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MH248138.1__AWY08511.1__Alexandra_254__00252

Bact-Vir

MH248138.1__AWY08511.1__Alexandra_254__00252

Identity

Accession:
MH248138 ↗
Kingdom:
phage

Quality

46.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 17-108
PDB
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ezjA01 1.10.287.320 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Viral phosphoprotein oligmorisation site domain 0.71 37.0 4.43e-01 97.8% 75.8%
7vevA01 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.66 46.0 3.36e-01 72.8% 76.2%
4oevA03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.60 42.0 3.15e-01 72.8% 76.8%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.58 42.0 3.90e-01 76.1% 75.4%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 42.0 3.73e-01 76.1% 80.2%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 39.0 4.19e-01 80.4% 89.2%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.56 47.0 4.11e-01 90.2% 73.5%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.54 39.0 3.42e-01 78.3% 96.1%
4o7oA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.54 39.0 2.97e-01 78.3% 72.0%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 42.0 3.71e-01 92.4% 66.4%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.51 42.0 4.09e-01 97.8% 82.4%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.51 46.0 4.29e-01 100.0% 99.1%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.50 40.0 3.20e-01 89.1% 93.5%
4ye6A01 1.10.8.1290 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1 0.50 36.0 3.55e-01 97.8% 69.2%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3514956 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.63 54.0 4.27e-01 94.6% 79.0%
3824153 611.7.1.11 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 0.60 50.0 4.56e-01 94.6% 85.4%
3979252 601.46.1.1 alpha bundles › Four-helical up-and-down bundle › Regulatory CZB domain of diguanylate cyclase YdeH › Regulatory CZB domain of diguanylate cyclase YdeH › CZB 0.59 43.0 4.06e-01 76.1% 90.0%
4957124 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.58 47.0 3.30e-01 89.1% 51.7%
3211066 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.58 45.0 3.22e-01 82.6% 76.2%
3216492 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.55 41.0 3.90e-01 77.2% 83.8%
3831756 2003.1.2.16 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3,NAD_binding_8 0.55 48.0 3.48e-01 97.8% 82.2%
3249525 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.55 41.0 3.56e-01 79.3% 72.4%
3605151 1189.1.1.3 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP 0.54 39.0 3.12e-01 77.2% 83.4%
5030859 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 40.0 3.63e-01 76.1% 75.0%
3587178 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.54 45.0 3.48e-01 95.7% 91.1%
3945003 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 39.0 3.35e-01 77.2% 62.0%
4945223 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 45.0 3.10e-01 94.6% 52.3%
4008098 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.52 38.0 3.59e-01 79.3% 79.2%
3642864 207.1.1.95 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.52 41.0 3.01e-01 89.1% 55.4%
D2 high residues 169-283
PDB
D3 high residues 314-412
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dbzA01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.62 52.0 4.22e-01 90.9% 71.7%
2mqdA00 3.30.1460.60 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.58 42.0 3.99e-01 75.8% 91.6%
5f7uA02 2.60.40.1760 Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) 0.57 46.0 3.56e-01 88.9% 98.2%
3cwxA00 3.40.1420.20 Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Pathogenicity island component CagD 0.56 46.0 4.30e-01 100.0% 71.2%
1yzbA01 3.90.70.40 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.55 39.0 3.63e-01 74.7% 58.1%
3a7sA00 3.40.532.10 Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase 0.55 41.0 3.24e-01 78.8% 82.8%
3vp7A00 1.10.418.40 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Autophagy protein 6/Beclin 1 0.53 47.0 4.01e-01 99.0% 95.8%
2a4vA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 41.0 3.70e-01 86.9% 76.4%
2z99A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 36.0 3.81e-01 100.0% 82.8%
5koxA02 3.30.70.2450 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 31.0 3.33e-01 83.8% 69.8%
1t6sA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 37.0 3.91e-01 74.7% 96.5%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4936603 304.120.1.6 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.67 40.0 4.90e-01 83.8% 92.3%
3925754 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.60 34.0 3.09e-01 79.8% 40.7%
4122483 4018.1.1.1 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › FBPase 0.60 47.0 4.10e-01 85.9% 86.5%
3462595 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.57 37.0 3.93e-01 84.8% 73.3%
3284638 4205.1.1.3 a+b two layers › SMI1/KNR4-like › SMI1/KNR4-like › SMI1/KNR4-like › SMI1_KNR4 0.54 47.0 4.17e-01 98.0% 100.0%
3173084 331.1.1.13 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › CPSF73-100_C 0.53 38.0 4.07e-01 78.8% 87.1%
3988118 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.52 35.0 3.76e-01 100.0% 82.4%
4849322 5.1.3.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.50 37.0 3.03e-01 75.8% 70.8%
D4 medium residues 468-554
PDB
D5 medium residues 604-699
PDB