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LacPavin_0818_WC40_scaffold_407201_prodigal-single.1__X__X__00177
Bact-VirLacPavin_0818_WC40_scaffold_407201_prodigal-single.1__X__X__00177
Identity
- Kingdom:
- phage
Quality
85.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-54
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pu1A00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.89 | 46.0 | 3.76e-01 | 98.1% | 30.8% |
| 2v0uA00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.82 | 44.0 | 3.11e-01 | 100.0% | 19.2% |
| 3cjlA00 | 3.10.20.850 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3861 | 0.66 | 38.0 | 3.18e-01 | 98.1% | 35.2% |
| 2xzmZ00 | 3.30.1230.20 | Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › Ribosomal protein S21 | 0.60 | 30.0 | 2.42e-01 | 87.0% | 22.7% |
| 1yk9A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.59 | 35.0 | 2.40e-01 | 98.1% | 16.8% |
| 2oarB00 | 1.10.1200.120 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Large-conductance mechanosensitive channel, MscL; domain 1 | 0.59 | 47.0 | 3.78e-01 | 96.3% | 58.4% |
| 1t6eX01 | 2.40.70.10 | Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases | 0.58 | 40.0 | 2.80e-01 | 72.2% | 44.8% |
| 1f8vC00 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.57 | 45.0 | 2.83e-01 | 98.1% | 15.8% |
| 3zqmA00 | 6.10.140.2160 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 42.0 | 4.10e-01 | 81.5% | 76.3% |
| 2n8xA00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.56 | 47.0 | 3.26e-01 | 90.7% | 92.2% |
| 3gqhA02 | 4.10.80.40 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › succinate dehydrogenase protein domain | 0.56 | 34.0 | 3.72e-01 | 83.3% | 80.0% |
| 3gw6D02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 47.0 | 3.39e-01 | 94.4% | 86.3% |
| 1fm2B03 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.55 | 34.0 | 3.23e-01 | 72.2% | 47.0% |
| 1ciiA02 | 3.30.305.10 | Alpha Beta › 2-Layer Sandwich › Colicin Ia; domain 2 › Colicin Ia; domain 2 | 0.55 | 48.0 | 3.86e-01 | 96.3% | 77.2% |
| 1novA00 | 2.60.120.20 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 43.0 | 2.78e-01 | 96.3% | 54.4% |
| 1qgwA00 | 3.90.510.10 | Alpha Beta › Alpha-Beta Complex › Cryptophytan Phycoerythrin (Alpha-1 Chain); Chain A › Phycoerythrin alpha chain | 0.53 | 37.0 | 3.37e-01 | 74.1% | 63.2% |
| 4zg5A00 | 3.40.1210.10 | Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase | 0.53 | 31.0 | 2.04e-01 | 88.9% | 11.7% |
| 4wjmA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.52 | 40.0 | 2.63e-01 | 92.6% | 86.5% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4552869 | 2004.1.1.2 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.89 | 44.0 | 2.78e-01 | 92.6% | 12.3% |
| 3593808 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.81 | 39.0 | 3.11e-01 | 96.3% | 25.0% |
| 3606812 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.75 | 51.0 | 2.94e-01 | 70.4% | 10.6% |
| 3700769 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.73 | 38.0 | 3.03e-01 | 88.9% | 25.7% |
| 3303720 | 3336.1.1.1 ↗ | alpha complex topology › plant-specific ROP nucleotide exchanger (PRONE) domain › plant-specific ROP nucleotide exchanger (PRONE) domain › plant-specific ROP nucleotide exchanger (PRONE) domain › PRONE | 0.72 | 58.0 | 3.48e-01 | 98.1% | 12.6% |
| 4873245 | 2485.3.1.2 ↗ | a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Linocin_M18 | 0.70 | 35.0 | 2.62e-01 | 92.6% | 19.5% |
| 3214850 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.66 | 51.0 | 3.12e-01 | 85.2% | 15.7% |
| 3786528 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.65 | 52.0 | 2.85e-01 | 87.0% | 15.4% |
| 3778175 | 5052.1.1.1 ↗ | alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein › SDF | 0.63 | 48.0 | 2.76e-01 | 85.2% | 9.6% |
| 3752543 | 7.1.1.17 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain › PDZ, PDZ_6 | 0.63 | 40.0 | 3.23e-01 | 70.4% | 31.8% |
| 5041736 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 38.0 | 3.50e-01 | 70.4% | 44.0% |
| 3636298 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.62 | 51.0 | 3.45e-01 | 100.0% | 70.0% |
| 3174953 | 69.1.1.2 ↗ | beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hom_end_hint | 0.62 | 42.0 | 2.78e-01 | 70.4% | 21.0% |
| 3213645 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.61 | 43.0 | 2.83e-01 | 92.6% | 16.4% |
| 3580612 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 48.0 | 3.49e-01 | 88.9% | 47.1% |
| 3185221 | 2003.1.2.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 | 0.60 | 47.0 | 2.82e-01 | 90.7% | 47.9% |
| 3639274 | 261.1.1.1 ↗ | a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT | 0.59 | 46.0 | 2.59e-01 | 100.0% | 8.5% |
| 3372583 | 632.3.1.15 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain › PF31063 | 0.58 | 44.0 | 2.78e-01 | 79.6% | 46.5% |
| 3506781 | 922.1.1.0 ↗ | few secondary structure elements › TSP-1 type 1 repeat › TSP-1 type 1 repeat › TSP-1 type 1 repeat | 0.58 | 39.0 | 3.98e-01 | 70.4% | 94.0% |
| 4084879 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.58 | 35.0 | 3.03e-01 | 70.4% | 37.6% |
| 3927291 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.57 | 50.0 | 2.98e-01 | 96.3% | 14.7% |
| 4233683 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.56 | 45.0 | 2.98e-01 | 88.9% | 75.9% |
| 3699668 | 2004.1.1.164 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Roc | 0.56 | 49.0 | 3.16e-01 | 100.0% | 55.1% |
| 3258060 | 4357.1.1.0 ↗ | beta barrels › WWE domain › WWE domain › WWE domain | 0.56 | 36.0 | 3.41e-01 | 70.4% | 51.4% |
| 1824189 | 327.6.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › Germane | 0.56 | 46.0 | 3.50e-01 | 100.0% | 90.6% |
| 5043427 | 3010.1.1.2 ↗ | a/b three-layered sandwiches › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › Lon_C | 0.55 | 44.0 | 3.66e-01 | 88.9% | 58.6% |
| 3700547 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.55 | 49.0 | 2.77e-01 | 100.0% | 25.8% |
| 4007581 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.55 | 37.0 | 3.80e-01 | 92.6% | 76.0% |
| 5022036 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 43.0 | 3.28e-01 | 88.9% | 57.0% |
| 5066196 | 3010.1.1.0 ↗ | a/b three-layered sandwiches › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains | 0.54 | 41.0 | 3.35e-01 | 81.5% | 54.4% |
| None | — | 0.54 | 45.0 | 3.32e-01 | 100.0% | 40.6% | |
| 5078624 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.54 | 47.0 | 3.75e-01 | 96.3% | 78.1% |
| 3238872 | 11.1.1.9 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_N | 0.53 | 42.0 | 2.94e-01 | 90.7% | 56.8% |
| 4160692 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.53 | 40.0 | 2.69e-01 | 81.5% | 76.0% |
| 4983447 | 3457.1.1.3 ↗ | alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Arc_PepC_II | 0.53 | 46.0 | 2.97e-01 | 100.0% | 25.3% |
| 5054476 | 3010.1.1.0 ↗ | a/b three-layered sandwiches › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains | 0.53 | 38.0 | 3.25e-01 | 81.5% | 57.0% |
| 3387999 | 2003.2.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 | 0.52 | 43.0 | 2.85e-01 | 96.3% | 22.3% |
| 3587268 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 40.0 | 3.26e-01 | 92.6% | 95.8% |
| 4942060 | 3010.1.1.0 ↗ | a/b three-layered sandwiches › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains › C-terminal subdomain in Lon-related proteases catalytic domains | 0.52 | 37.0 | 3.21e-01 | 83.3% | 58.0% |
| 3422000 | 11.1.5.29 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Sec23_BS | 0.51 | 33.0 | 2.82e-01 | 81.5% | 33.3% |
| 3682186 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.50 | 41.0 | 3.17e-01 | 100.0% | 79.3% |
| 3815772 | 109.4.1.1580 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N, HAT_PRP39_C | 0.50 | 44.0 | 2.49e-01 | 100.0% | 13.4% |
D2
medium
residues 55-119
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1rtwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.75 | 57.0 | 3.93e-01 | 98.5% | 25.5% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 56.0 | 3.78e-01 | 87.7% | 22.9% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 51.0 | 4.03e-01 | 75.4% | 37.8% |
| 1vjxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.70 | 53.0 | 3.97e-01 | 89.2% | 34.9% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 55.0 | 5.25e-01 | 100.0% | 73.1% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 53.0 | 4.94e-01 | 90.8% | 66.3% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.68 | 55.0 | 4.81e-01 | 100.0% | 57.8% |
| 2gsqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 58.0 | 4.88e-01 | 100.0% | 57.4% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 52.0 | 3.79e-01 | 89.2% | 30.4% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.65 | 48.0 | 4.94e-01 | 100.0% | 83.6% |
| 2mx8A01 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.64 | 43.0 | 3.61e-01 | 73.8% | 39.8% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 45.0 | 4.60e-01 | 90.8% | 76.6% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.64 | 45.0 | 4.20e-01 | 100.0% | 57.6% |
| 1ax8A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 44.0 | 3.55e-01 | 73.8% | 36.2% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.63 | 53.0 | 4.70e-01 | 100.0% | 63.9% |
| 3o2tA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.63 | 45.0 | 2.93e-01 | 76.9% | 37.8% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 39.0 | 4.01e-01 | 76.9% | 65.1% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 54.0 | 3.80e-01 | 100.0% | 50.0% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 49.0 | 3.30e-01 | 90.8% | 22.8% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.59 | 43.0 | 4.00e-01 | 87.7% | 62.2% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 50.0 | 4.35e-01 | 100.0% | 62.7% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 49.0 | 3.42e-01 | 96.9% | 55.1% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.56 | 45.0 | 3.48e-01 | 92.3% | 42.3% |
| 1ygmA01 | 1.10.220.90 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Mistic | 0.53 | 41.0 | 3.71e-01 | 98.5% | 61.1% |
| 3gmfA02 | 1.10.40.110 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › | 0.53 | 37.0 | 3.29e-01 | 95.4% | 47.6% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.51 | 43.0 | 3.67e-01 | 100.0% | 79.1% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3241334 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.78 | 51.0 | 3.56e-01 | 80.0% | 21.5% |
| 3715996 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.74 | 48.0 | 5.28e-01 | 70.8% | 86.0% |
| 3286299 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.74 | 57.0 | 4.75e-01 | 90.8% | 49.1% |
| 4039014 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.74 | 57.0 | 4.76e-01 | 90.8% | 49.1% |
| 3541154 | 1078.1.1.6 ↗ | extended segments › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › Bd-type quinol oxidase transmembrane helix subunit › TMEM238 | 0.72 | 50.0 | 5.31e-01 | 81.5% | 85.5% |
| 3614667 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 48.0 | 3.00e-01 | 80.0% | 13.0% |
| 4336724 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.72 | 55.0 | 4.61e-01 | 90.8% | 49.1% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 55.0 | 3.64e-01 | 89.2% | 21.3% |
| 3927560 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.70 | 51.0 | 5.26e-01 | 87.7% | 83.3% |
| 3786136 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.70 | 53.0 | 4.44e-01 | 90.8% | 47.0% |
| 988025 | 616.1.1.5 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › T6SS_Tsi2-like | 0.68 | 55.0 | 5.28e-01 | 100.0% | 76.3% |
| 3671851 | 5086.1.1.47 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Auxin_canalis | 0.68 | 53.0 | 4.15e-01 | 84.6% | 63.7% |
| 3473135 | 601.16.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT | 0.66 | 49.0 | 4.06e-01 | 87.7% | 43.3% |
| 3476130 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.65 | 54.0 | 4.22e-01 | 100.0% | 42.9% |
| 4098488 | 192.7.1.3 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N | 0.63 | 46.0 | 4.36e-01 | 87.7% | 65.0% |
| 4285620 | 5000.4.1.5 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › PF27742 | 0.61 | 52.0 | 3.69e-01 | 100.0% | 54.4% |
| 3186724 | 109.2.1.13 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_76 | 0.60 | 52.0 | 3.19e-01 | 100.0% | 31.0% |
| 3485769 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.60 | 52.0 | 3.78e-01 | 100.0% | 40.5% |
| 3469530 | 3274.1.1.1 ↗ | extended segments › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › N-terminal region in 40S ribosomal protein rpS2 (S5p) › Ribosomal_S5 | 0.59 | 48.0 | 3.81e-01 | 90.8% | 75.7% |
| 3700672 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 50.0 | 4.27e-01 | 100.0% | 64.3% |
| 3446282 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.58 | 50.0 | 4.07e-01 | 98.5% | 64.0% |
| 4284928 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.58 | 46.0 | 2.90e-01 | 89.2% | 16.3% |
| 3875601 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.56 | 42.0 | 2.34e-01 | 84.6% | 5.5% |
| 3712097 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.56 | 49.0 | 4.39e-01 | 98.5% | 90.0% |
| 3759592 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 47.0 | 3.33e-01 | 98.5% | 65.8% |
| 3336158 | 70.3.1.0 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like | 0.55 | 48.0 | 3.70e-01 | 100.0% | 56.8% |
| 3255069 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.53 | 45.0 | 3.29e-01 | 100.0% | 64.4% |
| 3205824 | 5050.1.1.15 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like | 0.53 | 44.0 | 3.15e-01 | 98.5% | 57.4% |
| 4413986 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 43.0 | 2.91e-01 | 95.4% | 24.1% |
| 3624132 | 109.4.1.264 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RMD1-3 | 0.51 | 46.0 | 3.19e-01 | 100.0% | 36.1% |
| 3712729 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 42.0 | 2.94e-01 | 100.0% | 82.3% |
D3
medium
residues 120-186
Domain cluster:
representative
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.77 | 51.0 | 4.25e-01 | 70.1% | 40.9% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 49.0 | 4.89e-01 | 86.6% | 66.7% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 50.0 | 3.96e-01 | 80.6% | 36.7% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 53.0 | 4.97e-01 | 86.6% | 64.2% |
| 3t98B00 | 6.10.140.1350 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 51.0 | 4.69e-01 | 82.1% | 59.3% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 53.0 | 5.39e-01 | 86.6% | 80.6% |
| 3ph0C00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 32.0 | 3.64e-01 | 100.0% | 56.6% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 53.0 | 5.19e-01 | 83.6% | 74.6% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.69 | 59.0 | 3.87e-01 | 100.0% | 20.9% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 52.0 | 4.54e-01 | 83.6% | 54.6% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 48.0 | 5.13e-01 | 83.6% | 83.1% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.69 | 54.0 | 4.54e-01 | 86.6% | 51.9% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 43.0 | 4.46e-01 | 71.6% | 69.4% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.68 | 55.0 | 3.92e-01 | 89.6% | 31.2% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.68 | 50.0 | 4.86e-01 | 80.6% | 71.2% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 51.0 | 4.59e-01 | 83.6% | 69.8% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 53.0 | 5.15e-01 | 86.6% | 78.1% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 48.0 | 5.07e-01 | 82.1% | 85.0% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.66 | 49.0 | 3.96e-01 | 83.6% | 40.3% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 51.0 | 5.17e-01 | 86.6% | 83.8% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.66 | 49.0 | 5.02e-01 | 83.6% | 82.8% |
| 4ip8A00 | 1.10.132.110 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein | 0.65 | 46.0 | 4.01e-01 | 79.1% | 47.6% |
| 2btqB03 | 1.10.287.600 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 42.0 | 4.64e-01 | 73.1% | 84.9% |
| 4i0xH00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 51.0 | 4.95e-01 | 86.6% | 76.3% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.64 | 50.0 | 4.58e-01 | 86.6% | 63.3% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.64 | 50.0 | 5.00e-01 | 86.6% | 83.6% |
| 3teqB00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 52.0 | 4.52e-01 | 88.1% | 58.4% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.63 | 50.0 | 4.45e-01 | 94.0% | 59.8% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 50.0 | 3.96e-01 | 86.6% | 43.3% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 53.0 | 4.52e-01 | 98.5% | 57.8% |
| 3tbiB02 | 6.10.140.1670 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 56.0 | 4.88e-01 | 100.0% | 83.0% |
| 4lunU00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 50.0 | 3.19e-01 | 86.6% | 19.0% |
| 1iuqA01 | 1.10.1200.50 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal | 0.62 | 45.0 | 4.37e-01 | 94.0% | 69.7% |
| 1k32A03 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.62 | 42.0 | 4.17e-01 | 82.1% | 66.7% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 47.0 | 4.24e-01 | 83.6% | 60.4% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.61 | 49.0 | 3.79e-01 | 94.0% | 40.6% |
| 3rvyA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 52.0 | 4.46e-01 | 94.0% | 83.2% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.61 | 50.0 | 5.01e-01 | 97.0% | 91.2% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.59 | 52.0 | 4.37e-01 | 98.5% | 92.1% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.57 | 35.0 | 3.84e-01 | 94.0% | 75.9% |
| 1kfdA02 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.57 | 41.0 | 4.04e-01 | 80.6% | 71.8% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.56 | 44.0 | 3.83e-01 | 86.6% | 54.7% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.56 | 43.0 | 4.02e-01 | 85.1% | 70.6% |
| 4gbjC02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 49.0 | 3.88e-01 | 97.0% | 68.9% |
| 3hx3A01 | 1.10.8.20 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p | 0.55 | 38.0 | 3.81e-01 | 76.1% | 71.6% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 44.0 | 3.57e-01 | 88.1% | 71.8% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5040843 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.73 | 65.0 | 5.79e-01 | 100.0% | 72.6% |
| 3593736 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.72 | 52.0 | 4.51e-01 | 83.6% | 51.0% |
| 3492091 | 5063.1.1.16 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Romo1 | 0.71 | 57.0 | 5.86e-01 | 100.0% | 92.3% |
| 3971056 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.68 | 44.0 | 3.61e-01 | 80.6% | 37.5% |
| 3795605 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.68 | 51.0 | 3.73e-01 | 80.6% | 30.0% |
| 3839085 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.67 | 57.0 | 5.02e-01 | 98.5% | 63.0% |
| 3865528 | 101.35.1.8 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › DUF4560 | 0.67 | 42.0 | 4.46e-01 | 79.1% | 71.7% |
| 3430318 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.67 | 56.0 | 3.69e-01 | 100.0% | 20.6% |
| 1070258 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 48.0 | 5.01e-01 | 83.6% | 82.5% |
| 4189213 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.65 | 56.0 | 5.41e-01 | 95.5% | 90.7% |
| 4937584 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.65 | 55.0 | 5.30e-01 | 95.5% | 84.0% |
| 3285146 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.64 | 56.0 | 5.32e-01 | 100.0% | 90.0% |
| 4362331 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.63 | 52.0 | 3.83e-01 | 89.6% | 47.6% |
| 3515753 | 7022.1.1.0 ↗ | alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein | 0.62 | 52.0 | 3.89e-01 | 94.0% | 37.6% |
| 3980428 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.59 | 46.0 | 4.53e-01 | 88.1% | 81.3% |
| 5014266 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.56 | 43.0 | 4.14e-01 | 86.6% | 74.7% |