 100.0% 83.6%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.50 45.0 4.34e-01 100.0% 87.0%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.50 42.0 4.35e-01 91.2% 95.3%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4980095 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.80 58.0 6.07e-01 75.2% 97.1%
3612163 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.75 57.0 4.45e-01 80.5% 75.7%
3353757 621.1.1.1 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GBP_C 0.74 54.0 5.78e-01 81.4% 89.5%
4949996 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.74 66.0 5.05e-01 100.0% 72.1%
4001162 7022.1.1.1 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT 0.71 61.0 4.45e-01 94.7% 58.7%
None 0.71 64.0 4.50e-01 100.0% 53.1%
3648112 7023.1.1.1 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT 0.71 61.0 5.06e-01 94.7% 62.5%
3314927 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.70 59.0 5.18e-01 100.0% 61.8%
3584182 604.9.1.18 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Zip 0.70 51.0 5.75e-01 75.2% 100.0%
4069307 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.69 55.0 4.31e-01 85.8% 67.1%
4927494 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.69 48.0 3.67e-01 71.7% 43.5%
4092432 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.68 48.0 5.16e-01 82.3% 85.3%
3418144 7022.1.1.1 alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT 0.68 61.0 4.23e-01 100.0% 55.9%
4025205 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.68 56.0 5.13e-01 88.5% 88.7%
3733626 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 56.0 5.27e-01 89.4% 78.6%
3279978 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.68 61.0 5.18e-01 100.0% 72.4%
4326722 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.66 60.0 5.09e-01 97.3% 61.1%
3834468 3745.1.1.1 alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.66 59.0 4.21e-01 100.0% 80.3%
4955295 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.65 47.0 4.67e-01 75.2% 80.8%
3813982 3745.1.1.0 alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger 0.65 58.0 4.11e-01 100.0% 82.2%
4542080 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.65 60.0 4.91e-01 100.0% 73.7%
3236897 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.64 56.0 4.69e-01 99.1% 98.0%
4943425 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.64 53.0 4.39e-01 92.0% 83.8%
4034504 601.4.1.47 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › MspA_staph 0.63 51.0 5.27e-01 94.7% 95.2%
5002997 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.63 55.0 4.24e-01 98.2% 68.1%
4996466 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.63 55.0 4.21e-01 100.0% 67.9%
5022368 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.62 56.0 4.62e-01 100.0% 72.2%
5028522 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.62 56.0 4.22e-01 100.0% 54.4%
4954427 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.62 56.0 4.24e-01 100.0% 55.5%
4999397 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.61 57.0 4.64e-01 100.0% 72.5%
5040596 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.61 54.0 4.56e-01 100.0% 71.0%
3975940 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.60 45.0 4.14e-01 78.8% 89.3%
3967618 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.60 52.0 4.45e-01 97.3% 95.3%
4981593 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.60 53.0 4.32e-01 100.0% 70.5%
3965437 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.59 52.0 4.47e-01 99.1% 95.1%
3948604 604.5.1.6 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC-like 0.59 53.0 4.47e-01 100.0% 90.5%
143208 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.59 45.0 4.37e-01 79.6% 74.2%
3971332 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.59 52.0 4.63e-01 100.0% 72.7%
3573786 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 51.0 4.27e-01 97.3% 58.5%
3272619 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 47.0 4.62e-01 87.6% 90.8%
5043389 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 53.0 4.39e-01 100.0% 58.5%
3276921 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.58 49.0 4.58e-01 93.8% 84.8%
5064709 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 53.0 4.27e-01 100.0% 72.6%
5009707 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.58 45.0 4.25e-01 90.3% 68.9%
3644885 3758.1.1.31 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › DUF677 0.57 51.0 3.75e-01 98.2% 87.5%
2492086 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 46.0 4.30e-01 87.6% 76.9%
3899959 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 42.0 4.39e-01 77.0% 96.2%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.57 42.0 4.19e-01 77.0% 98.3%
3593230 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 40.0 3.76e-01 72.6% 67.9%
None 0.57 50.0 3.81e-01 98.2% 97.8%
4876876 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 50.0 4.00e-01 95.6% 69.6%
3592441 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 51.0 4.56e-01 100.0% 95.6%
5069603 601.18.1.30 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm 0.56 46.0 4.51e-01 90.3% 84.8%
3620464 5001.1.1.52 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › SID-1_RNA_chan 0.56 49.0 3.52e-01 99.1% 46.6%
4952530 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.56 44.0 4.17e-01 85.0% 81.5%
3924662 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 40.0 4.29e-01 74.3% 95.8%
3495945 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 45.0 4.50e-01 98.2% 87.0%
3764996 11.2.1.77 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › FerA 0.55 49.0 4.87e-01 99.1% 96.7%
3221474 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.55 49.0 4.00e-01 100.0% 55.3%
4622027 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.55 47.0 3.69e-01 97.3% 74.2%
4013154 601.16.1.18 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › VBS_C3G9 0.54 46.0 4.38e-01 95.6% 85.2%
4020563 601.16.1.3 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C 0.54 44.0 4.28e-01 94.7% 79.2%
3285718 601.43.1.0 alpha bundles › Four-helical up-and-down bundle › Biofilm formation modulator YmoB › Biofilm formation modulator YmoB 0.54 44.0 4.29e-01 92.9% 81.5%
4033032 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 48.0 4.47e-01 100.0% 92.1%
3475661 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 39.0 3.56e-01 75.2% 75.9%
4249009 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.53 41.0 4.02e-01 80.5% 86.7%
3488338 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 44.0 4.09e-01 94.7% 77.3%
3225374 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.51 44.0 4.32e-01 94.7% 88.3%
D3 medium residues 73-123_175-212
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.77 61.0 6.08e-01 100.0% 82.4%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 57.0 5.63e-01 100.0% 82.3%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.66 46.0 5.03e-01 98.9% 95.5%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 45.0 4.22e-01 70.8% 60.6%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.63 52.0 5.23e-01 100.0% 91.2%
3tc1B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 51.0 3.52e-01 91.0% 47.2%
2o7gA00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.60 48.0 4.92e-01 100.0% 88.6%
1b04A03 1.10.287.610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 32.0 3.74e-01 75.3% 72.6%
4gniA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.60 41.0 4.24e-01 100.0% 74.4%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.58 38.0 3.91e-01 76.4% 68.2%
2c5zA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.57 44.0 4.38e-01 100.0% 79.6%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.57 48.0 4.05e-01 100.0% 52.8%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 47.0 4.56e-01 94.4% 82.5%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.56 36.0 3.77e-01 97.8% 71.8%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 50.0 3.62e-01 100.0% 41.4%
2hkvA01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.56 50.0 4.29e-01 98.9% 92.9%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.55 45.0 3.69e-01 88.8% 50.0%
1dofA01 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.55 43.0 3.22e-01 86.5% 85.7%
7e1lB01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 48.0 3.80e-01 100.0% 67.7%
3iylB02 1.10.2050.10 Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 0.54 40.0 3.50e-01 83.1% 51.5%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.54 39.0 3.96e-01 80.9% 77.0%
1gcbA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.53 47.0 3.06e-01 96.6% 28.2%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.53 37.0 3.73e-01 80.9% 71.1%
1wy9A00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 47.0 4.38e-01 98.9% 90.1%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 39.0 3.76e-01 76.4% 67.3%
3dkaB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.52 46.0 4.06e-01 100.0% 97.0%
1b0uA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 37.0 2.69e-01 96.6% 25.6%
1lj8A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.51 46.0 3.49e-01 98.9% 92.8%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 39.0 3.50e-01 82.0% 65.4%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.51 43.0 2.86e-01 96.6% 90.4%
3ipiA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 43.0 3.16e-01 97.8% 53.0%
4jzaA03 1.20.120.1720 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.50 38.0 3.34e-01 85.4% 81.7%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3190824 166.1.1.0 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C 0.75 58.0 6.24e-01 100.0% 98.7%
4027540 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.69 62.0 5.10e-01 100.0% 63.7%
3879854 603.1.1.89 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TRAP-gamma 0.64 56.0 5.05e-01 100.0% 74.4%
3874860 611.12.1.1 alpha bundles › N-cbl like › Izumo sperm-egg fusion protein 1 N-terminal domain › Izumo sperm-egg fusion protein 1 N-terminal domain › IZUMO 0.63 57.0 4.77e-01 100.0% 61.3%
4031303 3227.1.1.1 alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC 0.63 55.0 3.59e-01 100.0% 27.6%
3442159 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 44.0 4.39e-01 75.3% 94.7%
4017306 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.60 45.0 4.68e-01 100.0% 91.3%
4420767 3227.1.1.1 alpha complex topology › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › phosphorylation-coupled saccharide transporter ChbC › PTS_EIIC 0.60 52.0 3.32e-01 100.0% 27.3%
3715110 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.60 53.0 5.16e-01 98.9% 89.0%
4387290 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.60 53.0 3.99e-01 100.0% 86.8%
3377613 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.60 46.0 4.36e-01 98.9% 68.2%
3963643 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.58 49.0 5.03e-01 98.9% 100.0%
3626108 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.58 50.0 4.56e-01 100.0% 70.8%
5000534 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.57 52.0 4.25e-01 100.0% 69.4%
3885225 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.57 52.0 4.17e-01 98.9% 61.8%
3977737 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.56 47.0 4.38e-01 94.4% 78.3%
4955452 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.55 45.0 4.01e-01 94.4% 60.7%
4309656 5069.1.3.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt 0.55 49.0 4.71e-01 100.0% 87.0%
4237660 1008.1.1.0 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.54 45.0 4.04e-01 100.0% 65.8%
3835699 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.54 48.0 4.06e-01 100.0% 76.7%
5077194 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.53 46.0 4.25e-01 100.0% 74.8%
4026165 5050.1.1.28 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.53 44.0 3.29e-01 92.1% 43.1%
3224363 3831.1.1.0 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.51 40.0 4.12e-01 89.9% 89.4%
3452617 5059.1.1.24 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › PUNUT 0.51 47.0 3.13e-01 100.0% 26.9%
4240705 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.51 40.0 4.07e-01 94.4% 87.1%
162404 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.51 39.0 3.50e-01 82.0% 65.4%
3615878 632.1.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.51 40.0 3.98e-01 97.8% 78.9%
3968650 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.50 44.0 4.21e-01 98.9% 82.9%
3305901 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.50 42.0 3.75e-01 95.5% 74.1%
3295892 3684.1.1.1 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF615 0.50 40.0 4.16e-01 87.6% 94.1%
3960460 620.1.1.0 alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases 0.50 43.0 3.74e-01 96.6% 87.9%
D4 medium residues 213-310
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06152.17 best Phage_min_cap2 34.7 1.30e-08 94.9% 18.3%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5yxkA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 3.66e-01 87.8% 66.4%
6x4tA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 37.0 3.51e-01 85.7% 63.5%
D5 medium residues 433-607
PDB
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5hn9C00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 38.0 3.10e-01 77.1% 66.8%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002955 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.72 67.0 6.08e-01 98.9% 91.7%
5011816 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.71 50.0 5.79e-01 72.0% 97.7%
3833500 7023.1.1.1 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT 0.51 35.0 3.82e-01 88.6% 86.4%