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AZF89963.1

Arc-Vir

MK170447__AZF89963.1__X__00044

Identity

Accession:
MK170447 ↗
Protein ID:
AZF89963.1 ↗
Kingdom:
archaea

Quality

77.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-53
PDB
Domain cluster: representative
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qz8A01 2.40.10.250 Mainly Beta › Beta Barrel › Thrombin, subunit H › Replicase NSP9 0.73 59.0 4.73e-01 90.6% 57.1%
2ptfA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.73 63.0 4.57e-01 98.1% 83.0%
2j3vA02 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.70 60.0 4.04e-01 100.0% 63.7%
6toaF01 3.30.2000.30 Alpha Beta › 2-Layer Sandwich › STM4215-like › 0.69 55.0 4.29e-01 94.3% 63.8%
1dw9A02 3.30.1160.10 Alpha Beta › 2-Layer Sandwich › Cyanate Lyase; Chain: A, domain 2 › Cyanate lyase, C-terminal domain 0.69 53.0 4.90e-01 84.9% 85.3%
3e23A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 57.0 3.89e-01 96.2% 50.0%
3sm3A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 58.0 3.89e-01 98.1% 59.4%
1d5aA01 3.30.342.10 Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 0.68 54.0 4.01e-01 92.5% 52.3%
5ejlA02 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.67 56.0 4.34e-01 96.2% 56.5%
5aj3E01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.67 47.0 4.21e-01 77.4% 61.7%
2y8yA02 3.30.70.1210 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 0.65 54.0 4.34e-01 98.1% 68.7%
2bi0A01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.64 50.0 3.68e-01 88.7% 85.6%
2ii3A01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.64 51.0 3.52e-01 96.2% 79.9%
1vq8R00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.63 50.0 3.78e-01 96.2% 90.7%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 50.0 4.17e-01 96.2% 98.1%
3c0wA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.62 53.0 4.08e-01 96.2% 52.5%
3ahpA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 50.0 4.16e-01 98.1% 99.1%
4i6yA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.61 49.0 4.00e-01 94.3% 66.4%
4hudA01 3.30.2000.40 Alpha Beta › 2-Layer Sandwich › STM4215-like › Myoviridae tail sheath stabiliser 0.61 48.0 3.37e-01 96.2% 46.2%
2wyhA05 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 48.0 3.63e-01 88.7% 68.7%
2i6gB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 48.0 3.39e-01 96.2% 88.9%
3x1lB03 2.60.40.4350 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 49.0 4.13e-01 100.0% 64.8%
7r5mA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.60 47.0 3.23e-01 92.5% 77.6%
2vlgC00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.60 47.0 3.98e-01 94.3% 99.0%
2ab5B01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.60 50.0 3.85e-01 98.1% 57.8%
4m3sA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.59 48.0 3.49e-01 92.5% 52.2%
1ciyA02 2.100.10.10 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Pesticidal crystal protein, central domain 0.59 47.0 3.29e-01 94.3% 98.5%
3l60A01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.59 45.0 3.21e-01 96.2% 80.0%
1vwxP00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.59 47.0 3.59e-01 100.0% 90.8%
3lvtA03 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 47.0 3.76e-01 100.0% 71.3%
7pzoA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.58 47.0 3.96e-01 94.3% 67.7%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 46.0 3.02e-01 92.5% 20.4%
7k0xA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 46.0 4.22e-01 96.2% 70.5%
3vmnA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.57 45.0 3.46e-01 94.3% 45.1%
1vs3A02 3.30.70.660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Pseudouridine synthase I, catalytic domain, C-terminal subdomain 0.56 44.0 3.41e-01 94.3% 61.1%
3dwoX00 2.40.160.60 Mainly Beta › Beta Barrel › Porin › Outer membrane protein transport protein (OMPP1/FadL/TodX) 0.56 42.0 2.48e-01 83.0% 18.0%
1ekrA00 3.30.70.640 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Molybdopterin cofactor biosynthesis C (MoaC) domain 0.56 44.0 3.39e-01 94.3% 59.4%
3u83A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 45.0 3.82e-01 98.1% 66.3%
3ayhB01 3.30.1490.120 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase Rpb7-like, N-terminal domain 0.56 45.0 4.06e-01 96.2% 86.1%
4q52A00 2.60.40.3910 Mainly Beta › Sandwich › Immunoglobulin-like › Inclusion body protein 0.55 46.0 3.31e-01 100.0% 80.6%
4v19W00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.55 45.0 3.28e-01 98.1% 59.0%
1ilvA00 3.40.1210.10 Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase 0.54 38.0 2.60e-01 77.4% 52.2%
3io1A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 44.0 3.56e-01 98.1% 63.8%
2fwvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 37.0 2.60e-01 73.6% 20.0%
3o4oB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 44.0 3.60e-01 98.1% 59.6%
6qdws00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.53 43.0 3.55e-01 96.2% 93.6%
2vtwA00 2.60.90.30 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Fiber protein 1, C-terminal domain 0.53 40.0 2.92e-01 94.3% 52.2%
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 36.0 2.39e-01 73.6% 80.2%
4x28C02 2.40.110.10 Mainly Beta › Beta Barrel › Butyryl-CoA Dehydrogenase, subunit A; domain 2 › Butyryl-CoA Dehydrogenase, subunit A, domain 2 0.53 40.0 3.35e-01 86.8% 58.4%
4of8A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 42.0 3.59e-01 100.0% 59.2%
5ib9A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.52 39.0 2.62e-01 90.6% 34.7%
3pfeA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 43.0 3.34e-01 98.1% 71.5%
2p8jA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 40.0 2.93e-01 100.0% 94.7%
2f7vA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 42.0 3.50e-01 98.1% 70.4%
3gb0A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 42.0 3.42e-01 96.2% 64.3%
5x8tT00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.51 42.0 3.21e-01 98.1% 67.4%
3iuzA00 3.10.180.50 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 0.50 39.0 2.56e-01 98.1% 70.6%
6w1kA01 3.10.180.50 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 0.50 41.0 2.65e-01 98.1% 80.5%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4118093 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.79 70.0 4.94e-01 98.1% 80.0%
4968263 1.1.5.91 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_C 0.77 67.0 4.38e-01 98.1% 50.5%
3946057 304.102.1.1 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_2 0.77 65.0 4.28e-01 96.2% 43.9%
5067070 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.76 66.0 4.85e-01 98.1% 72.9%
5027270 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.75 65.0 4.53e-01 98.1% 61.1%
3948250 304.124.1.9 a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like › Phage_tail_terminator_9 0.75 63.0 4.55e-01 96.2% 65.2%
3602499 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.74 64.0 4.81e-01 98.1% 71.5%
4992907 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.74 64.0 4.61e-01 98.1% 64.5%
4659258 2003.1.5.51 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › TPMT 0.74 64.0 4.28e-01 100.0% 45.1%
4034134 304.124.1.0 a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like 0.72 57.0 4.42e-01 90.6% 64.8%
4988254 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.72 60.0 4.23e-01 98.1% 56.7%
3943282 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.72 59.0 4.68e-01 98.1% 82.5%
5077779 2003.1.5.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › BpsA_C 0.71 59.0 3.82e-01 98.1% 66.5%
3711349 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.70 59.0 3.60e-01 98.1% 39.8%
143936 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.69 56.0 3.81e-01 94.3% 59.0%
3963489 1.1.9.0 beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.69 60.0 4.37e-01 100.0% 49.3%
4241225 304.102.1.6 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruB_N,TruB_C_2 0.69 57.0 3.54e-01 96.2% 53.8%
3699728 878.1.1.0 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 0.68 56.0 4.40e-01 96.2% 77.5%
3599842 304.12.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.67 55.0 4.41e-01 94.3% 53.0%
3170700 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.66 56.0 3.42e-01 100.0% 80.8%
3509860 1.1.17.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.66 55.0 3.51e-01 94.3% 38.5%
5057186 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.65 54.0 4.70e-01 100.0% 65.6%
4934212 328.1.1.1 a+b two layers › IF3-like › AlbA-like › AlbA-like › Alba 0.65 52.0 4.46e-01 94.3% 93.7%
2407461 1.1.5.25 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.65 53.0 4.12e-01 98.1% 75.6%
3018445 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.64 52.0 3.49e-01 96.2% 64.8%
3923825 323.1.1.1 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.64 51.0 3.45e-01 96.2% 73.1%
2449257 1.1.9.0 beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.64 53.0 3.42e-01 100.0% 29.2%
3025136 218.2.1.1 a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.63 53.0 3.93e-01 100.0% 90.3%
4966689 2003.1.5.12 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase 0.63 54.0 3.28e-01 100.0% 34.5%
4976892 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 50.0 3.42e-01 90.6% 51.9%
3795831 1.1.13.0 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.63 53.0 4.96e-01 98.1% 89.7%
4994537 218.2.1.1 a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.63 51.0 3.70e-01 100.0% 75.0%
3990851 389.1.1.0 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin 0.63 50.0 4.86e-01 100.0% 80.0%
3501742 2485.3.1.21 a+b three layers › Thioredoxin-like › Major capsid protein gp5 › Major capsid protein gp5 › Phi29_MCP 0.63 52.0 3.34e-01 100.0% 73.5%
4189243 1.1.5.25 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.63 50.0 3.96e-01 96.2% 53.1%
3253396 868.1.1.2 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase 0.63 54.0 3.66e-01 100.0% 52.2%
4287081 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.63 50.0 4.01e-01 98.1% 80.8%
4670273 868.1.1.8 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › SLS1_C 0.62 52.0 3.44e-01 100.0% 49.6%
3995786 389.4.1.7 few secondary structure elements › EGF-like › Fibulin-4 EGF-like 1 domain › Fibulin-4 EGF-like 1 domain › TIL_2 0.62 50.0 4.82e-01 100.0% 78.5%
3602774 304.51.1.8 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6b_C 0.62 50.0 4.02e-01 94.3% 72.2%
3192615 868.1.1.8 a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › SLS1_C 0.62 51.0 3.23e-01 100.0% 51.9%
3943661 304.5.1.13 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF3574 0.61 48.0 4.06e-01 92.5% 66.0%
4640974 1.1.5.25 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.61 48.0 3.90e-01 96.2% 83.3%
5050618 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.61 51.0 3.91e-01 100.0% 61.4%
4632598 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 47.0 3.89e-01 98.1% 53.3%
3995923 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.60 46.0 3.05e-01 92.5% 61.3%
5000462 256.1.1.1 a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like › Archease 0.59 48.0 4.36e-01 100.0% 86.3%
5039496 101.1.2.914 alpha arrays › HTH › HTH › winged helix domain › DUF6015 0.59 47.0 3.96e-01 88.7% 95.6%
1312442 12.1.1.43 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Glyco_hydro_38 0.58 47.0 3.89e-01 100.0% 80.2%
1396465 12.1.1.43 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Glyco_hydro_38 0.58 47.0 3.81e-01 100.0% 82.4%
3934347 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 47.0 3.85e-01 100.0% 90.4%
3340998 323.1.1.1 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.57 44.0 3.03e-01 92.5% 70.6%
4997963 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.57 49.0 4.00e-01 100.0% 55.2%
5065450 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 46.0 3.39e-01 92.5% 55.5%
3353115 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 47.0 3.12e-01 100.0% 67.3%
3194998 4178.1.1.3 beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › DUF4140 0.56 43.0 3.41e-01 94.3% 66.7%
5038450 3435.1.1.0 a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC 0.56 40.0 2.70e-01 84.9% 35.2%
4965450 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.56 44.0 3.69e-01 98.1% 70.9%
3521712 109.6.1.1 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF 0.55 45.0 2.81e-01 96.2% 18.1%
5039316 304.102.1.2 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD 0.55 44.0 3.04e-01 94.3% 75.2%
3609057 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.55 42.0 3.31e-01 96.2% 60.7%
4016759 3385.1.1.0 beta barrels › Allergen Alt a 1 › Allergen Alt a 1 › Allergen Alt a 1 0.54 43.0 3.32e-01 94.3% 94.3%
4273561 1.1.7.91 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25940 0.54 43.0 3.40e-01 98.1% 58.5%
3988859 1.1.7.91 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25940 0.53 41.0 3.46e-01 92.5% 68.6%
3599732 213.1.1.0 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.53 44.0 2.94e-01 96.2% 80.7%
3473036 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 42.0 3.38e-01 100.0% 72.8%
3320569 207.1.1.29 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › Transp_inhibit 0.52 43.0 2.46e-01 90.6% 14.2%
4246955 218.2.1.1 a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.51 41.0 3.08e-01 96.2% 63.4%
4602130 218.2.1.1 a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.51 41.0 3.20e-01 98.1% 68.9%
4210343 218.2.1.1 a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22 0.51 40.0 3.38e-01 96.2% 93.6%
3742620 11.1.5.7 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Adap_comp_sub 0.50 38.0 3.09e-01 84.9% 53.9%
3927922 11.2.1.1 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.50 38.0 2.95e-01 90.6% 92.4%
D2 medium residues 54-112
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.74 49.0 4.39e-01 100.0% 48.2%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 57.0 4.89e-01 91.5% 54.8%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.72 49.0 4.69e-01 100.0% 61.8%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.71 52.0 4.74e-01 94.9% 58.7%
1yhuB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.68 61.0 4.49e-01 96.6% 68.1%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 51.0 4.55e-01 100.0% 58.8%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.65 50.0 4.55e-01 100.0% 62.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 56.0 5.20e-01 100.0% 84.4%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 52.0 4.32e-01 100.0% 50.0%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 40.0 4.03e-01 91.5% 62.3%
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.63 47.0 4.08e-01 94.9% 51.1%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.63 54.0 4.47e-01 100.0% 95.5%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.63 48.0 4.04e-01 100.0% 48.1%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.62 52.0 4.04e-01 100.0% 40.1%
5svlA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.62 53.0 5.12e-01 98.3% 86.8%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.62 43.0 4.03e-01 100.0% 57.9%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.61 51.0 4.97e-01 93.2% 97.0%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 51.0 4.80e-01 100.0% 78.4%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 46.0 4.30e-01 81.4% 65.8%
4ev6A03 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.61 51.0 5.16e-01 100.0% 94.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 51.0 4.33e-01 100.0% 55.4%
4ga0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 43.0 3.26e-01 74.6% 73.4%
2p1aB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.61 50.0 3.82e-01 93.2% 85.6%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.60 47.0 4.58e-01 88.1% 78.5%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.60 51.0 4.89e-01 100.0% 81.7%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.59 47.0 4.35e-01 94.9% 67.1%
3kbbA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.59 46.0 4.36e-01 84.7% 100.0%
3g3oA00 3.20.100.30 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › VTC, catalytic tunnel domain 0.58 41.0 2.69e-01 86.4% 15.7%
2k3oA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.57 47.0 3.82e-01 98.3% 77.5%
3j27B00 1.10.8.970 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Flavivirus envelope glycoprotein M-like 0.57 40.0 3.77e-01 81.4% 61.1%
1lkvX02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.57 44.0 3.56e-01 89.8% 60.6%
2hxiB02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 50.0 3.85e-01 100.0% 96.3%
3bg2A01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.56 47.0 3.28e-01 98.3% 28.6%
1w36F02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.55 45.0 3.79e-01 89.8% 96.0%
1m5yA01 1.10.4030.10 Mainly Alpha › Orthogonal Bundle › Triger factor/SurA peptide-binding fold › Porin chaperone SurA, peptide-binding domain 0.54 48.0 3.68e-01 94.9% 46.8%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.54 45.0 4.17e-01 96.6% 72.0%
2xzmV01 1.10.60.20 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 0.50 36.0 3.64e-01 100.0% 73.8%
3l8kA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 41.0 2.92e-01 100.0% 39.2%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4410658 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.71 53.0 3.15e-01 89.8% 11.3%
3775580 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.70 63.0 5.80e-01 100.0% 98.7%
3784716 109.4.1.602 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dor1 0.69 54.0 3.51e-01 100.0% 18.5%
3690687 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.69 55.0 5.08e-01 96.6% 69.3%
5050356 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.68 56.0 5.36e-01 93.2% 90.0%
3894917 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.68 58.0 4.61e-01 100.0% 47.5%
4329615 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.67 55.0 5.23e-01 100.0% 75.7%
3214359 568.1.1.0 few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related 0.67 48.0 5.11e-01 89.8% 90.0%
3780807 174.1.1.52 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 0.67 55.0 4.28e-01 100.0% 41.5%
3838316 3567.1.1.150 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › H-kinase_dim 0.66 57.0 5.26e-01 98.3% 74.7%
3462297 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.66 59.0 5.46e-01 100.0% 80.0%
3999040 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.66 59.0 4.23e-01 100.0% 35.3%
5019215 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.65 58.0 3.65e-01 100.0% 19.4%
3963155 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 55.0 5.11e-01 94.9% 77.3%
3530780 310.2.1.2 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › MIX23 0.65 57.0 4.42e-01 100.0% 46.2%
4017010 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.65 57.0 4.35e-01 100.0% 100.0%
3817153 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.65 57.0 4.74e-01 100.0% 56.2%
3386452 5050.1.1.21 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 0.64 56.0 4.25e-01 100.0% 64.8%
3652633 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.64 57.0 4.43e-01 100.0% 80.0%
3883670 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.64 57.0 4.51e-01 100.0% 61.7%
3231463 632.8.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C 0.64 56.0 4.81e-01 100.0% 92.6%
3386373 605.1.1.2 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim 0.64 56.0 5.42e-01 96.6% 89.2%
3581267 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 53.0 4.68e-01 100.0% 62.2%
3740232 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 52.0 3.97e-01 100.0% 38.6%
4944401 150.1.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.63 52.0 3.91e-01 94.9% 84.5%
4933825 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.63 56.0 4.71e-01 100.0% 70.0%
4133341 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.63 55.0 4.41e-01 100.0% 50.0%
143217 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 54.0 4.58e-01 100.0% 58.2%
3283686 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.62 48.0 4.62e-01 91.5% 74.3%
5059279 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.62 52.0 4.71e-01 98.3% 67.5%
3224580 3538.1.1.0 extended segments › MerF › MerF › MerF 0.61 50.0 5.01e-01 89.8% 90.0%
3286412 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.61 53.0 4.52e-01 100.0% 70.0%
3657573 109.4.1.1146 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.60 46.0 2.82e-01 84.7% 12.1%
4375453 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.60 50.0 4.72e-01 100.0% 76.0%
5053424 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.60 50.0 3.52e-01 91.5% 32.6%
3396401 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 49.0 4.02e-01 100.0% 50.4%
4179237 6028.1.1.0 alpha bundles › Ribosome modulation factor › Ribosome modulation factor › Ribosome modulation factor 0.57 49.0 4.76e-01 94.9% 84.6%
3240454 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 45.0 3.94e-01 100.0% 60.0%
5079025 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.54 40.0 3.87e-01 86.4% 68.6%
4964044 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.54 46.0 3.95e-01 100.0% 61.0%
3602030 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.53 47.0 4.03e-01 98.3% 61.1%