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MK422448.1__QBQ71874.1__X__00057

Bact-Vir

MK422448.1__QBQ71874.1__X__00057

Identity

Accession:
MK422448 ↗
Kingdom:
phage

Quality

83.5 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Klebsiella_phage_ST512-KPC3phi13.3

TaxID: 2510471

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 162-215
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jleA00 6.10.280.180 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium RESA, N-terminal helical domain 0.90 78.0 5.53e-01 94.4% 35.6%
3bk2A03 3.10.20.580 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.88 73.0 5.83e-01 90.7% 48.5%
3iylU02 1.10.287.1520 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.85 64.0 6.50e-01 81.5% 83.0%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.82 69.0 5.42e-01 100.0% 46.7%
3of4A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.81 61.0 4.03e-01 85.2% 21.3%
3da1A03 1.10.8.870 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Alpha-glycerophosphate oxidase, cap domain 0.79 59.0 4.32e-01 79.6% 31.6%
5l3wA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.79 59.0 5.10e-01 90.7% 52.4%
3ed5A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.78 60.0 5.14e-01 83.3% 53.6%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.78 62.0 5.82e-01 98.1% 70.1%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.78 61.0 6.22e-01 88.9% 96.2%
4i8oA04 6.10.250.2650 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 55.0 4.47e-01 79.6% 42.9%
1kf6D00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.75 63.0 4.95e-01 96.3% 51.3%
5svlA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.75 64.0 5.97e-01 96.3% 83.8%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 52.0 4.09e-01 74.1% 40.6%
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.74 57.0 4.89e-01 87.0% 53.3%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 57.0 4.93e-01 83.3% 77.8%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.73 56.0 4.64e-01 85.2% 46.0%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 53.0 3.79e-01 77.8% 59.4%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 50.0 4.81e-01 72.2% 67.7%
2lo0A00 1.10.286.70 Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › Get5 dimerization domain 0.70 51.0 5.50e-01 79.6% 93.3%
4ex8A00 3.40.1790.10 Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain 0.70 56.0 3.47e-01 88.9% 16.3%
1dj2A02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.70 55.0 4.57e-01 98.1% 48.5%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 48.0 4.44e-01 72.2% 60.9%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.69 48.0 4.62e-01 72.2% 85.2%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.69 47.0 4.27e-01 70.4% 54.3%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 57.0 5.36e-01 96.3% 80.9%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 54.0 4.91e-01 87.0% 67.6%
6zxqA01 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.68 54.0 4.65e-01 100.0% 53.8%
3aogA01 1.10.8.1210 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.67 40.0 3.86e-01 83.3% 53.2%
1pixA03 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.67 56.0 3.55e-01 98.1% 43.5%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.67 53.0 4.80e-01 85.2% 64.8%
3kd3A02 1.10.150.210 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 0.67 44.0 4.31e-01 70.4% 61.7%
3fedA03 1.20.930.40 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain 0.67 59.0 4.24e-01 100.0% 95.5%
1i2kA01 3.30.470.10 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain 0.66 49.0 4.01e-01 98.1% 41.7%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.65 54.0 4.48e-01 92.6% 74.2%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 57.0 4.09e-01 100.0% 69.6%
2cobA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.64 37.0 3.96e-01 83.3% 65.9%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.64 50.0 4.76e-01 85.2% 76.6%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 46.0 4.11e-01 77.8% 73.1%
1vhxB00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.63 51.0 3.81e-01 90.7% 55.1%
3zdmB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.62 41.0 4.29e-01 72.2% 74.0%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.60 49.0 4.61e-01 88.9% 81.5%
3a7rA02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.59 46.0 3.93e-01 85.2% 100.0%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.59 51.0 4.55e-01 100.0% 67.5%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.59 46.0 4.43e-01 88.9% 100.0%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.59 49.0 4.76e-01 96.3% 87.1%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 4.71e-01 100.0% 91.2%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 46.0 4.36e-01 96.3% 98.5%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.54 43.0 3.88e-01 94.4% 100.0%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.54 47.0 4.65e-01 98.1% 93.1%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3740910 1008.1.1.0 ↗ alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.91 80.0 7.96e-01 94.4% 96.4%
1288509 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.91 79.0 5.50e-01 94.4% 33.3%
3515411 3877.1.1.0 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.88 77.0 5.08e-01 96.3% 25.9%
3400382 3877.1.1.1 ↗ alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP 0.86 76.0 4.70e-01 96.3% 18.9%
3392260 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.86 75.0 6.84e-01 96.3% 74.3%
3786677 3826.1.1.0 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.86 74.0 7.38e-01 94.4% 100.0%
3265542 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.82 61.0 6.62e-01 85.2% 100.0%
4016157 6026.1.1.1 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.82 68.0 5.06e-01 92.6% 37.8%
4976409 283.1.1.0 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase 0.82 70.0 5.48e-01 94.4% 48.2%
3721541 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.79 67.0 5.52e-01 98.1% 54.0%
3643105 6026.1.1.1 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.78 65.0 4.70e-01 94.4% 34.8%
3525680 633.24.1.2 ↗ alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 0.78 70.0 6.22e-01 100.0% 82.7%
4981035 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.76 65.0 6.15e-01 98.1% 92.3%
3686609 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.76 61.0 5.23e-01 90.7% 55.6%
3989934 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.75 62.0 5.94e-01 96.3% 98.5%
3699443 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 60.0 4.66e-01 87.0% 43.5%
3723174 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.74 52.0 4.65e-01 74.1% 56.0%
3539738 10.12.1.1 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding 0.74 55.0 3.58e-01 79.6% 20.4%
5047182 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 60.0 5.73e-01 96.3% 86.2%
3940797 198.1.1.0 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.71 60.0 5.31e-01 100.0% 64.3%
None — 0.71 59.0 3.42e-01 94.4% 10.7%
3810044 198.1.1.2 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 0.71 60.0 5.42e-01 100.0% 70.7%
3700089 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 53.0 4.95e-01 79.6% 73.8%
3412555 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.70 60.0 4.78e-01 100.0% 46.4%
3258522 601.48.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain 0.69 50.0 4.68e-01 75.9% 67.7%
4109908 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.68 59.0 5.06e-01 96.3% 64.7%
4304916 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.68 56.0 4.77e-01 100.0% 65.0%
4537890 192.17.1.19 ↗ alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › GrpE 0.65 52.0 5.05e-01 100.0% 78.3%
5018020 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 52.0 5.36e-01 87.0% 96.0%
3485413 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.63 51.0 5.26e-01 100.0% 96.0%
3283655 3812.1.1.0 ↗ alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE 0.63 49.0 5.11e-01 100.0% 92.0%
4932313 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 55.0 5.16e-01 100.0% 98.5%
4025064 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.61 52.0 4.96e-01 98.1% 95.4%
5039030 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 50.0 5.04e-01 100.0% 94.5%
3930829 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.57 50.0 4.48e-01 100.0% 70.7%
D2 high residues 227-384
PDB
Domain cluster: rep: MK804891.1__QDB73903.1__2D05_072__00072__D11-147
D3 high residues 778-855
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bg7A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.60 43.0 4.06e-01 93.6% 61.2%
1ugiD00 3.10.450.20 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor 0.59 37.0 3.72e-01 84.6% 61.0%
1uzxA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.57 43.0 3.59e-01 80.8% 55.0%
6s5xA01 2.60.40.3600 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 40.0 4.06e-01 94.9% 77.3%
3v98A03 3.10.450.60 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 39.0 3.48e-01 75.6% 86.2%
3wa2X01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 42.0 4.09e-01 88.5% 75.9%
1b7yA00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 46.0 3.26e-01 97.4% 32.1%
1hc7A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 47.0 3.32e-01 100.0% 86.2%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 41.0 4.29e-01 98.7% 100.0%
3fdwA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 46.0 3.97e-01 100.0% 85.4%
2z0uA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 46.0 3.95e-01 100.0% 87.5%
4a8jB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 40.0 3.04e-01 85.9% 87.3%
1i1iP02 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.52 44.0 3.71e-01 100.0% 68.9%
1ym5A02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.52 39.0 3.23e-01 83.3% 84.8%
2y3vD00 2.170.210.20 Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › Spindle assembly abnormal protein 6, N-terminal domain 0.52 44.0 3.59e-01 96.2% 90.9%
1kutA02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.52 40.0 3.50e-01 89.7% 67.7%
3d2lA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.52 31.0 3.45e-01 82.1% 76.2%
3jvgA01 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.51 43.0 3.46e-01 98.7% 95.4%
1c8zA00 3.20.90.10 Alpha Beta › Alpha-Beta Barrel › Tubby Protein; Chain A › Tubby Protein; Chain A 0.51 36.0 2.63e-01 79.5% 94.0%
6fhvA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 44.0 4.08e-01 97.4% 95.9%
3w15A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.50 43.0 2.87e-01 97.4% 47.3%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3816330 6.1.1.2 ↗ beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil › Kunitz_legume 0.61 54.0 4.15e-01 100.0% 88.9%
3722977 2003.1.5.153 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_25 0.60 50.0 3.60e-01 92.3% 75.1%
None — 0.59 49.0 3.52e-01 92.3% 74.8%
3587060 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.58 43.0 4.40e-01 97.4% 84.0%
3198151 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.58 45.0 4.23e-01 97.4% 67.0%
3366631 60.1.2.4 ↗ beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › PF29334 0.57 43.0 3.10e-01 79.5% 81.4%
3758281 223.2.1.4 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › DENN,uDENN 0.57 39.0 3.04e-01 92.3% 31.7%
5081827 206.1.1.9 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.56 43.0 3.04e-01 85.9% 48.7%
3785788 5.1.4.31 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Lgl_C 0.56 47.0 2.86e-01 93.6% 31.0%
None — 0.55 46.0 3.19e-01 94.9% 27.7%
3869745 2007.1.2.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.55 48.0 3.60e-01 97.4% 87.7%
3460220 314.1.1.2 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_2b 0.55 41.0 3.29e-01 85.9% 40.0%
3320258 5.1.5.66 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › FBA_1 0.55 42.0 2.86e-01 84.6% 36.3%
3669849 60.1.2.4 ↗ beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › PF29334 0.55 41.0 2.84e-01 80.8% 74.2%
3705941 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.54 38.0 3.85e-01 89.7% 73.8%
3424861 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.53 44.0 2.90e-01 94.9% 97.4%
4483150 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.53 37.0 2.95e-01 71.8% 50.0%
3368394 4325.1.1.11 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like › PF27041 0.53 37.0 3.50e-01 76.9% 60.0%
3907624 60.1.1.14 ↗ beta barrels › SPOC domain-like › SPOC domain-related › SPOC domain › PF29334 0.53 39.0 3.13e-01 79.5% 77.0%
156548 844.1.1.1 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Tub 0.53 39.0 2.74e-01 79.5% 31.5%
3328359 844.1.1.2 ↗ beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › LOR 0.53 39.0 2.98e-01 80.8% 97.9%
3818341 331.9.1.4 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › Coatomer_g_Cpla 0.53 34.0 3.49e-01 87.2% 66.7%
3395020 11.1.4.3 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › CBM_20 0.52 44.0 3.94e-01 98.7% 80.8%
4928365 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 40.0 4.00e-01 85.9% 100.0%
3385295 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.52 40.0 2.94e-01 85.9% 43.4%
2557441 3414.1.1.2 ↗ beta sandwiches › A putative surface protein › A putative surface protein › A putative surface protein › Rib 0.52 37.0 3.74e-01 96.2% 74.7%
3481723 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.51 41.0 3.67e-01 88.5% 98.3%
None — 0.51 37.0 3.74e-01 93.6% 77.5%
3923273 206.1.1.44 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF1679 0.51 43.0 2.79e-01 98.7% 34.4%
4931272 220.1.1.76 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 0.51 39.0 3.69e-01 83.3% 72.6%
4877957 3414.1.1.2 ↗ beta sandwiches › A putative surface protein › A putative surface protein › A putative surface protein › Rib 0.51 36.0 3.04e-01 94.9% 39.6%
5022744 304.112.1.0 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.51 39.0 3.30e-01 98.7% 48.1%
4633591 222.1.1.17 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N 0.51 39.0 3.22e-01 87.2% 85.6%
3384667 2484.1.1.157 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF4371 0.50 37.0 2.38e-01 79.5% 14.6%
3701764 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.50 43.0 3.60e-01 100.0% 75.9%
5039031 220.1.1.76 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 0.50 40.0 3.61e-01 88.5% 87.3%
3752886 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.50 33.0 3.12e-01 82.1% 51.4%
3629488 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.50 36.0 3.21e-01 76.9% 66.1%
D4 medium residues 79-161
PDB
Domain cluster: representative
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.86 67.0 6.24e-01 81.9% 81.4%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.82 52.0 4.70e-01 95.2% 49.1%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.82 62.0 6.01e-01 79.5% 77.2%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.81 63.0 5.77e-01 83.1% 84.1%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.80 66.0 5.84e-01 88.0% 85.5%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.80 70.0 5.93e-01 95.2% 88.0%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.78 67.0 5.05e-01 94.0% 89.8%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 64.0 6.44e-01 90.4% 89.0%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.77 56.0 5.24e-01 75.9% 67.6%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 45.0 3.62e-01 74.7% 31.2%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 68.0 4.80e-01 95.2% 34.7%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 64.0 5.81e-01 100.0% 67.9%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.76 58.0 4.94e-01 86.7% 50.4%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.76 63.0 5.77e-01 90.4% 86.2%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 57.0 5.84e-01 84.3% 87.2%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 63.0 4.56e-01 96.4% 35.1%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 58.0 5.28e-01 86.7% 77.1%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 63.0 4.67e-01 96.4% 39.2%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.72 49.0 3.77e-01 71.1% 36.8%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.71 54.0 4.46e-01 81.9% 94.0%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.71 54.0 4.73e-01 81.9% 89.6%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.71 63.0 5.20e-01 96.4% 57.4%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.70 59.0 4.97e-01 96.4% 55.7%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 60.0 5.46e-01 95.2% 92.8%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.69 54.0 4.87e-01 83.1% 61.4%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 51.0 4.68e-01 89.2% 60.9%
6klvB00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.67 56.0 3.56e-01 90.4% 31.4%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.66 55.0 4.64e-01 89.2% 68.9%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.66 53.0 4.04e-01 89.2% 36.5%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.66 46.0 4.46e-01 84.3% 64.8%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.66 48.0 4.66e-01 75.9% 75.6%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.65 47.0 4.09e-01 75.9% 72.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 47.0 4.23e-01 78.3% 60.8%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.65 42.0 4.24e-01 78.3% 64.7%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 50.0 5.20e-01 84.3% 92.0%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.64 53.0 4.76e-01 91.6% 79.0%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.63 54.0 5.13e-01 91.6% 90.6%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 47.0 3.83e-01 78.3% 99.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 45.0 4.07e-01 84.3% 55.1%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 40.0 4.58e-01 74.7% 96.6%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 43.0 4.54e-01 77.1% 86.5%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 4.32e-01 91.6% 61.7%
3qf7A02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 39.0 4.44e-01 74.7% 100.0%
2q5zB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.54 38.0 3.70e-01 77.1% 66.0%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3928340 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.85 79.0 5.94e-01 100.0% 94.6%
3927737 632.8.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.85 56.0 5.34e-01 75.9% 58.9%
4220640 5001.1.1.64 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PalH 0.81 62.0 4.37e-01 79.5% 29.4%
3359095 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.81 57.0 6.02e-01 77.1% 81.3%
3962942 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.81 72.0 5.84e-01 96.4% 53.3%
4075707 3711.1.1.0 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.81 69.0 6.62e-01 94.0% 82.1%
3784055 192.24.1.0 ↗ alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.80 70.0 5.96e-01 95.2% 80.8%
3282043 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.79 67.0 6.71e-01 95.2% 88.2%
3909706 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 61.0 6.11e-01 81.9% 80.0%
4593595 3835.1.1.0 ↗ alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein 0.79 67.0 4.91e-01 94.0% 61.9%
3418815 3755.3.1.366 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7653 0.78 60.0 5.14e-01 94.0% 53.6%
5047547 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.78 62.0 5.56e-01 86.7% 74.8%
3823336 4207.1.1.0 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.77 68.0 6.03e-01 100.0% 67.8%
3691337 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.76 66.0 4.88e-01 96.4% 48.8%
3281127 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.76 67.0 6.57e-01 96.4% 91.1%
3545387 3602.1.1.0 ↗ alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.75 68.0 6.12e-01 100.0% 72.7%
3740499 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.75 66.0 4.78e-01 96.4% 52.9%
3524013 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 66.0 4.04e-01 98.8% 16.2%
3175197 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.75 67.0 5.73e-01 97.6% 65.4%
4932755 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 66.0 4.87e-01 96.4% 40.5%
3880637 3755.3.1.465 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.74 64.0 5.31e-01 100.0% 55.0%
3463858 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.74 49.0 4.59e-01 71.1% 56.0%
3611289 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.73 66.0 5.40e-01 97.6% 59.3%
3972236 3755.3.1.42 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CheZ 0.72 64.0 4.91e-01 96.4% 46.1%
3896686 192.8.1.36 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain 0.72 59.0 5.51e-01 86.7% 97.0%
3600869 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.72 61.0 5.53e-01 95.2% 80.9%
4649114 3559.1.1.1 ↗ a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.71 58.0 5.50e-01 88.0% 73.0%
3518412 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.71 62.0 4.57e-01 97.6% 38.7%
3592587 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.71 65.0 5.58e-01 98.8% 67.2%
4088407 150.3.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.71 54.0 4.03e-01 80.7% 88.0%
3608012 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.70 55.0 5.48e-01 86.7% 80.0%
3416168 4177.1.1.4 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.70 63.0 4.54e-01 96.4% 86.4%
4523817 310.2.1.1 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.70 57.0 4.33e-01 89.2% 91.3%
3729252 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 61.0 5.45e-01 96.4% 73.0%
3713201 4323.1.1.1 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.69 60.0 4.94e-01 98.8% 53.8%
3906467 1008.1.1.106 ↗ alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › CSN5_C 0.69 56.0 5.44e-01 97.6% 78.9%
5048976 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 60.0 4.98e-01 96.4% 55.2%
3601090 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 58.0 4.43e-01 94.0% 39.5%
3554395 2004.1.1.118 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.69 59.0 3.99e-01 94.0% 29.0%
3264876 604.12.1.42 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF202 0.68 50.0 4.73e-01 78.3% 75.0%
3876247 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 57.0 4.95e-01 89.2% 87.5%
3313420 611.9.1.4 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.67 58.0 4.87e-01 96.4% 57.1%
4042007 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.64 53.0 4.79e-01 95.2% 67.3%
4947163 601.30.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › MMR_HSR1 0.59 48.0 3.97e-01 91.6% 65.0%
3720769 2004.1.1.118 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.58 48.0 3.27e-01 94.0% 64.5%
3407923 192.24.1.1 ↗ alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical 0.56 49.0 4.61e-01 94.0% 84.0%
3746549 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 40.0 3.53e-01 85.5% 55.2%
D5 medium residues 418-530
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5hyhA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.62 46.0 3.41e-01 77.0% 98.3%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.59 47.0 3.36e-01 84.1% 78.9%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 46.0 4.12e-01 85.0% 71.5%
8hixR01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 44.0 3.30e-01 78.8% 53.7%
2l6xA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 49.0 3.99e-01 97.3% 67.2%
1ikpA02 3.90.1350.10 Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain 0.57 44.0 3.95e-01 90.3% 58.2%
2pbxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 41.0 3.41e-01 74.3% 50.8%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.56 45.0 4.52e-01 85.0% 84.1%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.56 43.0 4.15e-01 81.4% 91.3%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 44.0 4.33e-01 85.0% 90.0%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.54 43.0 3.55e-01 85.8% 71.2%
8h8jC01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 40.0 3.08e-01 77.9% 86.7%
7sf7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 41.0 3.08e-01 79.6% 48.7%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 42.0 4.03e-01 85.0% 85.8%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 43.0 3.06e-01 89.4% 73.0%
5x56B00 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.53 41.0 4.25e-01 81.4% 89.5%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 45.0 4.64e-01 90.3% 97.2%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 41.0 4.13e-01 84.1% 89.7%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.52 35.0 3.17e-01 78.8% 47.6%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 31.0 3.83e-01 79.6% 100.0%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.52 39.0 3.89e-01 79.6% 91.2%
7qocA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.51 45.0 3.89e-01 100.0% 98.9%
1h97A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.56e-01 77.9% 88.4%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 38.0 3.90e-01 78.8% 90.8%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 4.14e-01 85.8% 97.3%
2qtqB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 36.0 3.06e-01 72.6% 72.6%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 38.0 3.55e-01 82.3% 71.4%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.51 38.0 3.93e-01 79.6% 86.1%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 33.0 3.37e-01 87.6% 68.2%
3f7cA00 1.20.1590.10 Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like 0.50 43.0 3.56e-01 92.9% 68.3%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3858558 4207.1.2.5 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › TEX13 0.68 39.0 4.67e-01 85.8% 85.3%
3270478 6155.1.1.4 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC 0.65 47.0 4.86e-01 75.2% 98.1%
3239812 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.64 49.0 3.90e-01 80.5% 85.8%
3216129 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.64 49.0 4.79e-01 81.4% 85.6%
3254024 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.62 49.0 4.35e-01 86.7% 75.3%
3526949 207.1.1.121 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › TEX13 0.59 44.0 4.39e-01 86.7% 73.3%
3695102 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 3.59e-01 100.0% 48.5%
4015003 109.10.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin 0.58 51.0 4.05e-01 98.2% 84.9%
2072068 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 52.0 4.11e-01 98.2% 73.3%
4010621 1075.5.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 50.0 4.00e-01 95.6% 72.6%
3513005 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 47.0 4.40e-01 87.6% 87.9%
3183105 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.57 49.0 3.97e-01 98.2% 88.5%
143030 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.57 49.0 4.06e-01 99.1% 86.9%
3995514 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 46.0 4.26e-01 87.6% 84.8%
5053992 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 39.0 3.68e-01 70.8% 75.6%
3559622 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 46.0 4.17e-01 87.6% 90.3%
3738901 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.56 48.0 3.97e-01 98.2% 88.8%
60156 109.10.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin 0.55 47.0 3.97e-01 98.2% 86.7%
3780807 174.1.1.52 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 0.55 45.0 4.30e-01 86.7% 85.4%
3251736 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.55 47.0 4.00e-01 100.0% 89.0%
3251353 133.1.1.1 ↗ alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.55 43.0 3.51e-01 85.8% 65.1%
4027330 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.53 48.0 4.64e-01 100.0% 93.1%
3730442 5050.1.1.50 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › DUF1275 0.53 45.0 3.47e-01 91.2% 83.2%
3495233 133.1.1.1 ↗ alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.53 42.0 3.74e-01 83.2% 87.7%
3825046 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 43.0 3.94e-01 86.7% 86.9%
4020167 633.26.1.0 ↗ alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain 0.52 39.0 3.83e-01 78.8% 90.8%
3369476 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.52 46.0 3.72e-01 100.0% 61.8%
5065021 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.52 39.0 3.82e-01 79.6% 91.9%
5027625 3457.1.1.1 ↗ alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Peptidase_A24 0.51 45.0 3.89e-01 97.3% 82.9%
4190833 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.51 36.0 3.59e-01 73.5% 80.0%
D6 medium residues 542-662
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7ep1B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 50.0 3.99e-01 81.0% 72.3%
2lo6A00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 52.0 4.78e-01 86.8% 92.9%
1xd4A04 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.63 48.0 3.99e-01 80.2% 67.9%
3cf6E05 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.62 47.0 3.80e-01 81.0% 63.5%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 51.0 4.71e-01 88.4% 98.0%
1sz9C00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 53.0 5.10e-01 94.2% 97.9%
3wozB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 48.0 3.94e-01 86.0% 62.0%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 49.0 4.71e-01 87.6% 85.0%
1juqC00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 49.0 4.57e-01 86.8% 91.3%
1dvpA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 48.0 4.63e-01 86.8% 97.9%
1hx8A01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 48.0 4.91e-01 86.8% 100.0%
2diwA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 50.0 4.79e-01 91.7% 98.6%
4jxtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 50.0 4.87e-01 90.9% 99.2%
7dvqK01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 48.0 4.29e-01 89.3% 74.6%
6tblB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.57 44.0 4.62e-01 82.6% 93.7%
1x5bA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 47.0 4.59e-01 89.3% 100.0%
5cwkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 46.0 4.21e-01 90.1% 80.4%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.56 31.0 4.12e-01 78.5% 97.1%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.56 36.0 4.17e-01 91.7% 94.0%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.55 49.0 4.83e-01 98.3% 99.2%
1iygA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 39.0 3.85e-01 75.2% 69.9%
1gw5A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.54 47.0 3.07e-01 98.3% 26.5%
3mpiA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.52 39.0 3.93e-01 79.3% 80.2%
4dvgB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 46.0 3.49e-01 100.0% 65.2%
2i9cA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.52 37.0 3.87e-01 99.2% 82.9%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3679473 109.4.1.15 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.71 52.0 4.97e-01 76.0% 96.4%
3494051 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 50.0 4.18e-01 75.2% 54.8%
3593022 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 49.0 3.48e-01 76.0% 36.6%
4030371 109.4.1.21 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ENTH 0.64 52.0 3.77e-01 86.0% 35.9%
3868120 109.4.1.21 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ENTH 0.64 56.0 5.27e-01 95.9% 87.6%
3616424 109.4.1.263 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N 0.63 56.0 4.96e-01 95.9% 92.4%
3479516 109.4.1.263 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N 0.63 52.0 4.29e-01 89.3% 92.7%
4003960 109.4.1.263 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N 0.63 54.0 5.02e-01 94.2% 98.1%
3670612 109.4.1.1255 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 0.63 48.0 3.26e-01 80.2% 31.1%
3275426 109.4.1.21 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ENTH 0.62 50.0 4.77e-01 84.3% 82.1%
3320200 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.62 55.0 5.31e-01 95.9% 94.1%
5058589 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 48.0 4.47e-01 83.5% 66.0%
3550587 109.4.1.15 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.62 51.0 4.63e-01 89.3% 85.5%
3875282 109.4.1.953 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_MROH2B_1st 0.62 51.0 4.33e-01 89.3% 57.0%
3992676 109.4.1.92 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 51.0 3.30e-01 88.4% 20.2%
4543 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.62 54.0 5.08e-01 95.0% 95.8%
3527216 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.62 54.0 5.08e-01 95.9% 92.4%
3252673 109.4.1.94 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANTH 0.61 51.0 4.87e-01 91.7% 84.1%
3349391 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.61 53.0 4.47e-01 95.0% 63.5%
3642665 109.4.1.15 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.60 49.0 4.16e-01 86.8% 66.7%
3447374 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.59 48.0 3.38e-01 86.0% 51.6%
3683126 109.3.1.319 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Adaptin_N 0.59 45.0 4.40e-01 81.8% 73.7%
3520392 109.4.1.1399 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tuberin, DUF3384 0.59 50.0 3.02e-01 94.2% 20.1%
4336397 109.4.1.15 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.59 49.0 4.37e-01 90.1% 77.1%
3438540 109.4.1.1255 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 0.59 48.0 4.16e-01 87.6% 63.8%
3992054 109.4.1.470 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 0.58 49.0 3.78e-01 92.6% 48.6%
3579060 109.4.1.313 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UTP20_N 0.58 48.0 4.03e-01 93.4% 52.0%
3439241 109.4.1.15 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS 0.58 50.0 4.30e-01 94.2% 75.8%
3223123 109.4.1.70 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.57 49.0 4.73e-01 93.4% 100.0%
5036044 109.4.1.124 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_alkylation 0.56 45.0 4.55e-01 86.8% 89.6%
3184986 604.1.1.46 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GCFC 0.56 49.0 4.37e-01 98.3% 90.9%
3739052 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 45.0 3.77e-01 86.0% 66.3%
3343408 109.4.1.1411 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30303 0.55 40.0 4.08e-01 76.9% 80.8%
4644903 109.4.1.3269 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10, TPR_16, TPR_19 0.53 41.0 3.38e-01 95.9% 43.5%
4013731 601.1.1.12 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › AflR 0.52 43.0 4.03e-01 90.1% 94.7%
5043082 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 43.0 3.71e-01 95.0% 57.4%
D7 medium residues 663-771
PDB
Domain cluster: rep: AP014888.1__BAV81104.1__X__00002__D487-573
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3lcvB01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.82 43.0 5.87e-01 84.4% 100.0%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.70 43.0 5.26e-01 93.6% 100.0%
3hx3A01 1.10.8.20 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p 0.67 41.0 5.01e-01 88.1% 100.0%
4gniA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.66 41.0 4.57e-01 83.5% 79.1%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 48.0 5.28e-01 93.6% 98.8%
3t38A01 1.10.8.1060 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Corynebacterium glutamicum thioredoxin-dependent arsenate reductase, N-terminal domain 0.65 42.0 5.01e-01 83.5% 100.0%
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.65 46.0 5.21e-01 90.8% 100.0%
1xn8A00 1.10.3230.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › YqbG-like 0.62 48.0 4.54e-01 81.7% 77.9%
1xf1A01 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.58 46.0 3.32e-01 85.3% 92.7%
3da1A03 1.10.8.870 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Alpha-glycerophosphate oxidase, cap domain 0.58 34.0 3.21e-01 89.0% 45.6%
5x68A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 43.0 3.01e-01 78.0% 91.8%
3dkaB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.57 35.0 3.30e-01 71.6% 49.6%
2ipcA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.54 40.0 3.13e-01 77.1% 77.3%
2vqcA00 1.10.10.1470 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › F-112 protein-like 0.54 24.0 2.91e-01 85.3% 61.4%
6gpxB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 37.0 2.84e-01 71.6% 40.7%
2gutA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.53 34.0 3.93e-01 93.6% 93.5%
4evqA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 43.0 3.49e-01 90.8% 100.0%
1cmbA00 1.10.140.10 Mainly Alpha › Orthogonal Bundle › MET Apo-Repressor, subunit A › MET Apo-Repressor, subunit A 0.51 32.0 3.25e-01 91.7% 64.4%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.50 35.0 2.90e-01 72.5% 83.8%
4cgrB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 39.0 3.37e-01 93.6% 49.2%
5grqA00 1.10.8.810 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Daxx helical bundle domain 0.50 34.0 3.67e-01 70.6% 84.4%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4038683 103.1.1.5 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › FmrO 0.81 45.0 5.89e-01 89.0% 100.0%
3935477 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.68 41.0 4.93e-01 88.1% 94.3%
3411371 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.67 43.0 5.05e-01 89.9% 94.7%
3958294 181.1.1.0 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.65 41.0 4.47e-01 91.7% 77.8%
3580974 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.64 42.0 4.96e-01 89.9% 97.3%
4402126 524.1.1.0 ↗ alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p 0.63 56.0 4.42e-01 98.2% 54.1%
4569712 2003.1.2.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.61 53.0 3.61e-01 94.5% 97.9%
3832681 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.60 37.0 4.00e-01 91.7% 71.6%
3261546 103.1.1.3 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › CRAL_TRIO_N 0.60 41.0 4.57e-01 87.2% 90.6%
4451760 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.58 52.0 4.89e-01 98.2% 89.2%
2644285 3980.1.1.1 ↗ alpha arrays › Protein C' › Protein C' › Protein C' › Paramyxo_C 0.57 41.0 4.10e-01 75.2% 86.6%
3951929 191.1.1.10 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_6 0.56 47.0 4.35e-01 89.9% 74.8%
3813322 109.4.1.927 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN 0.54 38.0 3.05e-01 71.6% 67.4%
4229131 2011.2.1.3 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro 0.53 41.0 3.43e-01 82.6% 91.8%
3389689 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 37.0 3.30e-01 71.6% 56.5%
3707321 603.2.1.0 ↗ alpha bundles › STAT-like › STAT › STAT 0.51 44.0 3.22e-01 94.5% 33.9%
3710567 70.3.1.0 ↗ beta barrels › beta-clip › SET domain-like › SET domain-like 0.51 37.0 2.59e-01 74.3% 48.5%
3834131 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.50 36.0 3.39e-01 74.3% 75.6%