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AZF89938.1

Arc-Vir

MK170447__AZF89938.1__X__00050

Identity

Accession:
MK170447 ↗
Protein ID:
AZF89938.1 ↗
Kingdom:
archaea

Quality

81.4 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Methanosarcina_virus_MetMV

TaxID: 2488574

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 65-221
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.74 52.0 4.81e-01 72.6% 67.0%
2k73A00 1.20.1550.10 Mainly Alpha › Up-down Bundle › Bromodomain-like › DsbB-like 0.66 47.0 4.50e-01 72.6% 85.8%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 41.0 4.96e-01 72.0% 96.1%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.65 46.0 4.37e-01 72.6% 71.9%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 39.0 4.80e-01 94.9% 94.0%
2rgnB01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.62 45.0 4.15e-01 73.9% 73.5%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 50.0 4.75e-01 86.6% 93.8%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.61 44.0 4.01e-01 74.5% 76.4%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.61 44.0 4.13e-01 72.6% 76.2%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 50.0 4.54e-01 86.6% 72.6%
3q1xA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.60 31.0 3.33e-01 71.3% 55.4%
4k1pE00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.59 55.0 4.28e-01 100.0% 96.0%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.59 40.0 4.20e-01 72.0% 74.8%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.59 46.0 4.26e-01 82.2% 75.2%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.58 38.0 4.06e-01 70.1% 75.4%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.57 36.0 3.70e-01 85.4% 64.7%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 44.0 4.56e-01 94.9% 84.2%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 42.0 4.30e-01 94.9% 78.8%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 45.0 4.42e-01 94.9% 77.5%
7zdtD01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.55 45.0 3.50e-01 86.0% 82.8%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 4.31e-01 94.9% 85.7%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.54 49.0 3.85e-01 100.0% 100.0%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 43.0 4.46e-01 84.7% 91.0%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 40.0 4.34e-01 82.8% 92.5%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 36.0 3.91e-01 96.8% 82.0%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 37.0 3.99e-01 89.2% 85.6%
4xi0F00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 36.0 3.49e-01 84.1% 62.9%
6tejB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.52 42.0 3.39e-01 85.4% 84.8%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 36.0 3.95e-01 72.0% 88.3%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 34.0 3.81e-01 73.9% 89.2%
2nxpB00 1.25.40.500 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain 0.50 31.0 3.23e-01 88.5% 64.1%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4001943 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.74 52.0 5.89e-01 72.6% 97.5%
3620861 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 52.0 5.57e-01 72.6% 85.9%
3999007 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.71 49.0 4.98e-01 70.1% 97.4%
3214883 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.70 50.0 4.99e-01 72.6% 93.1%
3219759 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 50.0 5.29e-01 72.6% 94.8%
3592689 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 49.0 5.02e-01 72.6% 94.7%
3606295 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.68 50.0 4.67e-01 74.5% 78.4%
3908126 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.68 48.0 5.03e-01 72.0% 95.0%
3273336 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.67 47.0 4.11e-01 72.6% 91.0%
3734606 604.5.1.8 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2 0.66 48.0 4.35e-01 74.5% 90.2%
3616490 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 47.0 4.78e-01 72.0% 88.0%
5026838 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.66 46.0 3.98e-01 71.3% 84.1%
3927159 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 47.0 4.92e-01 72.6% 90.7%
4952530 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.66 46.0 4.94e-01 72.6% 83.7%
3243879 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 46.0 5.07e-01 72.0% 91.2%
3687571 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.64 41.0 4.36e-01 70.7% 72.1%
3464835 611.9.1.4 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.63 37.0 4.14e-01 87.3% 72.0%
3463576 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.63 44.0 3.91e-01 70.1% 69.5%
3330802 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 46.0 4.64e-01 74.5% 78.6%
3689489 604.5.1.8 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2 0.63 45.0 4.03e-01 74.5% 93.8%
4285620 5000.4.1.5 ↗ alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › PF27742 0.61 50.0 4.54e-01 87.3% 96.3%
3282142 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.61 44.0 4.62e-01 74.5% 82.1%
3212831 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.61 42.0 4.04e-01 70.7% 67.0%
3459287 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 42.0 4.17e-01 70.1% 78.2%
4102297 3834.1.1.10 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › PF27870 0.60 43.0 3.32e-01 72.6% 96.5%
3860471 150.1.1.31 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.60 44.0 3.94e-01 74.5% 69.1%
3214563 5001.1.1.35 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx 0.60 48.0 3.96e-01 85.4% 92.9%
4388445 5000.4.1.4 ↗ alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › PF28873 0.60 49.0 4.35e-01 87.3% 82.6%
3228529 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 43.0 4.40e-01 72.6% 82.0%
4874833 601.19.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.59 41.0 4.15e-01 70.7% 80.5%
3215510 601.16.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.56 39.0 4.12e-01 70.7% 79.3%
3453619 601.4.1.12 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.55 39.0 4.00e-01 73.9% 74.2%
3833041 601.1.1.93 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1216 0.54 43.0 4.50e-01 83.4% 96.4%
5078221 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.54 38.0 3.95e-01 72.0% 77.9%
3207391 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.54 38.0 3.98e-01 79.6% 78.6%
4045652 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.52 43.0 3.45e-01 88.5% 84.0%
3165172 3890.1.1.1 ↗ alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.52 43.0 3.98e-01 86.6% 96.0%
3721451 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.52 42.0 4.16e-01 85.4% 90.6%
4379341 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 36.0 3.45e-01 70.7% 92.8%
3169936 3890.1.1.1 ↗ alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.52 42.0 3.76e-01 86.6% 95.0%
5064159 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.51 40.0 3.62e-01 81.5% 73.2%
3694381 3890.1.1.1 ↗ alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.51 42.0 3.78e-01 86.6% 92.5%
4622994 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.51 42.0 3.33e-01 88.5% 83.7%
3304974 3684.1.1.2 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.50 45.0 3.68e-01 95.5% 80.4%
4997036 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.50 35.0 3.39e-01 70.7% 87.0%
4601497 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.50 35.0 3.40e-01 70.1% 80.0%
3193531 1075.4.1.5 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Iron_permease 0.50 41.0 3.07e-01 86.0% 58.2%
5000600 1075.5.1.4 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.50 41.0 3.68e-01 87.3% 82.3%
3221532 601.1.2.76 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › ATP-synt_C 0.50 36.0 3.50e-01 74.5% 90.5%
D2 medium residues 9-64
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF27195.1 best YdhT_N 32.7 6.40e-08 94.6% 86.4%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5yc9B01 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.53 37.0 3.23e-01 92.9% 44.3%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3193829 101.1.2.306 ↗ alpha arrays › HTH › HTH › winged helix domain › NPR2 0.55 45.0 3.78e-01 98.2% 53.3%