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LacPavin_0818_WC40_scaffold_26136_prodigal-single.1__X__X__00196
Bact-VirLacPavin_0818_WC40_scaffold_26136_prodigal-single.1__X__X__00196
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 17-191
Domain cluster:
rep: PH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00065__D41-213
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.70 | 40.0 | 4.91e-01 | 87.4% | 86.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.70 | 39.0 | 4.92e-01 | 92.0% | 88.9% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 46.0 | 5.06e-01 | 94.9% | 81.1% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.68 | 40.0 | 4.93e-01 | 89.7% | 90.3% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.68 | 41.0 | 4.88e-01 | 92.6% | 87.4% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.68 | 41.0 | 4.68e-01 | 90.9% | 78.9% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.67 | 45.0 | 4.84e-01 | 94.9% | 78.8% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 60.0 | 5.55e-01 | 98.9% | 91.8% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 41.0 | 4.71e-01 | 94.9% | 84.0% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.65 | 44.0 | 4.26e-01 | 96.6% | 61.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 43.0 | 4.90e-01 | 94.3% | 90.6% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.64 | 40.0 | 4.68e-01 | 94.3% | 87.2% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.63 | 40.0 | 4.65e-01 | 90.9% | 90.2% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.62 | 39.0 | 4.65e-01 | 90.9% | 93.9% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 41.0 | 4.92e-01 | 92.6% | 100.0% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 40.0 | 4.75e-01 | 91.4% | 96.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 36.0 | 4.12e-01 | 94.9% | 76.3% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.61 | 39.0 | 4.18e-01 | 89.7% | 73.5% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 45.0 | 4.38e-01 | 75.4% | 92.7% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.61 | 43.0 | 4.39e-01 | 96.6% | 73.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 30.0 | 2.72e-01 | 71.4% | 35.9% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.60 | 40.0 | 4.57e-01 | 92.0% | 89.9% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 41.0 | 4.65e-01 | 96.6% | 93.1% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.60 | 46.0 | 4.64e-01 | 98.9% | 78.7% |
| 2vpzC00 | 1.20.1630.10 | Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain | 0.60 | 53.0 | 4.74e-01 | 97.1% | 97.2% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 36.0 | 3.83e-01 | 89.1% | 67.1% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 43.0 | 4.90e-01 | 85.1% | 99.2% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 42.0 | 4.74e-01 | 96.0% | 96.2% |
| 3f1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.59 | 44.0 | 4.76e-01 | 94.9% | 90.6% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 50.0 | 4.35e-01 | 100.0% | 93.3% |
| 2oc5A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 40.0 | 3.74e-01 | 72.6% | 87.4% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 50.0 | 4.24e-01 | 100.0% | 92.1% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.55 | 40.0 | 4.03e-01 | 73.1% | 93.1% |
| 4okmD00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 49.0 | 4.08e-01 | 97.7% | 83.4% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.55 | 45.0 | 4.49e-01 | 86.9% | 91.1% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 35.0 | 3.58e-01 | 84.6% | 65.1% |
| 1ciyA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.54 | 48.0 | 4.45e-01 | 97.1% | 84.6% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.53 | 34.0 | 4.21e-01 | 83.4% | 100.0% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 45.0 | 3.90e-01 | 90.3% | 67.8% |
| 4bjaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 39.0 | 3.90e-01 | 77.7% | 80.8% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 46.0 | 3.75e-01 | 95.4% | 99.1% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 41.0 | 4.09e-01 | 86.9% | 78.5% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 46.0 | 3.70e-01 | 95.4% | 78.3% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3494045 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 40.0 | 4.35e-01 | 84.0% | 70.0% |
| 5071165 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.66 | 40.0 | 4.35e-01 | 86.3% | 71.3% |
| 3463158 | 601.18.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ | 0.65 | 40.0 | 4.83e-01 | 91.4% | 90.8% |
| 3416038 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 35.0 | 3.98e-01 | 81.1% | 70.8% |
| 3899721 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.63 | 38.0 | 3.98e-01 | 85.1% | 63.0% |
| 4398872 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.63 | 39.0 | 4.05e-01 | 84.6% | 65.6% |
| 3529785 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.63 | 42.0 | 4.82e-01 | 94.3% | 93.6% |
| 3536246 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.62 | 37.0 | 4.04e-01 | 83.4% | 69.7% |
| 3548233 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.62 | 38.0 | 3.95e-01 | 87.4% | 64.2% |
| 3291574 | 192.29.1.248 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF27150 | 0.61 | 39.0 | 4.47e-01 | 90.3% | 87.2% |
| 3417891 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.61 | 38.0 | 4.05e-01 | 87.4% | 70.1% |
| 3543848 | 633.21.1.31 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PF27925 | 0.61 | 35.0 | 3.81e-01 | 86.9% | 66.9% |
| 3215358 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.60 | 43.0 | 4.15e-01 | 73.1% | 97.0% |
| 3211646 | 5001.1.1.33 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srh | 0.60 | 54.0 | 4.48e-01 | 100.0% | 91.4% |
| 3880738 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.59 | 43.0 | 4.73e-01 | 98.9% | 92.1% |
| 4958843 | 3543.1.1.13 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF308 | 0.58 | 51.0 | 5.06e-01 | 96.0% | 91.7% |
| 4019343 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.58 | 51.0 | 4.40e-01 | 98.9% | 86.4% |
| 3221013 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 52.0 | 4.43e-01 | 100.0% | 94.7% |
| 3393621 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.58 | 52.0 | 4.59e-01 | 99.4% | 79.6% |
| 3969349 | 3543.1.1.0 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel | 0.58 | 48.0 | 4.93e-01 | 89.1% | 99.4% |
| 4952079 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.57 | 43.0 | 4.13e-01 | 93.1% | 68.7% |
| 4033315 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.57 | 44.0 | 4.49e-01 | 81.1% | 93.1% |
| 3951074 | 109.3.1.160 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › EccD | 0.57 | 45.0 | 3.65e-01 | 82.3% | 58.5% |
| 3714138 | 3543.1.1.1 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › Gpr1_Fun34_YaaH | 0.57 | 51.0 | 4.83e-01 | 96.0% | 85.4% |
| 4013168 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 49.0 | 3.72e-01 | 95.4% | 81.4% |
| 4027659 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 39.0 | 3.32e-01 | 70.3% | 52.6% |
| 3951884 | 109.4.1.497 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EccD | 0.56 | 44.0 | 3.57e-01 | 82.3% | 59.1% |
| 3405044 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.55 | 49.0 | 4.34e-01 | 100.0% | 90.7% |
| 3238154 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 38.0 | 3.79e-01 | 83.4% | 68.3% |
| 3279521 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.54 | 43.0 | 4.22e-01 | 89.1% | 77.4% |
| 3638102 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.53 | 44.0 | 4.40e-01 | 89.7% | 91.4% |
| 3441289 | 3684.1.1.19 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 | 0.53 | 45.0 | 4.56e-01 | 94.9% | 88.6% |
| 5021701 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.53 | 43.0 | 3.78e-01 | 84.0% | 72.9% |
| 3715011 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.53 | 41.0 | 3.97e-01 | 98.3% | 72.8% |
| 3600367 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 45.0 | 3.90e-01 | 93.7% | 62.2% |
| 3716021 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.52 | 41.0 | 3.91e-01 | 98.3% | 71.0% |
| 3592348 | 602.1.1.0 ↗ | alpha arrays › L-aspartase middle domain-like › L-aspartase middle domain-like › L-aspartase middle domain-like | 0.52 | 45.0 | 4.06e-01 | 96.6% | 98.0% |
| 3600038 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.52 | 39.0 | 3.66e-01 | 78.3% | 92.0% |
| 4979938 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.52 | 44.0 | 3.99e-01 | 88.6% | 93.3% |
| 3676484 | 603.1.1.119 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF4220 | 0.52 | 43.0 | 4.04e-01 | 92.6% | 79.6% |
| 4420728 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.51 | 42.0 | 3.67e-01 | 88.0% | 62.2% |
| 4942127 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.51 | 42.0 | 4.21e-01 | 86.9% | 91.7% |
| 4997760 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.51 | 42.0 | 4.02e-01 | 86.9% | 95.0% |
| 3036088 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.50 | 36.0 | 3.55e-01 | 75.4% | 66.7% |