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MF497422.1__ATB52660.1__PVS_24__00024
Bact-VirMF497422.1__ATB52660.1__PVS_24__00024
Identity
- Accession:
- MF497422 ↗
- Kingdom:
- phage
Quality
49.1
mean pLDDT
Taxonomy
TaxID: 2026084
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 47-145
D2
medium
residues 233-307
D3
medium
residues 531-619
D4
medium
residues 620-763
D5
medium
residues 909-965_1179-1193
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.67 | 57.0 | 5.30e-01 | 97.2% | 93.6% |
| 1l0oC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 45.0 | 4.94e-01 | 72.2% | 89.5% |
| 3g0oA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.63 | 55.0 | 4.69e-01 | 98.6% | 82.6% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 44.0 | 3.64e-01 | 75.0% | 73.1% |
| 3w6zA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.61 | 53.0 | 4.51e-01 | 98.6% | 93.4% |
| 3dv8A02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 48.0 | 4.72e-01 | 87.5% | 98.7% |
| 7dkaA01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.59 | 46.0 | 3.42e-01 | 84.7% | 79.5% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 43.0 | 3.83e-01 | 76.4% | 86.3% |
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.59 | 41.0 | 4.10e-01 | 73.6% | 90.7% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 42.0 | 3.85e-01 | 77.8% | 84.2% |
| 7bqiA01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.58 | 52.0 | 4.06e-01 | 98.6% | 98.7% |
| 6lpfA01 | 1.10.730.20 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › | 0.58 | 46.0 | 3.62e-01 | 88.9% | 65.6% |
| 6eboA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.57 | 46.0 | 3.04e-01 | 88.9% | 63.0% |
| 1dulA00 | 1.10.260.30 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › Signal recognition particle, SRP54 subunit, M-domain | 0.56 | 41.0 | 4.26e-01 | 94.4% | 83.8% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 42.0 | 3.85e-01 | 77.8% | 84.6% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.55 | 47.0 | 4.52e-01 | 97.2% | 89.4% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.54 | 45.0 | 3.50e-01 | 97.2% | 65.7% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 43.0 | 3.33e-01 | 86.1% | 70.1% |
| 2da7A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.54 | 41.0 | 4.20e-01 | 93.1% | 84.5% |
| 2mw8A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.53 | 39.0 | 4.06e-01 | 98.6% | 89.6% |
| 1zs3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 44.0 | 3.37e-01 | 95.8% | 46.8% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 39.0 | 3.68e-01 | 87.5% | 67.0% |
| 1gnlA01 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.51 | 45.0 | 3.65e-01 | 100.0% | 97.1% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.51 | 44.0 | 3.51e-01 | 97.2% | 68.8% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3399062 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 48.0 | 4.61e-01 | 70.8% | 87.1% |
| 4854430 | 2485.1.1.9 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › 2Fe-2S_thioredx | 0.69 | 47.0 | 4.25e-01 | 73.6% | 52.6% |
| 4452303 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 50.0 | 5.20e-01 | 77.8% | 84.6% |
| 4930318 | 101.1.4.3 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 | 0.68 | 51.0 | 4.18e-01 | 79.2% | 63.1% |
| 3244076 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.67 | 48.0 | 4.90e-01 | 90.3% | 78.6% |
| 3947132 | 101.1.1.109 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF2543 | 0.67 | 52.0 | 5.22e-01 | 95.8% | 82.7% |
| 4028797 | 1091.1.1.1 ↗ | alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › Ribosomal_60s | 0.64 | 44.0 | 4.57e-01 | 73.6% | 80.0% |
| 3798173 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 45.0 | 4.62e-01 | 76.4% | 100.0% |
| 3214189 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 46.0 | 4.04e-01 | 76.4% | 87.6% |
| 5028153 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.63 | 43.0 | 4.21e-01 | 75.0% | 63.9% |
| 3692199 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.63 | 47.0 | 3.68e-01 | 100.0% | 36.3% |
| 3507250 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 45.0 | 3.95e-01 | 76.4% | 75.2% |
| 5002559 | 2.21.1.0 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) | 0.62 | 53.0 | 4.12e-01 | 97.2% | 83.0% |
| 3505729 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 44.0 | 3.96e-01 | 76.4% | 78.0% |
| 3902140 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 42.0 | 3.89e-01 | 76.4% | 78.9% |
| 4426661 | 1091.1.1.1 ↗ | alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › Ribosomal_60s | 0.58 | 45.0 | 4.77e-01 | 95.8% | 95.4% |
| 3934800 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.58 | 40.0 | 3.78e-01 | 70.8% | 74.1% |
| 3711005 | 1091.1.1.0 ↗ | alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 | 0.57 | 42.0 | 4.56e-01 | 95.8% | 96.7% |
| 5060007 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.56 | 50.0 | 4.05e-01 | 98.6% | 97.0% |
| 3253022 | 601.44.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in anaphase-promoting complex subunit 4 › Helical bundle domain in anaphase-promoting complex subunit 4 › ANAPC4 | 0.56 | 48.0 | 3.38e-01 | 98.6% | 78.0% |
| 4940432 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 45.0 | 4.28e-01 | 94.4% | 87.8% |
| 5000806 | 251.1.1.1 ↗ | a+b two layers › FYSH domain › FYSH domain › FYSH domain › SBDS | 0.55 | 49.0 | 4.14e-01 | 95.8% | 86.1% |
| 3873240 | 378.1.1.25 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1+NfI_DNAbd_pre-N | 0.55 | 48.0 | 3.57e-01 | 97.2% | 66.5% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 46.0 | 3.64e-01 | 91.7% | 79.6% |
| 4525948 | 1091.1.1.0 ↗ | alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 | 0.54 | 39.0 | 4.26e-01 | 84.7% | 100.0% |
| 4940134 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.53 | 47.0 | 3.46e-01 | 100.0% | 62.6% |
| None | — | 0.53 | 42.0 | 2.87e-01 | 87.5% | 32.3% | |
| 3173335 | 1091.1.1.1 ↗ | alpha arrays › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › 60S acidic ribosomal protein P1/P2 › Ribosomal_60s | 0.52 | 40.0 | 4.28e-01 | 93.1% | 100.0% |
| 3305347 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.52 | 45.0 | 3.85e-01 | 93.1% | 69.1% |
D6
medium
residues 966-1046
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rvyA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 59.0 | 5.41e-01 | 97.5% | 78.5% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.68 | 42.0 | 4.17e-01 | 97.5% | 58.6% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.67 | 46.0 | 4.60e-01 | 84.0% | 68.7% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.67 | 48.0 | 4.93e-01 | 75.3% | 100.0% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.66 | 57.0 | 4.68e-01 | 97.5% | 68.6% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.65 | 45.0 | 4.59e-01 | 72.8% | 100.0% |
| 1x46A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.65 | 50.0 | 4.05e-01 | 81.5% | 92.7% |
| 5c4yA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 44.0 | 3.79e-01 | 72.8% | 69.1% |
| 2fi1A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 43.0 | 4.64e-01 | 82.7% | 89.1% |
| 4a4kA01 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.62 | 39.0 | 3.55e-01 | 96.3% | 45.1% |
| 3spcA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 52.0 | 4.55e-01 | 97.5% | 71.7% |
| 4udsA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 43.0 | 3.40e-01 | 76.5% | 52.1% |
| 1tu9A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 51.0 | 4.41e-01 | 97.5% | 69.5% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 44.0 | 3.98e-01 | 77.8% | 96.4% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.60 | 39.0 | 4.09e-01 | 97.5% | 74.0% |
| 1kxpD02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.59 | 41.0 | 4.03e-01 | 96.3% | 65.9% |
| 2nrlA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.59 | 49.0 | 4.12e-01 | 93.8% | 69.7% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.58 | 44.0 | 3.84e-01 | 100.0% | 53.3% |
| 3bhqA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 41.0 | 3.14e-01 | 74.1% | 42.6% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 49.0 | 4.22e-01 | 96.3% | 64.6% |
| 3fm9A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 46.0 | 4.67e-01 | 96.3% | 96.2% |
| 4nxtA01 | 1.10.1410.40 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › | 0.56 | 43.0 | 3.66e-01 | 86.4% | 87.6% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 42.0 | 3.61e-01 | 100.0% | 50.0% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 40.0 | 3.27e-01 | 96.3% | 40.1% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.55 | 39.0 | 3.52e-01 | 77.8% | 64.5% |
| 4me9B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 40.0 | 3.17e-01 | 81.5% | 54.8% |
| 5u56A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 38.0 | 3.52e-01 | 76.5% | 82.1% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.53 | 36.0 | 3.94e-01 | 97.5% | 89.1% |
| 5ceeA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 43.0 | 3.15e-01 | 90.1% | 68.1% |
| 4y7dA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 45.0 | 3.14e-01 | 98.8% | 93.1% |
| 1gpjA03 | 1.10.1200.70 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain | 0.52 | 35.0 | 3.53e-01 | 100.0% | 67.1% |
| 4bwrA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 44.0 | 2.75e-01 | 93.8% | 23.8% |
| 2zcxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 39.0 | 3.01e-01 | 86.4% | 62.0% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3266110 | 592.7.1.0 ↗ | alpha arrays › PWI domain-like › GIPC1 GH2 domain › GIPC1 GH2 domain | 0.68 | 60.0 | 6.11e-01 | 98.8% | 100.0% |
| 3912963 | 2002.1.1.346 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MS_TIM-barrel, MS_C | 0.67 | 57.0 | 3.46e-01 | 93.8% | 39.8% |
| 167309 | 592.2.1.3 ↗ | alpha arrays › PWI domain-like › YugE-like › YugE-like › Nab2 | 0.66 | 56.0 | 5.17e-01 | 98.8% | 75.2% |
| 3783806 | 592.1.1.2 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › Helicase_PWI | 0.65 | 51.0 | 4.74e-01 | 93.8% | 66.7% |
| 3251168 | 632.11.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DOCK_N | 0.64 | 44.0 | 4.02e-01 | 100.0% | 53.6% |
| 4273747 | 101.1.10.3 ↗ | alpha arrays › HTH › HTH › Cyclin-like › TFIIB | 0.63 | 49.0 | 4.03e-01 | 92.6% | 46.0% |
| 4926806 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 44.0 | 4.29e-01 | 74.1% | 96.7% |
| 3748471 | 4953.1.1.33 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › PF31020 | 0.62 | 52.0 | 4.66e-01 | 96.3% | 90.8% |
| 3952601 | 103.12.1.1 ↗ | alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR | 0.62 | 40.0 | 4.26e-01 | 84.0% | 77.1% |
| 5046548 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.61 | 52.0 | 3.82e-01 | 100.0% | 53.8% |
| 3731064 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.60 | 52.0 | 4.68e-01 | 100.0% | 68.2% |
| 3662390 | 632.15.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › GAUT_1 | 0.60 | 40.0 | 3.81e-01 | 100.0% | 57.9% |
| 3588719 | 564.1.1.0 ↗ | alpha arrays › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors | 0.59 | 43.0 | 4.69e-01 | 80.2% | 95.4% |
| 3971032 | 1051.1.1.1 ↗ | alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › HOASN | 0.58 | 39.0 | 3.83e-01 | 70.4% | 75.6% |
| 3212579 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.58 | 49.0 | 3.31e-01 | 93.8% | 58.0% |
| 4970630 | 109.61.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Uncharacterized protein PF2048.1 › Uncharacterized protein PF2048.1 › MJ1579 | 0.56 | 45.0 | 4.62e-01 | 95.1% | 100.0% |
| 4974407 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.56 | 42.0 | 4.11e-01 | 91.4% | 75.0% |
| 4012172 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 44.0 | 2.77e-01 | 87.7% | 19.8% |
| 4027655 | 5069.1.3.23 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DAD | 0.56 | 43.0 | 4.05e-01 | 100.0% | 67.0% |
| 3416398 | 509.1.1.0 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain | 0.54 | 43.0 | 4.49e-01 | 91.4% | 96.0% |
| 4148402 | 102.1.1.24 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › HHH_2 | 0.53 | 42.0 | 4.26e-01 | 96.3% | 88.7% |
| 3283630 | 601.7.1.18 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN_SAV_6107 | 0.53 | 43.0 | 3.95e-01 | 100.0% | 67.3% |
| 59143 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.53 | 37.0 | 3.25e-01 | 97.5% | 46.8% |
| 3187418 | 601.1.2.149 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30922 | 0.53 | 46.0 | 4.09e-01 | 96.3% | 97.4% |
| 3633261 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.52 | 38.0 | 3.82e-01 | 77.8% | 96.5% |
| 4199229 | 2007.2.2.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Phosphotyrosine protein phosphatases I-like › Ssu72 | 0.51 | 41.0 | 3.08e-01 | 96.3% | 33.5% |
| 3217001 | 109.12.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain of Ku80 › C-terminal domain of Ku80 › MAS20 | 0.51 | 43.0 | 4.33e-01 | 98.8% | 95.3% |
D7
medium
residues 1052-1118
D8
medium
residues 1194-1250
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 67.0 | 5.85e-01 | 84.2% | 59.0% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 70.0 | 6.64e-01 | 98.2% | 86.8% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 63.0 | 5.32e-01 | 89.5% | 74.7% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.78 | 69.0 | 5.44e-01 | 100.0% | 55.1% |
| 1grjA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.77 | 65.0 | 6.03e-01 | 96.5% | 78.4% |
| 2db7A01 | 6.10.250.980 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.77 | 61.0 | 6.37e-01 | 86.0% | 98.1% |
| 3ehfB01 | 6.10.250.2870 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.77 | 68.0 | 5.56e-01 | 100.0% | 58.7% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 60.0 | 5.91e-01 | 89.5% | 88.7% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.75 | 59.0 | 5.86e-01 | 87.7% | 88.1% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 65.0 | 6.53e-01 | 98.2% | 96.6% |
| 3rauA00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.75 | 61.0 | 3.75e-01 | 93.0% | 21.8% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.75 | 64.0 | 6.17e-01 | 96.5% | 85.9% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 66.0 | 6.40e-01 | 100.0% | 98.4% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 63.0 | 5.62e-01 | 98.2% | 75.9% |
| 3pyoY00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 61.0 | 5.95e-01 | 93.0% | 83.9% |
| 4rg8A04 | 1.10.287.1240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 59.0 | 5.85e-01 | 94.7% | 96.8% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 59.0 | 5.14e-01 | 89.5% | 62.4% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.71 | 61.0 | 5.67e-01 | 100.0% | 97.3% |
| 3kr9A02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 52.0 | 5.10e-01 | 96.5% | 73.8% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 57.0 | 4.83e-01 | 87.7% | 53.8% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 58.0 | 5.10e-01 | 96.5% | 62.6% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.69 | 57.0 | 4.29e-01 | 93.0% | 79.2% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 56.0 | 5.13e-01 | 93.0% | 69.2% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 56.0 | 5.13e-01 | 98.2% | 95.1% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.68 | 52.0 | 5.13e-01 | 84.2% | 91.8% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.68 | 57.0 | 5.21e-01 | 100.0% | 74.4% |
| 4abyD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 48.0 | 3.02e-01 | 75.4% | 20.6% |
| 4a4kA01 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.68 | 56.0 | 4.53e-01 | 96.5% | 47.8% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.67 | 56.0 | 5.40e-01 | 96.5% | 86.2% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 54.0 | 5.09e-01 | 100.0% | 91.8% |
| 3cegA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.64 | 49.0 | 3.20e-01 | 87.7% | 17.1% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 49.0 | 4.79e-01 | 87.7% | 90.8% |
| 4od8D00 | 6.10.140.1880 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 44.0 | 4.63e-01 | 86.0% | 84.3% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 45.0 | 4.10e-01 | 91.2% | 58.8% |
| 1k32A03 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.57 | 40.0 | 3.82e-01 | 89.5% | 61.1% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3216621 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.83 | 75.0 | 5.83e-01 | 100.0% | 86.7% |
| 3945531 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.82 | 70.0 | 6.62e-01 | 96.5% | 94.3% |
| 3981576 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.82 | 72.0 | 4.87e-01 | 100.0% | 55.1% |
| 3702347 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 69.0 | 4.87e-01 | 96.5% | 64.6% |
| 3708789 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.80 | 69.0 | 5.81e-01 | 96.5% | 60.0% |
| 3224284 | 603.3.1.0 ↗ | alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein | 0.79 | 69.0 | 4.88e-01 | 100.0% | 62.9% |
| 3773859 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.78 | 68.0 | 5.57e-01 | 100.0% | 55.2% |
| 5039854 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.77 | 68.0 | 6.19e-01 | 98.2% | 98.7% |
| 3598168 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.77 | 66.0 | 4.78e-01 | 98.2% | 36.4% |
| 4375086 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.77 | 58.0 | 5.89e-01 | 80.7% | 89.1% |
| 5048328 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 67.0 | 6.00e-01 | 100.0% | 76.2% |
| 3201591 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.75 | 58.0 | 5.24e-01 | 84.2% | 60.0% |
| 3974470 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 66.0 | 6.17e-01 | 100.0% | 94.3% |
| 3655782 | 101.1.2.598 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, POLR3C_WHD | 0.74 | 63.0 | 3.95e-01 | 96.5% | 44.3% |
| 3368426 | 109.4.1.1472 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2, Thoc2, THOC2_N | 0.74 | 64.0 | 3.49e-01 | 98.2% | 6.4% |
| 4026417 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.74 | 63.0 | 5.84e-01 | 98.2% | 76.0% |
| 3967290 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 62.0 | 5.90e-01 | 98.2% | 92.9% |
| 4174713 | 192.1.1.2 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › GreA_GreB_N | 0.73 | 60.0 | 5.51e-01 | 96.5% | 70.0% |
| 2674763 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.73 | 61.0 | 5.72e-01 | 100.0% | 97.3% |
| 3289802 | 284.1.1.0 ↗ | a+b two layers › FKBP-like › FKBP-like › FKBP-like | 0.72 | 61.0 | 3.56e-01 | 100.0% | 25.3% |
| 5045370 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 59.0 | 5.86e-01 | 98.2% | 88.3% |
| 3521328 | 192.10.1.5 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › Helical_CED_Drosha | 0.72 | 59.0 | 5.86e-01 | 93.0% | 91.7% |
| 1505665 | 192.27.1.1 ↗ | alpha bundles › Long alpha-hairpin › Helical hairpin in putative tRNA methyltransferase › Helical hairpin in putative tRNA methyltransferase › TrmK | 0.71 | 52.0 | 5.07e-01 | 96.5% | 72.6% |
| 3430567 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.70 | 57.0 | 5.61e-01 | 89.5% | 85.0% |
| 3601339 | 1008.1.1.0 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain | 0.69 | 57.0 | 4.40e-01 | 98.2% | 38.6% |
| 3618651 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.68 | 56.0 | 4.98e-01 | 94.7% | 81.2% |
| 4935077 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.66 | 54.0 | 5.04e-01 | 96.5% | 97.3% |
| 3256881 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.66 | 54.0 | 4.18e-01 | 96.5% | 37.9% |
| 3977347 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.61 | 49.0 | 3.59e-01 | 98.2% | 29.5% |
| 4303968 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.57 | 50.0 | 3.23e-01 | 98.2% | 22.3% |
| 3348608 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.57 | 46.0 | 3.90e-01 | 98.2% | 58.2% |
D9
medium
residues 1694-1787