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MK448474.1__QBX09997.1__JavanS402_0019__00019
Bact-VirMK448474.1__QBX09997.1__JavanS402_0019__00019
Identity
- Accession:
- MK448474 ↗
- Kingdom:
- phage
Quality
86.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-139
Domain cluster:
representative
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.80 | 63.0 | 6.82e-01 | 97.8% | 97.4% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.79 | 64.0 | 6.65e-01 | 92.8% | 90.7% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.78 | 64.0 | 6.00e-01 | 100.0% | 71.7% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.78 | 58.0 | 5.99e-01 | 98.6% | 80.5% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.77 | 58.0 | 6.37e-01 | 97.1% | 95.5% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.75 | 60.0 | 5.89e-01 | 99.3% | 77.5% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.74 | 54.0 | 5.51e-01 | 97.8% | 77.4% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.74 | 56.0 | 5.78e-01 | 96.4% | 82.7% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.73 | 68.0 | 6.24e-01 | 100.0% | 88.1% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.73 | 56.0 | 6.16e-01 | 100.0% | 99.1% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.73 | 65.0 | 5.86e-01 | 95.7% | 72.3% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 65.0 | 4.95e-01 | 98.6% | 86.5% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.71 | 53.0 | 5.03e-01 | 76.3% | 85.1% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.71 | 65.0 | 5.88e-01 | 100.0% | 89.4% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.71 | 52.0 | 5.83e-01 | 97.8% | 100.0% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.71 | 52.0 | 4.71e-01 | 76.3% | 82.3% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.71 | 53.0 | 5.43e-01 | 97.8% | 82.4% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 54.0 | 4.38e-01 | 79.1% | 81.5% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 53.0 | 4.27e-01 | 80.6% | 86.5% |
| 1yfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.69 | 63.0 | 5.08e-01 | 100.0% | 70.6% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.68 | 41.0 | 4.30e-01 | 87.8% | 64.3% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.68 | 47.0 | 5.05e-01 | 77.0% | 82.9% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 62.0 | 5.33e-01 | 100.0% | 64.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 56.0 | 5.84e-01 | 97.8% | 95.4% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.66 | 56.0 | 5.05e-01 | 100.0% | 67.4% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 58.0 | 4.64e-01 | 100.0% | 48.7% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 52.0 | 4.71e-01 | 84.2% | 70.7% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.65 | 58.0 | 4.42e-01 | 97.8% | 77.9% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.65 | 45.0 | 4.65e-01 | 72.7% | 73.3% |
| 7e84A02 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.64 | 53.0 | 5.35e-01 | 100.0% | 87.8% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.63 | 55.0 | 4.69e-01 | 93.5% | 87.9% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 44.0 | 4.38e-01 | 77.0% | 69.7% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 56.0 | 4.41e-01 | 100.0% | 82.5% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.62 | 54.0 | 4.22e-01 | 95.7% | 71.9% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 57.0 | 4.96e-01 | 100.0% | 85.4% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.61 | 43.0 | 4.18e-01 | 72.7% | 84.7% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.61 | 53.0 | 5.39e-01 | 94.2% | 100.0% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.61 | 47.0 | 4.40e-01 | 82.0% | 67.1% |
| 3r6nA02 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 42.0 | 4.08e-01 | 70.5% | 78.7% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.60 | 52.0 | 5.13e-01 | 98.6% | 89.8% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.59 | 48.0 | 4.72e-01 | 86.3% | 97.3% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 51.0 | 4.38e-01 | 97.8% | 82.4% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 42.0 | 4.55e-01 | 77.0% | 90.6% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 38.0 | 4.16e-01 | 79.1% | 83.6% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.57 | 50.0 | 4.22e-01 | 94.2% | 79.6% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 42.0 | 4.45e-01 | 99.3% | 92.7% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 42.0 | 4.40e-01 | 92.1% | 100.0% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.51 | 44.0 | 3.97e-01 | 93.5% | 73.2% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3251836 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.84 | 69.0 | 7.14e-01 | 97.8% | 91.5% |
| 3385593 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.78 | 66.0 | 6.90e-01 | 100.0% | 99.2% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.77 | 60.0 | 6.15e-01 | 97.8% | 83.7% |
| 3451847 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 70.0 | 6.36e-01 | 98.6% | 86.1% |
| 3864448 | 192.29.1.7 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM192 | 0.76 | 68.0 | 6.32e-01 | 95.0% | 84.1% |
| 3239921 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 68.0 | 6.36e-01 | 95.7% | 84.8% |
| 3587850 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 70.0 | 7.07e-01 | 100.0% | 99.3% |
| 2801375 | 5069.1.1.5 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II | 0.74 | 63.0 | 6.01e-01 | 100.0% | 78.8% |
| 4013887 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.74 | 60.0 | 5.99e-01 | 95.7% | 83.6% |
| 3943911 | 192.29.1.3 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › YliH | 0.74 | 61.0 | 6.49e-01 | 100.0% | 99.2% |
| 4441744 | 601.4.1.78 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DAHL | 0.74 | 59.0 | 6.15e-01 | 98.6% | 90.8% |
| 3217635 | 3684.1.1.30 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 | 0.74 | 63.0 | 5.89e-01 | 100.0% | 74.7% |
| 4565794 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.73 | 68.0 | 6.85e-01 | 100.0% | 99.3% |
| 3385460 | 5069.1.1.74 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › UPF0093 | 0.73 | 66.0 | 6.43e-01 | 100.0% | 90.0% |
| 4963908 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.73 | 67.0 | 6.69e-01 | 100.0% | 97.2% |
| 3391109 | 3684.1.1.21 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 | 0.71 | 64.0 | 6.43e-01 | 100.0% | 95.7% |
| 3239357 | 192.29.1.51 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM138 | 0.71 | 62.0 | 6.26e-01 | 97.8% | 93.6% |
| 3509455 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 64.0 | 6.03e-01 | 97.8% | 90.8% |
| 3952765 | 192.29.1.179 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF26307 | 0.70 | 64.0 | 6.30e-01 | 97.8% | 93.8% |
| 3514283 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 63.0 | 6.12e-01 | 100.0% | 91.0% |
| 3583915 | 192.29.1.51 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM138 | 0.69 | 59.0 | 5.91e-01 | 97.8% | 91.4% |
| 3570028 | 904.1.1.0 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain | 0.69 | 53.0 | 4.89e-01 | 80.6% | 92.0% |
| 4026713 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.69 | 62.0 | 5.73e-01 | 97.8% | 94.3% |
| 3831657 | 145.1.1.58 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › Chloroplast_duf | 0.68 | 60.0 | 5.81e-01 | 95.0% | 89.7% |
| 3691781 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.68 | 62.0 | 5.48e-01 | 100.0% | 73.5% |
| 3286347 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.67 | 52.0 | 4.96e-01 | 92.1% | 69.9% |
| 3932199 | 5001.1.1.69 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd | 0.66 | 59.0 | 4.49e-01 | 97.8% | 80.3% |
| 3468403 | 601.1.2.74 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N | 0.66 | 48.0 | 4.94e-01 | 76.3% | 80.0% |
| 3243154 | 5001.1.1.59 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sri | 0.65 | 59.0 | 4.54e-01 | 98.6% | 80.3% |
| 3281928 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.65 | 53.0 | 5.19e-01 | 97.8% | 79.9% |
| 5068463 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.65 | 49.0 | 4.41e-01 | 77.7% | 90.8% |
| 3927845 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 48.0 | 4.99e-01 | 97.8% | 86.2% |
| 3848467 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.63 | 58.0 | 4.39e-01 | 100.0% | 72.8% |
| 5075236 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 45.0 | 4.81e-01 | 80.6% | 85.8% |
| 3877306 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.62 | 50.0 | 4.66e-01 | 100.0% | 69.1% |
| 3243125 | 5001.1.1.59 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sri | 0.61 | 56.0 | 4.27e-01 | 99.3% | 54.4% |
| 3512307 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.61 | 43.0 | 4.16e-01 | 72.7% | 68.8% |
| 3862009 | 3755.3.1.293 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH | 0.60 | 46.0 | 4.39e-01 | 79.1% | 98.8% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 47.0 | 5.00e-01 | 89.2% | 92.0% |
| 3505857 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.60 | 47.0 | 4.71e-01 | 93.5% | 80.0% |
| 3447256 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.60 | 46.0 | 3.82e-01 | 79.9% | 46.5% |
| 3235605 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 54.0 | 4.43e-01 | 100.0% | 63.2% |
| 3215358 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 46.0 | 4.11e-01 | 93.5% | 95.5% |
| 5055160 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 48.0 | 4.67e-01 | 99.3% | 93.5% |
D2
medium
residues 140-194
Domain cluster:
representative
CATH (51)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.87 | 66.0 | 6.38e-01 | 87.3% | 72.6% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.87 | 70.0 | 6.63e-01 | 87.3% | 89.1% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.80 | 63.0 | 5.73e-01 | 87.3% | 76.3% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.80 | 64.0 | 4.99e-01 | 87.3% | 44.0% |
| 1grjA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.80 | 64.0 | 5.78e-01 | 87.3% | 68.9% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.80 | 70.0 | 5.53e-01 | 100.0% | 87.6% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 63.0 | 5.57e-01 | 87.3% | 62.5% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.79 | 70.0 | 4.96e-01 | 100.0% | 42.8% |
| 3c8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.78 | 62.0 | 4.42e-01 | 87.3% | 32.5% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 62.0 | 6.45e-01 | 89.1% | 100.0% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 61.0 | 5.58e-01 | 87.3% | 68.5% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.77 | 59.0 | 5.78e-01 | 83.6% | 84.7% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.77 | 67.0 | 5.45e-01 | 98.2% | 93.1% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.77 | 60.0 | 5.38e-01 | 87.3% | 100.0% |
| 3b2eF00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 60.0 | 5.82e-01 | 87.3% | 77.4% |
| 7nc3F01 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.76 | 60.0 | 4.73e-01 | 87.3% | 44.7% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.76 | 60.0 | 5.77e-01 | 89.1% | 76.2% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 59.0 | 4.94e-01 | 87.3% | 58.6% |
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.76 | 58.0 | 5.40e-01 | 85.5% | 93.0% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.76 | 59.0 | 5.18e-01 | 87.3% | 59.5% |
| 2pybA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 61.0 | 4.40e-01 | 89.1% | 32.5% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.75 | 57.0 | 5.94e-01 | 85.5% | 90.2% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.75 | 58.0 | 6.04e-01 | 85.5% | 94.0% |
| 1ucuA01 | 6.10.280.190 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 58.0 | 5.49e-01 | 87.3% | 79.4% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.73 | 56.0 | 4.91e-01 | 89.1% | 54.7% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.73 | 61.0 | 5.13e-01 | 100.0% | 96.1% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.73 | 55.0 | 5.47e-01 | 89.1% | 82.1% |
| 2lf0A01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.72 | 54.0 | 5.34e-01 | 87.3% | 76.7% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.72 | 56.0 | 5.41e-01 | 87.3% | 82.8% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 56.0 | 5.55e-01 | 87.3% | 100.0% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 58.0 | 4.53e-01 | 90.9% | 75.8% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 56.0 | 4.96e-01 | 89.1% | 59.0% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.71 | 55.0 | 5.63e-01 | 83.6% | 88.5% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 56.0 | 4.65e-01 | 89.1% | 48.0% |
| 6qs7C01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 53.0 | 4.13e-01 | 92.7% | 35.6% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.71 | 54.0 | 4.27e-01 | 87.3% | 38.7% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 58.0 | 3.95e-01 | 100.0% | 55.2% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.66 | 55.0 | 4.77e-01 | 100.0% | 68.5% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.65 | 50.0 | 4.03e-01 | 83.6% | 58.0% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.65 | 48.0 | 4.70e-01 | 83.6% | 77.8% |
| 1luwA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.65 | 50.0 | 4.85e-01 | 89.1% | 81.2% |
| 4hxiB03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.65 | 46.0 | 3.82e-01 | 76.4% | 47.5% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 50.0 | 4.90e-01 | 87.3% | 86.9% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.63 | 47.0 | 4.49e-01 | 87.3% | 70.0% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 52.0 | 4.77e-01 | 92.7% | 86.5% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 47.0 | 4.86e-01 | 81.8% | 100.0% |
| 1ywmA02 | 1.20.1270.150 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Surface Active Protein | 0.62 | 50.0 | 4.68e-01 | 100.0% | 71.1% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.60 | 47.0 | 4.76e-01 | 87.3% | 89.3% |
| 5jxxA02 | 1.20.1180.10 | Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain | 0.58 | 47.0 | 4.48e-01 | 96.4% | 75.8% |
| 2g8lB01 | 1.10.8.380 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 | 0.55 | 46.0 | 4.35e-01 | 96.4% | 77.6% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.53 | 47.0 | 3.30e-01 | 100.0% | 85.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5057802 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.86 | 72.0 | 5.24e-01 | 89.1% | 36.3% |
| 3180581 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.85 | 68.0 | 5.86e-01 | 87.3% | 63.5% |
| 4051951 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.82 | 65.0 | 5.52e-01 | 87.3% | 74.4% |
| 3278180 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.81 | 65.0 | 3.69e-01 | 87.3% | 9.3% |
| 3396783 | 4207.1.2.54 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › THOC7 | 0.80 | 62.0 | 4.77e-01 | 85.5% | 40.8% |
| 4652719 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.80 | 64.0 | 5.31e-01 | 87.3% | 76.8% |
| 3989824 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.79 | 61.0 | 6.38e-01 | 87.3% | 94.0% |
| 4935068 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.79 | 64.0 | 5.77e-01 | 89.1% | 77.3% |
| 2141223 | 5055.1.1.1 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel › CaMBD | 0.78 | 62.0 | 5.19e-01 | 87.3% | 52.6% |
| 3348910 | 192.1.1.46 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF3475 | 0.78 | 64.0 | 4.30e-01 | 90.9% | 81.5% |
| 4530141 | 192.11.1.1 ↗ | alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › UVR | 0.78 | 60.0 | 6.26e-01 | 87.3% | 94.0% |
| 3957407 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.77 | 53.0 | 3.34e-01 | 87.3% | 14.5% |
| 4939264 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.77 | 61.0 | 5.69e-01 | 89.1% | 77.1% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.77 | 58.0 | 5.40e-01 | 83.6% | 75.7% |
| 4838801 | 3710.1.1.1 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 | 0.74 | 58.0 | 5.59e-01 | 87.3% | 73.8% |
| 3962893 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.73 | 58.0 | 4.88e-01 | 89.1% | 62.1% |
| 3705127 | 509.1.1.0 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain | 0.73 | 63.0 | 5.31e-01 | 100.0% | 61.1% |
| 3204106 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.71 | 61.0 | 5.51e-01 | 100.0% | 75.0% |
| 5055769 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 54.0 | 4.90e-01 | 87.3% | 73.8% |
| 3663990 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.71 | 54.0 | 5.13e-01 | 87.3% | 77.1% |
| 3718753 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.70 | 55.0 | 4.50e-01 | 87.3% | 51.4% |
| 3497251 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.69 | 59.0 | 5.25e-01 | 100.0% | 67.5% |
| 3880111 | 4082.1.1.1 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange | 0.69 | 51.0 | 5.48e-01 | 87.3% | 97.8% |
| 3757869 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.66 | 55.0 | 4.72e-01 | 98.2% | 83.2% |
| 4940728 | 614.1.1.0 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain | 0.66 | 53.0 | 5.52e-01 | 90.9% | 100.0% |
| 3746144 | 192.29.1.273 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › NICE-3 | 0.65 | 54.0 | 5.23e-01 | 100.0% | 89.2% |
| 3399070 | 4082.1.1.1 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange | 0.64 | 52.0 | 5.29e-01 | 90.9% | 94.5% |
| 3754265 | 603.1.1.187 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DNA_repr_REX1B | 0.63 | 47.0 | 4.24e-01 | 89.1% | 57.8% |
| 3447292 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.63 | 44.0 | 4.75e-01 | 96.4% | 88.9% |
| 3008264 | 5073.1.1.4 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C,Cation_ATPase_N | 0.62 | 51.0 | 4.00e-01 | 96.4% | 41.9% |
| 4663861 | 5069.1.3.78 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MIS13 | 0.59 | 46.0 | 4.20e-01 | 92.7% | 75.0% |
| 4451187 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.55 | 46.0 | 4.43e-01 | 98.2% | 83.1% |