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MK613344.1__QBQ72520.1__CRP2_gp44__00044

Bact-Vir

MK613344.1__QBQ72520.1__CRP2_gp44__00044

Identity

Accession:
MK613344 ↗
Kingdom:
phage

Quality

72.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 22-125
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8himB01 3.90.1110.10 Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 0.60 44.0 3.96e-01 77.9% 90.1%
7b7tA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 44.0 3.78e-01 76.9% 76.4%
3sp1A02 1.20.120.1910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cysteine-tRNA ligase, C-terminal anti-codon recognition domain 0.59 36.0 3.22e-01 75.0% 41.1%
2yyiA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 46.0 3.66e-01 85.6% 70.1%
2hpsA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.54 40.0 3.37e-01 78.8% 89.1%
1a7mA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 47.0 3.97e-01 100.0% 69.4%
1d9cA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 40.0 3.82e-01 78.8% 67.8%
2fd5A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 36.0 3.41e-01 71.2% 87.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 46.0 4.08e-01 100.0% 75.7%
2p1aB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 36.0 3.30e-01 73.1% 75.3%
2qsbA00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.51 38.0 4.10e-01 80.8% 95.3%
3g0oA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.50 35.0 3.39e-01 72.1% 87.6%
7p5hB03 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.50 39.0 4.18e-01 91.3% 100.0%
4eqyA02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.50 32.0 3.70e-01 84.6% 94.3%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3894562 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.61 42.0 4.18e-01 71.2% 98.2%
3700007 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 41.0 3.10e-01 71.2% 60.4%
4026771 109.4.1.1603 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, IBN_N, HEAT_EZ 0.54 40.0 2.29e-01 78.8% 12.8%
4961594 633.11.1.1 alpha bundles › Bromodomain-like › Nqo1C-terminal domain-like › Nqo1C-terminal domain-like › NADH_4Fe-4S 0.53 42.0 4.49e-01 87.5% 100.0%
5055634 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.53 38.0 4.20e-01 80.8% 96.2%
3599992 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 39.0 2.79e-01 76.9% 73.8%
3596599 4015.1.1.0 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins 0.53 47.0 3.63e-01 99.0% 96.6%
4967952 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.52 36.0 2.77e-01 71.2% 30.8%
4049578 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.52 39.0 4.17e-01 82.7% 94.3%
4259041 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.52 46.0 3.80e-01 100.0% 67.7%
4164964 140.1.1.14 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e 0.52 39.0 3.58e-01 79.8% 85.0%
4942190 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.52 38.0 4.11e-01 81.7% 93.2%
4029217 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.52 39.0 2.79e-01 80.8% 36.0%
5001354 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.52 39.0 4.20e-01 83.7% 95.5%
3840974 150.3.1.2 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Interferon 0.52 45.0 4.01e-01 99.0% 77.4%
5073378 109.4.1.207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 0.51 39.0 3.13e-01 80.8% 85.9%
4932900 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.51 39.0 4.10e-01 81.7% 91.4%
3671776 109.4.1.2 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.51 38.0 3.01e-01 77.9% 59.1%
4956583 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.51 38.0 3.93e-01 80.8% 87.2%
4558773 109.4.1.1259 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_PBS, HEAT_2 0.51 39.0 2.72e-01 81.7% 92.4%
3533017 150.3.1.6 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL10 0.50 45.0 3.96e-01 100.0% 80.0%
D2 medium residues 160-222
PDB
D3 medium residues 223-345
PDB
D4 medium residues 346-438
PDB
D5 medium residues 439-606
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.65 33.0 4.00e-01 80.4% 72.8%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.61 37.0 4.21e-01 85.1% 78.6%
3i9yA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 33.0 2.98e-01 79.8% 37.6%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.60 36.0 4.07e-01 85.7% 76.6%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 29.0 3.41e-01 78.0% 63.9%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.60 35.0 3.63e-01 81.5% 60.8%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 33.0 3.78e-01 76.8% 73.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 30.0 3.58e-01 78.6% 70.8%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 27.0 3.24e-01 75.6% 62.7%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.56 37.0 4.36e-01 83.9% 100.0%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.56 35.0 3.72e-01 89.3% 70.1%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.55 30.0 3.54e-01 78.0% 73.1%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 27.0 3.36e-01 89.3% 75.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 37.0 4.30e-01 82.7% 98.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 34.0 4.02e-01 92.3% 98.1%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 36.0 4.20e-01 77.4% 95.9%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.53 37.0 3.92e-01 83.9% 80.1%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 41.0 3.77e-01 80.4% 89.0%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 33.0 3.85e-01 85.1% 89.7%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 32.0 3.84e-01 83.9% 95.3%
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 25.0 2.86e-01 76.8% 56.5%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.52 33.0 3.81e-01 83.9% 89.9%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 39.0 3.73e-01 79.8% 89.1%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.50 35.0 3.77e-01 84.5% 82.4%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3894393 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.62 34.0 3.64e-01 78.0% 58.0%
3830809 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.61 33.0 3.79e-01 75.0% 70.8%
3530722 4177.1.1.150 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF4745 0.59 42.0 4.67e-01 79.8% 91.9%
3802509 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.57 31.0 3.26e-01 76.8% 56.7%
3401839 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 31.0 3.47e-01 79.2% 65.9%
3803172 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.55 39.0 4.00e-01 83.9% 75.6%
3229912 633.21.1.4 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P 0.55 32.0 3.72e-01 79.8% 80.0%
3815191 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.54 38.0 3.92e-01 83.3% 75.3%
3988033 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 34.0 3.28e-01 84.5% 55.1%
4951671 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 33.0 3.21e-01 85.1% 53.7%
4003862 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.53 41.0 3.64e-01 80.4% 70.6%
3601852 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 38.0 3.86e-01 88.7% 72.9%
4993695 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 28.0 2.71e-01 72.0% 42.1%
3826788 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.53 33.0 3.27e-01 84.5% 57.2%
3963135 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.53 34.0 3.30e-01 95.8% 55.8%
3914665 604.5.1.10 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › HRG 0.52 34.0 3.65e-01 83.9% 75.7%
3480068 174.1.1.32 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Transmemb_17 0.52 32.0 3.28e-01 87.5% 62.3%
3485540 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.51 36.0 3.56e-01 84.5% 68.6%
3940449 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.51 33.0 3.46e-01 85.1% 68.8%
3436634 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.50 36.0 3.75e-01 83.3% 79.4%
D6 medium residues 607-673
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 52.0 4.40e-01 86.6% 66.4%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 40.0 3.12e-01 70.1% 57.2%
1xfiA02 1.20.1700.10 Mainly Alpha › Up-down Bundle › AF1104-like › AF1104-like 0.58 39.0 3.60e-01 70.1% 75.6%
2yfkA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.56 46.0 3.36e-01 94.0% 69.9%
2lwdA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.55 42.0 3.70e-01 80.6% 69.8%
6k93A00 3.90.176.10 Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 0.54 44.0 3.16e-01 98.5% 42.3%
1cmjA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 44.0 2.72e-01 92.5% 20.1%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 40.0 3.27e-01 86.6% 85.0%
2z3xA00 6.10.10.80 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › Small, acid-soluble spore protein, alpha/beta type-like 0.51 33.0 3.50e-01 85.1% 80.4%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3933449 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.60 40.0 3.67e-01 70.1% 97.8%
4234479 3694.1.1.2 alpha bundles › Tail specific protease helical domain › Tail specific protease helical domain › Tail specific protease helical domain › Tricorn_C1 0.54 36.0 3.37e-01 70.1% 60.0%
2557383 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.52 36.0 3.10e-01 76.1% 65.9%
D7 medium residues 674-781
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zzwA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 36.0 3.30e-01 79.6% 46.3%
2ox6D00 1.10.3100.10 Mainly Alpha › Orthogonal Bundle › Putative cytoplasmic protein › Putative cytoplasmic protein 0.56 50.0 4.40e-01 98.1% 79.5%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 4.18e-01 79.6% 89.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 34.0 3.73e-01 77.8% 72.8%
4x28C01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 42.0 4.07e-01 81.5% 92.4%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.52 27.0 2.93e-01 96.3% 56.8%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.51 36.0 3.96e-01 74.1% 98.8%
6opmD01 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.50 41.0 3.20e-01 88.9% 90.3%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 37.0 3.75e-01 75.9% 61.8%
5039964 109.2.1.2 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_15 0.55 48.0 3.33e-01 99.1% 82.3%
3757437 109.4.1.1194 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TMC 0.53 43.0 3.02e-01 88.0% 56.7%
3665947 109.4.1.189 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.53 33.0 3.09e-01 70.4% 48.1%
4229570 3018.1.1.0 a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like 0.53 32.0 3.85e-01 72.2% 100.0%
3393874 109.4.1.1362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_C 0.52 44.0 2.81e-01 92.6% 29.3%
4240325 3018.1.1.1 a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › TilS 0.52 33.0 3.51e-01 72.2% 75.6%
3924798 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 43.0 2.82e-01 90.7% 33.8%
138422 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.51 40.0 3.88e-01 88.0% 80.2%
4362276 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 36.0 3.42e-01 74.1% 81.5%
3904284 601.1.3.15 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › MNR 0.50 39.0 3.40e-01 85.2% 78.9%
D8 medium residues 1061-1120
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ynqB00 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.80 54.0 3.91e-01 83.3% 27.8%
2hydA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.79 56.0 3.45e-01 88.3% 13.9%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.77 56.0 3.80e-01 76.7% 70.6%
2efeA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.76 51.0 4.59e-01 70.0% 85.2%
2kiwA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.74 54.0 4.74e-01 76.7% 93.0%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.72 50.0 4.29e-01 71.7% 54.3%
2gsvA00 6.10.140.40 Special › Helix non-globular › Helix Hairpins › 0.72 56.0 5.39e-01 81.7% 82.1%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.72 55.0 4.33e-01 93.3% 41.0%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 48.0 4.94e-01 83.3% 75.4%
4m0mA04 1.20.1270.440 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 59.0 4.70e-01 100.0% 47.9%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.66 47.0 4.59e-01 100.0% 69.7%
4efcA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.65 48.0 4.82e-01 78.3% 96.7%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.64 42.0 3.83e-01 76.7% 50.6%
8gy0A01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 48.0 3.15e-01 83.3% 92.5%
1w36C06 1.10.10.990 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.64 42.0 4.06e-01 70.0% 73.6%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 46.0 3.82e-01 88.3% 43.5%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.63 50.0 3.43e-01 86.7% 26.2%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 43.0 3.87e-01 81.7% 51.2%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 46.0 3.41e-01 83.3% 31.8%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 41.0 3.52e-01 81.7% 43.1%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.60 47.0 4.68e-01 88.3% 81.0%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 47.0 3.69e-01 90.0% 64.2%
2dpyA00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 50.0 3.07e-01 100.0% 40.0%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.58 50.0 4.45e-01 96.7% 73.6%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.58 42.0 3.80e-01 81.7% 55.3%
1kv9A02 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.57 49.0 4.15e-01 96.7% 92.2%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 38.0 2.91e-01 85.0% 27.5%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.56 41.0 3.96e-01 88.3% 68.1%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.56 42.0 3.90e-01 83.3% 96.1%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.55 44.0 3.46e-01 88.3% 41.6%
6b8hO01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.54 42.0 3.69e-01 100.0% 54.5%
2wa5A01 1.10.418.10 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain 0.54 43.0 3.74e-01 95.0% 100.0%
4lrjA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.54 47.0 4.14e-01 98.3% 80.5%
2gwgA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.53 44.0 2.83e-01 95.0% 82.6%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4202292 570.1.1.1 alpha arrays › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › Pre-protein crosslinking domain of SecA › SecA_PP_bind 0.92 58.0 3.79e-01 83.3% 18.1%
3267759 4.1.1.140 beta barrels › SH3 › SH3 › SH3 › Pif1_2B_dom 0.84 58.0 4.10e-01 76.7% 26.9%
5004436 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 54.0 3.82e-01 83.3% 24.3%
4112673 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.80 58.0 4.02e-01 95.0% 25.3%
223819 109.28.1.1 alpha superhelices › Repetitive alpha hairpins › EssB extracellular domain › EssB extracellular domain › YukC 0.79 53.0 3.93e-01 83.3% 28.2%
3720226 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.79 57.0 4.27e-01 95.0% 33.3%
3717826 547.1.1.0 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain 0.79 57.0 4.63e-01 95.0% 42.9%
4033037 632.19.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 0.79 55.0 5.26e-01 95.0% 62.9%
3214189 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 55.0 4.47e-01 90.0% 41.9%
3389059 4082.1.1.1 alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange 0.78 55.0 5.71e-01 90.0% 80.0%
3394861 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.77 58.0 3.92e-01 96.7% 24.1%
4460746 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.77 57.0 3.94e-01 95.0% 25.6%
3457578 3846.1.1.0 alpha bundles › IcmR › IcmR › IcmR 0.77 50.0 5.66e-01 81.7% 88.9%
3938243 3065.1.1.1 alpha bundles › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › Fatty acid- and retinoid-binding proteins › ANIS5_cation-bd 0.77 54.0 3.50e-01 90.0% 18.0%
3925867 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.77 55.0 3.29e-01 95.0% 11.7%
3212006 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.77 57.0 4.35e-01 96.7% 36.2%
3223457 101.1.2.661 alpha arrays › HTH › HTH › winged helix domain › HTH_9, POLR3C_WHD 0.76 56.0 3.55e-01 98.3% 16.4%
3623842 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.75 57.0 4.39e-01 98.3% 38.4%
3582573 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.75 55.0 4.39e-01 96.7% 41.8%
3630104 192.24.1.6 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.74 55.0 3.27e-01 96.7% 12.1%
5001312 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.74 53.0 4.81e-01 75.0% 93.8%
3507828 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.74 57.0 3.49e-01 95.0% 15.2%
4034213 632.2.1.5 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 0.74 56.0 5.06e-01 95.0% 60.0%
4562953 2004.1.1.43 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 0.74 52.0 3.27e-01 90.0% 15.4%
3992791 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.74 50.0 4.23e-01 83.3% 44.2%
4034449 109.28.1.1 alpha superhelices › Repetitive alpha hairpins › EssB extracellular domain › EssB extracellular domain › YukC 0.73 49.0 3.65e-01 83.3% 28.0%
4235299 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.73 56.0 3.86e-01 81.7% 84.8%
4169956 604.12.1.26 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › HemX 0.73 46.0 4.28e-01 83.3% 52.0%
4229998 109.28.1.1 alpha superhelices › Repetitive alpha hairpins › EssB extracellular domain › EssB extracellular domain › YukC 0.72 46.0 3.55e-01 80.0% 29.6%
5018387 604.18.1.0 alpha bundles › Spectrin repeat-like › Triple-helical domain in regulatory ATPase variant A (RavA) › Triple-helical domain in regulatory ATPase variant A (RavA) 0.71 50.0 4.14e-01 86.7% 41.9%
4026047 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 53.0 4.74e-01 96.7% 56.5%
3930816 101.1.2.236 alpha arrays › HTH › HTH › winged helix domain › POLR3C_WHD 0.69 54.0 3.44e-01 96.7% 17.8%
5022284 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.69 50.0 4.70e-01 100.0% 62.7%
3399070 4082.1.1.1 alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain › Hairy_orange 0.67 47.0 4.90e-01 86.7% 81.8%
4003615 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.66 49.0 3.30e-01 95.0% 21.3%
3442159 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 59.0 5.00e-01 98.3% 72.6%
5026703 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.66 55.0 3.41e-01 95.0% 23.0%
4083184 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.65 50.0 4.24e-01 83.3% 97.0%
3610092 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.65 58.0 4.61e-01 95.0% 59.1%
3533060 110.1.1.0 alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.64 43.0 3.55e-01 75.0% 36.5%
3719935 164.1.1.0 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II 0.63 58.0 4.78e-01 98.3% 71.0%
3913300 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.62 44.0 3.39e-01 88.3% 30.7%
4960839 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 55.0 4.66e-01 100.0% 86.0%
3839497 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.62 45.0 4.00e-01 76.7% 92.9%
1391387 4953.1.1.1 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ASL_C 0.62 52.0 4.79e-01 95.0% 87.2%
3921951 632.8.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 0.61 53.0 4.71e-01 96.7% 100.0%
3500868 2006.1.1.9 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › UMPH-1 0.60 50.0 3.19e-01 98.3% 18.1%
1007309 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.59 53.0 3.84e-01 100.0% 51.8%
3650037 604.1.1.127 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 0.57 46.0 3.63e-01 88.3% 44.8%
4344838 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.55 42.0 3.81e-01 81.7% 91.3%
3176953 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.53 41.0 3.90e-01 83.3% 90.0%
3379763 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.50 39.0 3.57e-01 83.3% 80.0%
3916833 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.50 39.0 3.56e-01 83.3% 78.8%