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MH925091.1__QAY01824.1__ValSw41_1__00001
Bact-VirMH925091.1__QAY01824.1__ValSw41_1__00001
Identity
- Accession:
- MH925091 ↗
- Kingdom:
- phage
Quality
76.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 95-221
Domain cluster:
rep: MG543995.1__ATW69300.1__CJF57_00137__00137__D14-117
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00391.30 best | PEP-utilizers | 56.5 | 2.30e-15 | 63.0% | 94.4% |
D2
medium
residues 1-55
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01326.25 best | PPDK_N | 40.8 | 2.40e-10 | 98.2% | 14.5% |
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1kblA06 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.90 | 82.0 | 6.54e-01 | 100.0% | 54.1% |
| 2olsA02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.85 | 78.0 | 5.61e-01 | 100.0% | 71.3% |
| 5hv6A02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.80 | 71.0 | 5.38e-01 | 100.0% | 69.0% |
| 2pn1A03 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.74 | 56.0 | 4.39e-01 | 100.0% | 38.3% |
| 4dimA03 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.73 | 65.0 | 4.29e-01 | 100.0% | 31.3% |
| 5i47B03 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.66 | 53.0 | 4.53e-01 | 100.0% | 53.7% |
| 7qprA02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.66 | 51.0 | 3.86e-01 | 83.6% | 88.1% |
| 4jpdA00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.66 | 46.0 | 3.74e-01 | 74.5% | 59.6% |
| 1dcoA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.66 | 49.0 | 4.02e-01 | 80.0% | 81.8% |
| 6u26A01 | 3.30.70.80 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 | 0.66 | 47.0 | 4.02e-01 | 74.5% | 87.5% |
| 2a8eA00 | 3.30.930.20 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Protein of unknown function DUF1054 | 0.64 | 49.0 | 3.34e-01 | 85.5% | 42.4% |
| 1k8kD02 | 3.30.1460.20 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.64 | 43.0 | 3.25e-01 | 70.9% | 90.8% |
| 2q7eA02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.63 | 44.0 | 2.95e-01 | 72.7% | 50.5% |
| 2x7gA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.63 | 43.0 | 3.73e-01 | 70.9% | 100.0% |
| 3upsA00 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.61 | 41.0 | 3.34e-01 | 70.9% | 38.0% |
| 3kztA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.61 | 47.0 | 3.66e-01 | 87.3% | 95.5% |
| 2nvmA00 | 3.30.310.110 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like | 0.61 | 43.0 | 3.55e-01 | 74.5% | 70.2% |
| 3jyuA02 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.60 | 42.0 | 3.58e-01 | 72.7% | 67.8% |
| 1tkjA00 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.60 | 45.0 | 2.93e-01 | 83.6% | 89.5% |
| 2pm6D01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.59 | 49.0 | 3.15e-01 | 96.4% | 37.9% |
| 2mh9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 46.0 | 3.51e-01 | 85.5% | 89.8% |
| 5awwY00 | 1.10.3370.10 | Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain | 0.58 | 50.0 | 3.02e-01 | 100.0% | 50.9% |
| 1qlmA02 | 3.30.1030.10 | Alpha Beta › 2-Layer Sandwich › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 › Methenyltetrahydromethanopterin Cyclohydrolase; Chain A, domain 2 | 0.58 | 46.0 | 3.29e-01 | 96.4% | 55.1% |
| 6p66D01 | 3.40.91.30 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.58 | 41.0 | 3.25e-01 | 74.5% | 37.6% |
| 6kbyA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.58 | 46.0 | 2.86e-01 | 92.7% | 93.9% |
| 1zcdA00 | 1.20.1530.10 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain | 0.58 | 49.0 | 3.04e-01 | 100.0% | 88.6% |
| 2ffgA00 | 3.30.720.20 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Protein of unknown function DUF1797 | 0.58 | 43.0 | 3.81e-01 | 80.0% | 55.0% |
| 1i5eA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 41.0 | 2.80e-01 | 76.4% | 73.1% |
| 7qssA01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.57 | 37.0 | 2.63e-01 | 70.9% | 19.1% |
| 2xssA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.57 | 43.0 | 3.09e-01 | 81.8% | 30.8% |
| 2l72A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.57 | 42.0 | 3.36e-01 | 81.8% | 38.1% |
| 2g0iA00 | 3.30.70.1490 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp | 0.56 | 45.0 | 3.67e-01 | 90.9% | 94.6% |
| 2dt8A02 | 3.30.1180.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › | 0.56 | 41.0 | 3.30e-01 | 100.0% | 35.4% |
| 2avxA00 | 3.30.450.80 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain | 0.56 | 39.0 | 2.83e-01 | 74.5% | 68.4% |
| 3p9aF00 | 1.10.132.80 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.56 | 41.0 | 3.03e-01 | 81.8% | 32.1% |
| 4nehA01 | 2.130.10.130 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Integrin alpha, N-terminal | 0.56 | 47.0 | 2.87e-01 | 100.0% | 44.4% |
| 2retA00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.55 | 41.0 | 3.64e-01 | 81.8% | 53.6% |
| 2qrdE01 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.55 | 41.0 | 3.04e-01 | 87.3% | 36.1% |
| 2xf1A00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.54 | 39.0 | 3.18e-01 | 83.6% | 36.9% |
| 2mzwA01 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.54 | 41.0 | 3.75e-01 | 85.5% | 81.6% |
| 5cm2Z00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 35.0 | 2.51e-01 | 70.9% | 32.6% |
| 5j3uA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.52 | 41.0 | 3.25e-01 | 90.9% | 99.2% |
| 2f51A00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.52 | 43.0 | 3.53e-01 | 98.2% | 86.5% |
| 4yg6B00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.51 | 41.0 | 3.12e-01 | 100.0% | 97.5% |
| 2iuwA00 | 2.60.120.590 | Mainly Beta › Sandwich › Jelly Rolls › Alpha-ketoglutarate-dependent dioxygenase AlkB-like | 0.51 | 44.0 | 3.03e-01 | 100.0% | 59.0% |
| 2vs7A02 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.51 | 35.0 | 3.21e-01 | 74.5% | 51.3% |
| 2ljwA00 | 3.30.428.40 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › Protein of unknown function DUF3067 | 0.51 | 46.0 | 3.71e-01 | 100.0% | 54.8% |
| 4e1oA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.51 | 39.0 | 3.27e-01 | 85.5% | 83.7% |
| 3cxgA00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.51 | 43.0 | 3.41e-01 | 100.0% | 77.9% |
| 2z86D02 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.50 | 39.0 | 2.68e-01 | 96.4% | 82.7% |
ECOD (73)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3955993 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.94 | 84.0 | 4.97e-01 | 100.0% | 15.5% |
| 4991809 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.93 | 83.0 | 4.78e-01 | 100.0% | 12.7% |
| 4975876 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.91 | 83.0 | 4.85e-01 | 100.0% | 14.3% |
| 5019790 | 206.1.3.117 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PEP-utilizers_C | 0.90 | 81.0 | 4.42e-01 | 100.0% | 7.1% |
| 4430492 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.88 | 83.0 | 4.54e-01 | 100.0% | 7.9% |
| 4589832 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.88 | 77.0 | 4.53e-01 | 100.0% | 14.6% |
| 5058176 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.88 | 82.0 | 5.04e-01 | 100.0% | 23.6% |
| 3598953 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.87 | 82.0 | 4.75e-01 | 100.0% | 19.2% |
| 4176014 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.86 | 79.0 | 4.83e-01 | 100.0% | 30.3% |
| 5051783 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.85 | 79.0 | 4.75e-01 | 100.0% | 28.7% |
| 5060111 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.85 | 78.0 | 4.60e-01 | 100.0% | 23.9% |
| 3242790 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.84 | 77.0 | 4.75e-01 | 100.0% | 22.7% |
| 3282114 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.84 | 77.0 | 4.69e-01 | 100.0% | 29.8% |
| 4973990 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.83 | 75.0 | 4.59e-01 | 100.0% | 28.9% |
| 3278788 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.80 | 71.0 | 4.54e-01 | 100.0% | 25.5% |
| 3672866 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.80 | 72.0 | 4.36e-01 | 100.0% | 29.4% |
| 3312365 | 206.1.3.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N | 0.79 | 71.0 | 4.31e-01 | 100.0% | 37.3% |
| 3766984 | 304.120.1.15 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › PF29952 | 0.76 | 54.0 | 4.51e-01 | 76.4% | 43.2% |
| 3848891 | 304.151.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › PF29952 | 0.76 | 54.0 | 4.43e-01 | 76.4% | 41.0% |
| 3894542 | 11.1.1.978 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29952 | 0.76 | 54.0 | 4.60e-01 | 78.2% | 46.7% |
| 3898704 | 304.151.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › PF29952 | 0.76 | 54.0 | 4.52e-01 | 78.2% | 44.2% |
| 4446761 | 3433.1.2.0 ↗ | a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Chromosome-encoded ParB dimerization domain | 0.73 | 49.0 | 4.95e-01 | 78.2% | 70.9% |
| 413788 | 206.1.3.13 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › GSP_synth | 0.68 | 56.0 | 3.88e-01 | 90.9% | 69.7% |
| 5045683 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.67 | 46.0 | 2.90e-01 | 70.9% | 38.2% |
| 3939986 | 864.1.1.3 ↗ | a+b two layers › DLC › DLC › DLC › Ground-like | 0.66 | 48.0 | 4.14e-01 | 78.2% | 65.6% |
| 4215095 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.66 | 48.0 | 2.95e-01 | 78.2% | 33.8% |
| 5067363 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.66 | 45.0 | 4.02e-01 | 70.9% | 47.5% |
| 5043492 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.65 | 44.0 | 3.65e-01 | 70.9% | 43.4% |
| 3477897 | 304.44.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 | 0.64 | 45.0 | 3.83e-01 | 74.5% | 74.4% |
| 4949572 | 328.8.1.1 ↗ | a+b two layers › IF3-like › Schlafen 8 › Schlafen 8 › SLFN_AlbA_2 | 0.63 | 43.0 | 3.36e-01 | 72.7% | 31.2% |
| 4944466 | 301.13.1.0 ↗ | a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain | 0.63 | 45.0 | 3.44e-01 | 74.5% | 38.4% |
| 3413369 | 304.151.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase | 0.62 | 44.0 | 3.41e-01 | 76.4% | 33.8% |
| 4330210 | 327.6.1.6 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › Secretin | 0.62 | 42.0 | 2.63e-01 | 70.9% | 14.1% |
| 4951664 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.62 | 44.0 | 3.21e-01 | 74.5% | 27.3% |
| 5004330 | 328.8.1.1 ↗ | a+b two layers › IF3-like › Schlafen 8 › Schlafen 8 › SLFN_AlbA_2 | 0.61 | 41.0 | 3.29e-01 | 70.9% | 34.2% |
| 4506985 | 328.3.1.2 ↗ | a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain › mIF3 | 0.61 | 42.0 | 3.43e-01 | 78.2% | 38.1% |
| 4400484 | 223.1.1.3 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › GAF | 0.60 | 43.0 | 3.05e-01 | 76.4% | 66.9% |
| 5029644 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.60 | 42.0 | 3.45e-01 | 74.5% | 43.8% |
| 3628907 | 101.1.2.394 ↗ | alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1 | 0.60 | 44.0 | 2.41e-01 | 80.0% | 10.3% |
| 4934098 | 304.19.1.1 ↗ | a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha | 0.59 | 40.0 | 3.49e-01 | 76.4% | 44.7% |
| 5048661 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.59 | 44.0 | 2.63e-01 | 80.0% | 58.4% |
| 4669669 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.59 | 40.0 | 3.25e-01 | 70.9% | 39.1% |
| 3970771 | 3009.1.1.0 ↗ | alpha arrays › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like | 0.59 | 50.0 | 3.42e-01 | 94.5% | 64.1% |
| 5021275 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.59 | 48.0 | 3.88e-01 | 90.9% | 86.4% |
| 5068574 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.59 | 43.0 | 2.82e-01 | 83.6% | 44.0% |
| 2810200 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.59 | 44.0 | 4.16e-01 | 81.8% | 86.6% |
| 5002173 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.59 | 49.0 | 4.19e-01 | 94.5% | 100.0% |
| 2834311 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.58 | 43.0 | 4.27e-01 | 80.0% | 77.6% |
| 5033504 | 2011.1.1.8 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 | 0.58 | 47.0 | 3.08e-01 | 94.5% | 72.1% |
| 1179535 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.57 | 42.0 | 4.01e-01 | 81.8% | 98.5% |
| 4873577 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.57 | 43.0 | 3.12e-01 | 85.5% | 32.7% |
| 141070 | 223.3.1.1 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.57 | 41.0 | 4.15e-01 | 80.0% | 89.5% |
| 1762378 | 223.3.1.3 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.57 | 42.0 | 3.98e-01 | 80.0% | 96.9% |
| 4995146 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.56 | 38.0 | 3.25e-01 | 70.9% | 84.4% |
| 1641233 | 4019.1.1.3 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase | 0.56 | 41.0 | 2.95e-01 | 80.0% | 39.8% |
| 4931077 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.56 | 45.0 | 3.29e-01 | 100.0% | 93.7% |
| 2323881 | 3433.1.2.1 ↗ | a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Chromosome-encoded ParB dimerization domain › ParB_dimer | 0.56 | 36.0 | 3.70e-01 | 74.5% | 68.5% |
| 3788427 | 101.1.2.207 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFC3_eWH | 0.56 | 41.0 | 3.35e-01 | 78.2% | 77.0% |
| 5036264 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.56 | 40.0 | 3.40e-01 | 81.8% | 77.1% |
| 3310256 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.55 | 39.0 | 3.31e-01 | 76.4% | 72.2% |
| 4993850 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.54 | 38.0 | 3.22e-01 | 74.5% | 42.1% |
| 3306699 | 101.1.2.517 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD | 0.54 | 46.0 | 2.83e-01 | 98.2% | 65.2% |
| 2642882 | 223.3.1.0 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins | 0.54 | 39.0 | 3.94e-01 | 76.4% | 78.2% |
| 1278602 | 223.3.1.1 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.54 | 40.0 | 3.94e-01 | 87.3% | 76.7% |
| 420847 | 224.1.1.1 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF | 0.54 | 38.0 | 3.13e-01 | 83.6% | 36.7% |
| 3732955 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.53 | 37.0 | 2.99e-01 | 76.4% | 37.4% |
| 3957084 | 4019.1.1.1 ↗ | alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.52 | 35.0 | 3.16e-01 | 72.7% | 48.8% |
| 4944239 | 301.13.1.0 ↗ | a+b three layers › Bacillus chorismate mutase-like › DAK1/DegV C-terminal domain › DAK1/DegV C-terminal domain | 0.52 | 38.0 | 3.05e-01 | 100.0% | 35.4% |
| 3737786 | 580.1.1.1 ↗ | extended segments › Epsilon subunit of mitochondrial F1F0-ATP synthase › Epsilon subunit of mitochondrial F1F0-ATP synthase › Epsilon subunit of mitochondrial F1F0-ATP synthase › ATP-synt_Eps | 0.51 | 36.0 | 3.66e-01 | 74.5% | 100.0% |
| 864441 | 223.3.1.1 ↗ | a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Beta-lactamase | 0.51 | 36.0 | 3.65e-01 | 98.2% | 77.6% |
| 4837926 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.51 | 37.0 | 4.02e-01 | 89.1% | 100.0% |
| 185814 | 101.1.4.12 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › MSC | 0.50 | 39.0 | 3.46e-01 | 87.3% | 97.6% |
| 4023426 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.50 | 41.0 | 3.86e-01 | 98.2% | 75.7% |
D3
medium
residues 56-94_222-236
Domain cluster:
representative
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vbgA04 | 1.10.189.10 | Mainly Alpha › Orthogonal Bundle › Pyruvate Phosphate di-kinase; domain 2 › Pyruvate Phosphate Dikinase, domain 2 | 0.84 | 74.0 | 7.06e-01 | 98.1% | 93.7% |
| 1kblA02 | 1.10.189.10 | Mainly Alpha › Orthogonal Bundle › Pyruvate Phosphate di-kinase; domain 2 › Pyruvate Phosphate Dikinase, domain 2 | 0.77 | 67.0 | 6.39e-01 | 98.1% | 93.7% |
| 2x0sA04 | 1.10.189.10 | Mainly Alpha › Orthogonal Bundle › Pyruvate Phosphate di-kinase; domain 2 › Pyruvate Phosphate Dikinase, domain 2 | 0.77 | 66.0 | 6.27e-01 | 98.1% | 93.8% |
| 1oxjA02 | 1.25.40.170 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain | 0.71 | 63.0 | 4.96e-01 | 98.1% | 54.1% |
| 2h7oA01 | 1.20.120.1330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain | 0.71 | 62.0 | 4.76e-01 | 100.0% | 49.6% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 59.0 | 4.51e-01 | 100.0% | 72.3% |
| 3beeA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 53.0 | 4.54e-01 | 100.0% | 54.9% |
| 3b1fA02 | 1.10.3660.10 | Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain | 0.65 | 47.0 | 3.77e-01 | 77.8% | 39.6% |
| 3hq2B00 | 1.10.1370.30 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › | 0.65 | 54.0 | 3.16e-01 | 98.1% | 17.5% |
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 54.0 | 3.99e-01 | 100.0% | 39.6% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.62 | 43.0 | 2.52e-01 | 72.2% | 8.3% |
| 5b00A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.62 | 50.0 | 3.33e-01 | 100.0% | 44.4% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 50.0 | 4.07e-01 | 98.1% | 82.1% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.60 | 52.0 | 4.48e-01 | 100.0% | 76.4% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.60 | 45.0 | 4.66e-01 | 90.7% | 88.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 50.0 | 4.45e-01 | 100.0% | 77.6% |
| 3p26A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 49.0 | 3.30e-01 | 98.1% | 70.7% |
| 1ya0A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 47.0 | 3.25e-01 | 100.0% | 25.2% |
| 1n00A03 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.55 | 45.0 | 4.21e-01 | 98.1% | 75.3% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.55 | 41.0 | 3.85e-01 | 81.5% | 65.7% |
| 2cr7A01 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.55 | 42.0 | 4.08e-01 | 98.1% | 73.0% |
| 4zhbA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.55 | 44.0 | 3.76e-01 | 100.0% | 52.9% |
| 2kobA01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.55 | 41.0 | 3.57e-01 | 94.4% | 50.5% |
| 3vfzB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 38.0 | 3.71e-01 | 90.7% | 66.7% |
| 2vg0A00 | 3.40.1180.10 | Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like | 0.53 | 45.0 | 3.03e-01 | 100.0% | 30.4% |
| 1bcrA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 45.0 | 2.94e-01 | 100.0% | 29.1% |
| 6hxpA01 | 1.10.230.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 | 0.52 | 44.0 | 3.64e-01 | 96.3% | 100.0% |
| 1ghcA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 43.0 | 3.93e-01 | 100.0% | 92.0% |
| 2honA02 | 1.20.1250.30 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 37.0 | 2.87e-01 | 83.3% | 31.5% |
| 3ed5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.51 | 45.0 | 3.80e-01 | 94.4% | 63.1% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.51 | 44.0 | 3.70e-01 | 94.4% | 61.1% |
| 4f88102 | 3.90.1720.60 | Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › | 0.50 | 35.0 | 2.37e-01 | 74.1% | 50.2% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3904744 | 109.4.1.434 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAST_1 | 0.69 | 59.0 | 3.52e-01 | 100.0% | 12.7% |
| 4587007 | 3718.1.1.0 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT | 0.67 | 60.0 | 4.87e-01 | 100.0% | 66.0% |
| 3205408 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 58.0 | 3.19e-01 | 100.0% | 7.4% |
| 3580322 | 604.17.1.2 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like › PF30475 | 0.66 | 57.0 | 5.19e-01 | 100.0% | 78.7% |
| 3595734 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 55.0 | 4.18e-01 | 100.0% | 74.3% |
| 3924197 | 109.4.1.517 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med24_N | 0.64 | 56.0 | 3.06e-01 | 100.0% | 9.3% |
| 3282853 | 191.1.1.8 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_33 | 0.63 | 54.0 | 3.90e-01 | 98.1% | 51.9% |
| 3214956 | 207.1.1.20 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_4 | 0.61 | 49.0 | 3.16e-01 | 100.0% | 17.8% |
| 4993165 | 101.1.11.203 ↗ | alpha arrays › HTH › HTH › Ribbon-helix-helix › UPF0175 | 0.61 | 48.0 | 3.97e-01 | 100.0% | 48.4% |
| 3797672 | 109.27.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain | 0.60 | 50.0 | 4.43e-01 | 100.0% | 80.0% |
| 4033267 | 4317.1.1.1 ↗ | a+b duplicates or obligate multimers › YdfO-like › YdfO-like › YdfO-like › DUF1398 | 0.60 | 48.0 | 4.65e-01 | 88.9% | 95.0% |
| 3611408 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 49.0 | 3.59e-01 | 100.0% | 38.2% |
| 3287061 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.59 | 49.0 | 3.95e-01 | 100.0% | 86.7% |
| 4948614 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.57 | 50.0 | 3.17e-01 | 100.0% | 80.4% |
| 3932177 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.56 | 46.0 | 3.51e-01 | 100.0% | 36.7% |
| 3227171 | 207.1.1.104 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_Zer-1 | 0.55 | 49.0 | 3.08e-01 | 100.0% | 21.7% |
| 3287859 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.55 | 47.0 | 3.76e-01 | 100.0% | 80.9% |
| 3806239 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.55 | 44.0 | 4.00e-01 | 90.7% | 76.0% |
| 3571420 | 220.1.1.130 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_21 | 0.55 | 43.0 | 3.15e-01 | 100.0% | 48.7% |
D4
medium
residues 237-374