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MK733259.1__QCW23377.1__X__00033

Bact-Vir

MK733259.1__QCW23377.1__X__00033

Identity

Accession:
MK733259 ↗
Kingdom:
phage

Quality

87.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 90-136
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.90 76.0 6.19e-01 95.7% 51.8%
4hkaA02 1.10.287.3810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.88 72.0 7.00e-01 91.5% 82.4%
1ezjA01 1.10.287.320 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Viral phosphoprotein oligmorisation site domain 0.88 61.0 5.48e-01 76.6% 54.8%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.86 68.0 5.67e-01 89.4% 50.6%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.85 75.0 5.04e-01 100.0% 27.2%
2l1lB00 1.20.1440.250 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.85 71.0 5.08e-01 95.7% 33.9%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 68.0 5.72e-01 95.7% 53.9%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.85 73.0 5.90e-01 95.7% 54.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 74.0 4.67e-01 100.0% 19.9%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.84 69.0 6.92e-01 93.6% 89.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 74.0 6.39e-01 100.0% 64.4%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 73.0 5.68e-01 100.0% 47.0%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.83 73.0 5.08e-01 100.0% 32.0%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.83 73.0 5.22e-01 100.0% 34.8%
2a26B01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.82 65.0 6.70e-01 93.6% 93.2%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.82 74.0 5.37e-01 100.0% 39.3%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.81 71.0 4.93e-01 100.0% 30.7%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 71.0 5.81e-01 100.0% 54.0%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.81 72.0 4.40e-01 100.0% 22.2%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.81 70.0 5.29e-01 100.0% 41.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.80 71.0 5.72e-01 100.0% 51.6%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.80 69.0 6.42e-01 100.0% 78.0%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 67.0 5.11e-01 100.0% 40.2%
1vf6C00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.79 69.0 6.73e-01 97.9% 94.1%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.79 67.0 5.69e-01 100.0% 87.8%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 68.0 4.29e-01 100.0% 19.8%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 62.0 5.30e-01 93.6% 53.8%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.78 64.0 6.37e-01 100.0% 89.6%
4hb1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.78 64.0 6.61e-01 93.6% 97.7%
6dcjA02 1.25.40.650 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.78 60.0 4.64e-01 87.2% 38.5%
2jdiH02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.78 62.0 6.44e-01 93.6% 100.0%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 65.0 5.84e-01 100.0% 67.6%
3mzlB02 6.10.140.1600 Special › Helix non-globular › Helix Hairpins › 0.78 54.0 5.15e-01 76.6% 62.5%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 64.0 4.30e-01 100.0% 24.1%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.77 63.0 4.51e-01 100.0% 30.3%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 66.0 5.71e-01 100.0% 64.0%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 67.0 4.80e-01 100.0% 35.0%
4l7mA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.77 58.0 3.66e-01 87.2% 15.3%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 67.0 4.71e-01 100.0% 32.6%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 63.0 5.44e-01 100.0% 59.0%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.76 66.0 5.66e-01 100.0% 61.8%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 62.0 5.52e-01 97.9% 80.6%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.75 64.0 4.61e-01 100.0% 35.5%
4gczA03 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.73 59.0 5.46e-01 100.0% 70.8%
1cpyA02 1.10.287.410 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 57.0 5.00e-01 95.7% 58.3%
7vkcA01 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.70 52.0 3.61e-01 95.7% 23.6%
2e5yA02 1.20.5.440 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain 0.69 57.0 5.78e-01 97.9% 100.0%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.69 53.0 4.72e-01 95.7% 57.5%
2q0oA01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.67 49.0 3.35e-01 78.7% 82.1%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 53.0 4.80e-01 100.0% 68.0%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.66 56.0 4.34e-01 100.0% 44.0%
3e98B00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.62 51.0 3.51e-01 95.7% 68.4%
2py6A01 1.20.1270.160 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 42.0 3.83e-01 100.0% 63.0%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3994877 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.93 69.0 4.94e-01 80.9% 30.8%
3902068 109.4.1.1369 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MA3, MIF4G 0.93 83.0 4.56e-01 100.0% 8.1%
4017128 5055.1.1.6 extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel › CENPU 0.91 84.0 5.55e-01 100.0% 28.5%
5077689 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.91 80.0 5.82e-01 100.0% 38.3%
4127368 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.90 79.0 7.71e-01 97.9% 88.0%
3931081 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.90 65.0 4.53e-01 76.6% 27.4%
3548030 548.1.1.1 alpha duplicates or obligate multimers › GRIP domain › GRIP domain › GRIP domain › GRIP 0.89 63.0 6.16e-01 78.7% 70.0%
5025209 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 79.0 4.90e-01 100.0% 19.6%
3974197 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.88 77.0 6.40e-01 100.0% 57.5%
3586032 605.1.1.237 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Patched 0.87 77.0 5.91e-01 100.0% 45.7%
3704286 604.12.1.8 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.87 78.0 6.00e-01 100.0% 47.0%
4981193 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.87 78.0 4.79e-01 100.0% 18.4%
3978513 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.86 74.0 6.21e-01 100.0% 57.5%
3267005 650.1.1.0 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.86 76.0 5.82e-01 100.0% 47.6%
4976497 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.86 76.0 5.58e-01 100.0% 39.2%
4573348 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.86 77.0 6.86e-01 100.0% 83.1%
4190254 159.1.1.4 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › PRA-PH 0.86 73.0 5.45e-01 95.7% 40.0%
3708624 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 75.0 4.11e-01 97.9% 8.0%
3699985 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 74.0 4.37e-01 97.9% 13.5%
3595965 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 75.0 4.44e-01 97.9% 16.7%
2814929 150.1.1.14 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like 0.85 76.0 6.67e-01 100.0% 69.1%
3987389 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.85 74.0 4.16e-01 100.0% 9.1%
3253223 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.85 77.0 5.65e-01 100.0% 40.9%
3655741 7542.1.1.0 a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain 0.85 65.0 4.69e-01 89.4% 31.2%
1822527 101.1.2.135 alpha arrays › HTH › HTH › winged helix domain › MarR_2 0.85 74.0 5.13e-01 97.9% 30.9%
3717958 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.84 75.0 4.09e-01 100.0% 6.8%
5000553 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.84 75.0 6.55e-01 100.0% 71.4%
3699638 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.84 75.0 4.12e-01 100.0% 7.1%
3677540 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.84 74.0 4.39e-01 100.0% 14.0%
4590991 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.84 71.0 7.10e-01 97.9% 91.7%
3298870 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.84 75.0 5.70e-01 100.0% 44.8%
4397104 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.83 73.0 6.25e-01 100.0% 62.7%
2323867 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 74.0 6.77e-01 100.0% 88.5%
4351951 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.83 69.0 7.07e-01 95.7% 95.6%
5073085 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 73.0 4.95e-01 100.0% 28.7%
3215342 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 73.0 5.75e-01 100.0% 64.2%
4965632 192.7.1.85 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › DUF4349 0.82 73.0 6.58e-01 100.0% 76.9%
3089539 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.82 72.0 4.38e-01 100.0% 18.6%
3581869 192.14.1.0 alpha bundles › Long alpha-hairpin › Siah interacting protein N terminal domain-like › Siah interacting protein N terminal domain-like 0.82 72.0 7.11e-01 100.0% 94.0%
4465242 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.81 71.0 7.29e-01 100.0% 100.0%
4937862 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.81 71.0 5.41e-01 100.0% 42.7%
4248599 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.81 71.0 7.14e-01 100.0% 95.8%
3976663 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.81 70.0 6.36e-01 100.0% 72.3%
3289740 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.81 71.0 6.59e-01 100.0% 80.0%
3385229 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.81 69.0 4.05e-01 100.0% 12.6%
5048061 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.81 70.0 6.74e-01 100.0% 85.5%
4048210 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.81 68.0 6.94e-01 95.7% 97.8%
3485269 192.6.1.3 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATPD_C_metazoa 0.81 69.0 7.02e-01 97.9% 100.0%
3716015 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.80 70.0 6.46e-01 97.9% 90.0%
57654 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.80 70.0 6.75e-01 100.0% 87.0%
3961229 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.80 71.0 4.65e-01 100.0% 48.4%
3741785 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.80 69.0 5.40e-01 100.0% 46.0%
3554931 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.79 69.0 6.67e-01 100.0% 88.9%
4429835 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.78 68.0 5.34e-01 100.0% 48.0%
3288075 2004.1.1.600 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn, AAA_21 0.78 69.0 3.86e-01 100.0% 17.6%
3776400 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.78 67.0 5.70e-01 100.0% 58.7%
4964878 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 67.0 5.95e-01 100.0% 67.1%
4530477 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.78 65.0 6.68e-01 97.9% 100.0%
3958 150.1.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.76 67.0 4.67e-01 100.0% 31.5%
4268056 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.75 64.0 6.18e-01 97.9% 83.6%
4613072 101.1.2.721 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27113 0.75 64.0 4.46e-01 100.0% 28.5%
4803705 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.74 61.0 5.63e-01 100.0% 71.2%
4089954 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.74 59.0 6.08e-01 95.7% 95.6%
4174467 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.73 63.0 5.18e-01 100.0% 53.3%
4062575 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.72 61.0 6.03e-01 100.0% 92.0%
D2 medium residues 4-40
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xzzA00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.82 65.0 3.98e-01 100.0% 15.3%
4hhxA00 1.20.81.30 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › Type II secretion system (T2SS), domain F 0.79 61.0 4.51e-01 89.2% 32.7%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.77 66.0 4.59e-01 100.0% 31.7%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.77 62.0 4.49e-01 100.0% 42.7%
1lfkA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.76 62.0 3.59e-01 100.0% 9.6%
3m1cB01 3.30.390.170 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.76 54.0 3.90e-01 94.6% 26.6%
3pdiA02 3.40.50.12380 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase MoFe cofactor biosynthesis protein NifE, C-terminal 0.76 63.0 3.74e-01 100.0% 13.2%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.76 59.0 4.20e-01 100.0% 28.7%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 60.0 4.03e-01 100.0% 24.2%
2l89A00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.73 57.0 4.19e-01 97.3% 31.5%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 55.0 4.39e-01 100.0% 39.8%
2ehgA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.71 58.0 3.79e-01 86.5% 22.1%
3qxyA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.70 57.0 3.76e-01 100.0% 21.6%
3nuwA02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.69 56.0 3.52e-01 91.9% 38.0%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 57.0 4.96e-01 100.0% 66.1%
4p32B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 51.0 3.13e-01 91.9% 13.0%
2ds2D01 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.68 49.0 4.31e-01 83.8% 50.9%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 53.0 3.78e-01 100.0% 35.5%
2ga1A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 50.0 4.10e-01 89.2% 71.8%
2z86D01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.63 49.0 2.92e-01 97.3% 11.4%
7ce1A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.63 47.0 4.35e-01 83.8% 80.8%
2iexA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.61 49.0 4.53e-01 94.6% 74.5%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3501998 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.81 71.0 5.38e-01 100.0% 45.9%
3738995 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.80 62.0 5.24e-01 89.2% 52.3%
3890229 603.1.1.64 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › CUPID 0.79 67.0 4.95e-01 100.0% 36.8%
3615712 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.79 64.0 4.93e-01 100.0% 41.1%
4375086 605.1.1.108 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE 0.76 64.0 5.60e-01 100.0% 63.6%
1124217 3791.1.1.1 alpha arrays › EDS1-PAD4 (EP) domain › EDS1-PAD4 (EP) domain › EDS1-PAD4 (EP) domain › EDS1_EP 0.76 62.0 3.82e-01 100.0% 14.9%
4436335 3390.1.1.0 extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT 0.75 62.0 5.86e-01 100.0% 77.8%
4283243 2004.1.1.149 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SecA_DEAD 0.74 62.0 3.66e-01 100.0% 10.9%
3735991 109.4.1.526 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Atx10homo_assoc 0.74 60.0 3.30e-01 100.0% 5.7%
3357448 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.73 62.0 5.72e-01 100.0% 74.0%
3514231 376.1.1.20 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX 0.73 60.0 4.07e-01 100.0% 24.7%
3804522 1147.1.1.1 alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL 0.73 59.0 4.24e-01 100.0% 30.0%
3173131 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.72 57.0 4.00e-01 97.3% 29.6%
3224052 4041.1.1.1 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.69 59.0 3.74e-01 100.0% 91.1%
3587609 101.1.4.2 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › LacI 0.62 47.0 4.32e-01 83.8% 84.0%
D3 medium residues 45-78
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2drpA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.83 60.0 6.38e-01 82.4% 89.7%
2rsiA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.77 54.0 5.65e-01 82.4% 89.7%
1a1iA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.77 55.0 5.71e-01 82.4% 90.0%
5k5iA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.76 52.0 4.64e-01 79.4% 48.1%
3laaA00 2.150.10.10 Mainly Beta › 2 Solenoid › Alkaline Protease, subunit P, domain 1 › Serralysin-like metalloprotease, C-terminal 0.72 52.0 3.41e-01 85.3% 17.8%
2dlkA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.71 50.0 5.09e-01 79.4% 100.0%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.70 54.0 3.65e-01 100.0% 47.9%
2kyzA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 54.0 4.56e-01 100.0% 98.5%
3w7tA04 3.30.1390.40 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30p/L7e 0.65 50.0 5.11e-01 94.1% 100.0%
3nuhB02 3.30.300.370 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.64 50.0 3.63e-01 100.0% 93.4%
2a25A01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.63 45.0 4.57e-01 82.4% 96.4%
5zjgA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.62 45.0 3.35e-01 91.2% 73.2%
3g8qA02 3.30.70.1940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 42.0 3.62e-01 97.1% 92.5%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.60 49.0 3.68e-01 100.0% 89.4%
1ygyA04 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 42.0 3.67e-01 100.0% 94.7%
2bkfA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.59 46.0 3.70e-01 100.0% 89.2%
2xmjA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 43.0 3.79e-01 91.2% 98.4%
1y9zB01 3.40.50.200 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain 0.57 40.0 2.49e-01 94.1% 35.1%
3fdjA02 2.20.28.50 Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › DegV, N-terminal domain, peripheral subdomain 0.57 48.0 4.72e-01 100.0% 100.0%
7oslA02 3.40.50.12790 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › FHIPEP family, domain 4 0.56 40.0 3.03e-01 79.4% 34.0%
1ujrA01 3.30.720.50 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.55 43.0 3.46e-01 100.0% 78.3%
1h3dA03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 41.0 3.59e-01 100.0% 88.1%
3r4cA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.54 38.0 2.97e-01 82.4% 91.1%
3tj8A02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.53 41.0 3.53e-01 100.0% 79.7%
6tg9C01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 35.0 3.05e-01 76.5% 33.8%
2w42B01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 40.0 2.81e-01 97.1% 99.4%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3388950 386.1.1.1 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.83 59.0 5.61e-01 82.4% 65.0%
3483618 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.81 63.0 5.76e-01 100.0% 64.0%
4992851 5103.1.1.2 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › DUF1015 0.79 64.0 4.37e-01 100.0% 99.2%
3401438 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.79 60.0 5.32e-01 85.3% 76.0%
3941506 2002.1.1.16 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase 0.78 63.0 3.63e-01 100.0% 11.0%
4942530 5103.1.1.0 a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 0.77 61.0 4.23e-01 97.1% 98.4%
3243928 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.72 56.0 5.59e-01 100.0% 91.4%
1734768 4187.1.1.1 a+b two layers › NosL/MerB-like › NosL/MerB-like › NosL/MerB-like › MerB 0.71 54.0 4.86e-01 100.0% 60.3%
3546841 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.71 52.0 5.03e-01 79.4% 67.5%
4139949 379.1.1.0 few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors 0.70 57.0 5.53e-01 100.0% 85.0%
4927165 4187.1.1.1 a+b two layers › NosL/MerB-like › NosL/MerB-like › NosL/MerB-like › MerB 0.69 53.0 4.84e-01 100.0% 63.6%
3397134 379.1.1.0 few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors 0.69 56.0 5.13e-01 100.0% 70.0%
3400250 379.1.1.3 few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors › Kazal_2 0.66 55.0 5.01e-01 100.0% 68.0%
3789608 2006.1.3.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.66 53.0 3.20e-01 100.0% 13.5%
5025013 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.65 53.0 4.71e-01 100.0% 96.4%
4005326 109.2.1.42 alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › MGH1-like_GH 0.64 50.0 2.81e-01 100.0% 6.5%
3475434 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.64 47.0 4.31e-01 85.3% 60.0%
4196780 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.62 48.0 4.86e-01 97.1% 100.0%
4981662 821.1.1.14 a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › DUF2797 0.61 46.0 3.77e-01 100.0% 41.2%
3935777 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 43.0 3.69e-01 100.0% 42.5%
4646021 308.2.1.0 a+b two layers › ClpS-like › Penicillin binding protein ClpS-like domain › Penicillin binding protein ClpS-like domain 0.60 43.0 3.77e-01 97.1% 98.6%
3303628 822.1.1.3 a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF_ATXR3 0.60 43.0 4.13e-01 100.0% 74.0%
1736418 304.3.1.1 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.59 42.0 3.76e-01 94.1% 100.0%
3281602 379.1.1.0 few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors 0.58 42.0 4.11e-01 100.0% 91.7%
432311 304.22.1.1 a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain › UreE_C 0.57 40.0 3.48e-01 100.0% 73.8%
3800155 101.1.15.1 alpha arrays › HTH › HTH › HAT1, C-terminal domain › MOZ_SAS 0.57 41.0 3.11e-01 79.4% 54.1%
4958791 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.56 39.0 3.68e-01 100.0% 96.7%
3962632 7504.1.1.3 a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like › Maf 0.56 44.0 2.97e-01 88.2% 46.4%
4958363 876.1.1.1 a+b complex topology › ParB/Sulfiredoxin › ParB/Sulfiredoxin › ParB/Sulfiredoxin › ParBc 0.55 38.0 3.03e-01 73.5% 45.9%
4928538 2003.1.5.42 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_21 0.55 45.0 2.87e-01 100.0% 23.4%