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LSDeep1_scaffold_42_prodigal-single.1__X__X__00468

Bact-Vir

LSDeep1_scaffold_42_prodigal-single.1__X__X__00468

Identity

Kingdom:
phage

Quality

73.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-101
PDB
Domain cluster: representative
CATH (75)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.87 82.0 7.68e-01 100.0% 87.6%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.84 77.0 6.36e-01 100.0% 70.5%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.84 78.0 6.08e-01 100.0% 60.2%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.84 60.0 6.06e-01 78.1% 74.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.83 76.0 7.04e-01 100.0% 95.0%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 59.0 6.53e-01 77.1% 94.7%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 58.0 6.42e-01 77.1% 92.2%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.81 71.0 6.95e-01 95.8% 96.1%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 57.0 6.02e-01 78.1% 83.5%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.79 73.0 6.51e-01 100.0% 83.2%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.79 72.0 6.77e-01 100.0% 89.6%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.79 72.0 6.84e-01 100.0% 93.8%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 58.0 5.65e-01 78.1% 96.2%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 70.0 6.12e-01 100.0% 79.7%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.77 71.0 6.83e-01 100.0% 95.3%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.77 69.0 6.32e-01 100.0% 96.9%
2okuA00 1.20.120.470 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain 0.77 55.0 5.08e-01 75.0% 68.9%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.76 68.0 5.58e-01 100.0% 70.2%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.75 68.0 6.31e-01 100.0% 87.4%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 65.0 6.08e-01 94.8% 98.3%
3vnxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 58.0 4.56e-01 82.3% 82.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.74 67.0 6.29e-01 100.0% 95.7%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.74 67.0 5.81e-01 100.0% 82.9%
6a7hA01 1.20.140.180 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.74 50.0 4.44e-01 76.0% 50.0%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 65.0 5.09e-01 100.0% 57.6%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 55.0 5.16e-01 80.2% 77.1%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 54.0 5.36e-01 79.2% 88.2%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.72 65.0 5.95e-01 100.0% 88.8%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.71 55.0 5.22e-01 82.3% 71.1%
4rflA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.71 53.0 4.19e-01 79.2% 41.2%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.71 67.0 6.01e-01 100.0% 81.7%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 53.0 5.15e-01 80.2% 85.8%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.70 63.0 5.38e-01 100.0% 86.3%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 51.0 4.09e-01 79.2% 39.2%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.70 64.0 6.04e-01 100.0% 85.2%
1aj3A00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 51.0 5.09e-01 77.1% 94.9%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 50.0 4.83e-01 78.1% 85.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 51.0 4.82e-01 80.2% 88.9%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.68 49.0 5.25e-01 78.1% 92.4%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.67 58.0 5.51e-01 99.0% 89.9%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 50.0 4.28e-01 79.2% 75.3%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 49.0 4.39e-01 78.1% 70.6%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.66 47.0 4.31e-01 75.0% 71.3%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.66 46.0 4.54e-01 75.0% 68.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 49.0 4.86e-01 80.2% 97.0%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 50.0 4.84e-01 82.3% 92.7%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 48.0 4.03e-01 79.2% 71.1%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.65 57.0 4.96e-01 99.0% 83.3%
3ihuA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.65 55.0 4.90e-01 97.9% 64.0%
3cegA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.65 47.0 3.42e-01 78.1% 28.1%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.65 46.0 4.87e-01 74.0% 96.3%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 46.0 4.40e-01 72.9% 75.2%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 47.0 4.24e-01 79.2% 72.3%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 49.0 4.71e-01 81.2% 91.7%
3ug9A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 56.0 4.29e-01 97.9% 60.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 47.0 4.76e-01 80.2% 89.8%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.64 53.0 4.03e-01 90.6% 61.3%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 46.0 4.07e-01 78.1% 55.7%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 47.0 4.21e-01 80.2% 87.9%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 54.0 4.93e-01 100.0% 97.0%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.62 44.0 4.79e-01 72.9% 93.4%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 45.0 4.73e-01 78.1% 92.0%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.60 44.0 3.87e-01 77.1% 84.9%
3g7rA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 52.0 4.21e-01 97.9% 58.2%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.59 47.0 4.26e-01 84.4% 70.5%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.58 42.0 4.11e-01 77.1% 93.3%
5c4yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 51.0 4.57e-01 97.9% 81.6%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.58 42.0 4.12e-01 79.2% 70.9%
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 51.0 3.36e-01 100.0% 39.3%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 42.0 4.03e-01 81.2% 90.1%
1i36A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.54 44.0 4.36e-01 86.5% 100.0%
2yykA01 1.10.3140.10 Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1 0.52 45.0 3.99e-01 95.8% 66.4%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 42.0 4.10e-01 90.6% 91.7%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.50 45.0 4.32e-01 100.0% 88.0%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.50 38.0 4.03e-01 96.9% 96.4%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3441289 3684.1.1.19 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 0.85 79.0 6.35e-01 100.0% 88.6%
5041256 601.4.1.91 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF30769 0.85 78.0 7.60e-01 99.0% 100.0%
4412477 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.85 78.0 7.08e-01 100.0% 88.0%
4014383 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 78.0 6.79e-01 100.0% 94.3%
4944283 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 78.0 6.77e-01 100.0% 86.4%
3786136 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.83 62.0 5.86e-01 78.1% 76.5%
3690717 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.83 76.0 6.23e-01 100.0% 82.9%
3612529 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.83 74.0 5.76e-01 100.0% 47.2%
3526861 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.82 62.0 5.90e-01 79.2% 81.8%
4988269 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.82 70.0 7.06e-01 99.0% 93.7%
5040635 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.81 75.0 7.04e-01 100.0% 90.4%
3598985 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.81 74.0 6.10e-01 100.0% 57.6%
3255556 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.81 73.0 5.12e-01 99.0% 44.8%
4987042 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.80 73.0 6.52e-01 100.0% 89.6%
4525372 601.18.1.24 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Spore_YpjB 0.80 70.0 7.22e-01 96.9% 100.0%
4018342 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.80 73.0 6.92e-01 100.0% 85.5%
4949854 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.80 73.0 6.95e-01 100.0% 87.6%
3701766 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.80 74.0 5.85e-01 100.0% 52.8%
4567957 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.79 60.0 5.60e-01 79.2% 84.3%
4927087 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.78 69.0 7.00e-01 100.0% 96.8%
2080122 601.4.1.4 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PilJ 0.78 71.0 6.83e-01 100.0% 88.1%
4974664 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.78 71.0 6.59e-01 100.0% 83.3%
3391109 3684.1.1.21 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 0.78 70.0 6.12e-01 97.9% 99.3%
4647884 601.2.1.7 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › HBM 0.77 69.0 6.19e-01 100.0% 96.3%
3488291 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 56.0 5.47e-01 77.1% 90.5%
3502048 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.75 66.0 6.68e-01 100.0% 97.9%
1518845 601.41.1.1 alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein › DUF3829_2nd 0.75 68.0 6.55e-01 100.0% 95.3%
3975382 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.75 67.0 6.01e-01 100.0% 74.1%
3275304 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.75 68.0 6.22e-01 100.0% 83.2%
3971908 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.75 67.0 6.15e-01 100.0% 79.2%
4139505 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.74 66.0 6.02e-01 100.0% 76.2%
3270445 633.21.1.22 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › COPI_assoc 0.74 55.0 5.19e-01 78.1% 78.3%
3746563 3755.3.1.123 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin 0.74 56.0 4.77e-01 79.2% 86.0%
4195415 3755.3.1.363 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T1-F 0.74 61.0 5.62e-01 100.0% 69.6%
3783862 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.73 55.0 4.00e-01 79.2% 42.7%
5012345 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.73 55.0 4.04e-01 80.2% 41.2%
5009681 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.73 66.0 5.80e-01 100.0% 97.9%
3931142 601.1.1.25 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.73 65.0 6.17e-01 100.0% 88.7%
54592 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.72 65.0 5.99e-01 100.0% 90.2%
3501178 3755.4.1.31 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Fry_C 0.72 53.0 4.18e-01 78.1% 83.9%
4989900 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.72 65.0 5.80e-01 100.0% 72.6%
3974898 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.72 64.0 5.29e-01 100.0% 62.9%
5023033 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.72 63.0 5.98e-01 99.0% 91.3%
3593997 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 62.0 5.67e-01 100.0% 82.3%
4013285 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.70 52.0 3.88e-01 78.1% 67.9%
3742744 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 52.0 4.77e-01 79.2% 83.2%
3304974 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.69 61.0 4.36e-01 96.9% 66.8%
4464029 5000.6.1.1 alpha arrays › Toxins' membrane translocation domains › Tethering factor for nuclear proteasome cut8 › Tethering factor for nuclear proteasome cut8 › Cut8 0.69 51.0 3.92e-01 78.1% 46.5%
3236399 611.3.1.1 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.68 44.0 4.74e-01 77.1% 77.5%
3808199 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 58.0 3.65e-01 91.7% 72.3%
4040220 5073.1.2.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.67 48.0 3.67e-01 75.0% 35.6%
3401257 192.15.1.92 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › TRC8_N 0.66 58.0 5.29e-01 100.0% 92.3%
4974646 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 59.0 5.77e-01 100.0% 91.4%
3568926 7515.1.1.6 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Phosphodiest 0.65 55.0 3.60e-01 100.0% 21.7%
3600444 7064.1.1.0 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.65 52.0 4.53e-01 92.7% 56.6%
3806870 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.64 44.0 4.41e-01 76.0% 68.0%
3257428 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 57.0 3.94e-01 93.8% 35.9%
3367916 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.64 50.0 4.31e-01 86.5% 52.3%
4474640 604.1.1.150 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 0.64 48.0 4.42e-01 80.2% 92.0%
3663646 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.64 51.0 4.66e-01 86.5% 65.6%
3928979 4336.2.1.0 alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 0.64 56.0 5.04e-01 100.0% 73.3%
3765900 109.4.1.470 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 0.63 47.0 4.28e-01 77.1% 60.0%
3612633 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.63 45.0 4.32e-01 75.0% 76.4%
3935426 109.4.1.791 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.63 53.0 5.37e-01 93.8% 90.5%
3497110 109.46.1.0 alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) 0.62 55.0 4.79e-01 100.0% 64.7%
3911818 3832.1.1.1 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 0.62 54.0 4.53e-01 96.9% 60.6%
5053943 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.62 49.0 4.21e-01 90.6% 54.0%
3559937 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 46.0 4.53e-01 79.2% 95.2%
3588128 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.62 46.0 3.49e-01 80.2% 42.1%
3947117 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.60 52.0 4.70e-01 97.9% 83.7%
4026288 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.59 47.0 3.58e-01 85.4% 48.9%
4176312 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.57 47.0 4.65e-01 88.5% 100.0%
5028175 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.57 48.0 3.73e-01 93.8% 65.6%
4944372 5073.1.2.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.56 49.0 3.61e-01 99.0% 35.9%
5003395 5073.1.2.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.55 47.0 3.78e-01 97.9% 46.2%
4963289 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.52 43.0 3.50e-01 91.7% 79.5%
D2 high residues 474-651
PDB
Domain cluster: representative
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.77 63.0 5.01e-01 84.3% 87.1%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.77 54.0 6.18e-01 90.4% 95.5%
3u9jA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.76 63.0 6.63e-01 97.8% 96.8%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 59.0 5.14e-01 81.5% 89.6%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 51.0 5.91e-01 89.3% 96.1%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 58.0 5.15e-01 82.0% 85.6%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 50.0 4.80e-01 87.6% 61.5%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.73 54.0 5.76e-01 97.2% 88.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 43.0 5.19e-01 74.7% 88.3%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 54.0 4.85e-01 77.5% 81.0%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 56.0 4.94e-01 80.9% 88.4%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 52.0 5.69e-01 94.9% 92.3%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.71 53.0 4.93e-01 77.0% 87.9%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 50.0 4.97e-01 82.0% 68.3%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.70 40.0 5.03e-01 77.0% 90.2%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 53.0 4.88e-01 78.7% 91.3%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 50.0 4.46e-01 72.5% 87.3%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.69 46.0 4.62e-01 92.7% 65.2%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 45.0 5.32e-01 78.1% 95.1%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 40.0 4.93e-01 73.6% 90.2%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 52.0 4.62e-01 77.5% 85.1%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 41.0 4.93e-01 71.3% 88.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.69 42.0 5.26e-01 91.0% 100.0%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.69 61.0 6.00e-01 94.9% 88.8%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.68 52.0 4.69e-01 79.2% 86.5%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 51.0 4.69e-01 78.7% 85.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 36.0 4.54e-01 74.2% 86.0%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 45.0 4.81e-01 87.6% 77.8%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 47.0 4.44e-01 71.9% 92.8%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 37.0 4.60e-01 74.7% 89.1%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 46.0 4.87e-01 88.2% 81.3%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 49.0 4.80e-01 77.0% 80.6%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 48.0 4.20e-01 75.3% 89.3%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.65 43.0 4.93e-01 72.5% 89.5%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.65 32.0 4.52e-01 70.8% 96.6%
3edvA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 38.0 3.84e-01 70.8% 55.2%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.65 49.0 5.28e-01 94.9% 92.2%
2or0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 52.0 5.14e-01 87.1% 80.6%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.63 54.0 5.32e-01 91.6% 85.9%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.63 37.0 4.37e-01 84.3% 84.2%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.63 43.0 4.30e-01 75.8% 66.3%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.63 38.0 4.73e-01 84.3% 98.2%
3mk7A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.62 53.0 3.93e-01 92.7% 95.5%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 50.0 4.36e-01 85.4% 84.6%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.61 43.0 4.49e-01 71.9% 99.4%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 37.0 4.45e-01 73.0% 93.8%
5x56B00 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.61 37.0 4.52e-01 78.1% 100.0%
3kbtA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 44.0 3.70e-01 73.6% 52.5%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 37.0 4.41e-01 71.3% 93.0%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 34.0 4.30e-01 74.7% 95.0%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 34.0 4.26e-01 71.3% 96.1%
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 51.0 4.51e-01 94.9% 82.9%
2iakA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 4.18e-01 78.7% 87.0%
6pnjL00 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.56 34.0 3.62e-01 71.3% 67.3%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 4.24e-01 78.7% 80.2%
5azpB01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.55 49.0 3.86e-01 95.5% 87.5%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 32.0 3.89e-01 80.3% 90.7%
3wmeA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.54 45.0 3.76e-01 89.9% 99.4%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 43.0 4.24e-01 92.1% 78.6%
7wivA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 3.66e-01 91.0% 99.0%
7yu4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.50 44.0 3.93e-01 94.9% 77.4%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4637398 3684.1.1.10 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 0.79 69.0 5.80e-01 92.7% 83.4%
3221996 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.76 58.0 6.24e-01 91.0% 93.3%
3801950 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.75 46.0 4.41e-01 92.7% 53.2%
3412278 4177.2.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.73 63.0 5.29e-01 92.1% 85.0%
3910599 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.73 44.0 5.41e-01 70.8% 93.0%
2320846 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.72 59.0 5.69e-01 84.8% 83.2%
3600968 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.72 47.0 5.18e-01 82.0% 81.2%
3741527 3285.1.1.1 alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain › ALIX_LYPXL_bnd 0.70 53.0 4.13e-01 77.5% 80.5%
3520964 4177.2.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.70 61.0 4.79e-01 92.1% 77.8%
3603171 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 62.0 6.24e-01 93.3% 94.9%
3458456 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 62.0 5.64e-01 94.9% 84.7%
3544537 604.1.1.63 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 0.70 44.0 5.37e-01 70.2% 97.4%
3907116 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 44.0 4.77e-01 77.0% 74.7%
3682306 633.23.1.32 alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.68 52.0 5.46e-01 81.5% 86.1%
3347110 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.68 58.0 5.22e-01 91.6% 68.3%
3574755 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.67 39.0 4.81e-01 70.8% 91.8%
3887920 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 44.0 4.72e-01 70.8% 75.5%
3877415 604.1.1.118 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.66 46.0 4.88e-01 70.8% 81.2%
4018180 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.66 47.0 4.12e-01 71.9% 71.8%
3833759 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.66 54.0 5.01e-01 93.8% 69.1%
3235327 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 39.0 3.63e-01 71.3% 47.4%
3892495 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.66 40.0 4.71e-01 73.0% 87.5%
3685679 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 54.0 5.74e-01 86.5% 98.7%
4080313 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.65 44.0 4.91e-01 76.4% 85.7%
3372974 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.65 57.0 5.01e-01 93.8% 73.8%
3437243 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.65 46.0 5.15e-01 77.0% 94.8%
3726953 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 44.0 5.03e-01 71.3% 91.1%
3591412 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.64 49.0 4.92e-01 96.1% 78.9%
3935633 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.64 45.0 4.44e-01 70.8% 68.1%
3757027 150.1.1.119 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Clusterin 0.62 47.0 4.85e-01 83.7% 83.6%
3691581 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 42.0 4.71e-01 72.5% 91.1%
3883945 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.61 42.0 4.17e-01 70.8% 65.3%
4946275 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.61 43.0 3.77e-01 72.5% 92.7%
3473587 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 37.0 4.29e-01 70.2% 85.6%
3896888 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 36.0 4.23e-01 70.2% 84.0%
4877501 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.60 50.0 5.23e-01 88.8% 98.8%
3442894 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.59 43.0 4.77e-01 78.7% 93.1%
3604134 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 41.0 4.16e-01 71.3% 86.3%
3232159 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.58 48.0 3.98e-01 87.6% 79.7%
3271160 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 41.0 3.84e-01 71.9% 100.0%
4888150 1075.4.1.9 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane 0.56 40.0 3.27e-01 72.5% 52.3%
3245682 601.1.3.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_middle 0.55 41.0 4.38e-01 93.3% 85.6%
3868371 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.55 40.0 4.03e-01 74.7% 91.1%
4947567 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 38.0 2.88e-01 70.8% 61.3%
4018104 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 40.0 3.39e-01 76.4% 63.1%
2329732 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.54 37.0 4.12e-01 93.8% 88.2%
3175425 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 37.0 3.70e-01 83.1% 66.8%
3596737 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.52 34.0 3.93e-01 77.0% 89.2%
D3 high residues 654-769
PDB
D4 medium residues 110-232
PDB
Domain cluster: representative
CATH (70)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 60.0 5.44e-01 92.7% 96.4%
8cdaB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 49.0 4.45e-01 70.7% 62.9%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.68 55.0 5.74e-01 92.7% 93.8%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.68 54.0 5.37e-01 94.3% 81.2%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.68 54.0 5.79e-01 90.2% 98.1%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.66 58.0 5.23e-01 95.9% 83.1%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.66 50.0 4.64e-01 80.5% 82.7%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.65 53.0 5.39e-01 87.8% 95.9%
4jvsA01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 51.0 5.11e-01 83.7% 92.1%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.65 53.0 5.64e-01 87.0% 100.0%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.65 55.0 4.80e-01 91.9% 76.6%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.65 55.0 4.74e-01 92.7% 72.4%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 39.0 3.89e-01 98.4% 56.9%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 51.0 5.26e-01 85.4% 100.0%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.64 55.0 4.98e-01 95.9% 83.3%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 40.0 3.68e-01 95.9% 47.8%
2jifA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 45.0 4.21e-01 73.2% 61.7%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 43.0 4.94e-01 74.0% 97.7%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 45.0 4.21e-01 74.0% 67.1%
8g59R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 54.0 4.18e-01 91.9% 86.8%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 45.0 4.23e-01 73.2% 66.9%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.63 53.0 5.32e-01 92.7% 95.2%
5hyhA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.63 45.0 3.41e-01 73.2% 64.5%
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 55.0 4.36e-01 95.9% 81.3%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 53.0 5.28e-01 92.7% 87.5%
4hyjA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 53.0 4.34e-01 92.7% 83.9%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.63 43.0 4.49e-01 70.7% 94.7%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 53.0 4.01e-01 91.9% 78.0%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 39.0 3.55e-01 72.4% 48.1%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 53.0 5.14e-01 93.5% 100.0%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 52.0 5.26e-01 91.1% 98.4%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 51.0 5.22e-01 89.4% 94.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.61 37.0 4.26e-01 95.9% 83.3%
2or0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 43.0 3.78e-01 73.2% 64.5%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 51.0 5.11e-01 93.5% 92.8%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 52.0 4.32e-01 94.3% 85.3%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 40.0 3.69e-01 91.9% 53.2%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.60 52.0 4.54e-01 94.3% 69.6%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.60 42.0 3.93e-01 73.2% 56.7%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.60 47.0 4.74e-01 83.7% 98.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 41.0 4.56e-01 74.8% 91.4%
1e3mB04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.60 51.0 4.77e-01 93.5% 88.8%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.60 48.0 5.03e-01 87.0% 94.7%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.59 42.0 4.67e-01 77.2% 93.7%
6gpxB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 50.0 3.92e-01 92.7% 84.4%
4mbsA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 50.0 3.63e-01 92.7% 83.8%
3rvyA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.58 49.0 5.09e-01 94.3% 100.0%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 34.0 3.13e-01 90.2% 42.1%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 49.0 4.22e-01 92.7% 99.5%
2cwlB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 44.0 3.37e-01 78.9% 87.4%
5lweA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 48.0 3.79e-01 91.9% 78.9%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 40.0 3.83e-01 72.4% 95.4%
4zudA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 49.0 3.89e-01 92.7% 85.9%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 49.0 4.66e-01 93.5% 96.6%
7rkxR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 48.0 3.80e-01 92.7% 82.3%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 36.0 4.12e-01 74.8% 88.5%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.57 47.0 4.53e-01 90.2% 100.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.55 43.0 4.02e-01 83.7% 76.8%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.54 46.0 4.70e-01 94.3% 99.2%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 45.0 3.51e-01 92.7% 74.7%
6gyhA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 45.0 3.73e-01 92.7% 56.0%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.53 39.0 3.87e-01 76.4% 98.4%
2nwbA02 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 45.0 3.65e-01 94.3% 79.7%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.53 33.0 2.79e-01 95.9% 35.7%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.52 42.0 4.00e-01 87.0% 86.9%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 37.0 2.88e-01 74.0% 62.2%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.51 42.0 4.12e-01 87.8% 84.7%
1q8dA00 1.10.220.110 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › GDNF binding domain 0.50 37.0 3.97e-01 75.6% 95.0%
7w5lA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.50 38.0 3.08e-01 79.7% 75.6%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 43.0 3.38e-01 90.2% 91.4%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018475 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 60.0 6.06e-01 92.7% 86.7%
4181721 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 60.0 6.04e-01 93.5% 98.4%
5005799 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.68 58.0 4.88e-01 92.7% 61.4%
3711619 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.67 58.0 5.46e-01 95.1% 84.0%
3496501 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.67 49.0 4.05e-01 74.8% 52.4%
3471983 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.66 47.0 4.53e-01 73.2% 77.9%
3226256 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.66 57.0 5.26e-01 92.7% 85.8%
4845657 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.66 45.0 3.97e-01 78.0% 47.5%
3958107 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.66 46.0 4.19e-01 70.7% 56.9%
3969575 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.66 53.0 5.22e-01 94.3% 79.3%
3498285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 59.0 5.63e-01 96.7% 92.1%
3220259 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 57.0 4.14e-01 94.3% 77.5%
5006341 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.65 53.0 5.27e-01 87.8% 96.1%
5082667 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.65 45.0 4.37e-01 72.4% 64.4%
3278762 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.64 46.0 4.20e-01 73.2% 60.4%
3725025 5001.1.1.125 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF7703 0.64 56.0 4.28e-01 94.3% 75.6%
3308733 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.63 53.0 4.39e-01 92.7% 54.3%
5031425 601.7.1.3 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 0.63 56.0 5.56e-01 95.9% 91.5%
4311111 192.29.1.160 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › YPEB_N 0.63 55.0 5.00e-01 96.7% 79.4%
4926950 3281.1.1.1 alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M 0.63 55.0 3.49e-01 96.7% 25.3%
5083949 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.63 39.0 3.85e-01 97.6% 58.5%
3765 601.26.1.1 alpha bundles › Four-helical up-and-down bundle › YppE-like › YppE-like › DUF1798 0.62 52.0 5.31e-01 91.9% 97.5%
3253939 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 52.0 5.32e-01 91.9% 96.7%
5069603 601.18.1.30 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm 0.62 53.0 5.32e-01 92.7% 95.2%
3490970 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 53.0 5.31e-01 93.5% 92.8%
3239393 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 50.0 5.22e-01 90.2% 97.3%
3246131 192.29.1.93 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › WSN 0.61 51.0 4.87e-01 91.9% 91.7%
3410882 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.61 53.0 3.80e-01 94.3% 74.3%
3813600 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 42.0 4.08e-01 75.6% 63.7%
4117026 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.61 51.0 4.19e-01 91.9% 63.0%
3377749 3843.1.1.15 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › ETR1_N 0.60 40.0 4.39e-01 72.4% 84.0%
3343869 5001.1.1.122 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 0.60 50.0 3.78e-01 91.9% 75.8%
3735775 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 42.0 3.40e-01 72.4% 38.7%
3804987 5001.1.1.122 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF27754 0.59 50.0 3.74e-01 92.7% 75.3%
4884076 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.59 44.0 4.45e-01 77.2% 82.5%
4342803 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 41.0 4.29e-01 75.6% 79.1%
3973285 3755.1.1.28 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › PF25876 0.59 37.0 3.60e-01 97.6% 56.3%
4363131 604.5.1.32 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TMEM120A-B 0.58 52.0 4.37e-01 98.4% 65.2%
3614951 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 50.0 4.68e-01 95.9% 79.4%
4527941 101.1.4.3 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 0.58 50.0 4.87e-01 95.9% 95.0%
3802836 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 41.0 3.65e-01 72.4% 73.1%
4952530 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.58 49.0 4.77e-01 93.5% 99.3%
3917447 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 38.0 3.71e-01 74.8% 59.3%
4327369 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.58 48.0 3.99e-01 92.7% 76.1%
3807085 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.57 38.0 4.36e-01 75.6% 97.6%
3266546 5001.1.1.79 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › YhhN 0.57 48.0 3.76e-01 92.7% 98.9%
3215760 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 47.0 3.70e-01 92.7% 78.2%
4001372 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.57 48.0 3.59e-01 93.5% 39.4%
3978522 1014.1.1.1 alpha arrays › AopB › AopB › AopB › SseC 0.56 42.0 3.64e-01 78.0% 55.8%
3690080 603.5.1.0 alpha bundles › STAT-like › FlgN-like › FlgN-like 0.56 47.0 4.76e-01 89.4% 100.0%
3289769 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.55 43.0 4.64e-01 89.4% 100.0%
3542203 3755.3.1.44 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › JMY 0.55 43.0 3.65e-01 82.1% 84.0%
3948903 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 48.0 4.07e-01 94.3% 92.5%
3194706 3755.4.1.5 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Dynactin 0.55 49.0 3.50e-01 100.0% 61.6%
3279694 5050.1.1.60 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 0.54 47.0 4.10e-01 97.6% 68.4%
4501248 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.54 47.0 4.20e-01 94.3% 97.6%
3408992 109.4.1.403 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1 0.54 38.0 3.37e-01 72.4% 53.3%
5047252 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.54 45.0 3.41e-01 89.4% 74.3%
3636705 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.54 41.0 3.09e-01 80.5% 72.1%
3386489 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.53 40.0 3.66e-01 80.5% 88.2%
3280967 5050.1.1.60 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 0.53 46.0 4.01e-01 96.7% 67.7%
3916044 3684.1.1.35 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › JMY 0.53 45.0 4.15e-01 92.7% 93.8%
3252200 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.52 40.0 3.70e-01 81.3% 76.2%
4024773 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.52 43.0 3.94e-01 93.5% 79.4%
3623906 603.1.1.103 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 0.51 44.0 4.34e-01 93.5% 91.9%
3623280 603.1.1.110 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.51 43.0 3.74e-01 92.7% 88.7%
3716333 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.50 43.0 3.57e-01 93.5% 91.2%
D5 medium residues 233-336
PDB
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1eb6A00 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.78 66.0 5.49e-01 91.3% 91.0%
1h19A02 3.30.2010.30 Alpha Beta › 2-Layer Sandwich › Zincin-like › 0.74 63.0 6.57e-01 97.1% 99.0%
4jiuA00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.73 51.0 5.15e-01 74.0% 71.4%
4wz9A02 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.73 65.0 4.84e-01 98.1% 82.3%
4jixB00 3.30.2010.10 Alpha Beta › 2-Layer Sandwich › Zincin-like › "Metalloproteases (""zincins""), catalytic domain" 0.71 52.0 5.21e-01 76.9% 75.0%
4ar9A01 3.40.30.160 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Collagenase ColT, N-terminal domain 0.71 63.0 5.74e-01 99.0% 89.4%
4l7aA00 3.40.390.70 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › 0.68 61.0 4.59e-01 100.0% 51.7%
4fcaA02 3.40.390.80 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Peptidase M60, enhancin-like domain 2 0.65 54.0 5.01e-01 92.3% 100.0%
3l3bA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.64 54.0 4.28e-01 91.3% 99.0%
3c4nA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.59 49.0 3.81e-01 91.3% 97.4%
4okoA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.59 52.0 3.83e-01 100.0% 82.1%
4paaA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 48.0 3.67e-01 90.4% 80.8%
6q3wD01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.57 42.0 3.44e-01 88.5% 42.8%
4yshA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 47.0 3.65e-01 90.4% 90.6%
2k6vA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 47.0 3.99e-01 91.3% 87.2%
3kkiA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.56 44.0 3.92e-01 86.5% 72.7%
1rsgA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 46.0 3.54e-01 92.3% 96.3%
3drnB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 47.0 4.18e-01 98.1% 92.0%
3iwaA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 43.0 3.81e-01 90.4% 94.3%
3gzaA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 43.0 3.10e-01 92.3% 95.9%
1h70A00 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.52 42.0 3.16e-01 87.5% 96.9%
1fjmB00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.51 40.0 2.99e-01 86.5% 56.4%
5epfA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 44.0 3.92e-01 98.1% 92.2%
6juyC01 3.75.10.10 Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A 0.51 40.0 3.01e-01 84.6% 98.5%
3icfB00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.50 40.0 2.92e-01 87.5% 54.8%
5yjwA00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.50 45.0 2.95e-01 100.0% 79.3%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3969078 2498.1.1.156 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › DUF7844 0.79 70.0 5.45e-01 93.3% 62.4%
5011816 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.77 55.0 5.08e-01 73.1% 64.6%
5028287 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.75 65.0 5.12e-01 100.0% 47.5%
4547149 2498.1.1.22 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YbeY 0.75 63.0 5.62e-01 90.4% 82.8%
5058128 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.74 63.0 5.15e-01 92.3% 89.5%
None 0.73 65.0 6.16e-01 94.2% 84.2%
3797507 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.73 66.0 4.84e-01 99.0% 80.4%
3616679 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.73 66.0 4.83e-01 99.0% 80.4%
3574082 2498.1.1.39 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SprT-like 0.72 52.0 5.57e-01 75.0% 87.8%
3686613 261.1.1.0 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain 0.71 62.0 5.50e-01 96.2% 94.7%
3216540 2498.1.1.69 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › PIG-S 0.71 60.0 5.24e-01 92.3% 81.3%
3200271 2007.2.2.8 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Phosphotyrosine protein phosphatases I-like › PIG-S 0.70 59.0 5.10e-01 92.3% 78.2%
3957469 2498.1.1.17 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › YgjP-like 0.69 56.0 4.92e-01 85.6% 59.3%
3720589 2498.1.1.36 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › WLM 0.69 58.0 5.38e-01 93.3% 77.8%
4666609 2498.1.1.12 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M4,Peptidase_M4_C 0.69 62.0 4.44e-01 100.0% 77.0%
3596937 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.69 50.0 5.13e-01 76.0% 82.0%
4020944 2498.1.1.12 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M4,Peptidase_M4_C 0.69 59.0 3.97e-01 93.3% 32.9%
5082786 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.68 61.0 4.24e-01 100.0% 71.7%
3962296 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.65 42.0 3.24e-01 74.0% 29.6%
3708348 261.1.1.1 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.64 53.0 4.81e-01 87.5% 67.4%
3902138 261.1.1.1 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.63 53.0 3.60e-01 92.3% 27.0%
3928048 261.1.1.1 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.63 51.0 3.40e-01 88.5% 24.2%
3209417 261.1.1.1 a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.59 51.0 3.37e-01 96.2% 24.5%
3169730 109.4.1.339 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRAPPC-Trs85 0.58 49.0 3.77e-01 93.3% 90.2%
5065004 2004.11.1.0 a/b three-layered sandwiches › P-loop domains-like › PEP carboxykinase N-terminal domain › PEP carboxykinase N-terminal domain 0.58 52.0 4.15e-01 100.0% 85.2%
5073530 2004.11.1.1 a/b three-layered sandwiches › P-loop domains-like › PEP carboxykinase N-terminal domain › PEP carboxykinase N-terminal domain › PEPCK_ATP 0.57 52.0 4.21e-01 100.0% 93.3%
4366304 2004.1.2.3 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › PEP carboxykinase catalytic C-terminal domain › Hpr_kinase_C 0.57 50.0 4.40e-01 98.1% 97.4%
3554204 109.4.1.2271 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med16_C 0.56 21.0 2.98e-01 90.4% 70.0%
3594638 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.54 45.0 3.55e-01 92.3% 89.3%
4006806 2008.1.1.51 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › McrBC 0.54 47.0 3.97e-01 96.2% 89.0%
3972296 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.52 42.0 3.04e-01 90.4% 92.3%
1192643 3016.1.1.3 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_5 0.51 40.0 3.98e-01 82.7% 100.0%
290550 2002.1.1.16 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase 0.51 42.0 3.05e-01 91.3% 92.5%
5045039 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.51 42.0 3.38e-01 88.5% 99.0%
1716086 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.51 44.0 3.92e-01 98.1% 92.8%
5050199 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 34.0 2.94e-01 83.7% 44.9%
5021064 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.50 43.0 3.83e-01 98.1% 90.0%
3259570 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.50 41.0 2.95e-01 92.3% 60.9%
4173776 2002.1.1.9 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › OMPdecase 0.50 42.0 3.34e-01 91.3% 99.1%
3725605 2485.1.1.4 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › AhpC-TSA 0.50 43.0 3.76e-01 98.1% 86.1%
D6 medium residues 772-839
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4zohA05 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.55 47.0 3.79e-01 100.0% 91.1%
2e1qC10 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.54 47.0 3.86e-01 100.0% 90.6%
1reqB01 3.20.20.240 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Methylmalonyl-CoA mutase 0.54 44.0 2.78e-01 97.1% 70.0%
4akfA01 3.40.1090.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain 0.53 43.0 2.85e-01 95.6% 27.9%
7px0A01 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.53 46.0 3.90e-01 100.0% 97.5%
1pjrA02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.51 36.0 3.64e-01 82.4% 73.6%
3hrdB02 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.50 43.0 3.44e-01 100.0% 91.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1875315 231.1.1.2 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Molybdenum cofactor-binding domain › MoCoBD_2 0.53 46.0 2.94e-01 100.0% 32.1%
3736871 108.1.1.121 alpha arrays › EF-hand › EF-hand-related › EF-hand › PF30624 0.52 43.0 3.85e-01 94.1% 97.0%
4310097 108.1.1.28 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_6,EF-hand_7 0.52 43.0 3.81e-01 91.2% 82.0%
3742551 108.1.1.121 alpha arrays › EF-hand › EF-hand-related › EF-hand › PF30624 0.52 42.0 3.88e-01 95.6% 97.9%
3746167 108.1.1.99 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5, EF-hand_6, EF-hand_7 0.50 39.0 3.58e-01 85.3% 91.1%
D7 medium residues 969-980_1149-1231
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.75 56.0 5.06e-01 80.0% 77.9%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 43.0 3.66e-01 83.2% 86.7%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 46.0 3.49e-01 95.8% 76.3%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 46.0 3.32e-01 96.8% 37.4%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.51 38.0 3.73e-01 88.4% 70.8%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4289707 192.15.1.73 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › GrpE 0.62 39.0 3.91e-01 75.8% 61.0%
4976290 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.56 40.0 4.38e-01 97.9% 88.7%
5078584 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.52 39.0 3.88e-01 93.7% 77.0%
3653649 178.1.1.1 alpha arrays › SWIB/MDM2 domain › SWIB/MDM2 domain › SWIB/MDM2 domain › SWIB 0.51 35.0 3.65e-01 74.7% 78.8%
D8 medium residues 981-1089_1118-1131
PDB
D9 medium residues 1345-1446
PDB
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l0mA02 1.20.1280.280 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 43.0 4.72e-01 89.2% 96.2%
2optA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 44.0 4.00e-01 89.2% 56.2%
3bqkA02 1.20.1310.20 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain 0.60 48.0 4.22e-01 88.2% 77.4%
7w5gA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 47.0 3.29e-01 90.2% 28.7%
4cc9B00 1.20.5.4730 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.57 33.0 3.40e-01 95.1% 58.2%
1m2oA04 1.20.120.730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain 0.57 50.0 4.61e-01 100.0% 92.0%
3k7dA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.55 49.0 3.74e-01 100.0% 66.0%
3b0pA02 1.20.120.1460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 33.0 3.73e-01 87.3% 80.0%
2n1fA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 31.0 3.28e-01 95.1% 61.8%
5lnxF01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 45.0 4.32e-01 95.1% 78.0%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.55 41.0 3.90e-01 78.4% 100.0%
3rrwB01 1.10.520.10 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › 0.54 47.0 3.94e-01 96.1% 94.0%
3rwlA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.54 47.0 3.18e-01 99.0% 72.0%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.53 37.0 3.70e-01 71.6% 88.2%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.76e-01 91.2% 65.8%
4uniC01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 46.0 3.10e-01 100.0% 51.5%
4iduB01 1.20.142.20 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › 0.51 43.0 4.07e-01 96.1% 94.5%
2xheA03 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.51 36.0 3.42e-01 72.5% 94.2%
2or0B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 40.0 3.82e-01 100.0% 71.0%
1cpcA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.51 40.0 3.58e-01 99.0% 56.8%
5cqgA03 1.10.10.2210 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.50 35.0 3.81e-01 89.2% 92.4%
5jfqB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 44.0 3.20e-01 100.0% 69.9%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2168246 1176.1.1.1 alpha arrays › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › AnfG_VnfG 0.62 48.0 4.73e-01 84.3% 89.4%
3570625 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.60 44.0 4.66e-01 88.2% 86.7%
3703752 533.1.1.1 alpha bundles › Arp2/3 complex 21 kDa subunit ARPC3 › Arp2/3 complex 21 kDa subunit ARPC3 › Arp2/3 complex 21 kDa subunit ARPC3 › P21-Arc 0.57 47.0 3.85e-01 87.3% 80.6%
3889291 5050.1.1.6 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP 0.56 44.0 3.33e-01 85.3% 65.5%
3747750 226.1.1.1 a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.55 39.0 3.11e-01 88.2% 36.4%
3623545 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 45.0 3.44e-01 88.2% 65.1%
3634549 108.1.1.20 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_like 0.54 34.0 3.61e-01 81.4% 71.1%
4886833 601.48.1.1 alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain › ArnB_C 0.54 33.0 3.41e-01 89.2% 63.9%
4978090 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.53 42.0 3.33e-01 86.3% 81.9%
5041648 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 45.0 3.72e-01 96.1% 73.2%
4527446 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 41.0 3.34e-01 85.3% 74.5%
3172240 601.2.1.5 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr 0.51 41.0 3.42e-01 91.2% 94.9%
3592870 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 38.0 3.89e-01 100.0% 83.0%
3294636 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.50 42.0 4.09e-01 94.1% 100.0%
D10 medium residues 1533-1601
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.65 34.0 3.14e-01 97.1% 37.4%
1v8bA01 3.40.50.1480 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Adenosylhomocysteinase-like 0.61 42.0 2.77e-01 72.5% 17.5%
3oa5B02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.61 47.0 2.88e-01 84.1% 14.7%
2nq2A00 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.57 48.0 3.21e-01 98.6% 60.1%
1o82A00 1.20.225.10 Mainly Alpha › Up-down Bundle › Bacteriocin As-48; Chain A › Bacteriocin AS-48 0.55 39.0 3.95e-01 78.3% 98.6%
3q9oA02 3.90.1350.10 Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain 0.55 40.0 3.13e-01 100.0% 33.5%
2dt5B01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.85e-01 76.8% 89.0%
1j78A05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.53 33.0 3.45e-01 97.1% 70.0%
5zzjA02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 47.0 3.03e-01 100.0% 23.4%
8bs9A01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.51 37.0 2.56e-01 81.2% 56.3%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3250170 3614.1.1.0 alpha arrays › T4 RNA ligase › T4 RNA ligase › T4 RNA ligase (Rnl1) C-terminal domain 0.69 58.0 4.76e-01 100.0% 53.6%
3280459 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 47.0 3.26e-01 78.3% 77.7%
4034566 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.63 54.0 3.60e-01 100.0% 78.4%
5079588 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.61 39.0 3.62e-01 100.0% 50.0%
3505729 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 38.0 3.31e-01 97.1% 46.0%
3941722 5059.1.1.18 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UPF0060 0.57 44.0 3.82e-01 84.1% 93.6%
4397604 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.55 46.0 3.90e-01 100.0% 96.9%
4938085 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.55 36.0 3.31e-01 98.6% 49.5%
4293828 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.54 45.0 3.80e-01 95.7% 97.6%
4960606 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 45.0 3.30e-01 97.1% 67.3%
5040873 4271.1.1.3 alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.52 45.0 3.23e-01 100.0% 45.6%
3270951 3092.1.1.1 alpha arrays › yeast protein YOR252W › yeast protein YOR252W › yeast protein YOR252W › Tma16 0.51 38.0 3.23e-01 82.6% 76.0%