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MG592551.1__AUR93204.1__NVP1185O_17__00017
Bact-VirMG592551.1__AUR93204.1__NVP1185O_17__00017
Identity
- Accession:
- MG592551 ↗
- Kingdom:
- phage
Quality
84.9
mean pLDDT
Taxonomy
TaxID: 1881392
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 360-486
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jd9G00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.61 | 36.0 | 3.76e-01 | 91.3% | 61.7% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 43.0 | 3.29e-01 | 79.5% | 59.6% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 31.0 | 3.30e-01 | 70.9% | 60.9% |
| 2r0cA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.54 | 47.0 | 3.81e-01 | 98.4% | 77.6% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 36.0 | 3.37e-01 | 71.7% | 82.3% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3611907 | 5001.1.1.18 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF3522 | 0.60 | 46.0 | 3.99e-01 | 96.1% | 52.0% |
| 4318836 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.58 | 50.0 | 4.00e-01 | 96.1% | 97.0% |
| 5062612 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.58 | 36.0 | 3.17e-01 | 77.2% | 42.8% |
| 3770290 | 4177.1.1.41 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EVC2_like | 0.57 | 39.0 | 3.44e-01 | 70.9% | 65.1% |
| 3465481 | 148.1.3.14 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › ORC4_C | 0.57 | 43.0 | 4.30e-01 | 100.0% | 77.7% |
| 3275200 | 5050.1.1.76 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like, MFS_1 | 0.52 | 46.0 | 3.17e-01 | 99.2% | 69.9% |
| 3284826 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.51 | 45.0 | 3.75e-01 | 96.9% | 78.2% |
| 4937823 | 3558.1.1.0 ↗ | alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain | 0.51 | 29.0 | 3.23e-01 | 86.6% | 71.0% |
| 3882129 | 5001.1.1.126 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF25987 | 0.51 | 43.0 | 3.40e-01 | 97.6% | 44.6% |
| 3291075 | 5067.1.1.6 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › YibE_F | 0.50 | 45.0 | 3.63e-01 | 98.4% | 58.4% |
| 3589113 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.50 | 44.0 | 3.40e-01 | 97.6% | 65.1% |
| 3666345 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.50 | 36.0 | 3.44e-01 | 74.0% | 88.7% |
D2
medium
residues 63-159
Domain cluster:
representative
CATH (66)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 58.0 | 4.52e-01 | 75.3% | 74.0% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 58.0 | 4.62e-01 | 76.3% | 44.8% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.78 | 57.0 | 5.54e-01 | 84.5% | 69.8% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.77 | 55.0 | 5.46e-01 | 76.3% | 71.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.77 | 68.0 | 6.50e-01 | 94.8% | 100.0% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.75 | 70.0 | 5.33e-01 | 100.0% | 50.2% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 56.0 | 4.74e-01 | 78.4% | 81.1% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 55.0 | 4.09e-01 | 78.4% | 34.7% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 54.0 | 3.88e-01 | 77.3% | 31.7% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 60.0 | 5.87e-01 | 89.7% | 93.5% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 52.0 | 3.90e-01 | 75.3% | 50.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 53.0 | 4.68e-01 | 77.3% | 58.3% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.71 | 38.0 | 4.47e-01 | 78.4% | 74.6% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.71 | 46.0 | 4.60e-01 | 84.5% | 63.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 56.0 | 5.72e-01 | 85.6% | 100.0% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.71 | 49.0 | 4.39e-01 | 71.1% | 54.1% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 51.0 | 5.16e-01 | 75.3% | 90.6% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 48.0 | 4.77e-01 | 76.3% | 66.3% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 49.0 | 5.46e-01 | 78.4% | 97.3% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.69 | 50.0 | 4.50e-01 | 75.3% | 90.8% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 58.0 | 5.73e-01 | 91.8% | 95.0% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.68 | 52.0 | 4.71e-01 | 81.4% | 66.9% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.68 | 42.0 | 4.50e-01 | 77.3% | 71.8% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 49.0 | 4.29e-01 | 76.3% | 50.3% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 5.10e-01 | 86.6% | 76.9% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.67 | 47.0 | 4.62e-01 | 76.3% | 66.4% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.67 | 51.0 | 4.74e-01 | 85.6% | 63.5% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.67 | 59.0 | 4.14e-01 | 100.0% | 83.1% |
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 49.0 | 5.06e-01 | 80.4% | 82.4% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 47.0 | 4.63e-01 | 78.4% | 68.9% |
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 49.0 | 5.47e-01 | 92.8% | 98.7% |
| 1n4kA02 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.66 | 47.0 | 4.10e-01 | 89.7% | 49.3% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.66 | 51.0 | 4.86e-01 | 82.5% | 72.3% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 46.0 | 4.99e-01 | 76.3% | 90.9% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 45.0 | 4.98e-01 | 70.1% | 90.7% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 42.0 | 3.79e-01 | 72.2% | 48.5% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 44.0 | 5.04e-01 | 70.1% | 94.4% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 43.0 | 3.47e-01 | 87.6% | 34.6% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.65 | 49.0 | 4.57e-01 | 79.4% | 72.3% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.65 | 50.0 | 5.21e-01 | 83.5% | 94.4% |
| 2fefA01 | 1.20.1440.70 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like | 0.65 | 53.0 | 4.89e-01 | 89.7% | 92.0% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 55.0 | 4.88e-01 | 92.8% | 99.3% |
| 1chuA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.65 | 48.0 | 5.04e-01 | 86.6% | 87.5% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 54.0 | 4.79e-01 | 91.8% | 71.2% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.64 | 50.0 | 4.61e-01 | 84.5% | 67.7% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.64 | 46.0 | 4.28e-01 | 78.4% | 58.9% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.64 | 48.0 | 5.01e-01 | 87.6% | 87.6% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 54.0 | 5.26e-01 | 91.8% | 88.0% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.64 | 54.0 | 5.61e-01 | 90.7% | 100.0% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 51.0 | 4.08e-01 | 87.6% | 94.9% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.63 | 40.0 | 4.57e-01 | 73.2% | 87.3% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 53.0 | 4.79e-01 | 90.7% | 70.8% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.63 | 46.0 | 4.80e-01 | 76.3% | 84.4% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.61 | 49.0 | 4.42e-01 | 86.6% | 64.7% |
| 7csoA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.60 | 52.0 | 4.02e-01 | 95.9% | 56.4% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.60 | 48.0 | 4.18e-01 | 86.6% | 66.2% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 42.0 | 4.32e-01 | 72.2% | 81.3% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 50.0 | 4.33e-01 | 91.8% | 96.0% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.59 | 50.0 | 4.15e-01 | 92.8% | 80.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.59 | 50.0 | 4.85e-01 | 93.8% | 99.1% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.59 | 42.0 | 4.67e-01 | 75.3% | 100.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 47.0 | 4.20e-01 | 88.7% | 94.4% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 44.0 | 3.87e-01 | 84.5% | 94.0% |
| 1gs0A01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.57 | 45.0 | 4.05e-01 | 83.5% | 73.6% |
| 2wglA00 | 1.10.4190.10 | Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF | 0.56 | 40.0 | 3.22e-01 | 76.3% | 74.6% |
| 7f16R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 43.0 | 3.17e-01 | 89.7% | 62.8% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3363015 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.81 | 58.0 | 5.06e-01 | 74.2% | 55.0% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.79 | 58.0 | 4.72e-01 | 76.3% | 43.5% |
| 3894567 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.77 | 57.0 | 4.52e-01 | 77.3% | 42.6% |
| 222846 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.77 | 57.0 | 5.83e-01 | 77.3% | 83.9% |
| 3954313 | 150.5.1.52 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE | 0.77 | 56.0 | 5.70e-01 | 76.3% | 78.9% |
| 3584480 | 3835.1.1.0 ↗ | alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein | 0.75 | 54.0 | 4.50e-01 | 76.3% | 45.3% |
| 5007128 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 55.0 | 3.65e-01 | 76.3% | 95.1% |
| 3792078 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 50.0 | 4.73e-01 | 76.3% | 58.3% |
| 4886107 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.74 | 64.0 | 6.35e-01 | 99.0% | 92.0% |
| 4635167 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.74 | 61.0 | 5.79e-01 | 88.7% | 80.0% |
| 3613932 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.74 | 55.0 | 5.14e-01 | 76.3% | 79.1% |
| 3953227 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.74 | 54.0 | 5.34e-01 | 76.3% | 78.0% |
| 3695649 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.74 | 54.0 | 5.01e-01 | 77.3% | 63.4% |
| 4983118 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.73 | 54.0 | 5.47e-01 | 77.3% | 77.9% |
| 4210642 | 3755.1.1.12 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ | 0.73 | 54.0 | 4.87e-01 | 77.3% | 60.8% |
| 3423402 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.73 | 52.0 | 5.49e-01 | 77.3% | 83.5% |
| 3628140 | 3826.1.1.43 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Med14 | 0.72 | 50.0 | 4.80e-01 | 74.2% | 62.7% |
| 3294747 | 3755.3.1.7 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF677 | 0.71 | 52.0 | 4.61e-01 | 76.3% | 91.1% |
| 3482273 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.71 | 51.0 | 4.90e-01 | 78.4% | 66.1% |
| 4019479 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.70 | 64.0 | 4.42e-01 | 100.0% | 38.1% |
| 3248284 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.70 | 61.0 | 5.96e-01 | 93.8% | 94.3% |
| 3952510 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.70 | 48.0 | 5.33e-01 | 73.2% | 92.0% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.69 | 63.0 | 4.38e-01 | 100.0% | 43.9% |
| 3215342 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.69 | 51.0 | 5.14e-01 | 77.3% | 77.9% |
| 3548646 | 604.6.1.52 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › Med14 | 0.69 | 48.0 | 4.78e-01 | 71.1% | 71.0% |
| 3841645 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.69 | 58.0 | 5.80e-01 | 91.8% | 98.0% |
| 3598650 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.69 | 50.0 | 5.12e-01 | 75.3% | 78.9% |
| 3915818 | 4207.1.1.35 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med14 | 0.68 | 49.0 | 4.86e-01 | 74.2% | 75.0% |
| 3474600 | 4207.1.2.48 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med14 | 0.68 | 47.0 | 4.72e-01 | 72.2% | 71.0% |
| 223985 | 3600.1.1.1 ↗ | alpha bundles › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › YlqD | 0.68 | 49.0 | 4.30e-01 | 76.3% | 50.7% |
| 3760483 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 61.0 | 4.89e-01 | 100.0% | 78.9% |
| 3267769 | 192.15.1.107 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Med14 | 0.67 | 42.0 | 4.28e-01 | 75.3% | 64.2% |
| 4967956 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.67 | 56.0 | 5.39e-01 | 91.8% | 100.0% |
| 3903775 | 192.8.1.419 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF27603 | 0.66 | 57.0 | 5.31e-01 | 92.8% | 88.3% |
| 3792010 | 604.1.1.105 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1_2 | 0.66 | 59.0 | 5.82e-01 | 97.9% | 98.1% |
| 3973571 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.66 | 49.0 | 4.63e-01 | 77.3% | 99.1% |
| 3266812 | 3291.1.1.211 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › EMC3_TMCO1 | 0.66 | 46.0 | 3.84e-01 | 86.6% | 43.1% |
| 4992337 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.66 | 52.0 | 4.58e-01 | 86.6% | 59.3% |
| 3966574 | 633.9.1.1 ↗ | alpha bundles › Bromodomain-like › PA2201 N-terminal domain-like › PA2201 N-terminal domain-like › PA2201_N | 0.65 | 53.0 | 4.97e-01 | 90.7% | 92.8% |
| 4992256 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 53.0 | 5.33e-01 | 88.7% | 97.0% |
| 3467802 | 603.1.1.226 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26740 | 0.64 | 52.0 | 4.52e-01 | 92.8% | 57.9% |
| 3615158 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.63 | 49.0 | 4.13e-01 | 87.6% | 51.0% |
| 3927285 | 1008.1.1.51 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › Med14 | 0.62 | 43.0 | 4.10e-01 | 72.2% | 87.8% |
| 2142296 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.59 | 44.0 | 4.39e-01 | 77.3% | 78.6% |
| 3725482 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.56 | 43.0 | 4.05e-01 | 82.5% | 74.2% |
| 3436406 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.55 | 44.0 | 3.85e-01 | 83.5% | 92.9% |
D3
medium
residues 160-235
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 58.0 | 5.13e-01 | 92.1% | 82.6% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.67 | 52.0 | 4.60e-01 | 84.2% | 85.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.67 | 60.0 | 5.29e-01 | 98.7% | 80.9% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.67 | 51.0 | 4.37e-01 | 88.2% | 50.8% |
| 5jqkA03 | 3.90.230.10 | Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily | 0.66 | 46.0 | 3.14e-01 | 89.5% | 19.1% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 54.0 | 4.65e-01 | 90.8% | 81.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 54.0 | 4.85e-01 | 93.4% | 82.6% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 52.0 | 3.49e-01 | 86.8% | 28.6% |
| 5mlc900 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 54.0 | 4.90e-01 | 93.4% | 80.4% |
| 4s2rQ03 | 3.90.230.10 | Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily | 0.65 | 58.0 | 3.87e-01 | 100.0% | 95.6% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.63 | 44.0 | 4.81e-01 | 81.6% | 85.9% |
| 1gwiA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.63 | 55.0 | 3.49e-01 | 98.7% | 67.9% |
| 2va8A03 | 1.10.3380.30 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › | 0.63 | 56.0 | 4.04e-01 | 100.0% | 64.4% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.63 | 40.0 | 4.30e-01 | 81.6% | 76.6% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.63 | 54.0 | 4.04e-01 | 96.1% | 53.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 55.0 | 4.65e-01 | 96.1% | 61.5% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.62 | 48.0 | 3.98e-01 | 81.6% | 87.8% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 54.0 | 4.24e-01 | 97.4% | 65.2% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.60 | 52.0 | 4.32e-01 | 98.7% | 77.3% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 51.0 | 4.01e-01 | 100.0% | 45.8% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.60 | 53.0 | 4.17e-01 | 100.0% | 96.3% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 52.0 | 4.19e-01 | 97.4% | 67.8% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 54.0 | 4.76e-01 | 100.0% | 75.2% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 52.0 | 4.13e-01 | 97.4% | 65.8% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.59 | 51.0 | 3.84e-01 | 96.1% | 46.7% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 50.0 | 4.06e-01 | 97.4% | 73.3% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 51.0 | 4.11e-01 | 98.7% | 57.5% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 50.0 | 4.50e-01 | 93.4% | 81.6% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.58 | 53.0 | 4.29e-01 | 100.0% | 58.3% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 50.0 | 4.31e-01 | 94.7% | 70.9% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.58 | 50.0 | 4.63e-01 | 96.1% | 83.5% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 50.0 | 4.03e-01 | 97.4% | 64.9% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.58 | 41.0 | 4.47e-01 | 77.6% | 90.5% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 49.0 | 3.76e-01 | 94.7% | 67.6% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 46.0 | 4.26e-01 | 89.5% | 76.5% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.56 | 50.0 | 3.90e-01 | 100.0% | 80.4% |
| 7ru9C01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 45.0 | 3.11e-01 | 100.0% | 25.1% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.55 | 45.0 | 3.70e-01 | 92.1% | 52.0% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 41.0 | 3.92e-01 | 78.9% | 93.3% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.55 | 49.0 | 3.49e-01 | 100.0% | 33.3% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 47.0 | 3.71e-01 | 98.7% | 65.1% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.53 | 44.0 | 3.74e-01 | 90.8% | 68.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 45.0 | 3.87e-01 | 98.7% | 57.8% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 43.0 | 3.88e-01 | 92.1% | 76.4% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.51 | 42.0 | 4.10e-01 | 96.1% | 85.2% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3189978 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.84 | 60.0 | 5.17e-01 | 75.0% | 50.4% |
| 4237044 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.79 | 72.0 | 4.85e-01 | 100.0% | 66.7% |
| 4231910 | 4168.1.1.1 ↗ | alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › HAMP | 0.78 | 54.0 | 4.76e-01 | 72.4% | 51.8% |
| 4989360 | 310.2.1.84 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › HAMP | 0.77 | 56.0 | 4.66e-01 | 76.3% | 46.2% |
| 3801151 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.74 | 54.0 | 3.92e-01 | 76.3% | 30.7% |
| 4236667 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.70 | 60.0 | 4.13e-01 | 93.4% | 54.5% |
| 4360452 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.69 | 59.0 | 4.54e-01 | 94.7% | 50.3% |
| 5035080 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.69 | 59.0 | 4.63e-01 | 93.4% | 85.2% |
| 3414672 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.68 | 56.0 | 4.25e-01 | 92.1% | 82.1% |
| 4623683 | 316.1.1.0 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase | 0.68 | 60.0 | 4.46e-01 | 100.0% | 83.0% |
| 4018207 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.68 | 57.0 | 4.48e-01 | 93.4% | 58.8% |
| 3845824 | 106.1.1.10 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › BCD_RFX | 0.68 | 60.0 | 4.60e-01 | 98.7% | 47.1% |
| 3412555 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.68 | 53.0 | 4.73e-01 | 98.7% | 59.1% |
| 5070237 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.67 | 57.0 | 5.41e-01 | 96.1% | 87.8% |
| 3913373 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 57.0 | 4.87e-01 | 94.7% | 68.3% |
| 3963163 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 53.0 | 4.27e-01 | 92.1% | 63.2% |
| 3967249 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 53.0 | 3.96e-01 | 89.5% | 74.2% |
| 3535566 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 54.0 | 4.60e-01 | 94.7% | 64.8% |
| 3392851 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 55.0 | 4.08e-01 | 97.4% | 42.0% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.63 | 44.0 | 3.81e-01 | 80.3% | 46.2% |
| 3913790 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 55.0 | 4.82e-01 | 100.0% | 66.1% |
| 3476064 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.62 | 43.0 | 3.74e-01 | 80.3% | 45.8% |
| 3503661 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.62 | 56.0 | 4.28e-01 | 98.7% | 55.3% |
| 3997555 | 192.15.1.2 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r | 0.62 | 45.0 | 4.17e-01 | 84.2% | 60.0% |
| 3061928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 53.0 | 3.98e-01 | 96.1% | 60.3% |
| 4998043 | 633.29.1.13 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 › DUF2096_N | 0.61 | 54.0 | 4.94e-01 | 96.1% | 83.0% |
| 3725377 | 192.15.1.44 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF6604 | 0.61 | 45.0 | 4.24e-01 | 82.9% | 65.6% |
| 3347110 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.60 | 52.0 | 3.62e-01 | 93.4% | 43.6% |
| 3438984 | 192.15.1.176 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Cornichon | 0.60 | 52.0 | 5.06e-01 | 96.1% | 91.6% |
| 3798366 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 51.0 | 3.68e-01 | 96.1% | 51.1% |
| 3670746 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.60 | 46.0 | 3.90e-01 | 81.6% | 86.7% |
| 3927056 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.59 | 51.0 | 3.73e-01 | 94.7% | 90.0% |
| 4972684 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.59 | 50.0 | 4.40e-01 | 92.1% | 72.7% |
| 3490690 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 51.0 | 4.36e-01 | 96.1% | 59.2% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.59 | 52.0 | 4.25e-01 | 98.7% | 53.8% |
| 3697705 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.59 | 53.0 | 3.93e-01 | 98.7% | 57.4% |
| 4032384 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.59 | 47.0 | 4.71e-01 | 96.1% | 85.0% |
| 3574626 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 44.0 | 3.57e-01 | 80.3% | 49.3% |
| 3201057 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.58 | 48.0 | 3.62e-01 | 90.8% | 76.2% |
| 3723174 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.58 | 44.0 | 4.47e-01 | 80.3% | 85.3% |
| 3591222 | 604.1.1.198 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › BAG | 0.58 | 47.0 | 4.43e-01 | 93.4% | 80.0% |
| 3613133 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.57 | 48.0 | 4.68e-01 | 100.0% | 83.5% |
| 3572847 | 604.1.1.162 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4716 | 0.57 | 50.0 | 4.33e-01 | 94.7% | 71.3% |
| 3940375 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.57 | 46.0 | 3.60e-01 | 92.1% | 56.1% |
| 3828970 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.57 | 46.0 | 4.24e-01 | 85.5% | 81.1% |
| 4988178 | 633.29.1.0 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 | 0.57 | 49.0 | 4.60e-01 | 97.4% | 82.1% |
| 3708789 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.57 | 43.0 | 3.99e-01 | 80.3% | 66.3% |
| 4153446 | 604.12.1.4 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 | 0.57 | 44.0 | 3.96e-01 | 85.5% | 82.7% |
| 3934654 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.56 | 46.0 | 3.52e-01 | 89.5% | 73.9% |
| 3879381 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.56 | 49.0 | 3.96e-01 | 100.0% | 80.6% |
| 4032823 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 45.0 | 4.52e-01 | 96.1% | 86.3% |
| 3770274 | 603.1.1.198 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF4716 | 0.54 | 49.0 | 4.55e-01 | 98.7% | 83.2% |
| 4236831 | 604.6.1.50 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 | 0.54 | 46.0 | 4.53e-01 | 93.4% | 88.7% |
| 3991608 | 109.4.1.102 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › WAPL | 0.54 | 49.0 | 3.09e-01 | 100.0% | 32.2% |
| 3785610 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.53 | 43.0 | 3.56e-01 | 88.2% | 79.3% |
| 3678146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.53 | 47.0 | 3.83e-01 | 98.7% | 59.3% |
| 3517330 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.51 | 44.0 | 3.30e-01 | 100.0% | 96.7% |
D4
medium
residues 487-543
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3htmA02 | 6.10.250.3030 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 34.0 | 3.96e-01 | 80.7% | 77.5% |
| 6v88A00 | 3.30.710.10 | Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A | 0.61 | 40.0 | 3.16e-01 | 84.2% | 33.6% |
| 2k4mA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 39.0 | 2.94e-01 | 70.2% | 73.9% |
| 1byiA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 41.0 | 2.84e-01 | 80.7% | 68.8% |
| 4hv0C00 | 1.10.1220.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like | 0.53 | 42.0 | 3.68e-01 | 87.7% | 88.8% |
| 3w3sA02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.53 | 41.0 | 2.55e-01 | 86.0% | 76.0% |
| 1sw6A00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.53 | 43.0 | 2.81e-01 | 89.5% | 36.2% |
| 1gnlA01 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 36.0 | 2.85e-01 | 73.7% | 67.6% |
| 1dj8A00 | 1.10.890.10 | Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › HNS-dependent expression A | 0.52 | 39.0 | 3.61e-01 | 100.0% | 62.0% |
| 2ltuA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.51 | 34.0 | 3.42e-01 | 70.2% | 77.4% |
| 1uelB00 | 6.10.300.40 | Special › Helix non-globular › cAMP-dependent Protein Kinase, Chain A › | 0.51 | 34.0 | 3.68e-01 | 77.2% | 83.3% |
| 2ld7A00 | 6.10.160.20 | Special › Helix non-globular › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.51 | 36.0 | 3.17e-01 | 78.9% | 46.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3640926 | 109.4.1.1274 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, PPR_long | 0.59 | 40.0 | 2.44e-01 | 70.2% | 27.7% |
| 3852697 | 144.1.1.5 ↗ | alpha arrays › PGBD-like › PGBD-like › PGBD-like › PLAC8 | 0.53 | 38.0 | 3.34e-01 | 77.2% | 100.0% |
| 3656957 | 148.1.3.42 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › RCF1-5-like_lid | 0.53 | 35.0 | 3.18e-01 | 100.0% | 48.8% |
| 4962041 | 304.55.1.0 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains | 0.52 | 36.0 | 2.52e-01 | 80.7% | 21.0% |