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MK448445.1__QBX09490.1__JavanS344_0018__00018
Bact-VirMK448445.1__QBX09490.1__JavanS344_0018__00018
Identity
- Accession:
- MK448445 ↗
- Kingdom:
- phage
Quality
88.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-136
Domain cluster:
rep: MZ417522.1__QXN67731.1__X__00014__D5-37_64-148
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07374.18 best | DUF1492 | 40.4 | 3.80e-10 | 74.6% | 78.0% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5fgmA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.86 | 39.0 | 5.70e-01 | 95.5% | 92.3% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 58.0 | 4.69e-01 | 96.3% | 40.3% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.82 | 60.0 | 5.25e-01 | 76.1% | 74.9% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.79 | 35.0 | 4.56e-01 | 93.3% | 72.7% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 48.0 | 6.08e-01 | 96.3% | 100.0% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 41.0 | 5.61e-01 | 97.0% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 58.0 | 5.30e-01 | 76.1% | 65.9% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 55.0 | 6.37e-01 | 94.8% | 96.0% |
| 3zbhA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.78 | 49.0 | 5.95e-01 | 97.0% | 94.4% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 52.0 | 5.34e-01 | 76.1% | 72.2% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 51.0 | 5.86e-01 | 84.3% | 91.9% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.76 | 49.0 | 5.91e-01 | 98.5% | 98.9% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.75 | 47.0 | 5.77e-01 | 97.0% | 97.7% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.75 | 57.0 | 4.21e-01 | 79.9% | 85.5% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 55.0 | 6.22e-01 | 97.0% | 100.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 48.0 | 4.96e-01 | 76.1% | 70.6% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.72 | 47.0 | 5.74e-01 | 99.3% | 98.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 51.0 | 5.67e-01 | 76.1% | 94.2% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 45.0 | 4.96e-01 | 73.9% | 78.3% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.72 | 44.0 | 5.26e-01 | 73.9% | 94.2% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.71 | 53.0 | 3.97e-01 | 77.6% | 41.5% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 55.0 | 4.53e-01 | 90.3% | 47.6% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 52.0 | 4.21e-01 | 76.1% | 64.1% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 45.0 | 4.98e-01 | 76.1% | 81.9% |
| 3pwfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 36.0 | 3.70e-01 | 97.0% | 50.4% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.69 | 45.0 | 5.07e-01 | 96.3% | 87.1% |
| 1rp3G02 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.69 | 42.0 | 4.18e-01 | 100.0% | 58.5% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 58.0 | 5.03e-01 | 89.6% | 81.2% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 58.0 | 5.81e-01 | 92.5% | 95.7% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 49.0 | 4.59e-01 | 96.3% | 64.0% |
| 3onqA03 | 1.10.10.2840 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain | 0.64 | 37.0 | 3.79e-01 | 91.0% | 57.3% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 56.0 | 4.51e-01 | 95.5% | 51.9% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 57.0 | 4.72e-01 | 96.3% | 66.0% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.60 | 50.0 | 3.76e-01 | 88.8% | 92.2% |
| 7wivA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 50.0 | 3.80e-01 | 88.1% | 98.0% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.60 | 51.0 | 5.02e-01 | 90.3% | 97.9% |
| 3kdqA00 | 6.10.320.10 | Special › Helix non-globular › Ferritin › | 0.59 | 55.0 | 5.26e-01 | 99.3% | 99.3% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.59 | 55.0 | 4.61e-01 | 99.3% | 85.0% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.58 | 52.0 | 5.07e-01 | 96.3% | 93.2% |
| 3qa8A04 | 1.20.1270.250 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 54.0 | 4.39e-01 | 100.0% | 66.1% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 47.0 | 4.16e-01 | 95.5% | 97.6% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 32.0 | 3.62e-01 | 85.1% | 74.8% |
| 3aonA00 | 1.10.287.3240 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 46.0 | 4.13e-01 | 96.3% | 78.7% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 49.0 | 3.82e-01 | 100.0% | 68.2% |
ECOD (60)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4202221 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.86 | 43.0 | 6.13e-01 | 85.8% | 98.5% |
| 4937862 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.86 | 57.0 | 6.26e-01 | 96.3% | 81.8% |
| 4683276 | 101.1.1.42 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 | 0.85 | 46.0 | 5.49e-01 | 85.1% | 75.8% |
| 4001187 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.85 | 60.0 | 5.40e-01 | 71.6% | 94.3% |
| 3732045 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.84 | 55.0 | 4.34e-01 | 99.3% | 34.9% |
| 3192846 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.84 | 54.0 | 5.58e-01 | 97.0% | 69.6% |
| 4963973 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.83 | 62.0 | 5.68e-01 | 76.9% | 61.8% |
| 3598120 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 57.0 | 6.00e-01 | 98.5% | 77.5% |
| 4219465 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.83 | 56.0 | 6.19e-01 | 91.0% | 83.6% |
| 3284621 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.82 | 52.0 | 6.44e-01 | 96.3% | 100.0% |
| 3470739 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 58.0 | 4.82e-01 | 96.3% | 44.7% |
| 4041347 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.82 | 55.0 | 6.06e-01 | 90.3% | 82.7% |
| 3788782 | 2004.1.1.199 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B | 0.82 | 58.0 | 3.74e-01 | 93.3% | 18.6% |
| 3215342 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 56.0 | 6.61e-01 | 99.3% | 97.9% |
| 3711734 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.82 | 55.0 | 5.04e-01 | 96.3% | 55.2% |
| 3608116 | 5086.1.1.177 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 | 0.82 | 55.0 | 5.33e-01 | 96.3% | 62.8% |
| 3199608 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.79 | 57.0 | 6.26e-01 | 74.6% | 89.1% |
| 4017285 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 56.0 | 4.86e-01 | 96.3% | 50.5% |
| 4016635 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.79 | 54.0 | 6.21e-01 | 97.0% | 93.0% |
| 3933335 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.78 | 59.0 | 3.82e-01 | 93.3% | 19.3% |
| 3271160 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.77 | 55.0 | 4.59e-01 | 93.3% | 45.0% |
| None | — | 0.77 | 68.0 | 5.61e-01 | 93.3% | 56.4% | |
| 3961790 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.76 | 55.0 | 5.61e-01 | 98.5% | 76.2% |
| 3447097 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.76 | 53.0 | 5.87e-01 | 76.1% | 87.3% |
| 3282761 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.76 | 51.0 | 5.92e-01 | 99.3% | 95.8% |
| 5065057 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.76 | 53.0 | 5.06e-01 | 99.3% | 61.9% |
| 1171038 | 3755.3.1.148 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC | 0.76 | 58.0 | 5.05e-01 | 78.4% | 94.8% |
| 3524877 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.76 | 54.0 | 4.46e-01 | 76.1% | 42.1% |
| 3406218 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.76 | 55.0 | 6.09e-01 | 76.1% | 91.8% |
| 3595707 | 5086.1.1.118 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp | 0.74 | 66.0 | 6.69e-01 | 94.0% | 98.5% |
| 3804937 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.73 | 53.0 | 4.96e-01 | 93.3% | 61.9% |
| 5020818 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 58.0 | 3.81e-01 | 96.3% | 22.5% |
| 3915380 | 192.5.1.25 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PTHB1_hp | 0.73 | 48.0 | 5.74e-01 | 89.6% | 98.9% |
| 3470779 | 3755.3.1.420 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PTHB1_hp | 0.73 | 62.0 | 5.22e-01 | 89.6% | 99.1% |
| 5041482 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.73 | 47.0 | 5.44e-01 | 100.0% | 91.6% |
| 4936791 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.73 | 58.0 | 3.89e-01 | 93.3% | 24.5% |
| 4935333 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.72 | 57.0 | 5.48e-01 | 93.3% | 73.3% |
| 4003222 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.71 | 51.0 | 5.77e-01 | 79.9% | 99.0% |
| 4424383 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.71 | 53.0 | 4.78e-01 | 98.5% | 58.3% |
| 3643902 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 52.0 | 5.33e-01 | 77.6% | 77.7% |
| 3919843 | 604.1.1.124 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 | 0.71 | 50.0 | 5.08e-01 | 74.6% | 73.8% |
| 3819281 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.70 | 56.0 | 4.86e-01 | 100.0% | 56.4% |
| 5012037 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.69 | 42.0 | 5.22e-01 | 100.0% | 92.2% |
| 3972713 | 101.1.1.42 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4_2 | 0.69 | 41.0 | 4.76e-01 | 86.6% | 82.1% |
| 3627888 | 101.1.1.64 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › tRNA_bind_2 | 0.67 | 42.0 | 4.42e-01 | 100.0% | 68.8% |
| 4024517 | 101.1.1.64 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › tRNA_bind_2 | 0.67 | 41.0 | 4.48e-01 | 100.0% | 73.0% |
| 4030265 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.67 | 49.0 | 4.33e-01 | 76.1% | 52.6% |
| 2126785 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.65 | 58.0 | 5.39e-01 | 94.0% | 95.1% |
| 5011671 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 41.0 | 4.71e-01 | 100.0% | 85.0% |
| 3583684 | 148.1.3.11 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › MT | 0.65 | 55.0 | 4.28e-01 | 93.3% | 44.4% |
| 3977260 | 101.1.1.39 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Phage_antitermQ | 0.63 | 50.0 | 5.25e-01 | 100.0% | 91.7% |
| 4982831 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.62 | 56.0 | 3.74e-01 | 95.5% | 50.5% |
| 3613962 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.62 | 53.0 | 3.87e-01 | 93.3% | 93.2% |
| 4106959 | 4177.1.1.120 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF29569 | 0.61 | 58.0 | 4.99e-01 | 100.0% | 85.6% |
| 3615971 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.60 | 57.0 | 4.97e-01 | 100.0% | 89.5% |
| 3897765 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.60 | 50.0 | 4.98e-01 | 89.6% | 100.0% |
| 4577850 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.59 | 41.0 | 4.77e-01 | 100.0% | 97.0% |
| 3600398 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.55 | 51.0 | 4.54e-01 | 100.0% | 90.8% |
| 4388780 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.51 | 38.0 | 3.75e-01 | 77.6% | 100.0% |
| 3390613 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.50 | 46.0 | 4.71e-01 | 97.8% | 100.0% |
D2
high
residues 141-238
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3fm5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 47.0 | 4.30e-01 | 73.5% | 74.6% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 33.0 | 3.77e-01 | 87.8% | 66.7% |
| 2nyxB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 45.0 | 4.03e-01 | 76.5% | 77.5% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.60 | 34.0 | 3.35e-01 | 73.5% | 50.5% |
| 3qxfA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.59 | 46.0 | 3.22e-01 | 83.7% | 42.1% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 36.0 | 3.44e-01 | 95.9% | 53.3% |
| 1z72A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.56 | 48.0 | 3.80e-01 | 96.9% | 89.8% |
| 2k9lA00 | 1.10.10.1330 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA polymerase sigma-54 factor, core-binding domain | 0.56 | 38.0 | 4.23e-01 | 86.7% | 89.5% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.56 | 39.0 | 3.56e-01 | 71.4% | 87.9% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 38.0 | 3.07e-01 | 72.4% | 87.8% |
| 2xubA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 35.0 | 3.83e-01 | 79.6% | 80.8% |
| 4hteA01 | 1.20.58.1730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 40.0 | 3.52e-01 | 76.5% | 74.8% |
| 4xzjA01 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.53 | 44.0 | 3.44e-01 | 89.8% | 57.3% |
| 2w9yA00 | 1.20.120.1100 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 47.0 | 4.21e-01 | 98.0% | 92.6% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 45.0 | 3.31e-01 | 100.0% | 68.7% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.51 | 30.0 | 3.13e-01 | 100.0% | 62.2% |
| 1lkvX02 | 1.10.220.30 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain | 0.51 | 45.0 | 4.13e-01 | 100.0% | 90.9% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.50 | 40.0 | 3.50e-01 | 88.8% | 77.5% |
| 4hfkB00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.50 | 35.0 | 3.56e-01 | 72.4% | 96.9% |
| 4hteA03 | 1.10.167.30 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › | 0.50 | 32.0 | 3.51e-01 | 83.7% | 80.0% |
ECOD (48)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4165729 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.85 | 61.0 | 5.01e-01 | 73.5% | 43.6% |
| 3589001 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.83 | 75.0 | 7.27e-01 | 100.0% | 88.0% |
| 3974118 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.81 | 68.0 | 7.14e-01 | 99.0% | 97.8% |
| 3946805 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.78 | 55.0 | 6.15e-01 | 73.5% | 94.7% |
| 4148139 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.77 | 56.0 | 4.79e-01 | 76.5% | 48.4% |
| 4518447 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.77 | 56.0 | 5.42e-01 | 76.5% | 68.2% |
| 3978620 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.76 | 56.0 | 4.66e-01 | 76.5% | 45.5% |
| 4253265 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.76 | 55.0 | 4.61e-01 | 75.5% | 46.1% |
| 4084282 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.76 | 56.0 | 5.96e-01 | 76.5% | 88.2% |
| 3297365 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.75 | 55.0 | 4.53e-01 | 76.5% | 44.4% |
| 4034281 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.75 | 68.0 | 6.53e-01 | 100.0% | 93.6% |
| 4340199 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.74 | 67.0 | 5.89e-01 | 100.0% | 82.8% |
| 3329805 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.73 | 53.0 | 4.50e-01 | 75.5% | 47.5% |
| 3339569 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.73 | 53.0 | 5.53e-01 | 75.5% | 84.3% |
| 4511316 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.72 | 50.0 | 4.41e-01 | 83.7% | 49.6% |
| 3428775 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.72 | 52.0 | 3.65e-01 | 76.5% | 23.8% |
| 3027028 | 101.1.1.31 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r4 | 0.68 | 52.0 | 5.05e-01 | 82.7% | 72.5% |
| 5051432 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 40.0 | 3.12e-01 | 71.4% | 42.1% |
| 3403176 | 7023.1.1.1 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT | 0.58 | 46.0 | 3.90e-01 | 86.7% | 92.9% |
| 3595988 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 44.0 | 3.38e-01 | 81.6% | 89.8% |
| 4429835 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.57 | 49.0 | 4.91e-01 | 96.9% | 100.0% |
| 3950039 | 5086.1.1.229 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › QcrA_N | 0.56 | 34.0 | 3.30e-01 | 96.9% | 52.7% |
| 4044992 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 49.0 | 4.87e-01 | 100.0% | 100.0% |
| 4397665 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 49.0 | 4.96e-01 | 99.0% | 100.0% |
| 3851383 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.56 | 41.0 | 2.93e-01 | 77.6% | 39.7% |
| 3927781 | 3065.1.1.2 ↗ | alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Gp-FAR-1 | 0.56 | 48.0 | 3.96e-01 | 94.9% | 72.2% |
| 4114191 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 49.0 | 4.82e-01 | 100.0% | 100.0% |
| 4032165 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 49.0 | 4.88e-01 | 98.0% | 100.0% |
| 4074458 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 48.0 | 4.81e-01 | 98.0% | 100.0% |
| 4304767 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 49.0 | 4.87e-01 | 99.0% | 100.0% |
| 4176312 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 48.0 | 4.81e-01 | 99.0% | 100.0% |
| 4422869 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 46.0 | 4.66e-01 | 95.9% | 100.0% |
| 3492075 | 3729.1.1.1 ↗ | alpha arrays › Legumain prodomain › Legumain prodomain › Legumain prodomain › Legum_prodom | 0.55 | 41.0 | 3.84e-01 | 80.6% | 94.4% |
| 4266510 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.55 | 48.0 | 4.76e-01 | 100.0% | 100.0% |
| 4363487 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 46.0 | 4.62e-01 | 95.9% | 100.0% |
| 4345287 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 47.0 | 4.73e-01 | 98.0% | 100.0% |
| 3209515 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.54 | 30.0 | 3.44e-01 | 95.9% | 70.7% |
| 4066758 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 46.0 | 4.60e-01 | 94.9% | 100.0% |
| 4042986 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 47.0 | 4.71e-01 | 99.0% | 99.0% |
| 4249652 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 46.0 | 4.66e-01 | 98.0% | 100.0% |
| 4479516 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.53 | 45.0 | 4.54e-01 | 94.9% | 100.0% |
| 3510392 | 6157.1.1.1 ↗ | alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP | 0.53 | 42.0 | 4.08e-01 | 91.8% | 77.3% |
| 4136151 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.52 | 46.0 | 4.58e-01 | 99.0% | 100.0% |
| 4319295 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.52 | 46.0 | 4.56e-01 | 100.0% | 97.1% |
| 3825041 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.52 | 29.0 | 3.01e-01 | 96.9% | 54.7% |
| 3661727 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 40.0 | 3.16e-01 | 92.9% | 39.5% |
| 4221982 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.51 | 43.0 | 4.37e-01 | 95.9% | 100.0% |
| 4223425 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.50 | 43.0 | 4.28e-01 | 96.9% | 96.2% |