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MF668275.1__ASZ73340.1__SEA_LUCKYBARNES_21__00022

Bact-Vir

MF668275.1__ASZ73340.1__SEA_LUCKYBARNES_21__00022

Identity

Accession:
MF668275 ↗
Kingdom:
phage

Quality

85.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 24-80
PDB
Domain cluster: representative
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 79.0 7.29e-01 100.0% 93.0%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.84 67.0 7.13e-01 94.7% 94.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.83 77.0 6.20e-01 100.0% 71.6%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 72.0 7.17e-01 93.0% 100.0%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 78.0 4.95e-01 100.0% 29.5%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 76.0 7.07e-01 100.0% 98.6%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.82 66.0 7.12e-01 84.2% 100.0%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.81 76.0 5.63e-01 100.0% 50.8%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.81 74.0 6.83e-01 98.2% 90.1%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.81 74.0 5.12e-01 100.0% 37.7%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 74.0 4.79e-01 100.0% 28.8%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.81 74.0 5.98e-01 100.0% 81.6%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 72.0 5.57e-01 100.0% 54.5%
4kzsA02 6.10.140.1870 Special › Helix non-globular › Helix Hairpins › 0.80 71.0 6.58e-01 96.5% 80.0%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.80 69.0 6.51e-01 93.0% 97.1%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.80 72.0 4.36e-01 98.2% 18.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.80 73.0 6.12e-01 98.2% 74.4%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 69.0 6.68e-01 96.5% 96.9%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 72.0 6.56e-01 98.2% 78.1%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.79 72.0 5.93e-01 100.0% 84.7%
2e5yA02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.79 59.0 6.52e-01 96.5% 100.0%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 70.0 4.72e-01 100.0% 81.3%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 64.0 6.19e-01 87.7% 87.5%
1qvrC04 6.10.140.130 Special › Helix non-globular › Helix Hairpins › 0.78 72.0 5.61e-01 100.0% 50.4%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 65.0 5.56e-01 94.7% 64.5%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.76 67.0 6.24e-01 100.0% 90.1%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 66.0 6.35e-01 94.7% 83.1%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.76 67.0 6.05e-01 98.2% 81.8%
2b5dX02 1.20.1430.10 Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain 0.75 66.0 5.15e-01 94.7% 55.3%
2p4vA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.75 69.0 6.21e-01 100.0% 76.3%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.75 66.0 5.25e-01 96.5% 52.7%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.75 65.0 6.05e-01 96.5% 83.1%
3terA00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 67.0 5.19e-01 100.0% 74.8%
3rpmA02 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.73 61.0 5.37e-01 100.0% 62.4%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.73 63.0 5.23e-01 98.2% 55.7%
1e52A00 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.72 56.0 5.69e-01 94.7% 83.9%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.72 58.0 5.82e-01 87.7% 88.1%
1l8nA03 3.90.1330.10 Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain 0.72 63.0 4.26e-01 98.2% 31.2%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 64.0 6.07e-01 100.0% 92.6%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 59.0 3.94e-01 91.2% 47.2%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.71 64.0 5.66e-01 100.0% 76.8%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.71 59.0 5.17e-01 96.5% 93.3%
1xjaB00 2.60.120.280 Mainly Beta › Sandwich › Jelly Rolls › Regulatory protein AraC 0.71 54.0 3.89e-01 87.7% 29.9%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 59.0 5.79e-01 100.0% 96.8%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 58.0 5.39e-01 96.5% 89.2%
2pybA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 57.0 4.25e-01 96.5% 40.4%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.68 58.0 4.38e-01 100.0% 51.7%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 56.0 5.07e-01 89.5% 68.0%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 59.0 5.37e-01 100.0% 85.9%
3m1cB01 3.30.390.170 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.66 48.0 3.85e-01 77.2% 78.9%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.66 51.0 4.95e-01 87.7% 83.1%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 52.0 5.34e-01 93.0% 100.0%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.64 52.0 4.69e-01 94.7% 100.0%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.64 55.0 4.90e-01 96.5% 70.7%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.63 52.0 4.39e-01 98.2% 100.0%
2lf0A01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.62 50.0 4.99e-01 94.7% 93.3%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.60 47.0 4.94e-01 93.0% 100.0%
5jxxA02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.60 40.0 3.85e-01 70.2% 59.1%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.59 49.0 4.95e-01 98.2% 93.1%
4u1cA01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.59 43.0 4.41e-01 86.0% 90.4%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 47.0 4.34e-01 100.0% 72.3%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3768858 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.86 79.0 6.49e-01 98.2% 66.3%
3318681 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 79.0 4.92e-01 100.0% 67.0%
3585224 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.86 80.0 6.83e-01 100.0% 72.9%
3925617 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.86 77.0 6.54e-01 94.7% 91.8%
3239971 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 80.0 5.11e-01 100.0% 28.7%
3713877 605.1.1.136 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Enkurin 0.85 80.0 6.48e-01 100.0% 60.2%
3609224 3602.1.1.3 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Enkurin 0.85 80.0 6.98e-01 100.0% 73.8%
3530180 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.85 77.0 6.17e-01 98.2% 61.9%
3516570 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.85 79.0 6.90e-01 100.0% 77.5%
1108845 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.85 68.0 7.35e-01 84.2% 100.0%
4026684 192.20.1.7 alpha bundles › Long alpha-hairpin › helical hairpin domain in transcriptional anti-activator ExsD › helical hairpin domain in transcriptional anti-activator ExsD › PF26729 0.85 78.0 6.23e-01 100.0% 62.9%
4623646 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.85 79.0 4.60e-01 100.0% 16.3%
3899499 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.84 74.0 5.96e-01 93.0% 65.0%
3780051 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.84 71.0 6.99e-01 91.2% 93.3%
3926706 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.84 79.0 6.35e-01 100.0% 70.0%
3786359 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.84 78.0 6.31e-01 100.0% 66.0%
4671536 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.84 72.0 5.92e-01 91.2% 55.8%
3934830 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 78.0 6.84e-01 100.0% 76.2%
4243626 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.84 76.0 4.44e-01 98.2% 15.6%
3594486 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 78.0 5.93e-01 100.0% 55.0%
3734442 192.8.1.35 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF6594 0.83 77.0 5.68e-01 98.2% 48.5%
3861615 150.1.1.190 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C 0.82 77.0 6.23e-01 100.0% 66.0%
4572974 3922.1.1.79 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C 0.82 77.0 5.93e-01 100.0% 57.4%
3217110 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.82 76.0 6.54e-01 100.0% 72.9%
3928718 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 77.0 5.58e-01 100.0% 47.1%
4193568 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.82 74.0 6.47e-01 96.5% 83.7%
3315495 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.82 75.0 6.48e-01 100.0% 78.8%
3401938 3602.1.1.14 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › DUF733 0.82 74.0 6.67e-01 98.2% 77.3%
5040661 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.81 72.0 6.70e-01 96.5% 91.4%
3832457 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 75.0 4.83e-01 100.0% 27.7%
222991 192.10.1.1 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N 0.81 76.0 6.31e-01 100.0% 71.7%
5025381 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.81 76.0 4.57e-01 100.0% 17.9%
5054469 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.81 75.0 5.99e-01 100.0% 63.8%
2394140 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.81 73.0 5.15e-01 100.0% 53.8%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.81 73.0 6.84e-01 100.0% 91.4%
3478131 109.4.1.267 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CIP2A_N 0.80 72.0 3.97e-01 98.2% 7.7%
1318696 604.25.1.1 alpha bundles › Spectrin repeat-like › Secreted protein HP1454 middle domain › Secreted protein HP1454 middle domain › HP1454-like_middle_dom 0.80 71.0 6.48e-01 96.5% 76.7%
3608116 5086.1.1.177 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 0.80 74.0 5.35e-01 100.0% 45.5%
3478399 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.80 72.0 4.72e-01 100.0% 28.3%
5057549 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.79 73.0 5.58e-01 100.0% 50.8%
1139567 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.79 72.0 5.95e-01 100.0% 60.8%
3784740 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.78 71.0 6.46e-01 100.0% 90.7%
4030059 3903.1.1.0 alpha duplicates or obligate multimers › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 › Reticulocyte binding protein 5 0.78 72.0 4.50e-01 100.0% 23.2%
5048467 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.78 68.0 4.99e-01 96.5% 37.9%
3257074 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.77 70.0 4.36e-01 100.0% 22.4%
4319295 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.77 70.0 5.63e-01 100.0% 58.1%
3847053 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.77 70.0 6.33e-01 100.0% 80.0%
5046057 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.77 67.0 6.44e-01 96.5% 87.7%
3395965 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.76 60.0 6.18e-01 86.0% 87.3%
4935668 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.76 68.0 5.16e-01 98.2% 46.9%
3705545 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.76 69.0 4.79e-01 100.0% 37.7%
4579811 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.76 68.0 5.53e-01 100.0% 92.4%
3575178 616.1.1.30 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Neur_chan_memb 0.76 67.0 6.07e-01 96.5% 78.7%
3415595 219.1.1.9 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C12 0.76 70.0 4.40e-01 100.0% 95.9%
3553833 5086.1.1.102 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp 0.75 67.0 4.61e-01 100.0% 56.8%
4225217 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.73 67.0 5.31e-01 100.0% 77.3%
3511919 3560.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 0.73 64.0 4.63e-01 96.5% 43.2%
4948755 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 60.0 5.55e-01 87.7% 71.4%
3443076 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.73 64.0 3.71e-01 100.0% 12.4%
3663990 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.72 59.0 5.58e-01 93.0% 78.6%
3585262 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 61.0 3.78e-01 100.0% 21.4%
3721627 3291.1.1.53 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CENPU 0.71 63.0 4.58e-01 100.0% 40.6%
3280086 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.70 58.0 4.20e-01 98.2% 35.0%
4300890 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.69 58.0 5.67e-01 100.0% 95.4%
3536875 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.68 57.0 3.73e-01 100.0% 21.8%
3915380 192.5.1.25 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PTHB1_hp 0.68 57.0 5.04e-01 100.0% 71.1%
3809898 6006.1.1.0 extended segments › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain 0.66 54.0 5.20e-01 91.2% 89.2%
None 0.64 53.0 3.41e-01 91.2% 21.1%
3229788 3470.1.1.0 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain 0.62 53.0 5.29e-01 98.2% 95.0%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.55 49.0 4.31e-01 100.0% 76.5%
D2 high residues 86-199
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 44.0 4.40e-01 88.6% 65.2%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.63 34.0 3.49e-01 100.0% 54.6%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.63 44.0 3.37e-01 71.9% 46.6%
4jd9G00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.60 35.0 3.46e-01 77.2% 52.5%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 34.0 4.20e-01 88.6% 89.0%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.56 28.0 3.58e-01 70.2% 81.8%
6me6B02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 43.0 3.25e-01 81.6% 33.6%
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.56 50.0 4.24e-01 100.0% 99.0%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 36.0 3.11e-01 89.5% 40.1%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 38.0 3.55e-01 70.2% 92.3%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 44.0 3.56e-01 86.8% 90.8%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 40.0 4.07e-01 77.2% 98.2%
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.53 35.0 3.70e-01 71.9% 75.2%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.53 42.0 3.57e-01 84.2% 58.6%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.53 38.0 3.79e-01 81.6% 71.8%
6kkiA01 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.52 44.0 3.18e-01 94.7% 66.2%
1cpcA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.52 40.0 3.62e-01 83.3% 75.9%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 34.0 3.16e-01 83.3% 51.7%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4217669 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.74 50.0 3.85e-01 78.1% 32.5%
4103905 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.74 52.0 3.94e-01 78.9% 32.8%
3320423 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.70 45.0 4.82e-01 71.9% 74.0%
5054557 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 39.0 4.38e-01 70.2% 68.9%
3617842 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.69 37.0 4.40e-01 75.4% 75.0%
3549234 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 54.0 5.17e-01 81.6% 80.8%
4139865 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.68 49.0 3.76e-01 82.5% 33.7%
3992094 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.67 53.0 4.54e-01 86.0% 58.4%
3575774 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.66 52.0 4.93e-01 85.1% 78.6%
4322666 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.65 59.0 4.43e-01 100.0% 73.5%
3487192 5076.1.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier 0.65 58.0 4.34e-01 100.0% 78.3%
4940500 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.65 43.0 4.35e-01 90.4% 67.0%
4324592 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.64 42.0 4.42e-01 86.8% 74.0%
3940746 5067.1.1.3 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched 0.64 49.0 4.09e-01 84.2% 46.5%
4637522 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.64 43.0 4.30e-01 75.4% 67.0%
4940986 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.63 40.0 4.38e-01 87.7% 76.8%
4579424 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.63 46.0 3.67e-01 80.7% 36.3%
4327215 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.63 44.0 4.46e-01 79.8% 71.3%
None 0.63 45.0 3.48e-01 82.5% 32.7%
4964984 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.63 39.0 4.10e-01 90.4% 69.0%
None 0.63 44.0 3.35e-01 78.9% 29.8%
4975665 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.63 49.0 3.61e-01 82.5% 47.4%
4039262 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.63 44.0 3.27e-01 78.9% 27.8%
None 0.62 44.0 3.40e-01 82.5% 33.5%
None 0.61 43.0 3.37e-01 82.5% 32.3%
None 0.61 44.0 3.37e-01 82.5% 31.9%
5056477 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.61 39.0 4.34e-01 90.4% 82.2%
3224304 4120.1.1.30 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › DUF842 0.60 39.0 4.48e-01 72.8% 89.4%
3482541 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.60 53.0 4.08e-01 100.0% 77.0%
4400622 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.59 42.0 4.40e-01 77.2% 82.9%
3990896 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.59 46.0 3.76e-01 85.1% 79.5%
4939361 3896.1.2.0 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase 0.58 42.0 3.82e-01 100.0% 56.7%
5045723 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 42.0 3.50e-01 75.4% 67.8%
3940867 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.58 41.0 4.48e-01 74.6% 90.5%
3547935 3204.1.1.0 extended segments › N-terminal regulatory segment of carnitine palmitoyltransferase 1A › N-terminal regulatory segment of carnitine palmitoyltransferase 1A › N-terminal regulatory segment of carnitine palmitoyltransferase 1A 0.56 41.0 4.18e-01 75.4% 97.3%
3394243 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 43.0 3.53e-01 85.1% 72.3%
4077250 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 44.0 3.53e-01 88.6% 70.2%
3551992 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 44.0 3.62e-01 90.4% 85.0%
3770290 4177.1.1.41 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EVC2_like 0.52 45.0 3.81e-01 95.6% 66.7%
5032686 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 40.0 3.37e-01 84.2% 95.4%