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MK203850.3__AZS06564.1__X__00014

Bact-Vir

MK203850.3__AZS06564.1__X__00014

Identity

Accession:
MK203850 ↗
Kingdom:
phage

Quality

83.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 121-224
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.75 53.0 4.55e-01 73.1% 52.2%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.73 52.0 4.25e-01 100.0% 39.8%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 52.0 3.82e-01 74.0% 88.0%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.71 49.0 3.83e-01 72.1% 35.2%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.69 55.0 4.17e-01 84.6% 69.4%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 62.0 4.58e-01 100.0% 47.4%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.68 52.0 3.72e-01 82.7% 32.4%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 39.0 3.04e-01 85.6% 30.3%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.68 48.0 3.42e-01 73.1% 87.7%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 56.0 4.07e-01 88.5% 66.4%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 58.0 4.56e-01 99.0% 62.7%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 54.0 4.38e-01 100.0% 63.7%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 35.0 3.23e-01 88.5% 43.8%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 40.0 3.82e-01 71.2% 59.2%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3560229 3291.1.1.230 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH 0.78 55.0 4.95e-01 73.1% 64.3%
3862009 3755.3.1.293 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH 0.75 54.0 4.58e-01 73.1% 57.5%
3534501 3755.3.1.293 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH 0.75 53.0 4.66e-01 73.1% 60.0%
3730423 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.71 51.0 3.54e-01 73.1% 69.4%
3697355 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 51.0 4.48e-01 99.0% 50.3%
3718629 3755.2.1.0 alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein 0.70 49.0 3.69e-01 73.1% 36.5%
3656716 3755.3.1.498 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF31016 0.70 50.0 4.54e-01 76.0% 74.5%
3867942 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.69 49.0 3.78e-01 74.0% 32.8%
3437287 5086.1.1.199 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF31016 0.68 53.0 4.43e-01 82.7% 77.7%
5009131 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 52.0 4.38e-01 98.1% 50.3%
3304001 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.67 40.0 3.60e-01 85.6% 42.9%
3264876 604.12.1.42 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF202 0.67 38.0 3.89e-01 82.7% 57.0%
3358852 3755.4.1.62 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF31016 0.67 51.0 4.53e-01 82.7% 87.1%
3875112 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 53.0 3.62e-01 86.5% 50.6%
3699903 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.63 37.0 3.82e-01 84.6% 60.0%
3259375 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.61 53.0 4.83e-01 93.3% 95.6%
3650747 626.1.1.1 alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › FH2 0.57 50.0 3.43e-01 100.0% 68.1%
3189791 601.19.1.18 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C 0.55 48.0 3.73e-01 100.0% 43.9%
3724992 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.54 49.0 3.59e-01 98.1% 81.9%
3275656 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.54 48.0 4.26e-01 100.0% 76.7%
D2 medium residues 225-291
PDB
Domain cluster: representative
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.87 59.0 6.88e-01 79.1% 95.9%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.84 66.0 6.76e-01 82.1% 95.3%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.83 77.0 6.30e-01 100.0% 85.3%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 65.0 6.14e-01 82.1% 79.2%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.81 63.0 3.97e-01 82.1% 68.3%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.80 62.0 5.12e-01 80.6% 55.5%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 56.0 5.97e-01 83.6% 84.7%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.79 59.0 4.88e-01 79.1% 46.5%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.78 60.0 6.20e-01 82.1% 89.1%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.78 59.0 4.53e-01 80.6% 93.1%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 60.0 3.94e-01 82.1% 22.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.78 70.0 6.12e-01 100.0% 93.9%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 70.0 4.97e-01 98.5% 40.3%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 69.0 5.72e-01 100.0% 80.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 70.0 6.20e-01 97.0% 96.7%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 54.0 5.73e-01 74.6% 98.3%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 68.0 5.54e-01 100.0% 82.8%
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 55.0 5.75e-01 76.1% 91.8%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 57.0 3.75e-01 80.6% 39.3%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 66.0 5.95e-01 100.0% 93.6%
3i01A01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.74 57.0 4.14e-01 82.1% 48.6%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 65.0 5.61e-01 100.0% 92.6%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.74 56.0 5.82e-01 79.1% 93.4%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 65.0 5.57e-01 100.0% 80.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.74 66.0 5.47e-01 100.0% 92.3%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 65.0 5.66e-01 98.5% 95.0%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 56.0 5.51e-01 80.6% 90.1%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.74 65.0 5.45e-01 97.0% 90.1%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.74 65.0 5.56e-01 100.0% 95.5%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.73 64.0 5.37e-01 100.0% 84.0%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 65.0 5.41e-01 100.0% 77.1%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.73 65.0 5.90e-01 100.0% 85.7%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 56.0 4.89e-01 83.6% 96.1%
1mhyG01 1.20.1280.10 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 1 0.73 59.0 5.91e-01 89.6% 89.7%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 65.0 4.89e-01 100.0% 46.9%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 64.0 5.29e-01 100.0% 87.5%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 54.0 3.95e-01 82.1% 30.0%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.72 64.0 5.95e-01 100.0% 89.4%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.72 67.0 4.90e-01 98.5% 59.6%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.72 55.0 4.12e-01 82.1% 35.0%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.72 53.0 4.27e-01 83.6% 41.4%
3n98A01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.71 57.0 3.51e-01 88.1% 22.8%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.71 55.0 5.34e-01 83.6% 77.6%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.71 52.0 5.00e-01 80.6% 68.4%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 62.0 4.87e-01 97.0% 54.7%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.71 62.0 5.79e-01 100.0% 92.9%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 61.0 5.23e-01 100.0% 92.9%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.70 54.0 4.83e-01 83.6% 61.1%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.70 59.0 4.51e-01 92.5% 73.3%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.69 64.0 4.73e-01 98.5% 64.6%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 57.0 5.34e-01 92.5% 92.9%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.69 61.0 5.93e-01 100.0% 100.0%
5c9eB01 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.69 55.0 4.99e-01 85.1% 77.0%
3u4qA02 1.10.274.50 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › 0.69 58.0 4.44e-01 92.5% 53.3%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.69 51.0 5.22e-01 79.1% 90.8%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 62.0 4.94e-01 100.0% 67.7%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.68 61.0 4.56e-01 97.0% 56.4%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.68 51.0 5.03e-01 83.6% 75.3%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 59.0 5.03e-01 100.0% 86.8%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 58.0 5.06e-01 98.5% 90.6%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 49.0 3.95e-01 76.1% 42.1%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 58.0 3.81e-01 100.0% 35.0%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 56.0 4.89e-01 92.5% 85.1%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 58.0 4.82e-01 100.0% 84.2%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.65 55.0 4.71e-01 91.0% 69.5%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.65 52.0 5.21e-01 88.1% 100.0%
2osaA00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.64 56.0 4.00e-01 98.5% 75.5%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.63 51.0 3.17e-01 91.0% 23.5%
5k29A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.61 54.0 4.80e-01 100.0% 76.3%
7zd5C01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.60 50.0 3.28e-01 97.0% 87.7%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.59 48.0 4.31e-01 95.5% 62.6%
1o3uA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.55 51.0 4.11e-01 100.0% 82.5%
2mjfB00 1.20.1440.260 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.55 42.0 3.70e-01 80.6% 87.4%
2lfhA00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.53 35.0 3.48e-01 100.0% 66.2%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3788539 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 67.0 3.99e-01 82.1% 14.2%
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.85 66.0 5.11e-01 82.1% 47.4%
3476064 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.83 65.0 5.24e-01 82.1% 47.5%
3701816 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 77.0 6.17e-01 100.0% 87.5%
3178900 192.2.1.30 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Uds1 0.82 64.0 4.85e-01 82.1% 46.2%
3739377 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.82 63.0 4.04e-01 82.1% 21.7%
3221764 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.82 76.0 7.09e-01 100.0% 91.3%
4587769 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.82 62.0 6.31e-01 79.1% 95.4%
4463205 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.81 64.0 3.74e-01 82.1% 11.9%
3596258 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 64.0 4.15e-01 82.1% 27.8%
3577907 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.81 62.0 4.06e-01 80.6% 22.4%
3737161 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.81 63.0 5.27e-01 82.1% 51.8%
3929613 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.81 63.0 3.97e-01 82.1% 20.0%
4459896 622.4.1.1 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 0.81 75.0 6.14e-01 100.0% 86.0%
5018554 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.81 61.0 5.23e-01 82.1% 53.0%
3649758 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 63.0 4.21e-01 82.1% 25.3%
4192699 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.80 61.0 4.84e-01 80.6% 46.9%
3368195 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 73.0 5.48e-01 100.0% 46.5%
3558280 603.1.1.114 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HR1 0.80 62.0 5.42e-01 82.1% 67.4%
4433231 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.79 65.0 4.63e-01 88.1% 70.3%
3477880 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.79 61.0 3.91e-01 82.1% 21.0%
4946898 375.1.9.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase 0.79 61.0 5.86e-01 82.1% 76.0%
3961148 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 59.0 4.86e-01 80.6% 45.0%
3598168 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.78 59.0 4.36e-01 82.1% 32.7%
3565220 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.78 59.0 4.60e-01 82.1% 40.7%
2122584 109.26.1.1 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.78 71.0 4.11e-01 100.0% 15.9%
3748303 174.1.1.52 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 0.77 71.0 5.37e-01 100.0% 66.0%
3322575 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.77 59.0 3.82e-01 80.6% 20.4%
3944731 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 58.0 4.34e-01 80.6% 80.0%
3802509 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.77 57.0 4.30e-01 79.1% 34.7%
3884473 150.3.1.10 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › CNTF 0.77 66.0 4.81e-01 94.0% 70.3%
5022672 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.76 58.0 5.19e-01 82.1% 60.0%
4213065 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.76 70.0 5.21e-01 100.0% 72.5%
4014485 5044.1.1.0 extended segments › PsbZ-like › PsbZ-like › PsbZ-like 0.76 59.0 5.19e-01 82.1% 81.1%
3179076 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.76 69.0 5.51e-01 100.0% 99.2%
3497645 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.76 68.0 6.42e-01 100.0% 97.5%
3381762 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.76 69.0 4.38e-01 100.0% 36.1%
3192001 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.75 67.0 5.26e-01 100.0% 80.7%
4954038 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.75 57.0 3.65e-01 82.1% 17.7%
4468389 5086.1.1.101 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.75 56.0 4.60e-01 80.6% 45.0%
3832250 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.74 57.0 4.49e-01 82.1% 45.2%
3276733 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.74 68.0 5.15e-01 100.0% 62.0%
4549103 3755.4.1.54 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 0.74 56.0 3.44e-01 80.6% 25.3%
3854672 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.74 64.0 4.37e-01 92.5% 61.4%
3619662 192.12.1.3 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › DUF747 0.74 56.0 5.30e-01 80.6% 75.0%
3871897 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.74 63.0 4.36e-01 92.5% 64.3%
4420750 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.74 57.0 5.63e-01 82.1% 87.1%
4563674 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.74 57.0 5.61e-01 82.1% 87.1%
4978274 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.74 64.0 5.30e-01 95.5% 67.8%
3645542 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.73 67.0 5.24e-01 100.0% 82.2%
3484930 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 64.0 5.55e-01 100.0% 94.3%
3504301 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 65.0 5.48e-01 100.0% 91.8%
3482686 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 62.0 5.71e-01 100.0% 97.8%
1002194 192.23.1.1 alpha bundles › Long alpha-hairpin › DUF683 › DUF683 › Rop-like 0.72 54.0 5.32e-01 80.6% 84.5%
3437243 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.71 54.0 4.30e-01 82.1% 44.4%
3627463 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 63.0 3.52e-01 100.0% 10.2%
3227678 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.70 53.0 4.69e-01 82.1% 58.0%
3721147 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 62.0 4.73e-01 100.0% 56.2%
3716819 109.4.1.32 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G 0.70 57.0 3.56e-01 86.6% 29.1%
3556900 3758.1.1.66 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › TMEM120A-B 0.70 63.0 4.30e-01 100.0% 73.2%
5079439 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 63.0 5.34e-01 97.0% 68.6%
3699313 6155.1.1.4 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC 0.69 61.0 5.57e-01 100.0% 85.6%
4018370 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.69 63.0 5.00e-01 100.0% 93.1%
3262164 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.69 59.0 4.03e-01 100.0% 39.6%
3845184 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.68 62.0 4.38e-01 98.5% 57.9%
4195230 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 58.0 4.78e-01 95.5% 94.2%
4399455 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.66 56.0 4.42e-01 100.0% 67.7%
3688832 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 57.0 4.22e-01 100.0% 46.3%
3680604 246.3.1.17 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › PF27823 0.66 48.0 3.16e-01 77.6% 31.2%
3225965 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 46.0 3.44e-01 73.1% 81.8%
3189488 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.65 56.0 4.85e-01 100.0% 72.7%
3912386 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.65 55.0 3.96e-01 97.0% 67.8%
3610706 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.65 50.0 4.77e-01 85.1% 78.8%
3679395 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.65 57.0 3.96e-01 100.0% 87.1%
3932692 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.64 53.0 4.89e-01 95.5% 94.4%
3860575 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.60 52.0 3.74e-01 100.0% 50.2%
D3 medium residues 567-679
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e6oA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.70 40.0 4.53e-01 82.3% 73.6%
1gccA00 3.30.730.10 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain 0.70 24.0 3.23e-01 78.8% 54.0%
3hi7B02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 48.0 4.64e-01 77.9% 69.5%
6grrA03 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 42.0 4.32e-01 73.5% 82.1%
2ltuA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.56 30.0 3.86e-01 85.0% 93.5%
3zxkA02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 41.0 3.33e-01 80.5% 87.0%
3by8A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.53 37.0 3.53e-01 71.7% 100.0%
4d47A00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 41.0 2.82e-01 84.1% 30.7%
4fwwA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 44.0 2.97e-01 95.6% 41.8%
3vz9B00 3.30.457.50 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Chromosome segregation protein Spc25 0.52 28.0 2.98e-01 72.6% 56.3%
3q0xA01 2.170.210.20 Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › Spindle assembly abnormal protein 6, N-terminal domain 0.51 42.0 3.79e-01 88.5% 92.3%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3389940 708.1.1.4 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › FLYWCH 0.60 31.0 3.45e-01 83.2% 61.1%
5009569 243.5.1.2 a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region › Cu_amine_oxidN3 0.58 41.0 4.06e-01 73.5% 75.0%
3449001 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.57 44.0 3.19e-01 83.2% 30.6%
3715861 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.56 42.0 2.78e-01 80.5% 50.9%
5015761 223.1.1.157 a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_3_3 0.54 39.0 2.92e-01 76.1% 82.3%
4189433 223.1.1.81 a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK 0.54 40.0 3.37e-01 77.9% 74.0%
3431347 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.53 38.0 2.95e-01 74.3% 50.2%
3188229 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 42.0 2.79e-01 84.1% 66.9%
3278065 4312.1.1.4 a+b two layers › RelE-like › RelE-like › RelE-like › Gp49 0.52 36.0 3.65e-01 73.5% 71.8%
3682458 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.50 42.0 2.94e-01 92.0% 42.4%