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MK448890.1__QBX25549.1__Javan264_0001__00001

Bact-Vir

MK448890.1__QBX25549.1__Javan264_0001__00001

Identity

Accession:
MK448890 ↗
Kingdom:
phage

Quality

89.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-58
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.74 59.0 5.35e-01 91.2% 64.6%
3ecrB03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.73 63.0 5.18e-01 96.5% 66.7%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.73 50.0 4.84e-01 84.2% 63.1%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.72 60.0 5.24e-01 100.0% 61.6%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.71 58.0 5.80e-01 91.2% 88.3%
4g3vA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.71 60.0 4.43e-01 100.0% 45.7%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 57.0 5.29e-01 98.2% 73.0%
6u5uG07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.66 45.0 3.43e-01 71.9% 33.3%
6u5vB07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.66 45.0 3.44e-01 71.9% 34.1%
1stzA02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.65 57.0 4.26e-01 100.0% 44.3%
3j7aV00 2.40.50.1000 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.65 46.0 3.46e-01 75.4% 44.5%
5c0pA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.64 46.0 2.93e-01 87.7% 15.1%
1pguA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.64 44.0 2.77e-01 73.7% 21.6%
4bs9A05 3.30.160.660 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.63 52.0 4.34e-01 100.0% 53.5%
2hqlA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.63 46.0 4.04e-01 80.7% 60.4%
3ebwA01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.63 49.0 3.66e-01 84.2% 45.8%
2uvaG07 3.30.1120.100 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.63 43.0 3.28e-01 71.9% 32.4%
1qwdB00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.62 46.0 3.40e-01 82.5% 45.2%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.61 42.0 3.90e-01 84.2% 54.5%
2x8fA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.61 53.0 3.30e-01 98.2% 20.0%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.61 50.0 3.97e-01 96.5% 43.2%
2ex2A01 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.60 50.0 3.41e-01 100.0% 24.1%
2qsdA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 41.0 3.99e-01 77.2% 64.2%
2i1yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.59 51.0 3.22e-01 96.5% 72.5%
3pnrA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.58 43.0 2.88e-01 80.7% 83.3%
4a55A01 3.10.20.770 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.58 44.0 2.90e-01 91.2% 16.5%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 42.0 3.06e-01 78.9% 39.9%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.58 35.0 3.04e-01 71.9% 37.0%
3hhmA03 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.57 44.0 3.48e-01 91.2% 36.2%
3iwgA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.56 47.0 3.57e-01 93.0% 63.0%
2bjoA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.56 39.0 3.30e-01 71.9% 79.8%
4q8gA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 49.0 3.07e-01 100.0% 27.0%
7szeB02 3.90.380.10 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 0.56 48.0 3.45e-01 100.0% 78.8%
4gzvA00 2.40.128.490 Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein PF14869 family, DUF4488 0.56 40.0 3.14e-01 93.0% 33.1%
1x67A01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.56 40.0 3.19e-01 89.5% 34.6%
1dzkA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 41.0 3.08e-01 80.7% 86.5%
2kt4B01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 40.0 3.17e-01 84.2% 50.7%
2r39A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 45.0 3.81e-01 100.0% 76.1%
4dy0B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.54 48.0 3.71e-01 100.0% 59.4%
1vkcA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 45.0 3.46e-01 93.0% 76.3%
1oi2A02 3.30.1180.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › Dihydroxyacetone kinase; domain 2 0.54 46.0 3.35e-01 96.5% 69.1%
2kczA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 41.0 3.07e-01 86.0% 93.5%
4aqsA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.53 39.0 2.67e-01 82.5% 62.9%
1t3yA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.53 44.0 3.51e-01 100.0% 81.7%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 36.0 2.56e-01 70.2% 56.0%
2joqA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.53 38.0 3.65e-01 82.5% 92.0%
1cjxB02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.53 46.0 3.22e-01 100.0% 94.1%
3o2iA00 3.30.70.2710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 39.0 3.44e-01 82.5% 57.0%
1fl7D00 2.10.90.10 Mainly Beta › Ribbon › Cystine Knot Cytokines, subunit B › Cystine-knot cytokines 0.53 41.0 3.41e-01 87.7% 58.5%
8jx6A02 2.30.30.780 Mainly Beta › Roll › SH3 type barrels. › 0.53 40.0 3.32e-01 84.2% 72.8%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 35.0 3.37e-01 96.5% 58.0%
5a2fA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 42.0 3.50e-01 98.2% 80.4%
4oddA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 38.0 3.00e-01 89.5% 44.3%
3rhtA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.50 41.0 2.72e-01 91.2% 96.4%
ECOD (79)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5050683 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.80 67.0 5.15e-01 100.0% 42.4%
4058654 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.79 68.0 5.59e-01 96.5% 54.5%
4214888 330.3.1.1 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like › RF-1 0.75 66.0 5.48e-01 100.0% 71.0%
222972 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.74 59.0 5.14e-01 91.2% 57.3%
4120507 292.2.1.1 a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › POLO_box 0.73 48.0 4.07e-01 73.7% 41.1%
3937984 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.73 64.0 5.27e-01 100.0% 55.0%
5053632 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.73 63.0 4.97e-01 100.0% 46.4%
4524129 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 63.0 5.40e-01 100.0% 63.2%
3194095 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.73 65.0 5.46e-01 100.0% 62.1%
4985406 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.73 49.0 4.37e-01 70.2% 100.0%
3588192 4325.1.1.7 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › Arm-DNA-bind_4 0.72 57.0 6.04e-01 89.5% 100.0%
4054729 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.72 59.0 5.43e-01 96.5% 69.3%
3992783 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.72 52.0 3.36e-01 75.4% 18.8%
4971888 512.1.1.1 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.72 63.0 4.17e-01 100.0% 30.9%
3472467 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.72 59.0 5.39e-01 91.2% 70.7%
4216680 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.72 57.0 4.86e-01 96.5% 53.8%
3404964 221.13.1.0 a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.71 62.0 4.96e-01 100.0% 49.6%
3924626 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.70 59.0 5.22e-01 100.0% 64.7%
3780194 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.70 60.0 3.91e-01 100.0% 22.4%
4043415 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 60.0 3.52e-01 100.0% 12.0%
3235699 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 59.0 4.73e-01 100.0% 47.8%
3585861 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 60.0 4.48e-01 100.0% 39.3%
4297447 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 59.0 4.47e-01 100.0% 39.3%
4929017 1.1.2.0 beta barrels › cradle loop barrel › RIFT-related › double psi 0.69 57.0 4.42e-01 91.2% 96.0%
3565104 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.69 59.0 3.28e-01 100.0% 6.5%
3707615 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.69 59.0 4.27e-01 96.5% 70.0%
3334247 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 60.0 4.90e-01 100.0% 54.5%
3934156 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.69 46.0 3.72e-01 70.2% 41.7%
4928623 1.1.2.16 beta barrels › cradle loop barrel › RIFT-related › double psi › MacB_PCD 0.69 57.0 3.94e-01 91.2% 63.2%
5001130 101.1.2.44 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S25 0.68 46.0 3.82e-01 70.2% 80.0%
3931594 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.67 56.0 4.91e-01 100.0% 61.1%
4027196 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.67 57.0 4.82e-01 100.0% 56.0%
4004011 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.67 56.0 4.65e-01 100.0% 53.6%
5023443 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.65 50.0 4.81e-01 94.7% 73.8%
3639738 2.1.1.6 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.64 49.0 4.66e-01 82.5% 73.1%
5042035 512.1.1.2 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd 0.64 53.0 3.67e-01 100.0% 33.9%
4024738 220.1.1.243 beta barrels › PH domain-like › PH domain-like › PH domain-like › PF30062 0.63 45.0 3.68e-01 75.4% 50.5%
5029914 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.63 49.0 4.99e-01 87.7% 94.5%
4183868 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.62 48.0 4.37e-01 89.5% 62.0%
4036906 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.61 46.0 4.25e-01 91.2% 61.3%
3696336 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 45.0 3.88e-01 80.7% 69.5%
3600626 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 44.0 3.78e-01 80.7% 52.0%
3938203 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.60 52.0 3.25e-01 96.5% 32.6%
4935472 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.60 47.0 4.52e-01 96.5% 75.7%
3058947 221.1.1.8 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PI3K_rbd 0.60 41.0 3.33e-01 77.2% 35.3%
4003909 883.1.1.0 a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like 0.59 46.0 3.31e-01 86.0% 30.9%
3944961 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.59 44.0 3.02e-01 86.0% 33.9%
4020396 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.59 52.0 4.49e-01 98.2% 87.8%
4930552 3501.1.1.0 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.57 52.0 4.62e-01 100.0% 95.0%
3484809 4096.1.1.1 a+b two layers › NAP-like › NAP-like › NAP-like › NAP 0.57 43.0 3.24e-01 80.7% 74.3%
3479746 2007.2.3.0 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II 0.57 49.0 3.10e-01 96.5% 71.5%
3940677 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.57 44.0 3.13e-01 94.7% 25.6%
3412122 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.57 50.0 3.47e-01 100.0% 85.1%
3717169 298.1.1.24 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 0.56 49.0 3.42e-01 100.0% 70.5%
4945668 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.56 44.0 3.34e-01 86.0% 94.3%
4025734 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.56 46.0 3.20e-01 100.0% 24.9%
3238943 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 47.0 2.97e-01 98.2% 30.9%
4025160 2.1.1.6 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.55 44.0 3.49e-01 91.2% 76.0%
4029815 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 39.0 3.11e-01 77.2% 36.9%
3236416 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.55 49.0 3.02e-01 100.0% 29.2%
3193088 246.2.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.55 39.0 2.36e-01 77.2% 15.3%
4213219 109.21.1.0 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain 0.55 46.0 2.53e-01 91.2% 38.7%
3579667 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.54 44.0 3.39e-01 91.2% 50.4%
3212521 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 44.0 2.71e-01 89.5% 66.1%
3722239 2003.1.2.6 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like,NAD_binding_8 0.54 47.0 2.80e-01 98.2% 46.4%
3994884 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.54 44.0 2.83e-01 96.5% 39.4%
5062817 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.53 45.0 3.44e-01 93.0% 100.0%
3740226 5051.1.1.7 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp 0.53 48.0 2.78e-01 98.2% 85.0%
3923319 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.53 43.0 2.94e-01 96.5% 36.2%
5009939 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 46.0 3.72e-01 98.2% 91.4%
3255162 3662.1.1.1 a+b two layers › Proteasome assembling chaperone 3 (PAC3)-related › Proteasome assembling chaperone 3 (PAC3)-related › Proteasome assembling chaperone 3 (PAC3)-related › PAC3 0.51 40.0 3.31e-01 91.2% 67.8%
5051838 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.51 42.0 3.27e-01 94.7% 99.3%
None 0.51 44.0 2.47e-01 96.5% 20.8%
4974067 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.51 43.0 3.19e-01 94.7% 92.9%
4464235 295.1.1.30 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › Cyto_heme_lyase 0.51 39.0 2.93e-01 91.2% 52.8%
3767941 220.1.1.115 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_19 0.51 35.0 2.86e-01 75.4% 51.5%
3228385 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.51 40.0 2.34e-01 91.2% 12.9%
5053463 5.1.5.231 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › SBBP 0.51 42.0 2.78e-01 100.0% 25.6%
4018584 6155.1.1.15 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF846 0.50 46.0 3.34e-01 100.0% 61.3%
D2 high residues 65-144
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14659.13 best Phage_int_SAM_3 31.4 2.60e-07 70.0% 96.5%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2kd1A00 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.86 79.0 6.85e-01 100.0% 70.3%
2kobA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.84 77.0 7.35e-01 100.0% 86.0%
2khvA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.81 74.0 7.30e-01 100.0% 96.5%
1x3kA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.71 51.0 4.18e-01 76.2% 97.3%
1yozA00 1.10.3200.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like 0.64 44.0 3.95e-01 71.2% 68.1%
8cdaC01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.64 45.0 4.01e-01 73.8% 62.4%
5gj7A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.64 44.0 3.84e-01 72.5% 57.6%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 50.0 4.10e-01 87.5% 98.7%
3vibA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 42.0 3.26e-01 77.5% 42.0%
3s6jE02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.56 42.0 4.44e-01 100.0% 92.8%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 38.0 2.66e-01 71.2% 83.8%
6klvB00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.55 41.0 2.71e-01 81.2% 36.7%
4efcA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.55 39.0 4.31e-01 98.8% 98.4%
3ungC04 1.20.120.1260 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-Cas system, Cmr2 subunit, D4 domain, six-helix bundle 0.55 42.0 4.05e-01 92.5% 72.2%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 38.0 3.89e-01 100.0% 77.3%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.54 34.0 3.55e-01 100.0% 69.3%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.54 47.0 3.75e-01 98.8% 80.5%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 41.0 3.65e-01 86.3% 81.1%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.52 42.0 4.09e-01 100.0% 77.3%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 44.0 3.91e-01 96.2% 83.3%
2ra1A02 1.20.58.780 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 38.0 4.03e-01 98.8% 94.1%
7vkcA01 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.51 45.0 3.57e-01 98.8% 76.4%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4663744 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.97 93.0 8.13e-01 100.0% 72.7%
3587101 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.91 86.0 7.71e-01 100.0% 80.0%
4004484 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.91 85.0 7.40e-01 100.0% 83.5%
3964236 186.1.1.8 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_M 0.90 84.0 7.20e-01 100.0% 68.3%
3957640 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.89 83.0 7.62e-01 100.0% 80.0%
3589750 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.89 84.0 7.51e-01 100.0% 76.2%
4009383 186.1.1.3 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_5 0.88 82.0 7.17e-01 100.0% 83.5%
170034 186.1.1.5 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_3 0.86 79.0 7.03e-01 100.0% 75.5%
4004726 186.1.1.8 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_M 0.85 79.0 6.89e-01 100.0% 70.4%
136582 186.1.1.8 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_M 0.84 77.0 7.15e-01 100.0% 80.0%
3839994 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.70 48.0 3.50e-01 71.2% 39.1%
3280266 4033.1.1.1 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.69 48.0 4.23e-01 72.5% 55.8%
4106131 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.66 35.0 3.19e-01 97.5% 40.0%
3807769 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 54.0 5.22e-01 98.8% 83.3%
2114338 4033.1.1.1 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA_dh_N 0.63 43.0 3.81e-01 72.5% 59.0%
3489734 197.1.1.0 alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like 0.62 35.0 3.57e-01 88.7% 55.0%
3941457 1203.1.2.3 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › YiaAB 0.61 51.0 4.50e-01 92.5% 86.7%
3449702 131.1.1.3 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD 0.60 52.0 3.86e-01 100.0% 47.3%
5013474 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.58 43.0 3.16e-01 80.0% 66.4%
4971381 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.58 42.0 3.64e-01 98.8% 49.6%
4575178 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.58 43.0 3.34e-01 96.2% 34.6%
4174856 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.57 42.0 3.04e-01 80.0% 82.4%
4997844 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.57 44.0 3.13e-01 85.0% 56.2%
5037933 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 40.0 2.89e-01 76.2% 44.7%
5060987 5048.1.1.1 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.56 47.0 3.71e-01 97.5% 86.5%
4971189 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.56 42.0 2.97e-01 81.2% 50.0%
3968520 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.55 43.0 3.04e-01 85.0% 49.8%
4887725 2486.1.1.11 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_2 0.55 47.0 3.03e-01 100.0% 31.8%
3173369 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.55 48.0 3.15e-01 97.5% 46.5%
3738358 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 38.0 3.90e-01 100.0% 77.3%
4995732 604.32.1.0 alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY 0.54 37.0 3.09e-01 70.0% 85.7%
3478235 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 44.0 3.83e-01 92.5% 84.4%
3992191 109.4.1.134 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SPIN90_LRD 0.53 36.0 3.37e-01 98.8% 56.0%
3648850 3567.1.1.93 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Tcp11 0.52 47.0 4.05e-01 100.0% 64.8%
4941211 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.52 43.0 3.18e-01 90.0% 83.9%
4971190 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.52 38.0 2.69e-01 78.8% 61.1%
4102866 101.8.1.4 alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › tRNA-synt_1f 0.52 40.0 2.95e-01 91.3% 36.2%
4937939 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.51 38.0 2.90e-01 81.2% 60.3%
3473220 5086.1.1.209 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LIN9_C 0.51 36.0 3.14e-01 100.0% 50.4%
3249530 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.51 40.0 3.46e-01 88.7% 63.0%
3580917 109.27.1.0 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.50 36.0 3.59e-01 77.5% 75.3%
D3 medium residues 165-247
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3nkhA00 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.88 78.0 5.53e-01 94.0% 40.3%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4522024 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.95 84.0 6.64e-01 92.8% 50.7%
3588110 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.90 76.0 6.21e-01 90.4% 52.9%
4659012 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.89 72.0 5.86e-01 94.0% 49.0%
1267972 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.89 76.0 5.93e-01 89.2% 54.1%
3954716 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.86 68.0 5.61e-01 94.0% 49.3%
4034079 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.86 70.0 5.84e-01 98.8% 52.6%
3589779 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.85 71.0 5.69e-01 91.6% 48.7%
4446668 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.85 65.0 5.33e-01 85.5% 47.1%
3588206 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.84 75.0 6.04e-01 98.8% 52.7%
4331898 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.84 61.0 5.92e-01 74.7% 74.4%
4137254 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.84 72.0 5.72e-01 98.8% 49.0%
3589594 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.82 73.0 5.77e-01 97.6% 50.3%
5083074 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.82 68.0 5.53e-01 98.8% 49.3%
4934303 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.82 59.0 6.15e-01 84.3% 80.8%
3289618 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.79 65.0 5.24e-01 89.2% 49.7%
3586881 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.78 63.0 5.13e-01 90.4% 48.0%
4134015 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.77 68.0 5.42e-01 94.0% 51.0%
3969115 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.76 63.0 5.73e-01 86.7% 85.7%
3959149 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.76 63.0 6.16e-01 90.4% 85.6%
4936284 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.75 62.0 5.48e-01 86.7% 85.2%
3941418 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.73 56.0 4.90e-01 80.7% 85.8%
4200953 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.73 64.0 5.17e-01 95.2% 85.2%
3943153 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.71 64.0 5.43e-01 96.4% 86.2%
3978568 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.71 61.0 5.15e-01 92.8% 79.3%
4981577 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.70 62.0 5.38e-01 95.2% 80.8%
4285602 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.69 61.0 5.20e-01 95.2% 83.1%
3942169 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.68 60.0 5.17e-01 95.2% 83.2%