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MH153804.1__AWN03636.1__PBI_JACE_15__00015

Bact-Vir

MH153804.1__AWN03636.1__PBI_JACE_15__00015

Identity

Accession:
MH153804 ↗
Kingdom:
phage

Quality

54.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 97-185_264-288
PDB
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.71 31.0 3.55e-01 93.9% 54.1%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 28.0 3.36e-01 96.5% 59.7%
1u7gA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.62 52.0 3.64e-01 93.0% 55.9%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 48.0 3.69e-01 82.5% 45.3%
2ddmB00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.60 46.0 3.47e-01 80.7% 77.1%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.58 40.0 4.09e-01 71.1% 89.2%
4mo7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 36.0 3.36e-01 100.0% 50.0%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.56 31.0 3.61e-01 97.4% 76.2%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.52 29.0 2.72e-01 94.7% 43.2%
6todA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 42.0 3.25e-01 93.9% 90.9%
1exaA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.50 44.0 3.53e-01 98.2% 79.2%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3500243 1008.1.1.74 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › CC_Cfap43 0.65 35.0 3.29e-01 93.0% 42.9%
4930117 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.63 49.0 4.04e-01 83.3% 88.1%
3961296 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.62 31.0 3.37e-01 93.9% 56.4%
4939828 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.61 28.0 2.02e-01 94.7% 14.6%
3225981 5067.1.1.5 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing 0.58 46.0 3.76e-01 87.7% 63.0%
3969836 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.58 45.0 3.70e-01 82.5% 91.4%
4972366 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.56 45.0 3.70e-01 84.2% 93.0%
3959831 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.55 39.0 3.61e-01 73.7% 83.3%
3950977 5058.1.1.9 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Colicin_V 0.54 39.0 3.52e-01 75.4% 89.0%
5016504 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 48.0 3.99e-01 100.0% 67.2%
5076969 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.92e-01 100.0% 71.8%
4181606 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.94e-01 100.0% 72.6%
3459019 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.52 35.0 3.57e-01 93.0% 69.6%
3600444 7064.1.1.0 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.51 44.0 4.11e-01 95.6% 95.2%
3649362 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 38.0 2.67e-01 77.2% 92.0%
3593427 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 30.0 2.72e-01 95.6% 42.6%
4057743 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 43.0 3.70e-01 96.5% 67.4%
D2 medium residues 186-263
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7qovB01 1.10.472.20 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Nitrile hydratase, beta subunit 0.61 43.0 3.89e-01 76.9% 52.8%
3vw4A01 1.10.340.50 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › 0.61 39.0 3.70e-01 93.6% 54.3%
3emlA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 44.0 3.04e-01 82.1% 94.8%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.58 34.0 3.56e-01 89.7% 62.5%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 38.0 3.38e-01 70.5% 47.3%
1qamA02 1.10.8.100 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain 0.56 41.0 4.13e-01 82.1% 76.9%
1jkwA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 38.0 2.94e-01 71.8% 31.8%
4o1jA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.55 46.0 3.58e-01 98.7% 71.1%
6bfnB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 45.0 3.45e-01 96.2% 71.3%
3lynB00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.54 39.0 3.48e-01 100.0% 50.0%
3lewA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 44.0 2.96e-01 91.0% 64.3%
1cqxA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 44.0 3.58e-01 89.7% 72.0%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 44.0 3.64e-01 89.7% 80.9%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 34.0 3.11e-01 100.0% 44.7%
2gf4A00 1.20.1270.110 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Uncharacterised protein family UPF0058 0.53 39.0 3.82e-01 79.5% 72.7%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.53 36.0 3.40e-01 85.9% 56.6%
3w0fA02 1.10.8.50 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.53 43.0 3.66e-01 92.3% 66.2%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 39.0 3.68e-01 80.8% 83.2%
3ihvA03 1.25.40.900 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 42.0 3.55e-01 91.0% 80.6%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.52 38.0 3.66e-01 80.8% 100.0%
3kttB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.51 37.0 2.64e-01 76.9% 56.1%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.51 45.0 3.38e-01 100.0% 77.1%
2gwlA00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.51 43.0 3.19e-01 92.3% 56.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 34.0 3.17e-01 70.5% 53.9%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4934144 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 44.0 4.43e-01 76.9% 85.0%
4946927 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.60 50.0 3.59e-01 91.0% 41.3%
5028668 206.1.3.3 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N 0.54 43.0 2.82e-01 88.5% 30.4%
3292 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.54 44.0 3.58e-01 89.7% 72.0%
4951139 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 46.0 4.24e-01 96.2% 95.0%
2394559 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.53 42.0 3.05e-01 94.9% 27.5%
4505595 605.6.1.0 alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like 0.53 34.0 3.22e-01 100.0% 51.0%
4306152 148.1.3.203 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF28760 0.53 42.0 3.43e-01 88.5% 77.4%
4391836 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.53 42.0 3.16e-01 91.0% 45.6%
4277031 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.53 30.0 3.20e-01 93.6% 63.1%
3483899 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.53 40.0 3.51e-01 84.6% 57.6%
4008972 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.51 40.0 3.50e-01 84.6% 96.7%
3722640 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 43.0 3.28e-01 100.0% 66.0%
5025867 3543.1.1.0 alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel 0.51 41.0 3.24e-01 93.6% 93.1%
4975282 545.1.2.0 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain 0.51 32.0 3.22e-01 89.7% 61.3%
3491320 526.1.1.1 alpha bundles › ERO1-like › ERO1-like › ERO1-like › ERO1 0.50 39.0 2.57e-01 87.2% 78.9%
4997148 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 42.0 3.24e-01 100.0% 68.6%
D3 medium residues 452-538_571-592
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.62 44.0 4.11e-01 74.3% 64.5%
1tzvA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.62 44.0 4.10e-01 75.2% 60.3%
2jo7A00 1.10.4170.10 Mainly Alpha › Orthogonal Bundle › Glycosylphosphatidylinositol-anchored merozoite surface protein › Glycosylphosphatidylinositol-anchored merozoite surface protein 0.61 47.0 3.69e-01 81.7% 43.3%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.60 40.0 3.34e-01 91.7% 39.7%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.58 43.0 4.13e-01 78.0% 88.1%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 41.0 3.97e-01 95.4% 65.6%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.57 42.0 3.85e-01 98.2% 57.4%
1px5A02 1.10.1410.20 Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › 2'-5'-oligoadenylate synthetase 1, domain 2 0.56 41.0 3.48e-01 76.1% 72.6%
2paqA00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.56 42.0 3.65e-01 81.7% 64.4%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.55 46.0 4.49e-01 89.9% 98.4%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 39.0 3.66e-01 100.0% 59.8%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.54 44.0 4.26e-01 89.9% 98.4%
5tk8A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.54 40.0 3.44e-01 79.8% 89.0%
1ed1A00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.54 40.0 3.94e-01 91.7% 73.7%
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.53 42.0 4.41e-01 99.1% 93.1%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 36.0 3.65e-01 85.3% 70.5%
3iqtA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.53 39.0 3.86e-01 93.6% 72.8%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.53 31.0 3.70e-01 100.0% 88.6%
2yvkA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.52 39.0 3.54e-01 78.9% 66.2%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 41.0 3.62e-01 84.4% 58.8%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 43.0 4.06e-01 89.9% 93.8%
6ncvA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 39.0 4.20e-01 77.1% 100.0%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 37.0 3.89e-01 73.4% 85.1%
1lm3B00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.52 39.0 4.03e-01 81.7% 100.0%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.52 41.0 3.91e-01 84.4% 84.3%
5tpmB00 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 44.0 4.05e-01 91.7% 75.2%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 38.0 3.84e-01 76.1% 84.9%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.52 42.0 4.17e-01 88.1% 90.4%
3godB02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.52 42.0 3.46e-01 89.0% 70.7%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 35.0 3.60e-01 83.5% 73.3%
2diwA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 37.0 3.46e-01 76.1% 88.7%
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.51 43.0 2.84e-01 93.6% 73.3%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.51 42.0 3.64e-01 87.2% 89.0%
3vkgA15 1.10.8.1220 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 36.0 3.84e-01 74.3% 100.0%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 44.0 4.41e-01 94.5% 95.4%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 44.0 3.73e-01 99.1% 57.5%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.50 43.0 3.69e-01 94.5% 68.0%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1721599 613.1.1.1 alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c 0.64 40.0 3.79e-01 100.0% 53.1%
5012015 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 38.0 3.27e-01 100.0% 37.7%
3693930 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 40.0 3.57e-01 71.6% 72.3%
5043157 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.57 48.0 4.71e-01 89.9% 93.0%
3214008 613.1.1.1 alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c 0.57 40.0 3.27e-01 100.0% 40.5%
3989179 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.56 44.0 3.53e-01 84.4% 64.4%
4966819 3236.1.1.2 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › SBF 0.56 41.0 2.94e-01 75.2% 29.7%
5053890 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.54 46.0 4.57e-01 92.7% 96.5%
3808186 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.54 47.0 4.32e-01 96.3% 86.9%
5006519 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 42.0 3.44e-01 88.1% 69.5%
3600676 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.53 38.0 3.86e-01 76.1% 78.2%
3934701 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 43.0 3.47e-01 89.0% 98.6%
3922520 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.52 45.0 4.07e-01 92.7% 77.9%
3440427 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 39.0 3.14e-01 82.6% 45.8%
3728798 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 42.0 3.63e-01 90.8% 87.4%
3377135 604.6.1.2 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › ANTH 0.50 40.0 3.61e-01 85.3% 87.3%
5042223 601.30.1.1 alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.50 39.0 3.68e-01 86.2% 80.7%
D4 medium residues 670-781
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.74 42.0 4.39e-01 71.4% 59.0%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 42.0 3.74e-01 90.2% 41.4%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.69 51.0 5.46e-01 78.6% 89.7%
6pnjL00 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.65 50.0 4.47e-01 80.4% 68.6%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 43.0 4.26e-01 82.1% 67.8%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 38.0 3.73e-01 87.5% 57.3%
6rv2A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 49.0 3.78e-01 93.8% 65.7%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 41.0 3.71e-01 75.9% 90.5%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.55 39.0 3.88e-01 83.9% 69.2%
1i36A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 40.0 4.20e-01 75.9% 100.0%
6nsjA00 1.25.40.600 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter 0.54 42.0 3.56e-01 82.1% 73.1%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.54 43.0 3.89e-01 90.2% 61.9%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 39.0 4.17e-01 86.6% 86.0%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.54 38.0 3.62e-01 92.0% 62.1%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.52 43.0 3.78e-01 88.4% 76.5%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 36.0 3.51e-01 86.6% 64.8%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 35.0 3.59e-01 89.3% 70.9%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.50 40.0 4.12e-01 96.4% 90.5%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4993526 101.11.1.13 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › EMC6_arch 0.73 49.0 5.50e-01 71.4% 88.6%
3894123 148.1.3.56 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Arv1 0.64 46.0 3.84e-01 78.6% 43.7%
3241376 3890.1.1.3 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › ZYG-11_interact 0.63 49.0 3.99e-01 80.4% 71.5%
4246272 3921.1.1.0 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D 0.63 47.0 3.96e-01 77.7% 100.0%
3932947 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.62 43.0 3.84e-01 70.5% 57.4%
3958387 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.62 49.0 4.32e-01 85.7% 64.7%
5044882 140.1.1.7 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.61 41.0 3.32e-01 85.7% 35.7%
3179188 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.59 51.0 4.91e-01 96.4% 80.8%
5038783 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.58 48.0 3.52e-01 91.1% 52.2%
5004570 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.56 37.0 4.30e-01 99.1% 100.0%
3221100 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 42.0 4.07e-01 84.8% 71.2%
5014127 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.54 49.0 3.69e-01 100.0% 58.9%
3833759 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.54 45.0 3.59e-01 90.2% 60.1%
3386367 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.54 39.0 3.73e-01 76.8% 71.1%
3902140 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 39.0 4.17e-01 99.1% 88.4%
3373782 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.52 38.0 3.79e-01 75.9% 73.9%
4446522 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.51 40.0 3.76e-01 83.9% 70.0%
4091420 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.50 43.0 3.96e-01 92.9% 83.4%
D5 medium residues 861-950
PDB
D6 medium residues 1194-1246
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 68.0 6.06e-01 96.2% 60.3%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.85 77.0 6.63e-01 98.1% 65.0%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.83 66.0 4.82e-01 94.3% 33.6%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.83 61.0 3.92e-01 84.9% 18.6%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.82 55.0 4.24e-01 90.6% 33.0%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.82 69.0 6.21e-01 98.1% 67.6%
5lbmA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.81 74.0 6.30e-01 100.0% 63.9%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 57.0 5.12e-01 81.1% 54.1%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.80 69.0 4.87e-01 98.1% 42.7%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.79 69.0 6.03e-01 98.1% 64.2%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 63.0 5.13e-01 96.2% 47.4%
3tuiA00 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.78 62.0 4.07e-01 92.5% 21.3%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.78 70.0 6.02e-01 100.0% 67.5%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 63.0 5.17e-01 92.5% 52.0%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.75 57.0 4.36e-01 100.0% 36.8%
3pdiA02 3.40.50.12380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal 0.75 52.0 3.29e-01 83.0% 14.3%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.69 50.0 3.35e-01 84.9% 19.4%
4xeaA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.68 46.0 3.13e-01 71.7% 49.0%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.65 50.0 3.89e-01 90.6% 36.7%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 45.0 3.50e-01 79.2% 34.3%
2qbyB01 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 42.0 3.46e-01 77.4% 37.3%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3600712 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.89 76.0 6.36e-01 100.0% 57.6%
3731364 3922.1.1.137 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › HisKA 0.86 66.0 6.11e-01 88.7% 66.2%
3248284 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.84 67.0 5.27e-01 94.3% 43.8%
4962781 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.84 68.0 5.97e-01 92.5% 61.3%
3607111 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 70.0 4.66e-01 94.3% 25.3%
2075294 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.76 63.0 5.14e-01 92.5% 50.5%
4042986 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.66 59.0 4.79e-01 100.0% 59.0%