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MH375597.1__AXF53640.1__X__00024
Bact-VirMH375597.1__AXF53640.1__X__00024
Identity
- Accession:
- MH375597 ↗
- Kingdom:
- phage
Quality
88.9
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Aliceevansviridae›
Moineauvirus›
Streptococcus_phage_123
TaxID: 2268615
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-53
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF28149.1 best | AcrIIA6 | 99.4 | 3.20e-28 | 100.0% | 29.6% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2h92A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 58.0 | 3.77e-01 | 79.2% | 20.8% |
| 1ez0B01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.76 | 53.0 | 3.26e-01 | 77.4% | 12.5% |
| 4v19K02 | 1.10.10.250 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain | 0.75 | 55.0 | 4.89e-01 | 79.2% | 56.0% |
| 1t90A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.72 | 51.0 | 3.16e-01 | 77.4% | 13.9% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.72 | 59.0 | 4.98e-01 | 90.6% | 56.3% |
| 3d5lA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.70 | 47.0 | 4.81e-01 | 79.2% | 73.1% |
| 2ymmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.70 | 56.0 | 5.14e-01 | 92.5% | 79.5% |
| 6pmiF01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.67 | 52.0 | 4.61e-01 | 86.8% | 58.7% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 45.0 | 4.47e-01 | 79.2% | 67.9% |
| 4o8sA02 | 1.20.58.1790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain | 0.65 | 47.0 | 3.83e-01 | 79.2% | 39.3% |
| 7t7kA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.63 | 44.0 | 3.43e-01 | 75.5% | 89.8% |
| 3g36B00 | 1.20.890.10 | Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 0.62 | 46.0 | 4.67e-01 | 90.6% | 86.3% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 43.0 | 3.56e-01 | 73.6% | 44.4% |
| 2xzmO02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.62 | 43.0 | 3.95e-01 | 73.6% | 60.0% |
| 1hlvA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.62 | 44.0 | 4.31e-01 | 81.1% | 68.3% |
| 3k3wB03 | 1.10.1400.10 | Mainly Alpha › Orthogonal Bundle › Penicillin amidase (Acylase) alpha subunit, N-terminal domain › Aminohydrolase, alpha-helical knob region | 0.60 | 52.0 | 3.77e-01 | 98.1% | 87.4% |
| 1o9gA02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 41.0 | 4.55e-01 | 75.5% | 88.4% |
| 4ixjA01 | 3.30.1300.80 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.59 | 43.0 | 3.89e-01 | 83.0% | 55.8% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 46.0 | 4.54e-01 | 84.9% | 82.5% |
| 1ufhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.59 | 43.0 | 3.27e-01 | 86.8% | 31.0% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 45.0 | 4.48e-01 | 84.9% | 85.2% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.58 | 45.0 | 4.31e-01 | 90.6% | 78.1% |
| 3um7A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 41.0 | 3.30e-01 | 75.5% | 68.9% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 42.0 | 3.87e-01 | 77.4% | 75.0% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 44.0 | 3.80e-01 | 86.8% | 74.7% |
| 2f8lA01 | 1.10.150.470 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 47.0 | 4.19e-01 | 96.2% | 76.5% |
| 5ywwA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.56 | 42.0 | 3.36e-01 | 84.9% | 70.4% |
| 3l6gA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.53 | 42.0 | 3.12e-01 | 90.6% | 91.3% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 42.0 | 3.85e-01 | 84.9% | 69.7% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5064861 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.80 | 64.0 | 4.04e-01 | 86.8% | 18.8% |
| 3967283 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.74 | 64.0 | 5.31e-01 | 98.1% | 67.4% |
| 3588902 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.70 | 53.0 | 3.86e-01 | 88.7% | 30.7% |
| 3712152 | 190.1.1.0 ↗ | alpha arrays › HMG-box-like › HMG-box › HMG-box | 0.67 | 48.0 | 4.75e-01 | 77.4% | 74.5% |
| 3788441 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.66 | 52.0 | 4.67e-01 | 86.8% | 61.3% |
| 3451862 | 10.13.1.0 ↗ | beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A | 0.62 | 43.0 | 2.84e-01 | 73.6% | 20.4% |
| 3600023 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.61 | 47.0 | 3.35e-01 | 84.9% | 52.7% |
| 3289263 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.59 | 44.0 | 3.95e-01 | 77.4% | 77.1% |
| 3673805 | 148.1.3.285 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Cyclin_C | 0.59 | 48.0 | 4.27e-01 | 98.1% | 75.3% |
| 3262581 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.58 | 44.0 | 3.06e-01 | 81.1% | 44.2% |
| 4020387 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.57 | 50.0 | 2.98e-01 | 100.0% | 60.2% |
| 4432304 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.56 | 38.0 | 3.92e-01 | 81.1% | 76.0% |
| 4558763 | 223.2.1.20 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_1 | 0.55 | 48.0 | 3.62e-01 | 100.0% | 47.4% |
| 3419469 | 3444.2.1.0 ↗ | alpha arrays › DP domain › XPC-binding domain and DDI helical domain › XPC-binding domain | 0.54 | 40.0 | 4.02e-01 | 86.8% | 76.4% |
| 3497466 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.53 | 43.0 | 3.58e-01 | 88.7% | 54.4% |
| 3829877 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 42.0 | 2.83e-01 | 86.8% | 29.1% |
| 3588172 | 10.12.1.0 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix | 0.51 | 46.0 | 3.30e-01 | 100.0% | 56.7% |
| 4228771 | 506.2.1.0 ↗ | beta meanders › Colicin E3 ribonuclease domain-like › UvrB interaction domain › UvrB interaction domain | 0.50 | 45.0 | 3.18e-01 | 100.0% | 76.9% |
D2
medium
residues 54-125
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF28149.1 best | AcrIIA6 | 133.5 | 1.10e-38 | 94.4% | 38.0% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3gd6A01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.57 | 49.0 | 3.99e-01 | 100.0% | 66.9% |
| 2olsA02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.56 | 43.0 | 3.57e-01 | 87.5% | 91.6% |
| 3mqqB00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.56 | 37.0 | 3.19e-01 | 97.2% | 41.5% |
| 3nqzA02 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 33.0 | 3.14e-01 | 100.0% | 52.4% |
| 1uzxA00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.52 | 37.0 | 2.98e-01 | 100.0% | 38.6% |
| 3ugfB02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.51 | 44.0 | 3.40e-01 | 100.0% | 44.6% |
| 5iu1B00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.51 | 35.0 | 3.08e-01 | 91.7% | 46.4% |
| 2r5rA00 | 3.10.270.10 | Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; | 0.50 | 38.0 | 2.71e-01 | 84.7% | 87.4% |
| 1x6cA00 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.50 | 43.0 | 3.74e-01 | 98.6% | 61.9% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2387861 | 330.18.1.1 ↗ | a+b two layers › dsRBD-like › Anti-CRISPR protein AcrIIA6 › Anti-CRISPR protein AcrIIA6 › AcrIIA6 | 0.91 | 85.0 | 7.71e-01 | 100.0% | 77.4% |
| 4242897 | 5.1.4.61 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PAN2_N | 0.59 | 51.0 | 3.26e-01 | 98.6% | 21.4% |
| None | — | 0.58 | 41.0 | 3.33e-01 | 93.1% | 37.9% | |
| 4015718 | 65.1.1.0 ↗ | beta sandwiches › Composite domain of metallo-dependent hydrolases › Composite domain of metallo-dependent hydrolases › Composite domain of metallo-dependent hydrolases | 0.58 | 37.0 | 4.02e-01 | 93.1% | 78.3% |
| 3719969 | 5.1.3.160 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_KLHDC2_KLHL20_DRC7, Beta-prop_ATRN-LZTR1 | 0.58 | 49.0 | 3.21e-01 | 97.2% | 31.3% |
| 3786814 | 5.1.2.20 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › BMT | 0.57 | 48.0 | 2.99e-01 | 95.8% | 24.3% |
| 3272662 | 12.3.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich | 0.56 | 38.0 | 2.59e-01 | 70.8% | 74.7% |
| 3858796 | 5.1.3.147 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Beta-prop_ATRN-LZTR1 | 0.55 | 46.0 | 3.03e-01 | 97.2% | 24.8% |
| 3497892 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.55 | 47.0 | 2.89e-01 | 98.6% | 43.4% |
| 3204035 | 1.1.17.4 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 | 0.54 | 42.0 | 2.73e-01 | 84.7% | 63.5% |
| 3537881 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.53 | 46.0 | 3.60e-01 | 100.0% | 78.2% |
| 4433752 | 5.1.3.35 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neuraminidase | 0.53 | 45.0 | 3.09e-01 | 98.6% | 41.1% |
| 4013926 | 9.4.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › D-aminopeptidase, middle and C-terminal domains › D-aminopeptidase, middle and C-terminal domains › PF26335 | 0.52 | 35.0 | 2.89e-01 | 100.0% | 36.4% |
| 5035416 | 212.1.1.0 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like | 0.52 | 39.0 | 3.50e-01 | 81.9% | 100.0% |
| 3463416 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.52 | 38.0 | 2.90e-01 | 80.6% | 60.0% |
| 4466001 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.51 | 41.0 | 3.39e-01 | 91.7% | 47.4% |
| 4026119 | 11.1.4.16 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › EMC7_beta-sandw | 0.51 | 34.0 | 2.98e-01 | 97.2% | 43.5% |
| 3241453 | 2484.1.1.233 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1280 | 0.51 | 41.0 | 2.74e-01 | 90.3% | 50.5% |
| 5042375 | 2.26.1.1 ↗ | beta barrels › OB-fold › Arcadin-1 › Arcadin-1 › Arcadin_1 | 0.51 | 41.0 | 4.06e-01 | 91.7% | 100.0% |
| 3752543 | 7.1.1.17 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain › PDZ, PDZ_6 | 0.51 | 43.0 | 3.84e-01 | 100.0% | 71.8% |
| 3719862 | 5.1.3.116 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_KLHDC2_KLHL20_DRC7 | 0.51 | 42.0 | 2.81e-01 | 98.6% | 29.1% |
| 4015457 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.50 | 34.0 | 2.79e-01 | 72.2% | 41.3% |
| 3968213 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 36.0 | 2.39e-01 | 77.8% | 21.9% |