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LacPavin_0818_WC40_scaffold_26136_prodigal-single.1__X__X__00084
Bact-VirLacPavin_0818_WC40_scaffold_26136_prodigal-single.1__X__X__00084
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-60
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.79 | 49.0 | 3.10e-01 | 94.6% | 14.6% |
| 2n3gA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.75 | 54.0 | 5.02e-01 | 91.1% | 61.1% |
| 1whqA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.73 | 49.0 | 4.55e-01 | 78.6% | 54.9% |
| 3e05B00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.71 | 53.0 | 3.70e-01 | 82.1% | 26.6% |
| 4dkjA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.71 | 57.0 | 3.52e-01 | 89.3% | 16.2% |
| 1o54A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.68 | 53.0 | 3.65e-01 | 83.9% | 29.0% |
| 1l3iA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.67 | 49.0 | 3.51e-01 | 82.1% | 27.6% |
| 2ql8A00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.66 | 54.0 | 4.03e-01 | 91.1% | 65.7% |
| 6vq6H01 | 1.10.287.3240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 57.0 | 3.93e-01 | 100.0% | 36.3% |
| 2yxdA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.65 | 47.0 | 3.43e-01 | 82.1% | 28.5% |
| 2c7rA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 53.0 | 3.58e-01 | 94.6% | 41.2% |
| 4mh4A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.63 | 49.0 | 4.18e-01 | 87.5% | 55.3% |
| 2ek0A00 | 3.30.110.20 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain | 0.62 | 51.0 | 4.49e-01 | 96.4% | 88.9% |
| 2bjoA02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.62 | 49.0 | 4.16e-01 | 87.5% | 55.3% |
| 3butA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.61 | 45.0 | 3.52e-01 | 80.4% | 63.2% |
| 1j5wB01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.61 | 46.0 | 3.19e-01 | 83.9% | 39.8% |
| 6tmfM00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.60 | 45.0 | 3.84e-01 | 85.7% | 61.8% |
| 3hm2A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 43.0 | 3.19e-01 | 82.1% | 28.1% |
| 3g2eB00 | 3.40.920.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 0.59 | 46.0 | 3.28e-01 | 100.0% | 27.0% |
| 3bzwF00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.58 | 49.0 | 3.23e-01 | 96.4% | 66.3% |
| 4tw1B00 | 2.70.240.10 | Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA | 0.58 | 49.0 | 3.18e-01 | 100.0% | 77.3% |
| 3aonA00 | 1.10.287.3240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 49.0 | 3.49e-01 | 100.0% | 42.0% |
| 1jpyX00 | 2.10.90.10 | Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines | 0.57 | 39.0 | 3.20e-01 | 96.4% | 35.0% |
| 5ib9A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.57 | 46.0 | 2.94e-01 | 89.3% | 18.6% |
| 4inaA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.56 | 42.0 | 3.03e-01 | 87.5% | 87.3% |
| 3ttqA03 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.56 | 41.0 | 2.75e-01 | 82.1% | 81.0% |
| 3kd9A02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.55 | 46.0 | 3.09e-01 | 98.2% | 57.4% |
| 4mx8C01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.55 | 44.0 | 2.99e-01 | 100.0% | 25.4% |
| 3ks7A02 | 2.60.120.230 | Mainly Beta › Sandwich › Jelly Rolls › | 0.55 | 45.0 | 3.31e-01 | 100.0% | 87.2% |
| 3abiA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.54 | 41.0 | 2.94e-01 | 83.9% | 89.3% |
| 2ougA00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.53 | 39.0 | 3.03e-01 | 82.1% | 34.0% |
| 1cx8A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.53 | 44.0 | 2.81e-01 | 96.4% | 62.2% |
| 3j7aV00 | 2.40.50.1000 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.53 | 34.0 | 2.68e-01 | 75.0% | 25.3% |
| 4f0aB02 | 3.30.2460.20 | Alpha Beta › 2-Layer Sandwich › Endo-n-acetylneuraminidase fold › Wnt (Wingless and Int-1), C-terminal domain | 0.53 | 40.0 | 3.84e-01 | 85.7% | 86.8% |
| 3cgbA03 | 3.30.390.30 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain | 0.53 | 41.0 | 3.38e-01 | 94.6% | 44.5% |
| 3icsA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.53 | 42.0 | 2.85e-01 | 96.4% | 53.1% |
| 6pfzD02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 41.0 | 2.82e-01 | 98.2% | 54.5% |
| 6gp1A00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.52 | 32.0 | 3.08e-01 | 73.2% | 50.8% |
| 5aj3Q00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 33.0 | 2.82e-01 | 75.0% | 33.9% |
| 1ya5T01 | 2.20.160.10 | Mainly Beta › Single Sheet › titin filament fold › titin domain like | 0.50 | 38.0 | 3.45e-01 | 87.5% | 77.4% |
ECOD (65)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4674811 | 304.48.1.17 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 | 0.76 | 53.0 | 3.24e-01 | 100.0% | 12.5% |
| 347023 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.72 | 53.0 | 3.73e-01 | 82.1% | 25.7% |
| 5037750 | 3926.1.1.1 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D | 0.71 | 58.0 | 3.98e-01 | 89.3% | 45.1% |
| None | — | 0.70 | 51.0 | 3.61e-01 | 80.4% | 27.0% | |
| 3282895 | 912.1.1.0 ↗ | few secondary structure elements › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain › HIV-1 VPU cytoplasmic domain | 0.69 | 53.0 | 3.68e-01 | 83.9% | 93.3% |
| 4009783 | 205.1.1.0 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin | 0.68 | 48.0 | 3.33e-01 | 75.0% | 27.4% |
| None | — | 0.67 | 49.0 | 3.49e-01 | 82.1% | 26.8% | |
| 4336917 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.67 | 49.0 | 3.43e-01 | 80.4% | 25.6% |
| 3905094 | 302.1.1.1 ↗ | a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C | 0.67 | 60.0 | 4.51e-01 | 100.0% | 73.3% |
| 4187457 | 4967.1.1.6 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 | 0.67 | 45.0 | 3.36e-01 | 91.1% | 30.0% |
| 3975637 | 205.1.1.50 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4, Fer4_7, Fer4_11 | 0.67 | 47.0 | 3.26e-01 | 76.8% | 26.0% |
| 3599605 | 5084.5.1.0 ↗ | beta barrels › Outer membrane meander beta-barrels › Porins › Porin | 0.66 | 43.0 | 2.75e-01 | 73.2% | 14.3% |
| 4986411 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.66 | 48.0 | 3.39e-01 | 82.1% | 26.3% |
| 3912477 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.65 | 57.0 | 3.53e-01 | 96.4% | 26.6% |
| 5078639 | 3926.1.1.1 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D | 0.64 | 56.0 | 3.87e-01 | 96.4% | 39.5% |
| None | — | 0.64 | 49.0 | 3.46e-01 | 85.7% | 27.6% | |
| 3232066 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 51.0 | 3.04e-01 | 85.7% | 13.1% |
| 5056727 | 3926.1.1.1 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D › ATP-synt_D | 0.64 | 58.0 | 3.90e-01 | 100.0% | 38.5% |
| 3982740 | 5086.1.1.190 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › OEP | 0.63 | 51.0 | 3.39e-01 | 85.7% | 99.5% |
| 5007992 | 11.1.1.51 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LEA_2 | 0.63 | 46.0 | 3.57e-01 | 80.4% | 60.0% |
| 4856794 | 304.112.1.0 ↗ | a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain | 0.62 | 44.0 | 4.05e-01 | 85.7% | 55.8% |
| 327528 | 328.1.1.2 ↗ | a+b two layers › IF3-like › AlbA-like › AlbA-like › SpoVS | 0.62 | 51.0 | 4.49e-01 | 96.4% | 88.9% |
| 3788285 | 395.1.1.4 ↗ | few secondary structure elements › Midkine-related › Midkine-related › Midkine-related › Flocculin_t3 | 0.62 | 43.0 | 4.58e-01 | 73.2% | 86.0% |
| 1411401 | 304.48.1.7 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 | 0.62 | 50.0 | 3.01e-01 | 96.4% | 37.7% |
| 5073695 | 512.1.1.1 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st | 0.61 | 55.0 | 4.51e-01 | 100.0% | 91.0% |
| 5048993 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.61 | 50.0 | 3.77e-01 | 89.3% | 58.5% |
| 5061358 | 304.55.1.14 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Y2_Tnp | 0.61 | 41.0 | 3.29e-01 | 89.3% | 35.5% |
| 4932518 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.61 | 50.0 | 4.24e-01 | 91.1% | 94.7% |
| 3513729 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 51.0 | 2.97e-01 | 100.0% | 28.6% |
| 3932435 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.61 | 49.0 | 3.18e-01 | 100.0% | 93.4% |
| 5025539 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.61 | 44.0 | 3.17e-01 | 82.1% | 25.5% |
| 3486945 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.60 | 47.0 | 3.61e-01 | 85.7% | 75.4% |
| 3190947 | 2011.1.1.0 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases | 0.60 | 48.0 | 3.00e-01 | 94.6% | 15.7% |
| 3388343 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.60 | 52.0 | 3.08e-01 | 98.2% | 54.6% |
| 3472421 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.60 | 46.0 | 3.56e-01 | 85.7% | 75.4% |
| 3728856 | 171.1.1.9 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3, Ribonucleas_3_3 | 0.60 | 50.0 | 3.42e-01 | 98.2% | 78.2% |
| 4946616 | 512.1.1.2 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd | 0.59 | 45.0 | 4.04e-01 | 89.3% | 63.3% |
| 4635290 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.59 | 52.0 | 3.09e-01 | 100.0% | 31.2% |
| 3255418 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.59 | 47.0 | 2.98e-01 | 100.0% | 16.1% |
| 4544858 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.59 | 49.0 | 2.90e-01 | 94.6% | 16.9% |
| 4126255 | 4967.1.1.25 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N | 0.59 | 51.0 | 3.22e-01 | 96.4% | 19.3% |
| 4486052 | 304.48.1.39 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › MatK_N | 0.59 | 51.0 | 3.13e-01 | 98.2% | 37.6% |
| 4538250 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.59 | 46.0 | 3.53e-01 | 87.5% | 37.0% |
| 4944561 | 512.1.1.0 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) | 0.59 | 49.0 | 4.04e-01 | 92.9% | 56.0% |
| None | — | 0.58 | 42.0 | 3.07e-01 | 82.1% | 26.1% | |
| 4629529 | 2002.1.1.420 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI, PF25918 | 0.58 | 44.0 | 2.69e-01 | 87.5% | 24.8% |
| 3967659 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.57 | 42.0 | 2.99e-01 | 82.1% | 24.6% |
| 4159896 | 2003.1.1.59 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_5 | 0.57 | 50.0 | 2.96e-01 | 96.4% | 18.9% |
| 4979109 | 2006.1.4.56 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF5615 | 0.57 | 48.0 | 3.85e-01 | 98.2% | 78.2% |
| 4973867 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.57 | 49.0 | 3.64e-01 | 100.0% | 64.5% |
| 3706357 | 298.1.1.0 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.57 | 43.0 | 2.95e-01 | 85.7% | 70.7% |
| 3717787 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.57 | 48.0 | 2.88e-01 | 92.9% | 24.7% |
| 5030500 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.57 | 45.0 | 3.40e-01 | 87.5% | 35.7% |
| 4972556 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 38.0 | 3.39e-01 | 76.8% | 47.1% |
| 5031862 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.56 | 42.0 | 3.18e-01 | 89.3% | 55.9% |
| 4979212 | 2011.1.1.0 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases | 0.55 | 46.0 | 2.88e-01 | 92.9% | 17.5% |
| 4351239 | 4967.1.1.6 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2 | 0.55 | 41.0 | 3.23e-01 | 83.9% | 41.5% |
| 3599634 | 4261.1.1.4 ↗ | a+b two layers › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA C-terminal domain-like › Slowpoke_C | 0.54 | 39.0 | 3.38e-01 | 83.9% | 57.7% |
| 4961538 | 2002.1.1.256 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MSH_C | 0.54 | 43.0 | 2.64e-01 | 92.9% | 26.5% |
| 3223309 | 11.1.1.934 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N, Arrestin_C | 0.53 | 42.0 | 2.87e-01 | 100.0% | 47.3% |
| 3474593 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.53 | 42.0 | 3.27e-01 | 100.0% | 60.6% |
| 3612987 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.53 | 42.0 | 3.22e-01 | 94.6% | 70.6% |
| 3592605 | 298.1.1.0 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.52 | 43.0 | 3.11e-01 | 96.4% | 71.4% |
| 3740450 | 328.1.1.3 ↗ | a+b two layers › IF3-like › AlbA-like › AlbA-like › Rpp20 | 0.51 | 39.0 | 3.43e-01 | 87.5% | 60.0% |
| 4940944 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.51 | 38.0 | 3.09e-01 | 87.5% | 40.0% |