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LacPavin_0818_WC40_scaffold_238879_prodigal-single.1__X__X__00134
Bact-VirLacPavin_0818_WC40_scaffold_238879_prodigal-single.1__X__X__00134
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 56-127
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.83 | 64.0 | 5.86e-01 | 80.6% | 68.9% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 62.0 | 5.58e-01 | 81.9% | 64.9% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.80 | 59.0 | 6.09e-01 | 77.8% | 97.1% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 72.0 | 6.13e-01 | 98.6% | 100.0% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 60.0 | 6.24e-01 | 80.6% | 93.9% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.79 | 58.0 | 5.37e-01 | 80.6% | 62.2% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 58.0 | 6.32e-01 | 77.8% | 100.0% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.78 | 64.0 | 5.24e-01 | 86.1% | 77.2% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 54.0 | 4.77e-01 | 80.6% | 50.5% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 58.0 | 6.20e-01 | 79.2% | 100.0% |
| 3am6A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.76 | 70.0 | 4.82e-01 | 100.0% | 90.2% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.76 | 71.0 | 4.87e-01 | 100.0% | 92.6% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 56.0 | 5.79e-01 | 80.6% | 95.5% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.75 | 65.0 | 5.73e-01 | 94.4% | 82.4% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.73 | 57.0 | 5.46e-01 | 86.1% | 97.6% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 54.0 | 4.94e-01 | 80.6% | 59.2% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.73 | 67.0 | 5.20e-01 | 100.0% | 57.1% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 55.0 | 4.95e-01 | 81.9% | 68.3% |
| 2ppqA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.72 | 53.0 | 3.71e-01 | 77.8% | 25.7% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.71 | 61.0 | 4.61e-01 | 94.4% | 41.2% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.71 | 57.0 | 5.37e-01 | 88.9% | 71.3% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 60.0 | 4.34e-01 | 97.2% | 77.4% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 63.0 | 4.64e-01 | 100.0% | 90.7% |
| 2ijqA00 | 1.10.3450.10 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like | 0.69 | 59.0 | 4.69e-01 | 97.2% | 46.9% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.68 | 49.0 | 4.08e-01 | 75.0% | 45.5% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.67 | 49.0 | 5.15e-01 | 80.6% | 91.8% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.67 | 55.0 | 5.00e-01 | 90.3% | 82.3% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 53.0 | 5.17e-01 | 100.0% | 82.5% |
| 3op0A01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.62 | 56.0 | 4.53e-01 | 100.0% | 86.8% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.61 | 55.0 | 3.48e-01 | 100.0% | 58.4% |
| 2y51A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.61 | 55.0 | 3.53e-01 | 98.6% | 33.4% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 48.0 | 3.66e-01 | 88.9% | 40.1% |
| 6umqA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.59 | 52.0 | 4.39e-01 | 95.8% | 94.8% |
| 7t7kA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.59 | 50.0 | 4.33e-01 | 98.6% | 94.1% |
| 2q83A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.58 | 50.0 | 3.51e-01 | 97.2% | 77.7% |
| 2c61A00 | 3.40.50.12240 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 49.0 | 3.07e-01 | 100.0% | 20.0% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 44.0 | 3.83e-01 | 91.7% | 100.0% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3212207 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.89 | 60.0 | 4.71e-01 | 80.6% | 37.0% |
| 3492595 | 192.29.1.11 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA | 0.86 | 66.0 | 5.34e-01 | 80.6% | 94.4% |
| 3646270 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.85 | 67.0 | 6.59e-01 | 81.9% | 89.3% |
| 4467968 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.84 | 64.0 | 5.29e-01 | 80.6% | 48.3% |
| 3653618 | 5069.1.3.69 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ETR1_N | 0.83 | 76.0 | 6.84e-01 | 98.6% | 93.7% |
| 3396277 | 192.17.1.12 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › WHEP-TRS | 0.83 | 59.0 | 6.35e-01 | 81.9% | 88.3% |
| 4192664 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.82 | 75.0 | 4.79e-01 | 98.6% | 28.4% |
| 3980428 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.82 | 64.0 | 6.33e-01 | 81.9% | 88.0% |
| 3764996 | 11.2.1.77 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › FerA | 0.81 | 62.0 | 5.15e-01 | 80.6% | 97.5% |
| 3203793 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.79 | 72.0 | 4.90e-01 | 98.6% | 82.9% |
| 3581031 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.79 | 73.0 | 5.40e-01 | 100.0% | 54.9% |
| 3794831 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.79 | 68.0 | 5.21e-01 | 94.4% | 53.8% |
| 3793583 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.79 | 72.0 | 4.47e-01 | 100.0% | 90.4% |
| 3996018 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.78 | 72.0 | 5.02e-01 | 100.0% | 46.5% |
| 3937690 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.78 | 69.0 | 4.48e-01 | 98.6% | 69.0% |
| 4964136 | 3843.1.1.6 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF | 0.78 | 69.0 | 6.50e-01 | 95.8% | 87.1% |
| 3584946 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.77 | 70.0 | 4.81e-01 | 100.0% | 42.0% |
| 3442617 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.77 | 57.0 | 4.31e-01 | 79.2% | 88.2% |
| 5052146 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.75 | 66.0 | 4.60e-01 | 98.6% | 38.5% |
| 3963421 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.75 | 68.0 | 4.84e-01 | 100.0% | 93.8% |
| 3261316 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.74 | 69.0 | 4.58e-01 | 100.0% | 88.7% |
| 3957713 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.74 | 65.0 | 5.24e-01 | 100.0% | 73.1% |
| 162110 | 616.1.1.2 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › WHEP-TRS | 0.74 | 60.0 | 5.86e-01 | 87.5% | 79.7% |
| 5023803 | 3843.1.1.36 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2107 | 0.73 | 63.0 | 5.84e-01 | 93.1% | 74.4% |
| 3788896 | 5082.1.1.0 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like | 0.71 | 62.0 | 4.57e-01 | 100.0% | 71.5% |
| 3718408 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.71 | 53.0 | 4.63e-01 | 80.6% | 52.7% |
| 4357931 | 3579.1.1.0 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J | 0.71 | 62.0 | 5.11e-01 | 95.8% | 61.6% |
| 3785087 | 5069.1.3.59 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › PF27892 | 0.71 | 59.0 | 5.07e-01 | 91.7% | 91.3% |
| 3940022 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.70 | 57.0 | 5.01e-01 | 90.3% | 70.0% |
| 4201685 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 64.0 | 5.33e-01 | 100.0% | 61.7% |
| 3990495 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 63.0 | 5.63e-01 | 100.0% | 83.0% |
| 3224084 | 5001.1.1.106 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Str | 0.69 | 62.0 | 3.99e-01 | 100.0% | 74.2% |
| 3207635 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.68 | 59.0 | 4.66e-01 | 100.0% | 59.4% |
| 3660125 | 3711.1.1.4 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 | 0.67 | 51.0 | 4.85e-01 | 81.9% | 72.9% |
| 3408518 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 60.0 | 4.98e-01 | 100.0% | 64.8% |
| 3718054 | 109.4.1.95 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 | 0.62 | 48.0 | 3.17e-01 | 91.7% | 20.7% |