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LacPavin_0818_WC40_scaffold_75050_prodigal-single.1__X__X__00074

Bact-Vir

LacPavin_0818_WC40_scaffold_75050_prodigal-single.1__X__X__00074

Identity

Kingdom:
phage

Quality

58.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 92-163
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3dupA02 3.30.750.160 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.66 49.0 4.34e-01 86.1% 54.7%
1bjaA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 48.0 4.43e-01 84.7% 86.3%
1y0uA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 46.0 4.28e-01 80.6% 66.3%
1lnwF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 46.0 3.93e-01 86.1% 66.9%
2phcB01 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.59 51.0 4.89e-01 95.8% 92.8%
3ecoB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 45.0 3.77e-01 86.1% 51.9%
5zyrA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 45.0 3.60e-01 87.5% 43.7%
2ns6A00 3.30.930.30 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › 0.57 50.0 3.78e-01 100.0% 97.3%
2bgcA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 46.0 4.20e-01 91.7% 81.2%
3k4oA00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.57 36.0 2.51e-01 70.8% 17.3%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.57 41.0 3.83e-01 98.6% 60.0%
2lm0A01 1.20.1270.290 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 41.0 3.76e-01 98.6% 58.3%
2x4hA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 45.0 3.78e-01 91.7% 76.7%
3f6tA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 45.0 3.64e-01 94.4% 65.5%
5y2vC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 43.0 4.16e-01 90.3% 82.4%
2esnA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 43.0 4.06e-01 90.3% 77.5%
3szpA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 43.0 4.04e-01 91.7% 77.5%
1e25A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.52 40.0 2.76e-01 84.7% 49.3%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 41.0 2.79e-01 87.5% 34.7%
6g1dA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 43.0 4.18e-01 95.8% 89.0%
2vlaA03 1.10.10.2090 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 44.0 3.85e-01 100.0% 96.7%
4id8A00 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 36.0 3.72e-01 93.1% 80.0%
5ljmA00 1.20.58.2190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 43.0 3.28e-01 100.0% 69.0%
4hv0C00 1.10.1220.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like 0.51 39.0 3.74e-01 86.1% 96.6%
2v4jA04 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 41.0 4.01e-01 93.1% 82.1%
2yykA01 1.10.3140.10 Mainly Alpha › Orthogonal Bundle › 4-hydroxybutyryl-coa dehydratase, domain 1 › 4-hydroxybutyryl-coa dehydratase, domain 1 0.51 39.0 3.24e-01 84.7% 67.9%
7cfmR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 41.0 2.94e-01 97.2% 96.2%
2mhhA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.50 39.0 3.63e-01 87.5% 79.2%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3262307 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 39.0 4.33e-01 79.2% 83.6%
3627133 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.59 50.0 3.74e-01 95.8% 43.7%
4232234 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.59 49.0 3.67e-01 94.4% 45.3%
4560206 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.58 45.0 4.24e-01 86.1% 93.3%
3984604 7558.1.1.10 a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › GPAT_C 0.58 47.0 4.41e-01 94.4% 90.5%
3164063 101.1.9.0 alpha arrays › HTH › HTH › Putative DNA-binding domain 0.58 48.0 4.92e-01 100.0% 95.7%
4969567 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 45.0 4.36e-01 87.5% 81.2%
4987026 205.1.1.0 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin 0.58 42.0 4.00e-01 98.6% 65.9%
4028199 3860.1.1.155 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › RIFIN 0.58 39.0 2.80e-01 100.0% 23.2%
139099 7531.1.1.1 a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase 0.57 36.0 2.51e-01 70.8% 17.3%
4938467 205.1.1.33 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_10 0.57 45.0 4.59e-01 100.0% 91.4%
5062774 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.56 50.0 3.85e-01 100.0% 92.1%
5004297 4275.1.1.0 alpha arrays › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like › Hypothetical protein YqbG-like 0.55 42.0 3.74e-01 94.4% 56.2%
4310372 101.1.2.309 alpha arrays › HTH › HTH › winged helix domain › GPAT_C 0.55 46.0 3.50e-01 95.8% 48.1%
4933930 101.1.2.30 alpha arrays › HTH › HTH › winged helix domain › TrmB 0.55 46.0 4.51e-01 95.8% 85.0%
4964823 101.1.2.929 alpha arrays › HTH › HTH › winged helix domain › HVO_2833_C 0.55 44.0 3.18e-01 90.3% 67.0%
3252459 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.55 42.0 3.15e-01 84.7% 60.0%
5017858 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.55 43.0 3.46e-01 86.1% 52.4%
3267934 3525.1.1.1 alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › BET 0.54 42.0 4.41e-01 98.6% 96.9%
3501177 205.1.1.0 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin 0.54 36.0 3.86e-01 98.6% 85.0%
4050309 101.1.2.169 alpha arrays › HTH › HTH › winged helix domain › PheRS_DBD3 0.53 40.0 4.03e-01 100.0% 80.0%
4605698 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.53 48.0 4.44e-01 100.0% 79.6%
3456656 3525.1.1.1 alpha arrays › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › Bromodomain-containing protein 4 ET domain › BET 0.53 42.0 4.37e-01 98.6% 98.5%
3957678 205.1.1.20 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_15 0.53 36.0 3.80e-01 93.1% 83.3%
3718509 2004.1.1.71 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPPT 0.53 43.0 2.88e-01 100.0% 20.6%
3989440 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.53 44.0 4.13e-01 95.8% 81.1%
5013911 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 41.0 2.93e-01 86.1% 83.0%
4370713 131.1.1.4 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD,HD_assoc 0.52 46.0 2.91e-01 100.0% 19.0%
1503525 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 41.0 2.79e-01 87.5% 34.7%
3945660 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.52 42.0 4.03e-01 93.1% 82.4%
4181610 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 45.0 3.91e-01 100.0% 88.7%
4586833 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.52 47.0 4.29e-01 100.0% 78.7%
3968802 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.51 43.0 3.97e-01 98.6% 70.4%
3781664 226.1.1.0 a+b two layers › POZ domain › POZ domain › POZ domain 0.51 43.0 3.26e-01 98.6% 72.8%
4228409 109.4.1.920 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro_2 0.51 42.0 2.76e-01 97.2% 19.7%
4025595 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 40.0 4.18e-01 90.3% 95.4%
4939027 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.50 43.0 3.69e-01 98.6% 63.3%
D2 high residues 201-285
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3go5A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 41.0 4.51e-01 71.8% 72.9%
1cukA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 37.0 4.11e-01 70.6% 77.3%
3fssA01 2.30.29.120 Mainly Beta › Roll › PH-domain like › 0.58 52.0 4.47e-01 100.0% 94.1%
2eqsA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 39.0 3.91e-01 70.6% 68.5%
1z1bA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 31.0 3.55e-01 78.8% 75.4%
1yw5A01 2.20.70.10 Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › 0.53 31.0 3.50e-01 94.1% 77.8%
4rbnA01 3.10.450.330 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 35.0 3.09e-01 97.6% 47.3%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4023576 2.1.1.7 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › S1 0.64 44.0 4.27e-01 70.6% 67.4%
3875189 2.1.1.177 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › S1_RRP5 0.63 44.0 4.15e-01 75.3% 61.0%
4027740 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 43.0 4.09e-01 71.8% 60.0%
4930465 4294.1.1.0 few secondary structure elements › Trm112p-like › Trm112p-like › Trm112p-like 0.61 35.0 4.08e-01 100.0% 80.0%
3899842 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.60 40.0 4.10e-01 71.8% 69.4%
5081146 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.59 38.0 3.81e-01 71.8% 62.9%
4004358 252.2.1.3 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_1 0.59 32.0 3.84e-01 76.5% 86.0%
3207719 2002.1.1.262 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › SGT1 0.56 42.0 3.37e-01 100.0% 38.9%
3178269 206.1.2.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin 0.56 42.0 2.97e-01 81.2% 92.4%
4021277 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.55 41.0 2.69e-01 78.8% 35.9%
4179501 292.2.1.4 a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › Polo_box_2 0.55 44.0 4.03e-01 95.3% 65.0%
4991717 2488.1.1.0 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot 0.54 45.0 3.90e-01 97.6% 80.0%
3222419 331.23.1.0 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain 0.54 30.0 3.14e-01 100.0% 57.3%
4284025 206.1.2.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin 0.53 40.0 2.86e-01 81.2% 92.2%
1320090 206.1.1.24 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › HipA_C,Couple_hipA 0.51 44.0 2.87e-01 100.0% 52.9%
D3 high residues 706-861
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xmoA02 1.10.246.180 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.68 35.0 4.63e-01 87.8% 89.5%
4wz9A02 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.65 53.0 4.46e-01 85.9% 74.8%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.64 32.0 4.18e-01 97.4% 85.1%
6bmeA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 41.0 4.49e-01 96.2% 79.5%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 42.0 4.89e-01 99.4% 98.2%
5e3xA00 1.10.1370.30 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.60 51.0 3.62e-01 92.9% 50.1%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.58 31.0 3.47e-01 85.3% 64.7%
1j1vA00 1.10.1750.10 Mainly Alpha › Orthogonal Bundle › Chromosomal Replication Initiator Protein Dnaa; Chain: A; › DnaA protein, C-terminal DNA-binding domain 0.55 33.0 4.18e-01 88.5% 100.0%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.54 32.0 3.95e-01 96.8% 94.8%
3g2eB00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.53 40.0 3.82e-01 78.8% 78.4%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5024540 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.82 72.0 7.50e-01 94.9% 97.9%
3589463 2498.1.1.29 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 0.81 75.0 7.56e-01 96.2% 100.0%
None 0.72 51.0 4.43e-01 72.4% 72.2%
4952523 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.71 63.0 5.34e-01 93.6% 63.7%
5004191 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.68 53.0 4.79e-01 81.4% 85.2%
4630084 192.10.1.0 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain 0.66 33.0 4.25e-01 94.9% 82.2%
3928509 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.66 54.0 4.30e-01 85.9% 77.0%
5045924 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.65 53.0 4.85e-01 84.6% 73.0%
3239825 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.64 52.0 4.50e-01 85.9% 70.8%
3589965 2498.1.1.29 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 0.64 51.0 5.53e-01 83.3% 97.0%
3414358 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.64 54.0 4.57e-01 87.8% 69.0%
5057982 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.63 52.0 4.79e-01 85.9% 77.9%
3969025 2498.1.1.65 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › MATCAP 0.63 54.0 3.97e-01 91.7% 59.2%
5063756 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.62 51.0 4.58e-01 85.3% 71.9%
5045375 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.62 51.0 4.42e-01 86.5% 73.6%
5064807 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.61 51.0 4.48e-01 87.8% 72.0%
3291494 2498.1.1.9 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 0.60 49.0 4.17e-01 85.9% 66.1%
3224086 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.59 47.0 4.04e-01 85.9% 82.0%
3956826 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.59 33.0 3.20e-01 95.5% 49.4%
5073599 4156.1.1.1 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 0.56 38.0 4.11e-01 89.7% 82.3%
4954771 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.55 43.0 4.22e-01 82.7% 93.5%
3733319 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 33.0 3.75e-01 88.5% 81.7%
3262272 101.1.10.6 alpha arrays › HTH › HTH › Cyclin-like › RB_A 0.54 45.0 3.99e-01 90.4% 74.2%
3991252 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.53 41.0 4.02e-01 81.4% 79.4%
D4 medium residues 429-517
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fwrA01 3.40.1170.30 Alpha Beta › 3-Layer(aba) Sandwich › MutS, DNA mismatch repair protein, domain I › 0.80 47.0 5.84e-01 82.0% 93.0%
4uoiC00 3.30.160.890 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Hepatitis C virus envelope glycoprotein E1, chain C 0.76 20.0 2.70e-01 73.0% 39.2%
3va7A05 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.67 54.0 5.28e-01 91.0% 87.0%
2dy1A03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.66 45.0 4.76e-01 74.2% 81.6%
4gvbA00 3.30.70.440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Killer toxin KP6 alpha-subunit 0.65 42.0 4.45e-01 75.3% 75.3%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 49.0 5.21e-01 85.4% 100.0%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.63 49.0 4.27e-01 83.1% 91.0%
6fyqA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 48.0 3.87e-01 83.1% 51.7%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 47.0 4.27e-01 83.1% 65.6%
6torA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 50.0 4.33e-01 89.9% 60.4%
4ritA01 3.90.1150.170 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.61 48.0 3.63e-01 86.5% 37.8%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.60 49.0 4.03e-01 88.8% 95.2%
5g4iB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 49.0 4.07e-01 89.9% 53.1%
3n5mB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 48.0 3.92e-01 89.9% 50.6%
3ezjA03 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.60 37.0 4.35e-01 74.2% 98.2%
3oksA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 47.0 3.86e-01 88.8% 47.2%
3l44A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 48.0 3.88e-01 91.0% 48.1%
4q6rA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.59 46.0 4.08e-01 86.5% 58.0%
3nuiA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 3.96e-01 86.5% 59.6%
7ykvB02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.58 47.0 4.52e-01 89.9% 77.2%
1zodA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 4.07e-01 89.9% 62.4%
3dxvA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 3.98e-01 89.9% 55.9%
5i92F01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 46.0 3.78e-01 89.9% 49.4%
8dy9I01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.56 45.0 3.50e-01 89.9% 91.3%
3nx3A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 42.0 3.71e-01 89.9% 53.2%
3dodB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 44.0 3.67e-01 89.9% 51.2%
3wpwA00 3.30.1330.60 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain 0.55 38.0 3.26e-01 73.0% 89.9%
6j9eJ00 3.30.160.560 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.55 34.0 3.79e-01 85.4% 83.3%
2dmwA01 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.54 42.0 3.87e-01 84.3% 99.1%
2ehbD00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.54 39.0 3.57e-01 78.7% 84.9%
3cjnA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 45.0 3.86e-01 95.5% 62.3%
3ossD00 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 39.0 3.28e-01 78.7% 73.9%
2e9hA01 3.30.30.170 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.53 44.0 4.19e-01 97.8% 85.8%
4huzA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 36.0 3.05e-01 73.0% 73.5%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 36.0 3.81e-01 74.2% 84.0%
5b7gA00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.53 44.0 3.37e-01 100.0% 72.3%
1weyA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 37.0 3.60e-01 75.3% 67.3%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.51 40.0 3.96e-01 85.4% 80.9%
6mv2A01 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 38.0 3.74e-01 83.1% 95.1%
2cjgA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 45.0 3.78e-01 100.0% 73.4%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4991995 3696.1.1.2 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › XPB_DRD 0.81 51.0 5.87e-01 84.3% 87.7%
3470093 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.77 52.0 5.89e-01 84.3% 93.8%
3533206 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.77 51.0 5.84e-01 87.6% 93.8%
3409500 3696.1.1.1 a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › HARP 0.73 51.0 5.64e-01 87.6% 92.9%
3505715 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.68 46.0 4.86e-01 74.2% 77.5%
3738385 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.68 47.0 4.78e-01 74.2% 74.1%
4079590 306.6.1.1 a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D 0.67 55.0 5.30e-01 91.0% 87.0%
4012791 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.66 45.0 4.69e-01 74.2% 78.8%
3409366 5104.1.1.2 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › CDC45 0.65 56.0 4.81e-01 96.6% 60.7%
3998708 5104.1.1.2 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › CDC45 0.64 56.0 4.74e-01 98.9% 62.7%
3619710 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.64 56.0 4.73e-01 98.9% 61.3%
4926952 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.63 41.0 4.45e-01 74.2% 82.9%
3549717 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.62 50.0 3.83e-01 89.9% 39.1%
3926837 7577.1.1.2 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_3 0.62 50.0 3.23e-01 89.9% 19.6%
3766630 7577.1.1.2 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_3 0.62 50.0 3.20e-01 89.9% 18.7%
4581355 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.61 50.0 4.03e-01 89.9% 48.6%
3403707 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.61 49.0 4.52e-01 89.9% 72.5%
1891414 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.60 49.0 4.63e-01 89.9% 78.7%
4978015 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.60 47.0 4.61e-01 86.5% 82.0%
2092727 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.60 47.0 4.39e-01 86.5% 75.2%
2388907 5104.1.1.2 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › CDC45 0.60 50.0 4.41e-01 97.8% 61.3%
4978828 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.60 48.0 4.65e-01 88.8% 83.0%
4054900 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.59 51.0 4.25e-01 95.5% 63.9%
4945822 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.59 49.0 4.39e-01 91.0% 84.0%
2465371 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.59 47.0 4.33e-01 89.9% 72.1%
3959503 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.58 47.0 4.24e-01 91.0% 66.4%
1192836 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.58 46.0 4.28e-01 89.9% 71.7%
2870509 3016.1.1.2 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 0.58 46.0 4.34e-01 89.9% 75.2%
3740219 5104.1.1.3 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 0.58 46.0 4.09e-01 91.0% 85.0%
5074169 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.55 40.0 3.63e-01 75.3% 95.8%
3648069 223.2.1.3 a+b three layers › Profilin-like › profilin-like › profilin-like › Clat_adaptor_s 0.55 44.0 3.64e-01 88.8% 71.2%
4994703 4955.1.1.0 a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.55 44.0 4.47e-01 87.6% 96.5%
5009572 873.1.1.0 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.55 38.0 3.42e-01 73.0% 51.1%
3597966 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 46.0 4.59e-01 100.0% 91.6%
4928701 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 33.0 3.19e-01 89.9% 51.4%
4669668 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.53 39.0 3.76e-01 77.5% 69.0%
5013026 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.53 39.0 3.19e-01 77.5% 40.6%
4944313 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 39.0 3.41e-01 77.5% 92.6%
4955747 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.53 39.0 3.70e-01 79.8% 90.0%
3622943 101.1.2.28 alpha arrays › HTH › HTH › winged helix domain › eIF-5_eIF-2B 0.53 39.0 4.16e-01 80.9% 97.3%
5006953 873.1.1.12 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › PF27313 0.53 36.0 3.51e-01 70.8% 66.0%
5075473 241.6.1.2 a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits › ARPC4 0.52 44.0 3.67e-01 94.4% 80.6%
3885751 331.4.1.1 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1 0.52 38.0 3.73e-01 77.5% 94.7%
None 0.52 39.0 3.56e-01 80.9% 72.5%
4029381 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.51 43.0 3.48e-01 95.5% 75.6%
5047936 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.50 40.0 3.69e-01 88.8% 100.0%
D5 medium residues 526-654
PDB