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MH744418.1__AYD81482.1__SEA_JUSTBECAUSE_327__00313

Bact-Vir

MH744418.1__AYD81482.1__SEA_JUSTBECAUSE_327__00313

Identity

Accession:
MH744418 ↗
Kingdom:
phage

Quality

88.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-98
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 54.0 4.49e-01 72.3% 49.7%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.73 60.0 5.42e-01 87.2% 85.6%
3nyjA00 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.73 53.0 4.21e-01 75.5% 48.6%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.73 53.0 4.33e-01 75.5% 65.9%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.72 48.0 4.32e-01 100.0% 49.2%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 48.0 4.35e-01 100.0% 50.0%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.70 59.0 5.29e-01 90.4% 83.6%
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 45.0 4.08e-01 100.0% 48.1%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 53.0 4.97e-01 84.0% 100.0%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 56.0 4.02e-01 89.4% 75.1%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 49.0 4.79e-01 75.5% 82.5%
7e84A02 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.67 53.0 4.66e-01 85.1% 93.5%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.67 45.0 5.08e-01 100.0% 93.0%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 48.0 3.83e-01 75.5% 68.9%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 53.0 4.83e-01 87.2% 98.4%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 45.0 3.39e-01 83.0% 30.8%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.65 56.0 5.02e-01 93.6% 88.4%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.65 45.0 4.66e-01 100.0% 76.7%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.65 52.0 4.76e-01 88.3% 97.6%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.64 52.0 4.32e-01 100.0% 50.9%
3n3dB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.63 55.0 3.87e-01 98.9% 55.3%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 51.0 4.46e-01 91.5% 78.4%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 56.0 5.14e-01 98.9% 97.5%
2yv9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 50.0 4.42e-01 86.2% 78.4%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 48.0 4.47e-01 81.9% 96.5%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.61 47.0 4.46e-01 84.0% 89.7%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 44.0 4.59e-01 74.5% 89.5%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 42.0 4.28e-01 71.3% 100.0%
3oqlC00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.61 42.0 3.16e-01 71.3% 60.3%
6g94A00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.60 48.0 3.94e-01 85.1% 89.5%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 51.0 4.74e-01 90.4% 85.3%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 50.0 3.57e-01 100.0% 30.9%
4g10A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 46.0 4.07e-01 81.9% 80.9%
3f1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.60 48.0 4.13e-01 87.2% 89.9%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 46.0 3.46e-01 84.0% 32.4%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.59 45.0 4.23e-01 81.9% 99.1%
3pvtA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 45.0 3.15e-01 83.0% 25.0%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.59 43.0 3.90e-01 77.7% 59.1%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 51.0 4.60e-01 98.9% 96.3%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 49.0 4.61e-01 90.4% 87.8%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 3.99e-01 74.5% 77.8%
6srbA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 47.0 4.48e-01 86.2% 88.1%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.58 49.0 4.15e-01 96.8% 80.1%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 49.0 4.60e-01 90.4% 87.5%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.57 42.0 3.81e-01 77.7% 85.5%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 48.0 4.53e-01 90.4% 86.0%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 48.0 4.49e-01 90.4% 85.8%
4aybA07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.56 40.0 3.73e-01 74.5% 86.7%
3ppuB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 47.0 4.41e-01 90.4% 88.5%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.56 45.0 4.78e-01 96.8% 100.0%
3cllA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.56 46.0 3.44e-01 90.4% 87.1%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 50.0 3.52e-01 100.0% 39.9%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 45.0 4.28e-01 89.4% 84.8%
1za0A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.54 44.0 3.29e-01 89.4% 47.5%
4bujE03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.54 41.0 3.11e-01 79.8% 68.2%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 42.0 4.11e-01 86.2% 87.7%
3wecA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 44.0 2.93e-01 92.6% 92.0%
1g2nA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 43.0 3.22e-01 90.4% 62.6%
2b7mA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.52 44.0 2.86e-01 97.9% 28.5%
4cfsA02 1.10.210.20 Mainly Alpha › Orthogonal Bundle › Uteroglobin › 0.51 33.0 3.71e-01 81.9% 88.6%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026893 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 52.0 3.97e-01 100.0% 31.7%
4955278 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 49.0 4.46e-01 97.9% 49.6%
3832267 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.73 50.0 4.93e-01 98.9% 66.0%
3754265 603.1.1.187 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DNA_repr_REX1B 0.73 52.0 5.31e-01 100.0% 76.7%
4044288 4207.1.1.6 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med10 0.73 45.0 4.04e-01 98.9% 46.4%
162404 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.72 48.0 4.35e-01 100.0% 50.0%
5047422 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 47.0 4.52e-01 98.9% 60.0%
3742744 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 46.0 4.23e-01 100.0% 50.4%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.71 49.0 4.69e-01 100.0% 61.8%
3938965 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.70 56.0 4.11e-01 86.2% 88.6%
3531746 603.1.1.105 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 0.69 50.0 4.86e-01 75.5% 92.4%
3704699 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 50.0 5.05e-01 75.5% 86.3%
3930310 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.69 48.0 4.92e-01 71.3% 78.7%
3938477 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.69 46.0 4.16e-01 100.0% 50.0%
3939799 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 49.0 4.25e-01 73.4% 67.9%
4977139 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.68 57.0 5.01e-01 89.4% 96.3%
3539335 3874.1.1.4 extended segments › Agnoprotein › Agnoprotein › Agnoprotein › UPF0220 0.68 46.0 4.08e-01 100.0% 47.1%
3757672 604.6.1.23 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › UPF0220 0.68 46.0 4.08e-01 100.0% 47.1%
3509413 601.54.1.4 alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 › UPF0220 0.68 47.0 4.16e-01 100.0% 49.6%
3641813 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.68 48.0 4.85e-01 73.4% 77.9%
3968650 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.68 45.0 4.38e-01 97.9% 61.0%
4457636 604.12.1.77 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PMEI 0.67 46.0 4.61e-01 98.9% 69.5%
4025148 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.67 46.0 4.12e-01 100.0% 49.6%
3236795 601.16.1.2 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT 0.67 55.0 4.84e-01 89.4% 87.9%
3285567 5069.1.1.17 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF6529 0.67 54.0 4.41e-01 87.2% 73.0%
3354508 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 45.0 3.62e-01 100.0% 36.1%
4092993 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.67 51.0 3.24e-01 81.9% 21.6%
3994225 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 51.0 4.43e-01 81.9% 89.0%
4984419 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.66 47.0 3.48e-01 100.0% 28.6%
3786136 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.65 47.0 4.46e-01 75.5% 72.2%
3593230 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 47.0 4.14e-01 75.5% 61.4%
3782650 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 49.0 4.58e-01 77.7% 81.7%
3261541 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 45.0 4.24e-01 100.0% 58.3%
3648687 604.12.1.89 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › CDP-OH_P_transf 0.65 42.0 4.28e-01 95.7% 65.3%
4941521 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.65 43.0 4.35e-01 100.0% 67.4%
3740645 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.65 49.0 4.99e-01 77.7% 86.7%
3202583 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.65 49.0 4.78e-01 77.7% 77.0%
3692512 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 48.0 4.32e-01 77.7% 61.5%
5079046 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.65 55.0 4.88e-01 92.6% 100.0%
3609949 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.65 47.0 3.69e-01 76.6% 56.5%
3912101 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.65 47.0 4.60e-01 75.5% 79.0%
3935599 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.64 56.0 4.48e-01 100.0% 58.5%
3634185 5059.1.1.23 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › DUF2418 0.64 52.0 4.79e-01 89.4% 93.6%
4950225 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.64 50.0 4.65e-01 85.1% 92.5%
4942306 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.64 49.0 4.73e-01 84.0% 100.0%
4220767 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.63 52.0 4.33e-01 89.4% 83.0%
4933188 5069.1.3.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt 0.63 43.0 4.30e-01 100.0% 68.4%
3249720 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 54.0 4.86e-01 94.7% 88.5%
3210941 109.4.1.371 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RTP1_C1 0.63 47.0 3.10e-01 79.8% 30.0%
3710910 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 50.0 3.58e-01 85.1% 46.7%
3700730 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 56.0 4.82e-01 100.0% 88.0%
1222631 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.63 51.0 4.50e-01 86.2% 75.2%
3471396 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.62 44.0 4.45e-01 74.5% 84.2%
3669330 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.61 44.0 4.62e-01 75.5% 88.2%
3510367 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.61 44.0 3.73e-01 75.5% 52.9%
1153944 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.60 51.0 4.57e-01 89.4% 82.4%
3975322 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 51.0 4.70e-01 97.9% 99.2%
3180873 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 41.0 3.52e-01 75.5% 43.9%
3427404 3930.1.1.10 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › DUF5587 0.57 46.0 3.27e-01 87.2% 91.4%
3906128 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.57 44.0 3.70e-01 100.0% 48.8%
148583 109.1.1.1 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C 0.57 48.0 4.39e-01 90.4% 80.8%
3695755 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 42.0 3.34e-01 77.7% 50.0%
5081586 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.55 49.0 3.54e-01 100.0% 52.0%
3221933 3722.1.1.0 alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain 0.55 44.0 3.27e-01 88.3% 34.0%
4301876 109.6.1.3 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N 0.54 48.0 3.66e-01 96.8% 47.9%
None 0.54 46.0 3.56e-01 91.5% 48.5%
3179258 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 47.0 3.55e-01 96.8% 61.7%
3361554 604.15.1.0 alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.54 47.0 4.14e-01 100.0% 69.7%
3285064 207.9.1.3 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pentapeptide repeats › Pentapeptide repeats › Pentapeptide_3 0.53 42.0 3.13e-01 86.2% 42.4%
3706363 650.1.1.1 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.52 42.0 3.90e-01 100.0% 68.3%
3722043 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.52 42.0 3.30e-01 89.4% 48.4%
3368963 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 42.0 3.21e-01 89.4% 37.7%
D2 high residues 111-203
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 43.0 4.59e-01 100.0% 62.7%
3bqoA00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.75 54.0 4.05e-01 74.2% 91.1%
6a7hA01 1.20.140.180 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.73 55.0 4.89e-01 98.9% 56.1%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.72 50.0 4.68e-01 94.6% 60.0%
2v0cA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.72 51.0 4.26e-01 74.2% 62.3%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.71 48.0 4.92e-01 93.5% 71.9%
3hhcC00 1.20.1250.60 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda 0.71 45.0 3.74e-01 90.3% 39.1%
1yuzB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 49.0 4.27e-01 72.0% 50.0%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 49.0 4.06e-01 75.3% 43.5%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 47.0 4.00e-01 98.9% 46.1%
2i9cA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.69 52.0 4.90e-01 93.5% 65.8%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 44.0 4.26e-01 100.0% 58.1%
1oq4A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.67 61.0 4.10e-01 100.0% 77.7%
7z0sE02 1.10.645.10 Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B 0.66 56.0 3.81e-01 91.4% 65.6%
2iiuA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.65 58.0 4.47e-01 97.8% 94.7%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 51.0 4.99e-01 95.7% 76.5%
4m7cB00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.64 49.0 3.78e-01 80.6% 72.2%
4houB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 48.0 3.52e-01 79.6% 50.8%
2jg0A00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.63 55.0 3.37e-01 92.5% 29.4%
3w7tA03 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.62 56.0 3.49e-01 95.7% 42.7%
3dzaA01 1.20.120.1940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain 0.58 50.0 4.60e-01 91.4% 87.2%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.58 45.0 4.23e-01 84.9% 91.3%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.58 51.0 4.80e-01 97.8% 93.8%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.57 49.0 4.00e-01 95.7% 65.7%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 51.0 4.93e-01 96.8% 94.2%
2csxA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 47.0 3.90e-01 91.4% 57.1%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 52.0 4.84e-01 98.9% 83.0%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 48.0 3.84e-01 93.5% 63.6%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 51.0 3.69e-01 100.0% 77.4%
1rfmA01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.55 33.0 2.97e-01 89.2% 41.7%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.54 47.0 4.02e-01 95.7% 72.8%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.53 41.0 4.46e-01 100.0% 100.0%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.53 45.0 3.75e-01 95.7% 68.0%
2dchX01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.50 35.0 3.53e-01 72.0% 83.9%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4386662 3291.1.1.158 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Seryl_tRNA_N 0.84 49.0 4.50e-01 100.0% 47.8%
3623892 150.1.1.109 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › LUC7 0.77 56.0 4.58e-01 74.2% 59.4%
3296047 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.75 52.0 5.50e-01 71.0% 85.9%
None 0.69 51.0 4.06e-01 77.4% 55.7%
3691078 109.4.1.194 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.69 56.0 3.58e-01 87.1% 67.6%
4963594 3684.1.1.55 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF420 0.69 57.0 4.47e-01 88.2% 75.7%
2324029 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.67 63.0 5.65e-01 98.9% 99.2%
4286580 4025.1.1.1 alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › Complex1_49kDa 0.67 56.0 4.06e-01 87.1% 61.7%
4946592 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.67 61.0 4.64e-01 98.9% 93.3%
4181804 4025.1.1.1 alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › Complex1_49kDa 0.67 56.0 4.15e-01 87.1% 65.6%
4553494 4025.1.1.1 alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › Complex1_49kDa 0.67 55.0 3.98e-01 87.1% 58.0%
4483437 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.67 63.0 5.49e-01 98.9% 76.2%
4483577 140.1.1.6 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1,tRNA-synt_1g 0.67 48.0 3.83e-01 75.3% 56.8%
2486892 140.1.1.9 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_3 0.67 49.0 4.10e-01 78.5% 100.0%
4990841 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 55.0 3.30e-01 96.8% 14.3%
4978529 4025.1.1.1 alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › Complex1_49kDa 0.66 54.0 4.14e-01 87.1% 71.5%
4996451 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.65 50.0 3.50e-01 84.9% 27.4%
5035080 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.65 56.0 4.64e-01 91.4% 80.0%
4958325 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 57.0 4.65e-01 93.5% 87.3%
3978919 604.10.1.1 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA 0.64 51.0 4.81e-01 95.7% 70.9%
5058485 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 59.0 5.44e-01 98.9% 92.2%
3221738 192.29.1.172 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.63 58.0 5.02e-01 98.9% 82.1%
3424324 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.63 55.0 4.26e-01 94.6% 57.5%
3578532 109.2.1.5 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Trehalase 0.63 54.0 3.72e-01 92.5% 46.3%
5041267 5039.1.1.2 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › DUF420 0.63 58.0 4.85e-01 98.9% 90.6%
5041256 601.4.1.91 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF30769 0.63 57.0 5.52e-01 100.0% 97.1%
2856784 109.2.1.42 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › MGH1-like_GH 0.62 56.0 3.78e-01 95.7% 63.3%
4616055 5059.1.1.2 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res 0.62 57.0 5.40e-01 100.0% 99.1%
4028858 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.61 57.0 5.14e-01 100.0% 87.9%
5019209 109.2.1.2 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_15 0.61 53.0 3.83e-01 90.3% 57.4%
4926931 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.61 54.0 3.83e-01 100.0% 43.3%
3249529 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.60 54.0 4.81e-01 100.0% 90.4%
4935430 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.60 55.0 5.27e-01 98.9% 100.0%
3974221 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 54.0 4.83e-01 100.0% 86.2%
3420616 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.60 53.0 3.99e-01 98.9% 60.1%
4934669 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.59 50.0 3.48e-01 94.6% 78.8%
3629399 1075.4.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.58 52.0 3.40e-01 94.6% 77.7%
4118682 601.18.1.22 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › FTR1 0.57 47.0 4.93e-01 88.2% 100.0%
3608673 109.4.1.194 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.57 48.0 3.24e-01 91.4% 47.5%
3595093 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.56 49.0 3.75e-01 95.7% 54.8%
3931278 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.56 50.0 4.78e-01 98.9% 94.4%
5066789 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.55 44.0 4.64e-01 95.7% 96.5%
3706947 140.1.1.8 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1g,Anticodon_3 0.55 48.0 3.71e-01 95.7% 56.1%
4384717 140.1.1.8 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1g,Anticodon_3 0.55 48.0 3.59e-01 95.7% 59.1%
3615494 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.55 47.0 2.99e-01 90.3% 85.8%
2773193 2002.1.1.173 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › GH123_cat 0.54 41.0 2.73e-01 82.8% 77.4%
4168977 140.1.1.8 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1g,Anticodon_3 0.54 46.0 3.52e-01 95.7% 51.8%
3373822 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 46.0 2.95e-01 100.0% 74.3%