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MK448650.1__QBX13350.1__JavanS761_0021__00021

Bact-Vir

MK448650.1__QBX13350.1__JavanS761_0021__00021

Identity

Accession:
MK448650 ↗
Kingdom:
phage

Quality

80.5 mean pLDDT

Taxonomy

TaxID: 2558857

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 28-100
PDB
Domain cluster: representative
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.89 68.0 6.74e-01 79.5% 80.3%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.86 69.0 7.07e-01 84.9% 94.4%
1kvkA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.85 63.0 4.84e-01 76.7% 37.8%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 75.0 7.53e-01 94.5% 100.0%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.84 77.0 6.79e-01 98.6% 95.1%
2c2aA01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.84 70.0 6.49e-01 89.0% 80.0%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 67.0 6.64e-01 84.9% 80.5%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.84 72.0 5.06e-01 100.0% 31.8%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.84 75.0 5.89e-01 95.9% 64.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.83 73.0 6.49e-01 94.5% 76.5%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.83 65.0 6.05e-01 94.5% 67.0%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 66.0 7.07e-01 94.5% 98.4%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.83 73.0 5.94e-01 94.5% 70.0%
4kzsA02 6.10.140.1870 Special › Helix non-globular › Helix Hairpins › 0.82 60.0 6.16e-01 78.1% 80.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 74.0 7.17e-01 100.0% 93.8%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 70.0 6.90e-01 93.2% 88.3%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.81 70.0 5.22e-01 94.5% 40.6%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 69.0 7.03e-01 97.3% 94.4%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.80 70.0 5.65e-01 94.5% 54.1%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 69.0 7.10e-01 100.0% 98.6%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 60.0 6.37e-01 78.1% 96.9%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 69.0 7.03e-01 94.5% 100.0%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.79 68.0 6.62e-01 91.8% 92.5%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.79 71.0 5.81e-01 100.0% 63.2%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.79 51.0 4.30e-01 74.0% 41.4%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.79 70.0 6.94e-01 98.6% 93.5%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.79 63.0 5.83e-01 97.3% 68.1%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 69.0 4.83e-01 95.9% 31.5%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 64.0 6.42e-01 90.4% 87.7%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 70.0 4.77e-01 100.0% 29.8%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.78 69.0 5.90e-01 100.0% 66.4%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 64.0 6.60e-01 90.4% 100.0%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.77 68.0 5.73e-01 100.0% 70.4%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.77 56.0 5.97e-01 82.2% 90.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.77 69.0 6.45e-01 98.6% 87.8%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 68.0 6.05e-01 100.0% 81.0%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.76 61.0 5.95e-01 93.2% 78.0%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 60.0 6.23e-01 86.3% 100.0%
4i1mB01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.76 60.0 5.02e-01 87.7% 51.2%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.75 66.0 5.27e-01 93.2% 89.5%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.75 67.0 5.98e-01 98.6% 72.5%
7sgrA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.75 66.0 4.34e-01 100.0% 37.4%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.75 65.0 5.37e-01 98.6% 57.1%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 65.0 5.89e-01 100.0% 72.7%
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 62.0 6.16e-01 95.9% 87.0%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 60.0 6.25e-01 90.4% 100.0%
1rv2D04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.74 58.0 5.91e-01 94.5% 88.6%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.73 62.0 5.57e-01 100.0% 67.3%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.73 65.0 5.92e-01 100.0% 83.7%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.73 55.0 5.31e-01 86.3% 71.4%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 58.0 4.94e-01 100.0% 52.8%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.72 61.0 6.22e-01 93.2% 97.2%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.72 63.0 6.25e-01 100.0% 96.2%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.72 52.0 3.87e-01 78.1% 30.3%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.72 63.0 4.84e-01 98.6% 56.7%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.71 64.0 5.29e-01 97.3% 88.8%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.71 61.0 5.84e-01 94.5% 87.1%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.71 46.0 5.22e-01 71.2% 96.1%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.71 61.0 4.92e-01 98.6% 49.0%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.71 52.0 4.83e-01 80.8% 60.8%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.70 63.0 5.93e-01 100.0% 88.8%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.70 60.0 5.41e-01 100.0% 71.7%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 56.0 4.79e-01 90.4% 81.5%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 60.0 5.41e-01 100.0% 70.3%
7lb8B01 1.10.3470.10 Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC 0.69 63.0 4.06e-01 100.0% 76.3%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 54.0 5.74e-01 89.0% 100.0%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.66 57.0 4.66e-01 94.5% 51.1%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.65 56.0 4.95e-01 91.8% 93.0%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 53.0 4.89e-01 94.5% 70.1%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.64 50.0 4.46e-01 90.4% 58.4%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.62 48.0 4.02e-01 82.2% 91.1%
8hdlA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 53.0 3.74e-01 98.6% 49.4%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 49.0 4.97e-01 94.5% 91.9%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3174178 632.22.1.153 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › AIP3 0.89 82.0 6.04e-01 100.0% 47.4%
4652719 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.87 73.0 6.57e-01 87.7% 92.6%
3934830 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.87 76.0 7.32e-01 91.8% 85.0%
3768858 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.87 73.0 6.61e-01 89.0% 69.5%
3401938 3602.1.1.14 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › DUF733 0.86 71.0 7.11e-01 87.7% 85.3%
3595002 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.86 73.0 6.43e-01 89.0% 87.0%
4942789 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.86 79.0 6.27e-01 100.0% 58.6%
3737505 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.85 77.0 7.63e-01 95.9% 100.0%
5064482 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 80.0 5.96e-01 100.0% 60.6%
3594486 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 78.0 6.50e-01 98.6% 67.5%
3516570 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.85 75.0 7.26e-01 93.2% 86.3%
3766572 4177.1.1.112 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › bMERB_dom 0.85 76.0 5.62e-01 94.5% 74.6%
3400926 3758.1.1.45 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Not3 0.85 77.0 6.44e-01 95.9% 61.7%
3239791 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 79.0 5.77e-01 100.0% 41.7%
3412574 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.85 75.0 6.08e-01 94.5% 60.0%
3271624 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.84 78.0 4.72e-01 100.0% 17.2%
3269107 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.84 76.0 5.43e-01 100.0% 36.6%
5031890 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 78.0 5.24e-01 100.0% 33.5%
3585224 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.84 73.0 6.94e-01 93.2% 81.2%
3432902 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.84 76.0 6.50e-01 100.0% 64.3%
3460130 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.84 65.0 6.33e-01 89.0% 75.0%
3553833 5086.1.1.102 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp 0.83 77.0 5.56e-01 100.0% 43.2%
3388215 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 75.0 5.73e-01 100.0% 45.5%
5054469 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.83 77.0 6.71e-01 100.0% 94.3%
3786359 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.83 77.0 6.86e-01 100.0% 75.0%
3529043 3922.1.1.179 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › bMERB_dom 0.83 77.0 5.64e-01 100.0% 49.4%
3853458 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.83 72.0 6.55e-01 93.2% 71.6%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.83 75.0 6.65e-01 100.0% 71.0%
4998774 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.83 77.0 4.59e-01 100.0% 15.9%
3999274 5086.1.1.102 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp 0.82 72.0 6.26e-01 100.0% 64.8%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.82 72.0 7.39e-01 95.9% 100.0%
4162727 5086.1.1.12 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 0.81 71.0 5.58e-01 94.5% 64.1%
4026684 192.20.1.7 alpha bundles › Long alpha-hairpin › helical hairpin domain in transcriptional anti-activator ExsD › helical hairpin domain in transcriptional anti-activator ExsD › PF26729 0.81 75.0 6.54e-01 100.0% 70.5%
3499411 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.81 75.0 4.40e-01 100.0% 48.8%
4784164 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 70.0 7.21e-01 94.5% 98.6%
5025381 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.81 74.0 4.73e-01 100.0% 24.8%
3853063 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.81 74.0 6.22e-01 100.0% 62.5%
3215082 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.80 73.0 5.90e-01 100.0% 59.3%
3494796 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.80 72.0 4.82e-01 100.0% 28.5%
5079778 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.80 74.0 4.43e-01 100.0% 16.7%
3231580 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.80 73.0 4.94e-01 100.0% 31.6%
3784740 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.80 67.0 6.72e-01 100.0% 88.0%
3473220 5086.1.1.209 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LIN9_C 0.80 73.0 6.23e-01 100.0% 71.3%
3772767 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.80 70.0 5.76e-01 94.5% 84.0%
3553813 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.80 70.0 5.74e-01 94.5% 84.0%
3163896 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.79 74.0 5.18e-01 100.0% 50.0%
4086322 5086.1.1.205 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF30209 0.79 71.0 5.44e-01 100.0% 46.1%
3503444 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.79 70.0 6.56e-01 98.6% 80.0%
3170937 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.79 70.0 4.70e-01 100.0% 27.6%
4809272 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.79 70.0 5.94e-01 100.0% 90.9%
3491418 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.78 68.0 6.76e-01 95.9% 93.3%
4247116 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.78 68.0 5.98e-01 100.0% 65.5%
3752758 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.78 70.0 5.51e-01 100.0% 51.0%
5002089 2004.1.1.144 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.78 72.0 4.61e-01 100.0% 33.3%
4303085 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.78 70.0 5.90e-01 100.0% 63.3%
4051951 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.78 66.0 6.22e-01 95.9% 97.8%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 68.0 6.54e-01 100.0% 88.2%
315449 192.8.1.2 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Hanta_nucleocap 0.77 68.0 6.78e-01 97.3% 96.1%
3487862 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.77 69.0 4.76e-01 100.0% 30.8%
4798159 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 68.0 6.76e-01 98.6% 94.7%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 68.0 6.50e-01 100.0% 88.2%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.77 68.0 6.50e-01 100.0% 87.1%
3945620 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.77 68.0 6.34e-01 100.0% 80.0%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.76 67.0 4.74e-01 100.0% 33.0%
3596479 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.76 66.0 5.41e-01 100.0% 53.1%
4946656 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 64.0 5.44e-01 94.5% 76.7%
3612915 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 66.0 5.87e-01 100.0% 68.6%
3916497 632.8.1.17 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Rab_eff_C 0.74 65.0 5.49e-01 100.0% 59.2%
3577239 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 65.0 4.56e-01 100.0% 31.7%
3626769 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.73 63.0 5.96e-01 100.0% 83.3%
4080313 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.73 64.0 5.21e-01 100.0% 70.7%
3585209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 63.0 5.19e-01 100.0% 54.1%
3437997 148.1.3.204 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › UVR, AAA_lid_9 0.71 59.0 4.69e-01 93.2% 47.1%
4225217 3710.1.1.1 alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5 0.70 61.0 5.36e-01 98.6% 69.1%
3638319 192.7.1.56 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › CHD5 0.69 59.0 5.45e-01 100.0% 78.0%
D2 high residues 106-211
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 36.0 4.25e-01 71.7% 66.7%
2kc7A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 34.0 3.56e-01 82.1% 49.5%
1oqyA03 1.10.10.540 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › XPC-binding domain 0.66 37.0 4.71e-01 100.0% 100.0%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 39.0 4.60e-01 85.8% 84.0%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.65 58.0 5.37e-01 97.2% 75.9%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 53.0 5.06e-01 96.2% 77.5%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.63 42.0 4.21e-01 100.0% 66.1%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.62 43.0 4.69e-01 95.3% 88.4%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.61 56.0 4.67e-01 99.1% 65.7%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.61 52.0 4.33e-01 91.5% 70.6%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 52.0 4.84e-01 96.2% 80.5%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 49.0 3.88e-01 97.2% 98.7%
4o7oA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.55 47.0 3.66e-01 95.3% 94.1%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.54 47.0 4.00e-01 96.2% 68.2%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 43.0 4.36e-01 97.2% 87.2%
1j09A05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.53 40.0 4.13e-01 100.0% 84.7%
4dvyP01 1.10.357.130 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.53 44.0 3.57e-01 88.7% 70.1%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.53 34.0 3.74e-01 92.5% 79.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 42.0 4.24e-01 89.6% 86.9%
3cqyB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 46.0 3.78e-01 96.2% 58.2%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3937171 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 45.0 3.96e-01 84.9% 47.7%
4023423 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.62 57.0 4.66e-01 96.2% 62.2%
3248447 5054.1.1.9 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel 0.62 56.0 3.95e-01 100.0% 46.3%
3283147 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.59 49.0 3.74e-01 92.5% 44.2%
4513616 3198.1.1.1 alpha bundles › ABA-1 repeat unit › ABA-1 repeat unit › ABA-1 repeat unit › NPA 0.58 37.0 3.48e-01 90.6% 51.5%
3978383 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.58 52.0 4.34e-01 99.1% 80.5%
4930182 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.57 46.0 3.73e-01 84.9% 74.4%
3590772 6152.1.1.1 alpha arrays › Helical domain in Orf11 › Helical domain in Orf11 › Helical domain in Orf11 › NAT_N 0.57 42.0 4.30e-01 95.3% 81.0%
4030773 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.55 49.0 3.82e-01 99.1% 68.5%
4943050 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.53 43.0 3.12e-01 87.7% 80.7%
3714237 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.51 37.0 3.80e-01 94.3% 76.2%
3601490 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.51 36.0 3.24e-01 72.6% 76.6%
3243556 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 39.0 3.25e-01 87.7% 43.9%
3754401 109.26.1.1 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.50 40.0 2.60e-01 85.8% 26.1%