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MH598799.1__AXH71712.1__P025_gp38__00038
Bact-VirMH598799.1__AXH71712.1__P025_gp38__00038
Identity
- Accession:
- MH598799 ↗
- Kingdom:
- phage
Quality
80.4
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Autographivirales›
Thoosavirus›
Pelagibacter_phage_HTVC025P
TaxID: 2259657
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 82-193
Domain cluster:
representative
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jt6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.69 | 49.0 | 4.62e-01 | 74.1% | 65.0% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.68 | 35.0 | 3.29e-01 | 100.0% | 40.6% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.68 | 55.0 | 4.84e-01 | 87.5% | 64.2% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.66 | 55.0 | 5.56e-01 | 90.2% | 96.4% |
| 5d1rB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 59.0 | 4.67e-01 | 99.1% | 59.7% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.65 | 57.0 | 5.66e-01 | 95.5% | 96.5% |
| 5iduA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.63 | 44.0 | 4.32e-01 | 71.4% | 66.7% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.62 | 44.0 | 3.95e-01 | 73.2% | 92.3% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.62 | 44.0 | 4.65e-01 | 89.3% | 82.2% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 50.0 | 4.24e-01 | 87.5% | 66.3% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.61 | 40.0 | 3.76e-01 | 94.6% | 53.7% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 54.0 | 4.68e-01 | 99.1% | 97.2% |
| 1td6A01 | 1.20.1480.10 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 | 0.61 | 38.0 | 4.01e-01 | 79.5% | 68.6% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 34.0 | 3.20e-01 | 100.0% | 44.0% |
| 2qtqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 54.0 | 4.49e-01 | 99.1% | 68.5% |
| 2wglA00 | 1.10.4190.10 | Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF | 0.60 | 50.0 | 4.08e-01 | 91.1% | 80.9% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.59 | 42.0 | 3.84e-01 | 73.2% | 98.0% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 47.0 | 4.72e-01 | 85.7% | 99.1% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 44.0 | 4.01e-01 | 80.4% | 95.3% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 42.0 | 4.01e-01 | 77.7% | 75.6% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 38.0 | 4.24e-01 | 77.7% | 89.4% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.57 | 38.0 | 3.97e-01 | 81.2% | 75.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 43.0 | 4.46e-01 | 80.4% | 100.0% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 38.0 | 3.79e-01 | 80.4% | 65.5% |
| 1j77A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.56 | 42.0 | 3.48e-01 | 78.6% | 62.8% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.56 | 37.0 | 3.85e-01 | 73.2% | 73.5% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 50.0 | 4.18e-01 | 100.0% | 65.1% |
| 1ylmA00 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.55 | 40.0 | 3.69e-01 | 79.5% | 59.2% |
| 3s0xA01 | 1.20.120.1220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 37.0 | 3.45e-01 | 70.5% | 86.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 44.0 | 4.58e-01 | 99.1% | 99.0% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.53 | 43.0 | 4.43e-01 | 88.4% | 99.1% |
| 1kplA00 | 1.10.3080.10 | Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel | 0.53 | 47.0 | 3.21e-01 | 100.0% | 68.6% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 44.0 | 4.56e-01 | 98.2% | 99.1% |
| 3jq0A00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 47.0 | 3.11e-01 | 100.0% | 77.6% |
| 1z72A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 36.0 | 2.98e-01 | 72.3% | 67.1% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 41.0 | 3.99e-01 | 98.2% | 75.0% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 40.0 | 3.86e-01 | 84.8% | 76.1% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 39.0 | 4.23e-01 | 80.4% | 100.0% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3386308 | 604.3.1.46 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF28048 | 0.75 | 53.0 | 5.85e-01 | 98.2% | 91.1% |
| 3920864 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.75 | 59.0 | 5.39e-01 | 85.7% | 64.1% |
| 3259377 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.74 | 57.0 | 6.11e-01 | 80.4% | 100.0% |
| 3589723 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 59.0 | 5.76e-01 | 92.0% | 95.2% |
| 2722819 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.68 | 56.0 | 4.42e-01 | 89.3% | 83.5% |
| 4249597 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 49.0 | 5.05e-01 | 75.0% | 85.7% |
| 5035274 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.67 | 40.0 | 3.89e-01 | 85.7% | 54.2% |
| 3251975 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.67 | 42.0 | 5.11e-01 | 92.0% | 100.0% |
| 3464388 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.65 | 42.0 | 4.24e-01 | 81.2% | 63.5% |
| 3722363 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.65 | 57.0 | 5.03e-01 | 94.6% | 87.5% |
| 4577554 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 45.0 | 4.89e-01 | 77.7% | 88.4% |
| 4001046 | 109.4.1.342 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SBF2 | 0.62 | 55.0 | 4.07e-01 | 97.3% | 53.4% |
| 3614715 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.60 | 45.0 | 3.72e-01 | 79.5% | 72.7% |
| 3587197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 45.0 | 4.09e-01 | 78.6% | 72.0% |
| 3665138 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.60 | 48.0 | 4.92e-01 | 84.8% | 90.5% |
| 4061713 | 5069.1.3.10 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I | 0.60 | 42.0 | 4.11e-01 | 73.2% | 74.4% |
| 3969464 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 48.0 | 4.35e-01 | 87.5% | 92.9% |
| 3466285 | 6155.1.1.6 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 | 0.59 | 44.0 | 3.67e-01 | 84.8% | 45.8% |
| 5079046 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.59 | 44.0 | 4.13e-01 | 76.8% | 65.7% |
| 3609141 | 633.15.1.1 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › BCDHK_Adom3 | 0.59 | 41.0 | 3.53e-01 | 73.2% | 88.6% |
| 3360919 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 41.0 | 3.75e-01 | 72.3% | 85.4% |
| 3528012 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.58 | 42.0 | 3.38e-01 | 75.9% | 65.3% |
| 3203554 | 7516.1.1.51 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_21 | 0.57 | 46.0 | 3.09e-01 | 86.6% | 92.4% |
| 3929825 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.57 | 38.0 | 3.79e-01 | 75.0% | 64.2% |
| 3914266 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.57 | 40.0 | 3.56e-01 | 73.2% | 64.4% |
| 3211052 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.56 | 40.0 | 2.95e-01 | 73.2% | 43.9% |
| 3258502 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.56 | 42.0 | 3.38e-01 | 76.8% | 77.6% |
| 4033315 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.56 | 49.0 | 4.31e-01 | 100.0% | 68.6% |
| 3350068 | 633.22.1.1 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › VKOR | 0.55 | 45.0 | 3.93e-01 | 90.2% | 58.2% |
| 3390092 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 39.0 | 3.74e-01 | 76.8% | 63.1% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 44.0 | 4.06e-01 | 85.7% | 76.9% |
| 3189692 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.54 | 40.0 | 3.19e-01 | 77.7% | 77.0% |
| 3570028 | 904.1.1.0 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain | 0.54 | 38.0 | 3.26e-01 | 72.3% | 76.6% |
| 3860629 | 192.29.1.45 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › ELO | 0.54 | 42.0 | 3.27e-01 | 82.1% | 69.6% |
| 4065014 | 9001.1.1.2 ↗ | alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › ELO | 0.54 | 42.0 | 3.20e-01 | 82.1% | 64.2% |
| 4030651 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 40.0 | 3.34e-01 | 80.4% | 61.0% |
| 3916865 | 109.4.1.117 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › STAG,SCD | 0.54 | 47.0 | 3.65e-01 | 99.1% | 71.2% |
| 4993210 | 3755.3.1.635 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PHA_synth_III_E | 0.53 | 39.0 | 3.37e-01 | 77.7% | 60.5% |
| 3730019 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.53 | 48.0 | 3.83e-01 | 100.0% | 100.0% |
| 5045324 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.53 | 43.0 | 3.56e-01 | 87.5% | 53.5% |
| 5019219 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.52 | 37.0 | 2.81e-01 | 75.0% | 57.3% |
| 4032631 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.52 | 43.0 | 3.61e-01 | 92.9% | 91.7% |
| 3955097 | 304.28.2.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB TolC docking domain | 0.52 | 38.0 | 3.46e-01 | 75.9% | 77.9% |
| 3298699 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.51 | 40.0 | 3.34e-01 | 83.9% | 70.0% |
D2
medium
residues 221-324
Domain cluster:
rep: MT375524.1__QLF88228.1__Gjalp_gp36__00035__D195-298
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.80 | 56.0 | 5.47e-01 | 72.1% | 100.0% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.76 | 45.0 | 5.34e-01 | 73.1% | 84.9% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.71 | 50.0 | 4.75e-01 | 72.1% | 72.7% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.70 | 52.0 | 4.70e-01 | 76.0% | 81.5% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 47.0 | 4.85e-01 | 71.2% | 94.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.69 | 47.0 | 4.69e-01 | 71.2% | 99.1% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 47.0 | 4.91e-01 | 74.0% | 88.7% |
| 1vw4L01 | 3.90.1030.10 | Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 | 0.59 | 33.0 | 3.06e-01 | 71.2% | 40.7% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 49.0 | 4.91e-01 | 90.4% | 91.7% |
| 2jifA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 47.0 | 4.52e-01 | 88.5% | 89.0% |
| 7craA02 | 1.20.58.1480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 33.0 | 3.50e-01 | 89.4% | 65.2% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 43.0 | 4.40e-01 | 96.2% | 83.0% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 45.0 | 4.53e-01 | 83.7% | 100.0% |
| 3spcA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 41.0 | 3.80e-01 | 82.7% | 60.6% |
| 4qfvC02 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.55 | 33.0 | 4.01e-01 | 82.7% | 95.4% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 40.0 | 4.35e-01 | 76.0% | 100.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.55 | 42.0 | 4.65e-01 | 80.8% | 98.8% |
| 3mzvA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 44.0 | 3.27e-01 | 91.3% | 82.2% |
| 4qiqA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 47.0 | 3.10e-01 | 95.2% | 93.6% |
| 2h7oA02 | 1.20.58.1230 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rac1-binding domain, C-terminal subdomain | 0.52 | 43.0 | 3.80e-01 | 87.5% | 84.4% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 39.0 | 3.41e-01 | 77.9% | 62.0% |
| 1s7zA01 | 1.20.120.780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr | 0.51 | 35.0 | 3.55e-01 | 81.7% | 72.3% |
| 2lpnA00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.50 | 36.0 | 3.60e-01 | 73.1% | 74.3% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5062016 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.73 | 50.0 | 5.15e-01 | 70.2% | 100.0% |
| 3825046 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 50.0 | 4.48e-01 | 75.0% | 75.2% |
| 4883406 | 622.4.1.1 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 | 0.69 | 50.0 | 4.79e-01 | 74.0% | 92.2% |
| 1758759 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.68 | 43.0 | 3.28e-01 | 79.8% | 29.3% |
| 4930612 | 4009.1.1.4 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › DUF3243 | 0.67 | 39.0 | 4.35e-01 | 76.9% | 73.8% |
| 3254975 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.66 | 49.0 | 4.79e-01 | 78.8% | 93.9% |
| 3704359 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 50.0 | 4.15e-01 | 82.7% | 61.7% |
| 3504302 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 43.0 | 4.44e-01 | 71.2% | 100.0% |
| 3723690 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.63 | 43.0 | 4.05e-01 | 70.2% | 85.6% |
| 4459896 | 622.4.1.1 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 | 0.61 | 50.0 | 4.83e-01 | 85.6% | 94.7% |
| 3713159 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 49.0 | 4.73e-01 | 86.5% | 90.0% |
| 3491111 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 45.0 | 4.63e-01 | 78.8% | 100.0% |
| 3534087 | 604.1.1.67 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 | 0.60 | 49.0 | 4.99e-01 | 86.5% | 100.0% |
| 3580347 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 48.0 | 4.79e-01 | 85.6% | 99.0% |
| 3817383 | 109.4.1.401 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NRDE-2 | 0.59 | 41.0 | 3.98e-01 | 71.2% | 66.1% |
| 3938862 | 604.1.1.98 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 | 0.59 | 47.0 | 4.62e-01 | 85.6% | 93.6% |
| 4983442 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 47.0 | 4.88e-01 | 86.5% | 100.0% |
| 3295481 | 109.4.1.401 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NRDE-2 | 0.58 | 48.0 | 2.85e-01 | 90.4% | 86.1% |
| 3797417 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.57 | 44.0 | 3.78e-01 | 81.7% | 53.9% |
| 3701816 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 47.0 | 4.50e-01 | 89.4% | 97.5% |
| 4025698 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 41.0 | 3.38e-01 | 81.7% | 47.4% |
| 3591989 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.52 | 45.0 | 3.44e-01 | 94.2% | 80.9% |
| 4977678 | 192.1.1.50 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › EMC3_TMCO1 | 0.51 | 42.0 | 3.64e-01 | 90.4% | 100.0% |
| 3635930 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.50 | 43.0 | 3.77e-01 | 93.3% | 68.4% |
D3
medium
residues 325-371
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2uyyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.71 | 57.0 | 4.42e-01 | 100.0% | 41.5% |
| 3e3vA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.68 | 57.0 | 5.60e-01 | 100.0% | 96.2% |
| 2fq3A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 57.0 | 4.74e-01 | 100.0% | 71.8% |
| 1xfiA02 | 1.20.1700.10 | Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like | 0.66 | 44.0 | 3.59e-01 | 70.2% | 43.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 46.0 | 3.45e-01 | 74.5% | 31.4% |
| 3d5lA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.65 | 52.0 | 5.32e-01 | 95.7% | 100.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 54.0 | 4.12e-01 | 100.0% | 84.6% |
| 4mhcA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 47.0 | 3.11e-01 | 87.2% | 21.2% |
| 1hu3A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 51.0 | 3.40e-01 | 93.6% | 28.4% |
| 2dk8A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 52.0 | 4.75e-01 | 95.7% | 75.4% |
| 8amqA02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.62 | 50.0 | 3.05e-01 | 100.0% | 68.5% |
| 4eqqA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 49.0 | 4.97e-01 | 97.9% | 100.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.61 | 43.0 | 3.57e-01 | 89.4% | 40.7% |
| 3d5lB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 49.0 | 4.04e-01 | 100.0% | 47.1% |
| 1blwC00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 44.0 | 3.16e-01 | 80.9% | 26.2% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 48.0 | 3.52e-01 | 97.9% | 46.3% |
| 6jlzA01 | 1.20.120.1070 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain | 0.60 | 50.0 | 3.98e-01 | 100.0% | 65.7% |
| 3qldA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.59 | 48.0 | 3.54e-01 | 100.0% | 36.8% |
| 3owaA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.59 | 48.0 | 3.56e-01 | 95.7% | 53.6% |
| 2a6cA00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.59 | 44.0 | 3.76e-01 | 95.7% | 50.0% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 3.81e-01 | 100.0% | 81.7% |
| 2is6A04 | 1.10.486.10 | Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 | 0.58 | 46.0 | 3.24e-01 | 91.5% | 30.4% |
| 3iwaA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 47.0 | 3.10e-01 | 100.0% | 29.5% |
| 3c2gA02 | 1.10.10.1630 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sys-1 C-terminal domain-like | 0.57 | 44.0 | 4.01e-01 | 91.5% | 73.5% |
| 5dukB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 44.0 | 4.14e-01 | 100.0% | 76.1% |
| 3ppuB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 43.0 | 3.55e-01 | 100.0% | 66.4% |
| 3dfgA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 44.0 | 4.40e-01 | 95.7% | 95.8% |
| 1gtxA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.55 | 45.0 | 2.80e-01 | 91.5% | 15.6% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.55 | 38.0 | 3.61e-01 | 74.5% | 94.8% |
| 8d8lN01 | 1.10.287.1480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 40.0 | 3.43e-01 | 87.2% | 50.0% |
| 2zxiA04 | 1.10.150.570 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › GidA associated domain, C-terminal subdomain | 0.54 | 37.0 | 3.68e-01 | 97.9% | 69.8% |
| 5aj3N01 | 1.10.287.1480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 40.0 | 3.35e-01 | 89.4% | 47.3% |
| 4nj8A01 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.53 | 40.0 | 3.90e-01 | 91.5% | 86.0% |
| 2e7xA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 44.0 | 4.28e-01 | 100.0% | 94.2% |
| 3akjA02 | 1.10.1070.20 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › | 0.51 | 41.0 | 2.84e-01 | 100.0% | 51.7% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3286921 | 129.1.1.16 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 | 0.76 | 65.0 | 4.83e-01 | 100.0% | 40.0% |
| 3712805 | 129.1.1.16 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 | 0.73 | 60.0 | 4.27e-01 | 100.0% | 32.5% |
| 3810387 | 563.1.1.0 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.69 | 55.0 | 4.58e-01 | 97.9% | 93.7% |
| 3365177 | 109.4.1.353 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MOR2-PAG1_N | 0.69 | 56.0 | 3.63e-01 | 95.7% | 44.6% |
| 3708811 | 195.1.1.3 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NSUN5_N | 0.69 | 54.0 | 4.13e-01 | 95.7% | 36.0% |
| 1068636 | 101.35.1.5 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 | 0.68 | 57.0 | 5.60e-01 | 100.0% | 96.2% |
| 3249557 | 195.1.1.3 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NSUN5_N | 0.68 | 53.0 | 4.03e-01 | 97.9% | 33.6% |
| 4440593 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.67 | 56.0 | 5.54e-01 | 95.7% | 98.0% |
| 3936021 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.67 | 42.0 | 2.71e-01 | 70.2% | 14.3% |
| 1551861 | 529.1.1.1 ↗ | few secondary structure elements › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › Anaphylotoxins (complement system) › ANATO | 0.67 | 55.0 | 4.88e-01 | 100.0% | 63.5% |
| 4620055 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.66 | 56.0 | 3.61e-01 | 100.0% | 77.9% |
| 5055634 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.66 | 56.0 | 4.78e-01 | 97.9% | 76.2% |
| 1169399 | 101.35.1.2 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Lipoprotein_Ltp | 0.66 | 55.0 | 5.36e-01 | 100.0% | 96.2% |
| 3189168 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.65 | 54.0 | 5.13e-01 | 100.0% | 93.3% |
| None | — | 0.64 | 52.0 | 2.93e-01 | 100.0% | 6.8% | |
| 3731622 | 109.1.1.26 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_N_3 | 0.64 | 54.0 | 3.39e-01 | 93.6% | 41.9% |
| 3981539 | 532.2.1.1 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ | 0.64 | 54.0 | 4.63e-01 | 97.9% | 63.7% |
| 3921064 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.64 | 52.0 | 2.98e-01 | 100.0% | 8.4% |
| 4575061 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.64 | 51.0 | 5.10e-01 | 97.9% | 94.0% |
| 3958129 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.63 | 44.0 | 3.65e-01 | 74.5% | 72.9% |
| 4089208 | 101.1.1.25 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF433 | 0.63 | 50.0 | 4.52e-01 | 89.4% | 98.5% |
| 4650006 | 101.1.2.39 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpA | 0.63 | 50.0 | 4.61e-01 | 100.0% | 67.1% |
| 4536531 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.63 | 49.0 | 4.94e-01 | 97.9% | 94.0% |
| 4362510 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 50.0 | 2.73e-01 | 89.4% | 7.2% |
| 3611035 | 1189.1.1.3 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP | 0.62 | 48.0 | 3.20e-01 | 93.6% | 56.4% |
| 1688094 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 49.0 | 4.58e-01 | 100.0% | 71.9% |
| 4342260 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.61 | 47.0 | 4.78e-01 | 95.7% | 100.0% |
| 4495474 | 101.39.1.1 ↗ | alpha arrays › HTH › Replication protein RepB C-terminal domain › Replication protein RepB C-terminal domain › RepB_C | 0.61 | 52.0 | 4.65e-01 | 100.0% | 75.7% |
| 3219554 | 103.12.1.0 ↗ | alpha arrays › RuvA-C › ANTAR domain › ANTAR domain | 0.60 | 40.0 | 4.03e-01 | 70.2% | 74.0% |
| 3505605 | 101.1.15.1 ↗ | alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS | 0.60 | 51.0 | 4.21e-01 | 100.0% | 67.8% |
| 3193555 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.59 | 39.0 | 4.03e-01 | 70.2% | 71.1% |
| 5029539 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 48.0 | 4.23e-01 | 100.0% | 58.7% |
| 4197338 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.59 | 46.0 | 4.57e-01 | 97.9% | 94.0% |
| 3404575 | 101.1.15.1 ↗ | alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS | 0.59 | 51.0 | 4.12e-01 | 97.9% | 75.6% |
| 3519172 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 45.0 | 4.48e-01 | 89.4% | 84.0% |
| 4500830 | 101.35.1.1 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH2 | 0.58 | 44.0 | 4.41e-01 | 97.9% | 92.0% |
| 4887991 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.56 | 46.0 | 3.71e-01 | 100.0% | 46.7% |
| 3688545 | 109.1.1.36 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_N | 0.55 | 47.0 | 2.99e-01 | 100.0% | 22.7% |
| 3193848 | 109.4.1.1276 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAT, HEAT_ATR | 0.55 | 46.0 | 2.95e-01 | 100.0% | 19.2% |
| 3258187 | 558.1.1.1 ↗ | alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain › LisH | 0.54 | 40.0 | 3.95e-01 | 89.4% | 78.2% |
| 4045132 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.53 | 39.0 | 3.06e-01 | 80.9% | 41.8% |
| 3838803 | 4168.1.1.0 ↗ | alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain | 0.51 | 44.0 | 3.99e-01 | 100.0% | 76.9% |
| 3517168 | 219.1.1.16 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 | 0.50 | 42.0 | 2.75e-01 | 100.0% | 20.9% |
D4
medium
residues 430-548
Domain cluster:
representative
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.71 | 54.0 | 5.17e-01 | 79.0% | 70.4% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 45.0 | 4.83e-01 | 75.6% | 76.0% |
| 1xfiA02 | 1.20.1700.10 | Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like | 0.66 | 41.0 | 4.67e-01 | 83.2% | 83.3% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 44.0 | 4.52e-01 | 84.0% | 70.9% |
| 1u84A00 | 1.10.340.20 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain | 0.64 | 34.0 | 4.11e-01 | 95.8% | 76.5% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 46.0 | 4.40e-01 | 84.0% | 64.9% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 36.0 | 4.49e-01 | 85.7% | 89.3% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.63 | 47.0 | 4.79e-01 | 91.6% | 79.3% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 42.0 | 4.18e-01 | 84.9% | 71.8% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.57 | 46.0 | 3.96e-01 | 85.7% | 89.1% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.57 | 40.0 | 3.48e-01 | 73.9% | 47.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 47.0 | 4.79e-01 | 94.1% | 91.5% |
| 1z72A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.57 | 50.0 | 4.10e-01 | 95.8% | 75.0% |
| 2pm6A00 | 1.25.40.1030 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 41.0 | 2.95e-01 | 76.5% | 38.0% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.55 | 35.0 | 3.95e-01 | 95.8% | 83.3% |
| 1uaaA04 | 1.10.486.10 | Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 | 0.55 | 37.0 | 3.35e-01 | 93.3% | 48.1% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 39.0 | 3.90e-01 | 84.9% | 71.1% |
| 1xeqB00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.55 | 35.0 | 4.00e-01 | 94.1% | 88.2% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.55 | 40.0 | 3.61e-01 | 79.0% | 54.2% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.54 | 44.0 | 4.39e-01 | 87.4% | 85.2% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 43.0 | 3.35e-01 | 86.6% | 96.1% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 45.0 | 3.53e-01 | 95.8% | 75.0% |
| 3iq2A00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.51 | 40.0 | 3.96e-01 | 95.8% | 79.7% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 40.0 | 3.66e-01 | 82.4% | 81.9% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 44.0 | 4.10e-01 | 97.5% | 80.8% |
| 7p5hB03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.50 | 34.0 | 3.78e-01 | 87.4% | 91.0% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3739839 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.70 | 57.0 | 5.93e-01 | 86.6% | 100.0% |
| 4016062 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.69 | 45.0 | 5.18e-01 | 84.9% | 92.9% |
| 3787527 | 142.3.1.1 ↗ | alpha complex topology › Sigma2 domain-like › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Sld7_C | 0.68 | 47.0 | 5.42e-01 | 73.9% | 98.8% |
| 3474500 | 632.7.1.25 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › PF27508 | 0.66 | 45.0 | 5.23e-01 | 78.2% | 97.6% |
| 3928795 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.66 | 46.0 | 5.09e-01 | 85.7% | 91.6% |
| 3862606 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 44.0 | 4.30e-01 | 84.0% | 64.6% |
| 3435812 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.61 | 50.0 | 4.99e-01 | 89.9% | 92.8% |
| 3601925 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.61 | 39.0 | 4.36e-01 | 83.2% | 84.4% |
| 3200574 | 601.1.2.81 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Serinc | 0.60 | 44.0 | 4.43e-01 | 84.9% | 76.7% |
| 3588296 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.59 | 43.0 | 4.16e-01 | 84.9% | 67.7% |
| 3680924 | 5054.1.1.61 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO | 0.56 | 50.0 | 3.90e-01 | 99.2% | 73.6% |
| 3613860 | 601.1.2.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17 | 0.56 | 44.0 | 4.18e-01 | 92.4% | 71.4% |
| 3626992 | 632.8.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C | 0.55 | 40.0 | 4.29e-01 | 88.2% | 86.7% |
| 3654270 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.55 | 44.0 | 4.25e-01 | 85.7% | 95.6% |
| 3530312 | 2485.1.1.120 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Strabismus | 0.54 | 41.0 | 4.08e-01 | 82.4% | 93.8% |
| 3441419 | 5051.1.1.6 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans | 0.54 | 41.0 | 2.80e-01 | 79.0% | 80.8% |
| 2526325 | 601.7.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN | 0.51 | 40.0 | 3.44e-01 | 86.6% | 52.4% |
| 3804223 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.51 | 42.0 | 3.84e-01 | 94.1% | 66.7% |