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MK249871.1__AZU97809.1__X__00004
Bact-VirMK249871.1__AZU97809.1__X__00004
Identity
- Accession:
- MK249871 ↗
- Kingdom:
- phage
Quality
77.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-74
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4c2mA04 | 3.30.1490.180 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase ii | 0.62 | 46.0 | 4.55e-01 | 79.7% | 97.4% |
| 2p84A02 | 2.30.30.290 | Mainly Beta › Roll › SH3 type barrels. › YopX-like domains | 0.59 | 41.0 | 4.20e-01 | 73.0% | 82.2% |
| 1twfA04 | 3.30.1490.180 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase ii | 0.58 | 43.0 | 4.56e-01 | 81.1% | 98.4% |
| 1sb7A02 | 3.30.2340.10 | Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › TruD, insertion domain | 0.58 | 47.0 | 3.95e-01 | 93.2% | 61.0% |
| 4g6iC02 | 2.40.30.20 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.57 | 44.0 | 4.13e-01 | 85.1% | 98.9% |
| 2oseA00 | 2.40.100.10 | Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like | 0.57 | 42.0 | 3.13e-01 | 79.7% | 61.5% |
| 3pm9A02 | 3.30.465.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › | 0.54 | 44.0 | 3.84e-01 | 91.9% | 63.9% |
| 1mgpA01 | 3.40.50.10170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 39.0 | 3.11e-01 | 75.7% | 71.0% |
| 1zr6A02 | 3.30.465.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › | 0.53 | 47.0 | 3.85e-01 | 100.0% | 81.6% |
| 2m1mA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 39.0 | 3.54e-01 | 79.7% | 78.5% |
| 2bn4B03 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.53 | 41.0 | 3.30e-01 | 86.5% | 90.5% |
| 2v3mA00 | 2.40.10.230 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain | 0.53 | 37.0 | 3.42e-01 | 73.0% | 86.2% |
| 3ke6B01 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.52 | 43.0 | 3.14e-01 | 93.2% | 97.7% |
| 4chkB00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 39.0 | 3.74e-01 | 82.4% | 87.9% |
| 1wmhA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 39.0 | 3.79e-01 | 82.4% | 96.4% |
| 5ovpA00 | 2.30.42.10 | Mainly Beta › Roll › Pdz3 Domain › PDZ domain | 0.51 | 38.0 | 3.57e-01 | 82.4% | 100.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5058903 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.64 | 52.0 | 3.87e-01 | 89.2% | 72.6% |
| 3417262 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.63 | 47.0 | 4.77e-01 | 81.1% | 94.7% |
| 5054580 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.63 | 48.0 | 5.08e-01 | 82.4% | 96.9% |
| 3618553 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.63 | 47.0 | 4.71e-01 | 81.1% | 98.7% |
| 4015760 | 1.1.2.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi | 0.61 | 49.0 | 3.66e-01 | 89.2% | 72.8% |
| 2700171 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.60 | 45.0 | 4.34e-01 | 79.7% | 100.0% |
| 3733629 | 4951.1.1.1 ↗ | alpha arrays › inserted helical subdomain in bacterial RNA-polymerase beta-prime subunit › inserted helical subdomain in bacterial RNA-polymerase beta-prime subunit › inserted helical subdomain in bacterial RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2 | 0.60 | 44.0 | 4.65e-01 | 79.7% | 93.8% |
| 4803227 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.58 | 43.0 | 4.56e-01 | 79.7% | 100.0% |
| 3556111 | 275.1.1.1 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › RNA_pol_Rpb1_2 | 0.57 | 43.0 | 4.51e-01 | 81.1% | 95.4% |
| 3686789 | 217.1.1.2 ↗ | a+b complex topology › FAD-binding domain-like › FAD-binding domain › FAD-binding domain › FAD_binding_4 | 0.57 | 46.0 | 3.35e-01 | 89.2% | 80.9% |
| 3784216 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.56 | 48.0 | 4.19e-01 | 100.0% | 85.8% |
| 3690276 | 2003.1.5.73 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 | 0.55 | 46.0 | 3.04e-01 | 95.9% | 68.8% |
| 5026975 | 1056.1.1.1 ↗ | a+b two layers › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain › TruD | 0.54 | 45.0 | 3.30e-01 | 94.6% | 87.6% |
| 4105184 | 221.1.4.3 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Nqo1 middle domain-like › SLBB_2 | 0.53 | 42.0 | 3.84e-01 | 87.8% | 73.0% |
| 4950662 | 1056.1.1.1 ↗ | a+b two layers › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain › tRNA pseudouridine synthase TruD insertion domain › TruD | 0.53 | 45.0 | 3.32e-01 | 97.3% | 89.5% |
| 1887268 | 75.1.1.1 ↗ | beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase | 0.53 | 44.0 | 3.60e-01 | 95.9% | 92.0% |
| 3945554 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.52 | 42.0 | 3.94e-01 | 91.9% | 81.1% |
| 5009755 | 4176.1.1.2 ↗ | a/b three-layered sandwiches › a/b domain in CV3147-like proteins › a/b domain in CV3147-like proteins › a/b domain in CV3147-like proteins › S-Me-THD_N | 0.52 | 44.0 | 3.26e-01 | 100.0% | 48.4% |
| 3791385 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 37.0 | 3.24e-01 | 82.4% | 60.0% |
D2
high
residues 84-125
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.91 | 78.0 | 7.21e-01 | 92.9% | 80.8% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.91 | 83.0 | 6.67e-01 | 100.0% | 60.5% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.90 | 81.0 | 5.46e-01 | 100.0% | 31.0% |
| 2jdiG01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.88 | 77.0 | 6.83e-01 | 100.0% | 75.4% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 77.0 | 5.28e-01 | 100.0% | 31.9% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 78.0 | 5.00e-01 | 100.0% | 24.1% |
| 4hb1A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.87 | 77.0 | 7.64e-01 | 100.0% | 95.5% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 78.0 | 5.26e-01 | 100.0% | 29.2% |
| 3rkoF01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.87 | 77.0 | 5.10e-01 | 100.0% | 26.2% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.86 | 75.0 | 7.23e-01 | 100.0% | 87.5% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.85 | 75.0 | 5.60e-01 | 100.0% | 44.1% |
| 2i9cA01 | 1.25.40.70 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) | 0.85 | 74.0 | 5.45e-01 | 100.0% | 40.5% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.85 | 69.0 | 5.85e-01 | 100.0% | 54.9% |
| 1om2A00 | 1.20.960.10 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › Mitochondrial outer membrane translocase complex, subunit Tom20 domain | 0.85 | 69.0 | 5.24e-01 | 90.5% | 43.2% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 72.0 | 6.44e-01 | 100.0% | 85.5% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.84 | 74.0 | 6.13e-01 | 100.0% | 58.1% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.83 | 71.0 | 6.75e-01 | 100.0% | 88.2% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 73.0 | 6.23e-01 | 100.0% | 63.2% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 68.0 | 5.55e-01 | 100.0% | 49.4% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.82 | 70.0 | 6.09e-01 | 100.0% | 67.2% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.82 | 65.0 | 6.42e-01 | 90.5% | 100.0% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.82 | 69.0 | 5.80e-01 | 100.0% | 56.0% |
| 2a26B01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.81 | 67.0 | 6.66e-01 | 97.6% | 93.2% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.80 | 66.0 | 5.84e-01 | 100.0% | 100.0% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.80 | 66.0 | 5.34e-01 | 97.6% | 69.4% |
| 2qtfA02 | 6.10.250.2860 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.80 | 67.0 | 6.58e-01 | 100.0% | 89.4% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.79 | 65.0 | 5.56e-01 | 100.0% | 58.1% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.76 | 65.0 | 5.20e-01 | 100.0% | 50.6% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.74 | 60.0 | 4.52e-01 | 100.0% | 36.8% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.72 | 60.0 | 4.93e-01 | 97.6% | 49.4% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.70 | 56.0 | 4.17e-01 | 100.0% | 32.8% |
| 3k59A06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.70 | 53.0 | 5.24e-01 | 100.0% | 83.0% |
| 1gs0A01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.69 | 60.0 | 4.25e-01 | 100.0% | 73.6% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 54.0 | 4.62e-01 | 100.0% | 51.9% |
| 1gcvB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.66 | 49.0 | 3.47e-01 | 81.0% | 59.6% |
| 3bg2A02 | 1.10.3550.10 | Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › eoxyguanosinetriphosphate triphosphohydrolase domain-like | 0.66 | 56.0 | 4.16e-01 | 100.0% | 50.0% |
| 2h09A02 | 1.10.60.10 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain | 0.66 | 49.0 | 4.47e-01 | 83.3% | 60.7% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.66 | 54.0 | 3.52e-01 | 90.5% | 22.7% |
| 3tdvA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.63 | 49.0 | 3.34e-01 | 100.0% | 20.4% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 53.0 | 4.48e-01 | 100.0% | 62.7% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 49.0 | 4.55e-01 | 100.0% | 75.9% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3818994 | 109.4.1.509 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT | 0.94 | 87.0 | 4.74e-01 | 100.0% | 8.1% |
| 5043119 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.92 | 85.0 | 7.00e-01 | 100.0% | 60.0% |
| 4017163 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.92 | 77.0 | 4.95e-01 | 100.0% | 22.4% |
| 5078048 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.91 | 83.0 | 6.74e-01 | 100.0% | 62.7% |
| 4032991 | 6072.1.1.0 ↗ | alpha arrays › Transmembrane domain of envelope protein E › Transmembrane domain of envelope protein E › Transmembrane domain of envelope protein E | 0.91 | 82.0 | 6.17e-01 | 100.0% | 45.3% |
| 3482166 | 5039.1.1.0 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like | 0.91 | 80.0 | 5.31e-01 | 100.0% | 26.4% |
| 3409452 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.90 | 80.0 | 6.27e-01 | 100.0% | 52.9% |
| 5055477 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.89 | 80.0 | 6.37e-01 | 100.0% | 52.5% |
| 4977808 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.89 | 79.0 | 6.64e-01 | 100.0% | 60.0% |
| 4993041 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.88 | 78.0 | 6.25e-01 | 100.0% | 56.2% |
| 5054531 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.88 | 75.0 | 5.57e-01 | 95.2% | 40.0% |
| 4778768 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.87 | 77.0 | 7.64e-01 | 100.0% | 95.5% |
| 3425962 | 603.1.1.116 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27980 | 0.86 | 74.0 | 5.92e-01 | 100.0% | 65.9% |
| 3174647 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.84 | 73.0 | 6.21e-01 | 100.0% | 60.0% |
| 3568826 | 5020.1.1.13 ↗ | extended segments › Subunit VIII of photosystem I reaction centre, PsaI › Subunit VIII of photosystem I reaction centre, PsaI › Subunit VIII of photosystem I reaction centre, PsaI › TMEM219 | 0.84 | 76.0 | 6.49e-01 | 100.0% | 64.6% |
| 3253483 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.84 | 71.0 | 6.11e-01 | 100.0% | 100.0% |
| 3487704 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.83 | 73.0 | 5.26e-01 | 100.0% | 37.4% |
| 4129936 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.83 | 70.0 | 5.45e-01 | 100.0% | 44.2% |
| 4959934 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.82 | 67.0 | 5.58e-01 | 100.0% | 52.0% |
| 3281357 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.82 | 73.0 | 4.90e-01 | 100.0% | 30.3% |
| 3163939 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.81 | 68.0 | 6.56e-01 | 100.0% | 84.0% |
| 4408580 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.81 | 68.0 | 6.74e-01 | 100.0% | 93.3% |
| 4927596 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 66.0 | 4.79e-01 | 100.0% | 36.2% |
| 3731062 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.79 | 66.0 | 5.38e-01 | 100.0% | 49.4% |
| 1556809 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.79 | 65.0 | 5.68e-01 | 100.0% | 62.3% |
| 3591396 | 3866.1.1.0 ↗ | extended segments › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 | 0.78 | 64.0 | 5.08e-01 | 100.0% | 44.2% |
| 3973900 | 192.8.1.331 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF4824 | 0.77 | 63.0 | 5.21e-01 | 100.0% | 50.6% |
| 3338292 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.77 | 63.0 | 4.58e-01 | 100.0% | 41.5% |
| 1095885 | 6128.1.1.0 ↗ | 0.74 | 61.0 | 5.51e-01 | 100.0% | 79.4% | |
| 3576223 | 604.33.1.1 ↗ | alpha bundles › Spectrin repeat-like › Repulsive guidance molecule (RGM) N-terminal domain › Repulsive guidance molecule (RGM) N-terminal domain › RGM_N | 0.72 | 57.0 | 4.92e-01 | 95.2% | 59.5% |
| 3388176 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.70 | 55.0 | 4.29e-01 | 100.0% | 37.3% |
| 3963155 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 52.0 | 4.58e-01 | 95.2% | 80.0% |
| 4012828 | 196.1.1.0 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS | 0.68 | 54.0 | 3.70e-01 | 100.0% | 23.8% |
| 3497466 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.62 | 51.0 | 4.16e-01 | 100.0% | 46.7% |
| 3296047 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.62 | 52.0 | 4.19e-01 | 97.6% | 50.6% |
D3
high
residues 134-192
Domain cluster:
rep: OX241575.1__CAH9016878.1__VP120E341_P0092__00092__D86-141
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5zctA02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.62 | 53.0 | 5.13e-01 | 100.0% | 100.0% |
| 1pqsA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.61 | 50.0 | 4.72e-01 | 100.0% | 100.0% |
| 3kq5A01 | 1.10.3210.40 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › | 0.60 | 49.0 | 3.44e-01 | 96.6% | 65.6% |
| 1ip9A00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.60 | 49.0 | 4.49e-01 | 100.0% | 78.8% |
| 1qfjA01 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.59 | 51.0 | 4.46e-01 | 98.3% | 93.4% |
| 2e0nB02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.58 | 49.0 | 4.10e-01 | 100.0% | 88.4% |
| 1wmhA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.58 | 46.0 | 4.23e-01 | 94.9% | 94.0% |
| 2c00A03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.57 | 48.0 | 4.65e-01 | 98.3% | 98.5% |
| 1cbfA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.57 | 48.0 | 3.92e-01 | 100.0% | 82.6% |
| 5ig0A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 46.0 | 3.65e-01 | 94.9% | 75.6% |
| 2c60A01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 45.0 | 4.28e-01 | 100.0% | 89.9% |
| 2bkfA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 45.0 | 4.21e-01 | 100.0% | 86.7% |
| 5t17A00 | 3.30.1340.10 | Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › HPr-like | 0.56 | 44.0 | 4.13e-01 | 100.0% | 78.8% |
| 1a9xA07 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.55 | 42.0 | 4.28e-01 | 98.3% | 94.5% |
| 1vkzA02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.55 | 45.0 | 4.36e-01 | 98.3% | 100.0% |
| 4izoA02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.55 | 43.0 | 4.27e-01 | 98.3% | 89.6% |
| 1auvA01 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.54 | 43.0 | 4.38e-01 | 98.3% | 100.0% |
| 6melB02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.54 | 42.0 | 3.90e-01 | 94.9% | 94.0% |
| 3q90B00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.54 | 43.0 | 3.49e-01 | 94.9% | 72.3% |
| 4j2gA00 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.53 | 39.0 | 2.80e-01 | 83.1% | 88.1% |
| 1wi0A00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 42.0 | 3.56e-01 | 94.9% | 77.9% |
| 5i47B02 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.53 | 42.0 | 4.16e-01 | 98.3% | 97.0% |
| 3glkA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.52 | 41.0 | 4.12e-01 | 91.5% | 96.6% |
| 1oeyL00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 42.0 | 3.72e-01 | 100.0% | 82.7% |
| 3tiiA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.51 | 41.0 | 4.01e-01 | 94.9% | 100.0% |
| 1vhvA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.51 | 41.0 | 3.30e-01 | 100.0% | 51.1% |
ECOD (48)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3647111 | 7577.1.1.0 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases | 0.66 | 57.0 | 3.14e-01 | 100.0% | 5.8% |
| 3256148 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.66 | 54.0 | 5.06e-01 | 94.9% | 100.0% |
| 3380716 | 2003.1.5.46 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS | 0.64 | 56.0 | 3.50e-01 | 100.0% | 18.1% |
| 3828738 | 243.1.1.2 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 | 0.62 | 48.0 | 3.62e-01 | 88.1% | 72.3% |
| 3942306 | 206.1.3.21 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK | 0.62 | 51.0 | 3.65e-01 | 100.0% | 79.5% |
| 3593442 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.61 | 51.0 | 4.39e-01 | 100.0% | 64.8% |
| 4240302 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.61 | 51.0 | 3.28e-01 | 100.0% | 76.1% |
| 4928538 | 2003.1.5.42 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21 | 0.61 | 50.0 | 3.57e-01 | 100.0% | 83.2% |
| 432311 | 304.22.1.1 ↗ | a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain › UreE_C | 0.60 | 41.0 | 3.71e-01 | 100.0% | 52.5% |
| 4205235 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.59 | 49.0 | 3.23e-01 | 100.0% | 28.7% |
| 5079552 | 2005.1.1.2 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1b | 0.59 | 51.0 | 3.15e-01 | 100.0% | 21.0% |
| 3233435 | 7.1.1.0 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain | 0.59 | 49.0 | 4.47e-01 | 100.0% | 97.6% |
| 4985499 | 206.1.3.21 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RimK | 0.59 | 49.0 | 3.51e-01 | 100.0% | 76.0% |
| 5022617 | 1137.1.1.0 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain | 0.59 | 50.0 | 4.28e-01 | 100.0% | 64.0% |
| 3594867 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.59 | 47.0 | 3.41e-01 | 98.3% | 72.9% |
| 4048953 | 206.1.3.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp | 0.59 | 48.0 | 3.41e-01 | 100.0% | 75.3% |
| 1936911 | 1137.1.1.0 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain | 0.58 | 49.0 | 4.09e-01 | 100.0% | 88.4% |
| 3236388 | 10.4.1.0 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain | 0.58 | 50.0 | 4.25e-01 | 100.0% | 73.0% |
| 3610692 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.58 | 48.0 | 4.08e-01 | 98.3% | 71.4% |
| 5018654 | 304.117.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC | 0.58 | 47.0 | 4.55e-01 | 100.0% | 80.0% |
| 4942475 | 4261.1.1.0 ↗ | a+b two layers › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA C-terminal domain-like | 0.57 | 47.0 | 4.47e-01 | 100.0% | 82.7% |
| 3239028 | 206.1.3.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › Synapsin_C | 0.56 | 46.0 | 3.32e-01 | 98.3% | 31.7% |
| 3630686 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.56 | 46.0 | 2.90e-01 | 100.0% | 52.6% |
| 3550624 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.56 | 45.0 | 3.85e-01 | 96.6% | 95.5% |
| 3829832 | 243.1.1.2 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 | 0.56 | 45.0 | 3.78e-01 | 93.2% | 90.0% |
| 4680848 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.56 | 46.0 | 3.10e-01 | 100.0% | 53.3% |
| 3187872 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.55 | 44.0 | 3.93e-01 | 94.9% | 89.4% |
| 4948526 | 206.1.3.8 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_3 | 0.55 | 45.0 | 2.91e-01 | 100.0% | 46.9% |
| 3881127 | 10.12.1.9 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC | 0.55 | 45.0 | 2.85e-01 | 100.0% | 39.0% |
| 3463416 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.55 | 45.0 | 3.34e-01 | 100.0% | 37.8% |
| 3490042 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.55 | 44.0 | 3.91e-01 | 100.0% | 86.0% |
| 3741775 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.54 | 45.0 | 4.21e-01 | 96.6% | 84.0% |
| 3810513 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.54 | 43.0 | 3.62e-01 | 100.0% | 73.6% |
| 3232920 | 10.4.1.0 ↗ | beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain | 0.54 | 44.0 | 3.94e-01 | 100.0% | 100.0% |
| 3440710 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.54 | 44.0 | 3.88e-01 | 100.0% | 88.0% |
| 3239822 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.54 | 44.0 | 3.58e-01 | 100.0% | 71.5% |
| 3396364 | 206.1.3.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL | 0.53 | 43.0 | 2.74e-01 | 100.0% | 53.0% |
| 4017638 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.53 | 43.0 | 3.65e-01 | 96.6% | 85.5% |
| 3637847 | 243.1.1.2 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 | 0.53 | 41.0 | 3.72e-01 | 91.5% | 77.8% |
| 3350942 | 387.1.1.0 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › omega toxin-related | 0.53 | 36.0 | 2.29e-01 | 100.0% | 12.5% |
| 3201224 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.52 | 42.0 | 3.68e-01 | 100.0% | 85.4% |
| 3312072 | 304.6.1.2 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › ALO | 0.52 | 36.0 | 2.36e-01 | 100.0% | 14.3% |
| 3644383 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.52 | 42.0 | 3.71e-01 | 100.0% | 93.0% |
| 3619962 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.52 | 42.0 | 3.85e-01 | 100.0% | 85.9% |
| 3595603 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.51 | 40.0 | 3.82e-01 | 100.0% | 81.2% |
| 3807153 | 221.1.1.88 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › CLU_N | 0.50 | 40.0 | 3.59e-01 | 100.0% | 69.0% |
| 3597362 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 41.0 | 3.42e-01 | 96.6% | 90.4% |
| 3592225 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 41.0 | 3.78e-01 | 100.0% | 83.5% |
D4
high
residues 195-245
Domain cluster:
representative
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.70 | 52.0 | 4.16e-01 | 80.4% | 41.7% |
| 3gzfD00 | 1.10.150.420 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Coronavirus nonstructural protein 4 C-terminus | 0.69 | 45.0 | 3.72e-01 | 78.4% | 37.4% |
| 3pmiA02 | 6.10.300.20 | Special › Helix non-globular › cAMP-dependent Protein Kinase, Chain A › | 0.67 | 49.0 | 5.03e-01 | 86.3% | 83.3% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 49.0 | 4.48e-01 | 92.2% | 61.5% |
| 1hwyA01 | 1.10.287.140 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 43.0 | 4.38e-01 | 100.0% | 68.6% |
| 2vk9A03 | 1.10.3730.30 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.64 | 57.0 | 4.59e-01 | 100.0% | 76.5% |
| 2aj6A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.64 | 48.0 | 3.75e-01 | 94.1% | 35.8% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 51.0 | 4.36e-01 | 84.3% | 63.6% |
| 2f22A00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.64 | 55.0 | 3.93e-01 | 100.0% | 33.8% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.64 | 49.0 | 4.30e-01 | 92.2% | 56.8% |
| 3umgA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.63 | 52.0 | 4.78e-01 | 98.0% | 69.0% |
| 2j3tD01 | 3.30.450.70 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.63 | 48.0 | 3.56e-01 | 90.2% | 31.3% |
| 4evxA00 | 1.10.1740.240 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.63 | 52.0 | 4.23e-01 | 100.0% | 48.5% |
| 3iylB02 | 1.10.2050.10 | Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 | 0.61 | 53.0 | 3.93e-01 | 100.0% | 54.5% |
| 3d2fA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.61 | 53.0 | 4.53e-01 | 100.0% | 89.3% |
| 3natA01 | 3.40.50.11250 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF3013 | 0.60 | 52.0 | 3.67e-01 | 100.0% | 32.7% |
| 8be0A01 | 3.40.91.90 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain | 0.60 | 47.0 | 3.19e-01 | 88.2% | 23.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.59 | 46.0 | 3.84e-01 | 84.3% | 51.8% |
| 3fayA00 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.58 | 52.0 | 3.10e-01 | 100.0% | 99.5% |
| 6lqfA01 | 1.10.150.60 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › ARID DNA-binding domain | 0.58 | 44.0 | 3.60e-01 | 84.3% | 47.0% |
| 3mfiA03 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.58 | 41.0 | 3.61e-01 | 82.4% | 51.3% |
| 2bskB00 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.57 | 50.0 | 4.66e-01 | 100.0% | 87.7% |
| 2looA02 | 1.10.10.1740 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Transmembrane protein 14-like | 0.57 | 43.0 | 3.84e-01 | 90.2% | 56.0% |
| 4uhwA09 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.57 | 41.0 | 3.39e-01 | 96.1% | 40.6% |
| 4ywoA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.56 | 49.0 | 3.25e-01 | 100.0% | 83.5% |
| 8e7cA02 | 1.10.1840.10 | Mainly Alpha › Orthogonal Bundle › main proteinase (3clpro) structure, domain 3 › main proteinase (3clpro) structure, domain 3 | 0.55 | 43.0 | 3.53e-01 | 86.3% | 98.0% |
| 3d0cB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 42.0 | 2.68e-01 | 90.2% | 83.3% |
| 2qbyA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 47.0 | 3.29e-01 | 100.0% | 82.1% |
| 1gvfB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 42.0 | 2.70e-01 | 94.1% | 24.0% |
| 3ftdA02 | 1.10.8.100 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain | 0.52 | 43.0 | 4.01e-01 | 92.2% | 88.9% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.51 | 43.0 | 3.72e-01 | 100.0% | 69.0% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4602761 | 105.2.1.91 ↗ | alpha duplicates or obligate multimers › HLH-like › Dimerization domain in LRIM1/APL1C › Dimerization domain in LRIM1/APL1C › SPICE | 0.82 | 60.0 | 4.31e-01 | 76.5% | 40.0% |
| 3596488 | 3737.1.1.0 ↗ | alpha duplicates or obligate multimers › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats | 0.80 | 58.0 | 4.25e-01 | 82.4% | 31.2% |
| 4019076 | 148.1.3.212 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_13 | 0.75 | 62.0 | 4.82e-01 | 100.0% | 42.7% |
| 3475067 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.74 | 65.0 | 4.00e-01 | 100.0% | 16.7% |
| 4431704 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.73 | 55.0 | 4.93e-01 | 80.4% | 75.7% |
| 3685065 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.72 | 62.0 | 3.77e-01 | 100.0% | 15.6% |
| 4078503 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.71 | 56.0 | 5.08e-01 | 100.0% | 64.6% |
| 4984581 | 283.1.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase | 0.69 | 57.0 | 3.90e-01 | 92.2% | 27.3% |
| 5032595 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.69 | 55.0 | 3.12e-01 | 86.3% | 10.0% |
| 3191600 | 321.1.1.0 ↗ | a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase | 0.67 | 58.0 | 3.78e-01 | 100.0% | 22.9% |
| 3608391 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.67 | 61.0 | 4.33e-01 | 100.0% | 73.8% |
| 5047136 | 2003.1.5.12 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase | 0.67 | 60.0 | 3.47e-01 | 100.0% | 23.8% |
| 3582305 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.66 | 60.0 | 3.88e-01 | 100.0% | 35.5% |
| 3588334 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 56.0 | 4.18e-01 | 98.0% | 38.4% |
| 3214493 | 2004.1.1.530 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, AAA_lid_3 | 0.66 | 55.0 | 3.41e-01 | 100.0% | 26.0% |
| 3491114 | 101.1.10.6 ↗ | alpha arrays › HTH › HTH › Cyclin-like › RB_A | 0.65 | 55.0 | 3.46e-01 | 100.0% | 19.6% |
| 3934455 | 216.1.1.17 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Med15_C | 0.65 | 49.0 | 3.78e-01 | 88.2% | 36.5% |
| 5001603 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.65 | 49.0 | 4.05e-01 | 82.4% | 91.1% |
| 5068089 | 283.1.1.0 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase | 0.64 | 57.0 | 4.38e-01 | 100.0% | 45.2% |
| 4242982 | 4120.1.1.1 ↗ | few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › zf-Tim10_DDP | 0.64 | 55.0 | 4.90e-01 | 94.1% | 85.7% |
| 3279611 | 5049.1.3.0 ↗ | alpha complex topology › Ammonium transporter-related › Ammonium transporter-related › Na(+)-translocating NADH-quinone reductase subunit B | 0.64 | 56.0 | 3.46e-01 | 100.0% | 18.6% |
| 3189017 | 5001.1.1.131 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF7702 | 0.63 | 49.0 | 3.19e-01 | 88.2% | 90.6% |
| 3800977 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.62 | 54.0 | 3.39e-01 | 100.0% | 18.3% |
| 3838282 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.62 | 54.0 | 4.43e-01 | 100.0% | 53.7% |
| 3591291 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.62 | 51.0 | 3.43e-01 | 100.0% | 23.6% |
| 5040221 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.60 | 53.0 | 3.30e-01 | 100.0% | 86.7% |
| 4175809 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.59 | 54.0 | 3.71e-01 | 100.0% | 84.2% |
| 3742760 | 4120.1.1.1 ↗ | few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › zf-Tim10_DDP | 0.59 | 50.0 | 4.22e-01 | 94.1% | 61.9% |
| 3195747 | 3788.1.1.0 ↗ | alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) | 0.57 | 51.0 | 4.62e-01 | 100.0% | 72.9% |
| 4505114 | 6130.1.1.0 ↗ | alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain | 0.56 | 45.0 | 4.27e-01 | 96.1% | 75.4% |
| 4053116 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.54 | 43.0 | 3.86e-01 | 96.1% | 73.8% |
| 3601375 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 43.0 | 2.88e-01 | 100.0% | 21.3% |
| 3812063 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.52 | 49.0 | 3.11e-01 | 100.0% | 44.8% |