Back to structures

MG835450.1__AUV61415.1__phiPsal1_006__00006

Bact-Vir

MG835450.1__AUV61415.1__phiPsal1_006__00006

Identity

Accession:
MG835450 ↗
Kingdom:
phage

Quality

80.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 126-240
PDB
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 43.0 5.25e-01 99.1% 97.3%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.61 36.0 3.96e-01 80.0% 70.5%
3hi0A02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.60 39.0 3.36e-01 93.9% 40.4%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 32.0 3.30e-01 95.7% 56.4%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 49.0 4.03e-01 93.9% 90.1%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.56 44.0 3.55e-01 84.3% 70.5%
8ex5A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 49.0 4.05e-01 100.0% 91.4%
3u4qA02 1.10.274.50 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › 0.56 42.0 3.89e-01 98.3% 61.3%
1y7yA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.55 31.0 3.79e-01 80.0% 89.9%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 47.0 4.34e-01 95.7% 71.3%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 49.0 4.36e-01 100.0% 69.6%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.55 38.0 3.88e-01 93.0% 72.6%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.54 37.0 3.99e-01 77.4% 83.5%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 4.33e-01 75.7% 100.0%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 49.0 4.48e-01 100.0% 96.7%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 46.0 4.37e-01 96.5% 95.7%
7odhL01 1.10.645.10 Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B 0.54 45.0 2.89e-01 89.6% 76.3%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 47.0 4.30e-01 100.0% 92.5%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 42.0 3.83e-01 92.2% 61.5%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 34.0 3.95e-01 74.8% 98.6%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 46.0 4.20e-01 99.1% 85.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 41.0 4.45e-01 93.0% 99.0%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.52 37.0 3.79e-01 85.2% 77.7%
6m20C01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 44.0 3.05e-01 100.0% 40.7%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.51 39.0 4.38e-01 100.0% 100.0%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 46.0 3.91e-01 100.0% 88.3%
3mzvA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.09e-01 88.7% 48.5%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.50 43.0 4.29e-01 94.8% 90.5%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4319295 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.67 36.0 3.78e-01 100.0% 56.2%
3866648 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.62 56.0 5.00e-01 99.1% 88.1%
3248680 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 49.0 4.99e-01 95.7% 90.0%
3192478 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 55.0 4.45e-01 100.0% 79.1%
3175356 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 43.0 3.78e-01 75.7% 98.9%
4226297 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.58 34.0 3.33e-01 93.9% 52.0%
3368549 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 51.0 4.18e-01 100.0% 70.5%
3593895 633.11.1.0 alpha bundles › Bromodomain-like › Nqo1C-terminal domain-like › Nqo1C-terminal domain-like 0.57 46.0 4.75e-01 97.4% 96.2%
3710592 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.57 39.0 4.17e-01 95.7% 84.2%
5030139 633.22.1.1 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › VKOR 0.57 45.0 4.29e-01 87.0% 97.1%
3164482 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 48.0 4.04e-01 94.8% 87.2%
4870707 4121.1.1.2 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like 0.56 46.0 3.70e-01 88.7% 94.4%
4192211 192.29.1.159 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ATG2_CAD 0.56 46.0 4.54e-01 99.1% 83.3%
4033422 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.18e-01 99.1% 89.9%
3291171 3813.1.1.2 alpha bundles › DUF416 › DUF416 › DUF416 › Imm5_like 0.56 40.0 3.60e-01 86.1% 51.2%
3676738 6158.1.1.0 alpha bundles › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region › Nucleoporin p58/p45 helical region 0.56 36.0 3.46e-01 100.0% 56.9%
4182983 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.55 44.0 4.58e-01 99.1% 88.2%
4026469 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 50.0 3.97e-01 100.0% 85.1%
2878134 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.55 44.0 4.17e-01 86.1% 76.4%
3239812 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.55 48.0 3.82e-01 93.9% 93.3%
3189902 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 47.0 3.89e-01 97.4% 88.2%
5075639 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.54 49.0 4.67e-01 99.1% 85.9%
3514684 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 43.0 4.31e-01 86.1% 96.5%
3255633 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 45.0 3.74e-01 100.0% 89.1%
3760677 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.52 40.0 2.70e-01 97.4% 21.9%
3819233 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.51 35.0 3.56e-01 72.2% 70.4%
5012671 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.58e-01 96.5% 76.5%
3238614 5001.1.1.69 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd 0.51 44.0 3.24e-01 96.5% 64.0%
3223128 109.4.1.63 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAP42 0.51 43.0 3.54e-01 95.7% 90.2%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 45.0 4.25e-01 94.8% 100.0%
4524127 7014.1.1.1 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.50 29.0 2.89e-01 94.8% 52.5%
D2 high residues 247-388
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04586.23 best Peptidase_S78 134.8 4.70e-39 96.5% 82.4%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1at3A00 3.20.16.10 Alpha Beta › Alpha-Beta Barrel › Serine Protease, Human Cytomegalovirus Protease; Chain A › Herpesvirus/Caudovirus protease domain 0.72 58.0 4.94e-01 90.1% 54.8%
1o6eA00 3.20.16.10 Alpha Beta › Alpha-Beta Barrel › Serine Protease, Human Cytomegalovirus Protease; Chain A › Herpesvirus/Caudovirus protease domain 0.67 57.0 4.85e-01 90.1% 61.3%
2ey4D00 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.66 36.0 4.61e-01 98.6% 96.0%
1x44A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 37.0 4.25e-01 99.3% 79.6%
1ywuA00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.61 35.0 3.74e-01 75.4% 62.4%
3l4jA04 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.60 35.0 4.07e-01 76.1% 79.4%
5yjlB01 3.30.460.30 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain 0.60 34.0 3.29e-01 71.1% 48.4%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.59 32.0 3.86e-01 73.9% 79.8%
2fm8B00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 40.0 4.20e-01 91.5% 77.6%
3cnrB00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.59 36.0 4.35e-01 74.6% 94.6%
8bxrA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 36.0 4.24e-01 99.3% 92.6%
2jllA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 36.0 4.21e-01 100.0% 92.6%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.57 34.0 3.95e-01 80.3% 84.5%
2wv3A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 37.0 4.25e-01 99.3% 92.0%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.56 35.0 4.01e-01 85.2% 86.0%
3kg5A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 37.0 4.20e-01 99.3% 92.2%
3lcyA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 35.0 4.11e-01 99.3% 92.8%
2wp3T00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 35.0 4.02e-01 99.3% 88.9%
1ry9A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.55 37.0 3.86e-01 91.5% 72.2%
1kafA00 3.90.1150.20 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription regulator MotA, C-terminal domain 0.54 28.0 3.09e-01 99.3% 59.3%
4fa8A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 37.0 4.18e-01 95.1% 94.2%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.54 31.0 3.76e-01 91.5% 86.0%
1ejfA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 37.0 4.20e-01 77.5% 90.9%
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 32.0 3.74e-01 84.5% 84.7%
4e9jA02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 28.0 3.60e-01 71.1% 100.0%
3gcfA01 3.90.380.10 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 0.52 39.0 3.20e-01 78.2% 73.6%
1n91A00 3.30.1200.10 Alpha Beta › 2-Layer Sandwich › Conserved Hypothetical Protein Mth637; Chain: A; › YggU-like 0.50 34.0 3.80e-01 70.4% 90.7%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3945940 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.95 90.0 8.97e-01 100.0% 95.2%
3980142 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.94 92.0 8.97e-01 100.0% 98.7%
4032431 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.93 86.0 8.35e-01 95.8% 90.3%
3954964 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.87 76.0 7.62e-01 91.5% 89.0%
5083161 50.1.1.3 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S78 0.87 83.0 8.24e-01 99.3% 98.6%
4995675 50.1.1.0 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin 0.80 75.0 7.10e-01 100.0% 95.2%
3585229 50.1.1.2 beta barrels › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Herpes virus serine proteinase, assemblin › Peptidase_S77 0.74 62.0 6.29e-01 88.7% 91.4%
3999603 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.61 33.0 3.79e-01 91.5% 72.0%
4280384 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.61 34.0 3.28e-01 71.1% 47.3%
184476 304.9.1.32 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Ret2_MD 0.60 32.0 3.82e-01 72.5% 76.3%
4993996 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.60 34.0 3.25e-01 71.1% 47.5%
3599334 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.60 32.0 3.70e-01 72.5% 71.0%
1291622 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.59 34.0 3.29e-01 71.8% 49.4%
4517135 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.59 35.0 3.33e-01 70.4% 47.4%
3238846 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 32.0 3.74e-01 91.5% 75.8%
4350351 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.58 34.0 3.26e-01 71.8% 48.8%
3701059 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 33.0 3.87e-01 92.3% 80.0%
4587782 304.41.1.1 a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.57 31.0 3.11e-01 70.4% 49.0%
3706789 3715.1.1.1 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.56 36.0 3.80e-01 84.5% 72.0%
3595281 3715.1.1.0 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e 0.56 35.0 3.84e-01 83.1% 74.2%
3921303 11.1.1.616 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig-like_KY 0.56 40.0 4.27e-01 100.0% 86.7%
3188905 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.55 37.0 3.41e-01 87.3% 52.8%
3620547 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.55 33.0 3.63e-01 94.4% 73.6%
3531801 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 35.0 4.10e-01 90.1% 94.7%
3490226 11.1.1.97 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.54 32.0 3.92e-01 95.1% 95.3%
5078176 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.53 28.0 3.59e-01 88.7% 92.0%
3249789 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 41.0 4.29e-01 97.9% 90.0%
5069267 318.1.1.1 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal_L6 0.53 30.0 3.92e-01 81.0% 100.0%
3478310 11.1.1.179 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 0.53 38.0 4.22e-01 99.3% 97.3%
3909864 11.1.1.99 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set 0.52 38.0 3.86e-01 99.3% 76.4%
5035989 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.52 30.0 3.63e-01 91.5% 86.7%
3742864 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.52 28.0 3.13e-01 70.4% 63.6%
4465073 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.52 33.0 3.81e-01 70.4% 87.5%
5939 327.11.2.3 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_6 0.52 29.0 3.66e-01 86.6% 96.2%
D3 high residues 401-447
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3u7iA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.80 56.0 3.58e-01 74.5% 16.1%
4f92B10 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.76 65.0 4.66e-01 100.0% 52.4%
2vixA02 1.10.150.630 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.71 62.0 5.07e-01 100.0% 60.7%
1vpwA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.68 49.0 4.64e-01 89.4% 64.9%
5dnyA03 6.10.10.50 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › Mre11, C-terminal domain-like 0.68 49.0 4.96e-01 78.7% 80.4%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 43.0 3.90e-01 74.5% 49.2%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.63 53.0 4.48e-01 100.0% 77.1%
6n8eA02 3.30.559.30 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Nonribosomal peptide synthetase, condensation domain 0.62 51.0 3.24e-01 97.9% 76.2%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.62 47.0 3.84e-01 83.0% 90.8%
2kwpA00 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.61 52.0 3.82e-01 100.0% 93.0%
2p6nA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 40.0 2.86e-01 72.3% 54.4%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 41.0 3.48e-01 74.5% 82.1%
3w3sA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 39.0 2.33e-01 72.3% 79.3%
1uxdA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 43.0 4.12e-01 91.5% 76.3%
1op1A00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.56 46.0 3.93e-01 95.7% 79.3%
2cr7A01 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.56 46.0 4.26e-01 95.7% 90.5%
5i41B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.55 43.0 3.85e-01 87.2% 76.1%
1xb2B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.54 42.0 3.96e-01 89.4% 71.7%
2x3fA02 3.30.1300.10 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › Pantoate-beta-alanine ligase, C-terminal domain 0.54 43.0 3.58e-01 100.0% 95.0%
3lupA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 2.84e-01 85.1% 85.2%
3g3oA00 3.20.100.30 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › VTC, catalytic tunnel domain 0.53 42.0 2.76e-01 100.0% 45.2%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 39.0 3.10e-01 91.5% 37.9%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 37.0 2.97e-01 89.4% 35.3%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 44.0 3.35e-01 97.9% 60.7%
2ymmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.51 39.0 3.56e-01 93.6% 83.6%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4946473 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.83 65.0 5.08e-01 83.0% 60.0%
4469296 3809.1.1.2 alpha bundles › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Caudo_TAP 0.80 55.0 4.77e-01 87.2% 48.6%
4007679 192.15.1.109 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Caudo_TAP 0.80 54.0 4.65e-01 85.1% 45.9%
3250375 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.76 52.0 4.46e-01 72.3% 45.3%
3952601 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.76 64.0 5.67e-01 97.9% 70.0%
3792733 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.73 54.0 3.43e-01 80.9% 39.1%
3718035 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.72 57.0 5.12e-01 89.4% 63.1%
4194552 3193.1.1.0 alpha arrays › HopAB effectors Pto-binding domain-related › HopAB effectors Pto-binding domain-related › HopAB effectors Pto-binding domain-related 0.69 56.0 4.64e-01 97.9% 50.6%
3844040 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.69 47.0 4.26e-01 72.3% 52.3%
3928911 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 48.0 4.31e-01 78.7% 57.1%
3638546 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.67 59.0 3.77e-01 100.0% 64.8%
3796175 192.15.1.99 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › PF31025 0.66 47.0 4.58e-01 76.6% 69.8%
3188839 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.65 56.0 3.55e-01 100.0% 61.2%
3636504 219.1.1.23 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › MINDY_DUB 0.64 46.0 2.87e-01 76.6% 13.0%
5046186 2006.1.4.50 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF3368 0.64 52.0 3.69e-01 95.7% 29.1%
4936706 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.64 51.0 3.24e-01 100.0% 17.5%
3260684 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.62 44.0 4.25e-01 83.0% 67.3%
4280714 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.61 49.0 4.77e-01 95.7% 85.5%
3277496 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 49.0 3.08e-01 100.0% 23.4%
4990527 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.58 50.0 3.79e-01 100.0% 50.8%
3766229 558.1.1.31 alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain › Synaphin 0.56 40.0 3.60e-01 76.6% 54.3%
3791357 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.54 37.0 2.53e-01 83.0% 20.6%
4846601 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.53 37.0 2.91e-01 80.9% 31.1%
3524358 2006.1.4.48 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DC_STAMP 0.52 42.0 3.43e-01 100.0% 64.8%
D4 medium residues 11-52
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1pzxA03 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.75 63.0 4.55e-01 97.6% 82.8%
2pmzB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.70 51.0 4.19e-01 78.6% 91.3%
2napA03 3.40.228.10 Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 0.68 50.0 3.15e-01 83.3% 73.1%
2hh2A00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.66 52.0 4.38e-01 90.5% 97.5%
1afsA00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.65 49.0 2.92e-01 83.3% 35.7%
1ciaA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.63 50.0 3.20e-01 88.1% 29.6%
1q0sA02 1.10.1020.10 Mainly Alpha › Orthogonal Bundle › Adenine-specific Methyltransferase; domain 2 › Adenine-specific Methyltransferase, Domain 2 0.62 46.0 3.59e-01 81.0% 66.3%
4hjhA03 3.40.120.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 › Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 0.61 46.0 3.43e-01 85.7% 90.4%
1neeA01 3.30.70.3150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 43.0 3.38e-01 81.0% 42.9%
3k17A01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.58 50.0 3.22e-01 100.0% 37.7%
2oycA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.58 44.0 3.27e-01 90.5% 98.4%
4yy8B01 3.30.710.10 Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A 0.54 38.0 3.16e-01 76.2% 76.9%
3c19A02 3.10.20.300 Alpha Beta › Roll › Ubiquitin-like (UB roll) › mk0293 like domain 0.53 40.0 3.52e-01 95.2% 69.2%
3svkA01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.50 42.0 2.81e-01 100.0% 61.5%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3972257 4325.1.1.0 mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.80 61.0 6.24e-01 83.3% 90.0%
3250206 65.1.1.0 beta sandwiches › Composite domain of metallo-dependent hydrolases › Composite domain of metallo-dependent hydrolases › Composite domain of metallo-dependent hydrolases 0.67 57.0 4.78e-01 100.0% 66.7%
3890848 221.1.1.9 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PI3K_rbd,PIK3CG_ABD 0.65 57.0 3.45e-01 100.0% 22.1%
4991239 101.1.2.1 alpha arrays › HTH › HTH › winged helix domain › HTH_1 0.62 50.0 3.83e-01 88.1% 52.6%
3714022 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.60 48.0 4.33e-01 90.5% 65.0%
3967464 275.1.1.0 a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase 0.58 48.0 4.29e-01 90.5% 73.3%
3796903 101.1.15.0 alpha arrays › HTH › HTH › HAT1, C-terminal domain 0.51 39.0 3.12e-01 83.3% 84.7%
D5 medium residues 63-107
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1b0yA00 4.10.490.10 Few Secondary Structures › Irregular › High-Potential Iron-Sulfur Protein; Chain A › High potential iron-sulphur protein 0.77 65.0 5.37e-01 100.0% 67.1%
3h31A00 4.10.490.10 Few Secondary Structures › Irregular › High-Potential Iron-Sulfur Protein; Chain A › High potential iron-sulphur protein 0.75 61.0 5.17e-01 100.0% 55.4%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3537468 376.1.6.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › IBR domain › IBR 0.57 37.0 3.17e-01 80.0% 40.0%
4249943 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.52 38.0 3.80e-01 82.2% 93.3%