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MH179474.1__AWH14685.1__X__00053

Bact-Vir

MH179474.1__AWH14685.1__X__00053

Identity

Accession:
MH179474 ↗
Kingdom:
phage

Quality

77.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 515-570
PDB
Domain cluster: representative
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.97 88.0 7.87e-01 100.0% 72.6%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.95 85.0 5.40e-01 100.0% 22.5%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.95 74.0 8.01e-01 87.5% 95.8%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.94 76.0 6.87e-01 89.3% 66.2%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.93 82.0 5.71e-01 98.2% 33.3%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.93 76.0 4.98e-01 91.1% 24.4%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.92 85.0 5.83e-01 100.0% 32.4%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.92 77.0 7.46e-01 91.1% 80.6%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.91 76.0 6.67e-01 100.0% 63.6%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.91 84.0 6.06e-01 100.0% 39.4%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.90 64.0 6.84e-01 73.2% 100.0%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.90 79.0 6.51e-01 100.0% 55.8%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.90 67.0 7.09e-01 82.1% 86.3%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.90 84.0 6.08e-01 100.0% 40.9%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 74.0 7.55e-01 87.5% 90.7%
2a26B01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.89 65.0 7.32e-01 83.9% 97.7%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.88 77.0 6.85e-01 98.2% 68.4%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.88 79.0 6.09e-01 100.0% 47.4%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.88 65.0 5.39e-01 83.9% 47.3%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.87 70.0 5.29e-01 85.7% 38.7%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.87 69.0 4.97e-01 91.1% 32.0%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.85 75.0 7.08e-01 98.2% 80.6%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.85 78.0 6.12e-01 100.0% 73.4%
5o5jT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.84 75.0 6.54e-01 100.0% 71.8%
3p42A02 6.10.250.2280 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.84 63.0 5.83e-01 87.5% 64.3%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.83 65.0 6.01e-01 91.1% 66.2%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.83 73.0 7.02e-01 98.2% 85.7%
2rklF00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.83 70.0 7.28e-01 94.6% 100.0%
6umqA01 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.83 72.0 5.51e-01 92.9% 45.2%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 72.0 6.77e-01 98.2% 86.8%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 73.0 6.69e-01 100.0% 81.9%
1luwA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.81 70.0 6.71e-01 94.6% 85.9%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.81 71.0 6.71e-01 98.2% 85.3%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.81 72.0 6.26e-01 100.0% 87.1%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.81 72.0 5.19e-01 100.0% 40.1%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.81 71.0 5.55e-01 100.0% 47.1%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.80 66.0 5.09e-01 89.3% 42.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.79 67.0 5.66e-01 98.2% 68.7%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 65.0 5.38e-01 92.9% 51.5%
2lf0A01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.77 66.0 6.47e-01 98.2% 88.3%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.76 66.0 4.86e-01 94.6% 44.7%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.76 63.0 4.37e-01 94.6% 28.1%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 65.0 5.99e-01 100.0% 77.3%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.75 58.0 5.95e-01 85.7% 94.1%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.75 65.0 4.06e-01 100.0% 75.6%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.74 65.0 4.79e-01 100.0% 38.8%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.74 60.0 5.90e-01 94.6% 83.9%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 61.0 5.93e-01 100.0% 95.3%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.72 53.0 4.81e-01 100.0% 57.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 60.0 5.62e-01 98.2% 76.1%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.70 62.0 5.19e-01 100.0% 57.1%
2d5wA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.70 49.0 3.25e-01 75.0% 20.3%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 49.0 4.50e-01 96.4% 55.1%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 60.0 5.35e-01 100.0% 69.9%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 58.0 5.70e-01 98.2% 93.4%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 58.0 3.99e-01 100.0% 26.2%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.68 53.0 5.33e-01 92.9% 86.2%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.68 57.0 5.02e-01 98.2% 63.2%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.67 46.0 4.61e-01 92.9% 71.2%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 50.0 4.72e-01 87.5% 68.1%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 49.0 4.71e-01 83.9% 73.8%
3hpcX00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.64 55.0 4.07e-01 100.0% 38.1%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.62 50.0 4.65e-01 100.0% 71.8%
2x6hA03 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.56 48.0 3.34e-01 98.2% 38.5%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4300890 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.98 80.0 7.54e-01 85.7% 73.8%
4438372 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.98 74.0 4.42e-01 78.6% 14.4%
3204772 192.1.1.31 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › Cep57_MT_bd 0.96 90.0 7.22e-01 100.0% 56.0%
3705830 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.96 89.0 6.02e-01 98.2% 31.4%
4017817 3922.1.1.229 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Cep57_MT_bd 0.95 89.0 6.41e-01 100.0% 40.0%
4838801 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.94 78.0 7.37e-01 91.1% 75.4%
4317258 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.93 74.0 6.98e-01 83.9% 72.3%
3484742 3922.1.1.197 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp 0.92 87.0 7.37e-01 100.0% 65.9%
3703494 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.92 81.0 6.24e-01 92.9% 47.3%
3595002 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.92 87.0 6.92e-01 100.0% 56.0%
4106385 3291.1.1.89 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › CHD5 0.92 79.0 6.40e-01 92.9% 57.0%
3480252 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.91 74.0 6.60e-01 85.7% 64.0%
4936792 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.91 86.0 5.72e-01 100.0% 30.3%
4338795 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.91 85.0 5.84e-01 100.0% 32.9%
3693025 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.91 74.0 7.28e-01 89.3% 81.7%
3926919 3710.1.1.0 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain 0.91 78.0 7.66e-01 92.9% 85.0%
3507551 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.91 85.0 6.91e-01 100.0% 58.9%
3448091 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.90 84.0 6.46e-01 100.0% 55.3%
5025381 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.90 85.0 5.05e-01 100.0% 17.0%
3186698 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.90 83.0 7.22e-01 98.2% 68.8%
4175684 3291.1.1.232 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Paralemmin 0.89 80.0 5.92e-01 100.0% 41.5%
3776620 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.89 83.0 5.71e-01 100.0% 33.7%
4049273 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.89 77.0 7.11e-01 92.9% 74.3%
1106555 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.89 82.0 7.69e-01 100.0% 95.5%
3215342 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.89 77.0 6.36e-01 100.0% 55.8%
4411992 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.88 77.0 6.12e-01 94.6% 54.3%
4128596 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.88 75.0 7.09e-01 92.9% 78.5%
3881288 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.88 81.0 6.35e-01 100.0% 50.9%
3593272 375.1.9.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase 0.87 78.0 5.67e-01 94.6% 41.5%
3237324 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.87 74.0 7.22e-01 100.0% 83.3%
3744786 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.87 74.0 6.09e-01 91.1% 53.7%
4060910 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.87 80.0 6.36e-01 100.0% 64.8%
4476610 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.87 76.0 6.08e-01 92.9% 54.0%
3836427 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.87 75.0 6.12e-01 100.0% 53.0%
3638319 192.7.1.56 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › CHD5 0.87 80.0 6.45e-01 100.0% 61.0%
3491418 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.86 77.0 6.99e-01 100.0% 84.0%
4225217 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.86 78.0 6.18e-01 100.0% 52.7%
3646439 192.8.1.263 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF7615 0.86 78.0 6.72e-01 100.0% 65.9%
4479100 192.29.1.244 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CHD5 0.86 79.0 6.27e-01 100.0% 59.0%
4670545 3711.1.1.61 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › CHD5 0.85 78.0 6.57e-01 100.0% 67.8%
4381724 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.85 77.0 6.34e-01 100.0% 57.9%
4039421 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.85 79.0 6.35e-01 100.0% 59.0%
4363885 3922.1.1.139 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › CHD5 0.85 78.0 6.20e-01 100.0% 58.1%
3784740 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.83 76.0 6.80e-01 100.0% 74.7%
3793090 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.83 76.0 4.43e-01 100.0% 14.2%
4507133 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.82 75.0 6.23e-01 100.0% 61.1%
3266118 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.82 72.0 5.51e-01 98.2% 44.0%
3440913 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.81 74.0 5.48e-01 100.0% 41.5%
3564399 3755.3.1.282 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 0.81 61.0 4.84e-01 100.0% 40.0%
5079778 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.81 72.0 4.20e-01 100.0% 27.5%
5047384 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 67.0 6.45e-01 98.2% 86.2%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.77 66.0 5.67e-01 100.0% 77.9%
3754265 603.1.1.187 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DNA_repr_REX1B 0.77 66.0 5.60e-01 94.6% 58.9%
3884763 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 68.0 5.02e-01 100.0% 38.6%
3594486 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 64.0 5.08e-01 100.0% 45.8%
3194153 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.76 65.0 5.52e-01 98.2% 58.9%
3595108 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.76 66.0 5.60e-01 96.4% 61.1%
437078 3713.1.1.1 alpha bundles › Small terminase central domain › Small terminase central domain › Small terminase central domain › DNA_Packaging 0.76 65.0 5.63e-01 100.0% 63.7%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.73 61.0 4.17e-01 100.0% 24.7%
4784164 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 61.0 5.77e-01 100.0% 80.0%
4798159 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 61.0 5.60e-01 100.0% 73.7%
D2 medium residues 11-76
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08273.18 best Zn_Ribbon_Prim 36.5 6.60e-09 39.4% 59.5%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u3eM02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 41.0 4.16e-01 83.3% 86.8%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2876 101.1.14.2 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › I-HmuI_NUMOD-like 0.54 41.0 4.13e-01 83.3% 85.5%
4414927 101.1.14.3 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › NUMOD1 0.54 41.0 4.05e-01 81.8% 88.4%
D3 medium residues 77-168
PDB
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1nr4C00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.61 28.0 3.24e-01 87.0% 59.1%
2bhgA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.60 41.0 4.17e-01 84.8% 71.7%
3g12B00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.59 32.0 3.01e-01 91.3% 40.7%
5cbeE00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.58 28.0 3.35e-01 88.0% 65.6%
1icwB00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.57 29.0 3.42e-01 92.4% 68.2%
2re3A02 2.30.270.10 Mainly Beta › Roll › duf1285 protein fold › duf1285 protein 0.56 32.0 3.57e-01 78.3% 72.9%
1xezA04 2.100.10.30 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Jacalin-like lectin domain 0.52 37.0 3.24e-01 97.8% 49.6%
3tzgA00 2.40.160.150 Mainly Beta › Beta Barrel › Porin › 0.51 39.0 2.88e-01 80.4% 35.6%
4emhA00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.51 26.0 3.10e-01 81.5% 73.3%
3qcmA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.50 38.0 2.75e-01 81.5% 62.6%
1qftB00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.50 44.0 3.60e-01 95.7% 72.8%
4ybvA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.50 38.0 3.47e-01 80.4% 93.4%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4159881 220.1.1.197 beta barrels › PH domain-like › PH domain-like › PH domain-like › PF28623 0.61 36.0 3.63e-01 81.5% 56.8%
3510862 5.1.4.173 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR75_2nd 0.59 42.0 2.82e-01 75.0% 94.1%
3515806 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 32.0 2.79e-01 72.8% 37.0%
4031476 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.54 43.0 4.16e-01 84.8% 84.5%
2879361 76.1.1.0 beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I 0.54 38.0 3.15e-01 98.9% 42.7%
5043802 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 34.0 3.22e-01 81.5% 52.2%
3208578 76.1.1.7 beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I › DUF7600 0.52 38.0 3.43e-01 98.9% 56.0%
3794500 4.1.1.287 beta barrels › SH3 › SH3 › SH3 › DUF5641 0.52 38.0 3.01e-01 76.1% 63.8%
3936953 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 36.0 2.52e-01 71.7% 74.6%
3675560 252.1.1.0 a+b two layers › DNA-binding domain › Methyl-CpG-binding domain, MBD › Methyl-CpG-binding domain, MBD 0.51 41.0 3.97e-01 89.1% 84.6%
D4 medium residues 169-294
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13362.13 best Toprim_3 41.7 1.80e-10 78.6% 97.9%
D5 medium residues 677-770
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rfyB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.72 36.0 3.73e-01 77.7% 51.1%
2v6zM00 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.71 44.0 4.92e-01 78.7% 78.7%
4d81A02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 47.0 4.72e-01 92.6% 78.7%
1ng6A01 1.10.1510.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Protein Yqey; Chain: A; domain1 › Uncharacterised protein YqeY/AIM41, N-terminal domain 0.62 45.0 4.65e-01 88.3% 80.2%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.62 49.0 4.95e-01 87.2% 88.4%
3umbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 42.0 4.47e-01 70.2% 83.5%
2k3qA00 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.61 44.0 4.11e-01 87.2% 61.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.61 47.0 4.07e-01 84.0% 56.3%
1eo0A00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.58 38.0 4.07e-01 88.3% 80.5%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.58 41.0 4.05e-01 78.7% 68.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 49.0 4.37e-01 93.6% 75.4%
1vgpA02 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.58 40.0 3.92e-01 79.8% 65.4%
2lfwA01 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.58 43.0 3.80e-01 88.3% 53.2%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.57 43.0 4.18e-01 87.2% 70.4%
1e94E03 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.57 45.0 4.39e-01 87.2% 75.5%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.57 45.0 3.86e-01 86.2% 66.7%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.57 44.0 4.13e-01 83.0% 68.4%
3kv0A01 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.56 45.0 3.72e-01 87.2% 70.6%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 38.0 4.15e-01 70.2% 84.6%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 44.0 4.26e-01 86.2% 81.5%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 41.0 3.84e-01 83.0% 79.7%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 45.0 3.96e-01 93.6% 68.5%
2gbbB00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.53 44.0 3.80e-01 92.6% 63.9%
3b8mC02 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 36.0 3.55e-01 70.2% 84.6%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 40.0 3.76e-01 78.7% 83.6%
3lopA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 40.0 3.17e-01 85.1% 92.4%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.50 45.0 4.45e-01 97.9% 93.8%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.50 39.0 3.90e-01 86.2% 85.4%
3egcA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 38.0 3.46e-01 81.9% 82.0%
2wmoA01 1.25.40.410 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A 0.50 38.0 3.38e-01 80.9% 62.7%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4304398 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.79 55.0 5.55e-01 86.2% 71.6%
4940788 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.78 67.0 6.83e-01 91.5% 98.9%
3610493 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.76 51.0 5.50e-01 83.0% 80.0%
4976513 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.76 56.0 6.20e-01 81.9% 96.0%
1628548 148.1.3.17 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › MCM_lid 0.75 62.0 6.12e-01 87.2% 82.8%
4014858 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.72 65.0 6.14e-01 97.9% 82.7%
4998716 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.71 47.0 4.91e-01 85.1% 74.1%
4011290 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.68 46.0 4.87e-01 87.2% 77.6%
4023259 148.1.3.212 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_13 0.68 59.0 5.14e-01 94.7% 79.3%
3676159 148.1.3.46 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Cdc6-ORC-like_ATPase_lid 0.68 45.0 4.53e-01 92.6% 67.4%
3402127 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 48.0 4.96e-01 87.2% 78.9%
5078781 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.67 54.0 5.55e-01 88.3% 91.1%
5044340 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 51.0 5.31e-01 81.9% 96.5%
4959600 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 51.0 5.42e-01 84.0% 90.6%
4211419 103.2.1.2 alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.64 50.0 4.71e-01 85.1% 76.5%
3488934 6157.1.1.1 alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP 0.63 52.0 4.66e-01 88.3% 90.8%
3711195 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 50.0 4.80e-01 87.2% 90.0%
3812000 7023.1.1.3 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT_2 0.62 43.0 3.97e-01 72.3% 55.2%
3917311 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.62 51.0 4.51e-01 90.4% 79.9%
3173999 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 47.0 4.62e-01 90.4% 78.0%
3976441 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.60 46.0 4.23e-01 81.9% 64.0%
3609099 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.60 45.0 4.61e-01 78.7% 95.6%
4089545 1037.1.1.1 alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT 0.59 46.0 3.38e-01 84.0% 70.0%
5001331 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.58 44.0 4.13e-01 83.0% 67.0%
3253011 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.58 43.0 2.62e-01 80.9% 64.0%
3216411 4009.1.1.23 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › C_tripleX 0.57 41.0 4.31e-01 76.6% 100.0%
3261835 148.1.3.6 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Vps4_C,AAA_lid_3 0.57 42.0 4.04e-01 93.6% 67.3%
4823728 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 45.0 4.36e-01 86.2% 80.8%
3182665 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.56 43.0 4.37e-01 83.0% 89.5%
3454679 148.1.3.19 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.56 39.0 4.42e-01 85.1% 100.0%
3471420 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.55 44.0 4.33e-01 87.2% 88.0%
3820970 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.54 43.0 3.85e-01 86.2% 80.0%
3216129 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.54 43.0 3.94e-01 86.2% 72.0%
3626813 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.54 42.0 3.39e-01 86.2% 65.0%
None 0.53 42.0 3.02e-01 88.3% 64.9%
3308688 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.53 39.0 4.23e-01 85.1% 100.0%
3360363 633.6.1.2 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX 0.52 44.0 3.45e-01 92.6% 75.5%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.51 45.0 4.25e-01 93.6% 89.1%
D6 medium residues 772-836
PDB