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LT986460.2__SPF82137.1__X__00059

Bact-Vir

LT986460.2__SPF82137.1__X__00059

Identity

Accession:
LT986460 ↗
Kingdom:
phage

Quality

74.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 56-131
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.77 68.0 5.95e-01 94.7% 91.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 66.0 5.69e-01 100.0% 94.0%
1w53A00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.72 50.0 4.92e-01 84.2% 66.7%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.71 62.0 5.12e-01 98.7% 62.4%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.70 62.0 5.19e-01 100.0% 90.2%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.70 61.0 5.60e-01 97.4% 81.2%
3kd3A02 1.10.150.210 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 0.70 43.0 4.79e-01 75.0% 76.7%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 56.0 4.17e-01 88.2% 47.9%
1ui6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 62.0 4.61e-01 100.0% 45.3%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 60.0 5.39e-01 100.0% 89.6%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 60.0 4.56e-01 98.7% 53.4%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.66 58.0 4.77e-01 100.0% 57.0%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.65 58.0 4.87e-01 100.0% 66.7%
3hugA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 44.0 4.40e-01 71.1% 85.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 57.0 5.22e-01 100.0% 92.2%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.64 44.0 3.93e-01 71.1% 72.0%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 56.0 4.90e-01 100.0% 83.8%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 43.0 4.61e-01 73.7% 82.8%
3on2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 55.0 4.19e-01 100.0% 45.8%
1d8cA03 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.63 51.0 4.27e-01 89.5% 63.0%
2genA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 56.0 4.19e-01 100.0% 48.4%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 56.0 4.16e-01 100.0% 62.2%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 4.71e-01 96.1% 99.1%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 54.0 4.63e-01 100.0% 68.0%
2jaeA03 1.20.1440.240 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.62 41.0 3.78e-01 84.2% 51.5%
2yk0A03 1.20.58.1930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 3.86e-01 100.0% 51.5%
4ipeB02 3.30.230.80 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.61 46.0 3.63e-01 97.4% 37.6%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.61 54.0 4.54e-01 98.7% 89.8%
5gj7A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.61 50.0 4.34e-01 94.7% 64.8%
3m9vA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.60 50.0 4.30e-01 93.4% 63.0%
3q18A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 51.0 4.51e-01 98.7% 73.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 47.0 4.10e-01 85.5% 75.4%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 52.0 4.72e-01 100.0% 92.5%
1z6oM00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 52.0 3.95e-01 100.0% 78.0%
8cdaC01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 47.0 4.20e-01 90.8% 70.9%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 44.0 3.51e-01 80.3% 56.7%
3jcuZ00 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.59 39.0 4.16e-01 73.7% 83.6%
3nb2A02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.58 48.0 3.86e-01 94.7% 45.2%
2pusA04 6.10.140.300 Special › Helix non-globular › Helix Hairpins › 0.58 49.0 4.43e-01 96.1% 76.9%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 37.0 3.19e-01 72.4% 41.0%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.56 50.0 3.97e-01 100.0% 76.3%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 44.0 4.39e-01 90.8% 97.4%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.54 42.0 3.94e-01 84.2% 94.8%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.53 46.0 4.10e-01 100.0% 71.4%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 45.0 4.08e-01 100.0% 81.8%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3918275 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.82 73.0 5.75e-01 94.7% 53.1%
4953311 604.20.1.0 alpha bundles › Spectrin repeat-like › C-terminal domain in hypothetical protein BACOVA_03992 › C-terminal domain in hypothetical protein BACOVA_03992 0.81 63.0 5.68e-01 94.7% 62.0%
4018207 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.80 72.0 5.49e-01 97.4% 78.2%
4029241 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 60.0 4.93e-01 89.5% 49.3%
3838401 192.10.1.0 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain 0.74 61.0 5.47e-01 86.8% 70.0%
3787094 601.1.1.142 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Peptidase_S64, PF30502 0.73 68.0 5.00e-01 100.0% 47.8%
4612523 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.73 66.0 4.91e-01 100.0% 49.2%
5043155 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.72 61.0 5.15e-01 92.1% 82.4%
3809136 4133.1.1.0 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like 0.72 55.0 5.89e-01 97.4% 96.9%
1503841 109.4.1.17 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin 0.71 62.0 5.12e-01 98.7% 62.4%
4975820 4133.1.1.0 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like 0.71 52.0 5.61e-01 92.1% 98.3%
5060063 4133.1.1.0 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like 0.71 56.0 5.84e-01 98.7% 94.3%
5078867 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 62.0 5.90e-01 98.7% 97.8%
4013499 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 62.0 4.88e-01 100.0% 46.9%
3610895 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 58.0 3.98e-01 94.7% 27.2%
3628755 109.4.1.1493 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C, ZW10_C2 0.69 61.0 3.52e-01 100.0% 20.5%
3654456 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.68 59.0 3.95e-01 98.7% 75.1%
3804036 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 57.0 5.02e-01 96.1% 96.5%
3167157 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 54.0 4.31e-01 100.0% 43.2%
3255571 109.4.1.27 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › W2 0.67 59.0 4.40e-01 94.7% 50.0%
3909017 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.67 46.0 4.36e-01 71.1% 83.3%
3940779 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 58.0 5.26e-01 100.0% 97.1%
5045248 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.66 55.0 5.38e-01 93.4% 90.6%
5014336 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 53.0 4.36e-01 92.1% 78.6%
4175087 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.63 44.0 3.90e-01 73.7% 60.9%
3713159 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 55.0 4.80e-01 100.0% 85.8%
3704359 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 55.0 4.25e-01 100.0% 58.9%
3823532 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.62 53.0 4.29e-01 93.4% 70.3%
3267624 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.62 50.0 4.20e-01 90.8% 83.7%
5000174 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.61 51.0 4.67e-01 92.1% 89.0%
3620358 192.29.1.50 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA 0.61 53.0 3.87e-01 98.7% 68.2%
3242500 601.3.1.4 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PTPLA 0.61 54.0 3.92e-01 98.7% 70.5%
3720075 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 3.60e-01 98.7% 49.6%
3531347 109.4.1.498 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4487 0.60 53.0 3.86e-01 100.0% 37.2%
3356672 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.60 48.0 4.17e-01 90.8% 84.8%
3609374 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 49.0 4.44e-01 100.0% 88.2%
3726846 3924.1.1.0 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 0.54 45.0 3.41e-01 96.1% 37.1%
3982634 192.29.1.155 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF1722 0.50 38.0 3.83e-01 85.5% 88.7%
D2 medium residues 175-191_216-360
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7akwA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 48.0 4.33e-01 74.7% 57.2%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.65 49.0 5.03e-01 78.4% 89.7%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.65 45.0 5.16e-01 72.8% 100.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.65 42.0 4.90e-01 77.8% 94.5%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.65 49.0 4.69e-01 78.4% 73.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.64 45.0 5.10e-01 72.8% 94.4%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.64 46.0 4.56e-01 74.7% 71.8%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.63 46.0 3.76e-01 75.9% 90.1%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 44.0 4.81e-01 71.0% 100.0%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.62 47.0 4.75e-01 77.8% 80.4%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.62 29.0 4.04e-01 72.8% 92.1%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 35.0 4.41e-01 71.0% 94.7%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.61 47.0 4.74e-01 80.9% 86.1%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.60 43.0 4.70e-01 75.9% 91.0%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.59 48.0 5.06e-01 87.0% 100.0%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.59 43.0 4.24e-01 76.5% 78.7%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.58 28.0 3.74e-01 76.5% 84.7%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 46.0 4.35e-01 82.7% 89.6%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 32.0 3.49e-01 87.0% 62.3%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 53.0 4.41e-01 100.0% 94.9%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 47.0 3.94e-01 87.0% 97.8%
3q2qA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 52.0 4.20e-01 100.0% 93.0%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 43.0 4.05e-01 77.2% 71.1%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.57 38.0 3.53e-01 77.2% 54.5%
3anpB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 41.0 3.85e-01 75.3% 68.6%
3on2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 40.0 3.78e-01 72.8% 65.3%
1n81A00 1.10.3030.10 Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 0.55 43.0 4.12e-01 81.5% 75.8%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 37.0 3.85e-01 71.0% 81.4%
8h6qD01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 46.0 3.81e-01 100.0% 89.3%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.51 39.0 2.91e-01 79.6% 55.5%
2btdA00 1.25.40.340 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain 0.50 37.0 3.43e-01 77.8% 58.4%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4013887 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.73 50.0 5.40e-01 70.4% 96.4%
3286802 601.4.1.58 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF27150 0.72 52.0 5.52e-01 74.1% 95.0%
3939917 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 53.0 5.15e-01 77.8% 97.1%
3952394 601.4.1.58 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF27150 0.69 51.0 5.31e-01 76.5% 84.0%
3291574 192.29.1.248 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF27150 0.68 50.0 5.63e-01 75.9% 98.4%
1546262 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.68 49.0 4.68e-01 73.5% 89.9%
5073872 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.68 55.0 5.01e-01 85.8% 73.5%
3879834 3684.1.1.54 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › RHG29_45_N 0.66 45.0 5.12e-01 85.2% 93.3%
5082279 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 46.0 5.25e-01 87.7% 96.7%
4996913 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.65 51.0 4.73e-01 82.1% 75.6%
3967393 601.4.1.3 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 0.64 48.0 4.47e-01 77.2% 71.0%
3979467 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.62 53.0 4.75e-01 92.0% 97.8%
4628636 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.60 54.0 4.60e-01 96.9% 72.7%
3456677 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.60 49.0 4.09e-01 87.0% 54.4%
3263401 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.58 49.0 4.06e-01 88.9% 54.3%
5007774 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.58 42.0 3.86e-01 73.5% 67.6%
3399134 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.58 48.0 4.19e-01 88.9% 60.0%
3419853 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.58 41.0 4.34e-01 72.8% 90.3%
3276259 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.58 47.0 4.03e-01 87.0% 56.6%
4034129 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.58 51.0 4.36e-01 97.5% 60.7%
5001382 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.58 51.0 4.36e-01 96.3% 67.3%
3388915 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.57 48.0 4.01e-01 89.5% 53.8%
4430935 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.57 49.0 4.21e-01 95.7% 59.6%
3704092 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.57 43.0 3.75e-01 77.2% 62.6%
3368155 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 47.0 4.00e-01 88.9% 57.4%
4020933 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 50.0 4.16e-01 97.5% 56.9%
3823532 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.56 40.0 4.22e-01 72.8% 90.3%
3743803 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.56 48.0 4.11e-01 92.0% 63.5%
4986380 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.56 41.0 3.88e-01 75.9% 70.5%
4950954 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.56 41.0 3.89e-01 75.9% 67.0%
3929476 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 50.0 4.16e-01 98.1% 57.9%
4182407 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.56 50.0 3.44e-01 100.0% 55.5%
3682998 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 48.0 4.04e-01 95.7% 62.1%
3630952 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.56 49.0 4.07e-01 98.1% 55.7%
3257480 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 50.0 3.46e-01 100.0% 57.8%
5051018 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.56 45.0 3.72e-01 87.0% 57.0%
4412648 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.56 48.0 3.97e-01 95.7% 54.1%
3599080 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.55 49.0 4.21e-01 98.1% 61.6%
3177674 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.55 50.0 4.09e-01 98.1% 55.6%
3270443 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.55 49.0 4.19e-01 97.5% 62.6%
3185619 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.55 49.0 4.04e-01 97.5% 55.6%
3669169 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.55 44.0 3.48e-01 83.3% 98.2%
3686436 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.55 49.0 3.84e-01 98.1% 46.9%
3258643 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.55 49.0 4.14e-01 98.1% 60.0%
3270779 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.55 48.0 4.17e-01 97.5% 63.1%
3590115 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.55 48.0 4.14e-01 96.3% 72.7%
4114742 1075.1.1.20 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane+PDR_CDR 0.55 49.0 4.21e-01 98.1% 64.3%
3253732 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.54 47.0 4.07e-01 95.7% 64.2%
3394944 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.54 48.0 4.07e-01 98.1% 60.0%
3824236 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.54 48.0 4.09e-01 98.1% 60.1%
3648543 6155.1.1.16 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PF28566 0.54 46.0 4.42e-01 95.1% 79.5%
5019967 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.54 40.0 3.85e-01 77.8% 75.3%
3688451 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.53 41.0 4.35e-01 85.2% 94.9%
3252330 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.53 47.0 3.87e-01 97.5% 56.3%
4470771 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.53 42.0 3.33e-01 88.3% 41.2%
3707826 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.53 47.0 3.91e-01 98.1% 79.3%
3592886 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.52 44.0 3.55e-01 90.1% 66.9%
3958387 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.51 40.0 3.94e-01 80.9% 83.5%
4941676 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 30.0 2.98e-01 76.5% 52.6%
3176255 5086.1.1.91 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 0.51 38.0 3.37e-01 77.2% 91.7%
3268551 5054.1.1.71 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PTPLA 0.51 39.0 3.59e-01 80.2% 64.7%
D3 medium residues 361-506
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 47.0 5.32e-01 71.9% 95.4%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 49.0 4.82e-01 75.3% 78.6%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.66 48.0 5.14e-01 74.7% 91.1%
3a0oA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.66 58.0 4.29e-01 95.2% 48.5%
2ijeS00 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.65 53.0 4.44e-01 85.6% 70.0%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.64 46.0 4.58e-01 72.6% 79.7%
5jpoD02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 47.0 4.90e-01 76.7% 82.7%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.64 50.0 5.29e-01 84.2% 92.2%
1axdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 45.0 4.87e-01 74.0% 91.9%
3ismC01 1.25.40.240 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain 0.63 46.0 4.61e-01 88.4% 73.4%
1r76A00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.62 56.0 4.10e-01 97.3% 83.1%
4crwA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 51.0 4.46e-01 89.0% 58.8%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 43.0 4.48e-01 74.7% 82.7%
3vldA01 1.25.10.50 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › 0.59 49.0 3.87e-01 91.8% 43.1%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 50.0 4.49e-01 96.6% 82.0%
4qhpA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.56 51.0 3.92e-01 98.6% 70.6%
3b34A05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.56 49.0 3.83e-01 96.6% 61.5%
3qc1A01 1.25.40.540 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family 0.55 46.0 4.61e-01 91.8% 100.0%
2zttA00 6.10.140.720 Special › Helix non-globular › Helix Hairpins › 0.55 29.0 3.75e-01 72.6% 95.9%
3sl9B00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.55 47.0 4.55e-01 92.5% 89.7%
2idgA00 1.10.3480.10 Mainly Alpha › Orthogonal Bundle › TorD-like › TorD-like 0.55 35.0 3.44e-01 74.0% 57.9%
1n5dA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 3.69e-01 92.5% 87.2%
2ifuD00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 40.0 3.30e-01 92.5% 42.2%
2gnxA01 1.10.3450.30 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › 0.53 42.0 3.97e-01 89.0% 68.7%
1nxcA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.52 46.0 3.31e-01 99.3% 51.8%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3998759 109.4.1.1251 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_XPO7 0.74 63.0 3.79e-01 90.4% 16.5%
3177042 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 51.0 5.72e-01 76.0% 98.2%
4143400 109.4.1.759 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dymeclin 0.70 60.0 4.62e-01 91.8% 51.1%
3466962 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 60.0 5.19e-01 92.5% 80.5%
5031891 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.67 43.0 4.91e-01 70.5% 87.0%
4527514 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 59.0 4.68e-01 95.9% 62.5%
3644105 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.66 47.0 4.02e-01 73.3% 52.6%
3665738 109.4.1.630 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT1_TTP_bind,CNOT1_HEAT 0.65 59.0 4.35e-01 98.6% 60.8%
3261399 109.27.1.0 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.65 45.0 5.22e-01 76.0% 100.0%
3565628 109.4.1.550 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARMH3_C 0.65 57.0 4.63e-01 97.3% 67.5%
3797929 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.64 43.0 4.00e-01 87.0% 53.9%
4013285 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.64 46.0 3.86e-01 73.3% 95.0%
3327366 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.64 43.0 3.98e-01 85.6% 53.5%
3275755 109.4.1.435 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RICTOR_N 0.63 49.0 5.05e-01 81.5% 97.9%
3557559 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.63 43.0 3.90e-01 85.6% 50.0%
3840819 109.4.1.2045 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_6 0.63 43.0 3.92e-01 85.6% 51.3%
3930124 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.63 52.0 5.47e-01 91.1% 99.2%
3567486 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 51.0 3.80e-01 87.7% 46.2%
4001551 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.62 42.0 4.00e-01 85.6% 58.2%
3992675 109.4.1.313 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP20_N 0.62 52.0 4.42e-01 92.5% 77.6%
3620028 109.4.1.2636 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27635 0.61 52.0 3.23e-01 90.4% 34.1%
3617260 109.4.1.163 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N 0.61 55.0 4.27e-01 100.0% 86.6%
3681482 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.61 44.0 3.82e-01 74.7% 48.7%
3713307 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 44.0 4.36e-01 74.7% 99.4%
3797093 626.1.1.0 alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) 0.61 54.0 3.44e-01 99.3% 27.6%
3630364 109.4.1.89 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Drf_FH3,Drf_GBD 0.60 52.0 3.76e-01 95.9% 48.1%
3706764 109.4.1.226 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT1_TTP_bind 0.60 49.0 4.77e-01 88.4% 79.4%
4382701 109.4.1.1379 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30880 0.60 51.0 3.59e-01 92.5% 36.8%
4207235 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 3.49e-01 93.8% 46.2%
3715029 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 4.12e-01 100.0% 79.4%
3899509 109.4.1.87 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 0.58 46.0 3.79e-01 85.6% 64.6%
4017867 109.4.1.338 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RIC1 0.58 51.0 4.04e-01 98.6% 74.9%
4997237 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.57 39.0 4.38e-01 74.7% 91.8%
4144467 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.57 40.0 4.00e-01 88.4% 69.3%
1031024 109.4.1.241 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3458_C 0.56 50.0 3.90e-01 97.9% 70.6%
3715494 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 46.0 4.19e-01 90.4% 66.3%
3168688 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.55 43.0 4.05e-01 92.5% 67.2%
4600241 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.55 41.0 3.78e-01 78.8% 100.0%
3992534 3937.1.1.2 alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.54 41.0 3.26e-01 80.1% 79.7%
3306356 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 43.0 4.13e-01 98.6% 77.0%
3223125 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.53 42.0 3.19e-01 84.9% 62.5%
3401149 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 43.0 3.87e-01 88.4% 66.8%
3326984 3236.1.1.8 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › LrgB 0.51 41.0 2.97e-01 84.2% 67.4%
4992431 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.51 34.0 3.68e-01 80.1% 78.4%
3391650 109.4.1.1286 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 0.50 45.0 3.10e-01 100.0% 89.2%
D4 medium residues 530-610
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2dy1A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.43e-01 95.1% 38.9%
2jsnA00 2.30.42.40 Mainly Beta › Roll › Pdz3 Domain › 0.57 39.0 3.75e-01 86.4% 60.4%
2hhiA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.55 42.0 3.78e-01 84.0% 76.3%
4ijaA03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 46.0 3.88e-01 96.3% 94.0%
2wr7C01 3.90.20.10 Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › 0.55 43.0 3.07e-01 85.2% 85.4%
2eaqA00 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.53 37.0 3.68e-01 95.1% 67.4%
3cygA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.53 41.0 3.64e-01 84.0% 74.8%
2igtA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 42.0 3.04e-01 91.4% 43.1%
2aujD03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.51 29.0 3.17e-01 92.6% 67.7%
1n99A01 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.51 34.0 3.46e-01 86.4% 68.3%
3u7vA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 42.0 2.76e-01 91.4% 36.7%
2wpvE00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 34.0 2.33e-01 70.4% 26.8%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3384740 3016.1.1.24 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › UVB_sens_C 0.63 39.0 3.56e-01 85.2% 45.5%
3932224 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.61 43.0 2.87e-01 71.6% 80.0%
3429372 3343.1.1.2 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.59 45.0 2.66e-01 82.7% 13.9%
3964524 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.57 43.0 3.48e-01 85.2% 91.4%
2816274 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 41.0 3.26e-01 76.5% 81.2%
3993189 3343.1.1.2 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.56 43.0 2.62e-01 85.2% 36.2%
3885988 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.55 44.0 3.48e-01 91.4% 69.7%
2439616 6051.5.1.1 alpha duplicates or obligate multimers › Docking domains in modular polyketide synthases › Class 3 N-terminal docking domain › Class 3 N-terminal docking domain › TubC_N 0.54 36.0 3.75e-01 75.3% 74.7%
3790018 3343.1.1.2 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.54 44.0 2.69e-01 93.8% 17.1%
3615162 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 46.0 2.94e-01 100.0% 58.0%
3466238 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.53 45.0 2.86e-01 97.5% 31.1%
4939058 3457.1.1.3 alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Arc_PepC_II 0.53 45.0 3.32e-01 100.0% 98.8%
5081918 3962.1.1.0 alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit 0.53 41.0 3.01e-01 86.4% 80.0%
3601740 213.1.1.0 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.52 41.0 3.09e-01 88.9% 58.5%
4142311 109.4.1.1297 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TIMELESS, PF27570 0.52 39.0 2.36e-01 81.5% 15.7%
3957691 2002.1.1.74 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Meth_synt_2 0.51 44.0 2.95e-01 100.0% 62.4%
5010744 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.50 31.0 3.37e-01 79.0% 76.9%