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MK814756.1__QCG77502.1__SEA_DIZZYRUDY_5__00005

Bact-Vir

MK814756.1__QCG77502.1__SEA_DIZZYRUDY_5__00005

Identity

Accession:
MK814756 ↗
Kingdom:
phage

Quality

80.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-115
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23778.2 best Phage_holin_2 39.3 9.10e-10 87.8% 91.3%
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 56.0 5.78e-01 99.1% 92.5%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 57.0 5.69e-01 94.8% 89.0%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 60.0 4.70e-01 98.3% 89.6%
7akwA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 57.0 4.60e-01 95.7% 99.5%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 57.0 5.21e-01 98.3% 77.1%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 55.0 4.56e-01 94.8% 87.1%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.64 50.0 4.30e-01 84.3% 58.6%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 55.0 4.60e-01 99.1% 96.2%
2qkwA00 1.20.1270.140 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto 0.62 51.0 5.35e-01 98.3% 100.0%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.62 53.0 4.39e-01 92.2% 85.0%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 45.0 3.98e-01 75.7% 77.2%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 46.0 4.20e-01 97.4% 60.0%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.59 49.0 4.59e-01 97.4% 71.5%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 43.0 4.32e-01 96.5% 74.2%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.59 40.0 4.19e-01 87.0% 75.9%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 46.0 3.54e-01 84.3% 74.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.58 46.0 4.59e-01 94.8% 81.5%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 44.0 3.61e-01 79.1% 70.1%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.58 50.0 4.31e-01 98.3% 58.2%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.58 41.0 4.15e-01 92.2% 73.5%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.58 48.0 4.67e-01 88.7% 91.4%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 48.0 4.45e-01 94.8% 98.7%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.56 44.0 3.71e-01 84.3% 75.5%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 49.0 4.37e-01 99.1% 89.5%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 48.0 4.41e-01 96.5% 90.9%
4i8qA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.56 45.0 3.40e-01 88.7% 47.0%
2f2gA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.56 50.0 4.09e-01 100.0% 78.1%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 3.65e-01 73.0% 66.0%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.55 45.0 3.74e-01 87.0% 76.7%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 44.0 4.34e-01 86.1% 97.6%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 48.0 4.32e-01 100.0% 86.4%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 47.0 4.21e-01 99.1% 86.9%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 47.0 4.21e-01 99.1% 88.4%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 46.0 4.11e-01 94.8% 85.0%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.54 43.0 4.16e-01 89.6% 89.1%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 47.0 4.26e-01 100.0% 94.3%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 45.0 4.05e-01 95.7% 89.0%
1yuzB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 44.0 4.22e-01 93.9% 100.0%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 45.0 4.29e-01 96.5% 100.0%
7w5lA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.53 43.0 3.37e-01 88.7% 54.7%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 46.0 3.87e-01 100.0% 75.5%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 44.0 4.01e-01 98.3% 98.7%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 47.0 4.55e-01 100.0% 88.5%
3wmeA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.50 42.0 3.10e-01 92.2% 91.5%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 43.0 4.47e-01 98.3% 99.1%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5039785 632.22.1.200 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 0.80 62.0 6.85e-01 89.6% 98.9%
4993195 632.6.1.15 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › PF26119 0.80 63.0 6.92e-01 92.2% 100.0%
5010044 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.77 61.0 6.66e-01 91.3% 100.0%
4465076 3755.4.1.24 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF2463 0.72 54.0 5.10e-01 88.7% 65.0%
3644115 603.1.1.177 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF641 0.71 57.0 5.51e-01 95.7% 76.9%
5043412 1025.1.1.0 alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.70 62.0 6.24e-01 97.4% 96.5%
3414701 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 58.0 4.42e-01 90.4% 96.2%
3933930 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.68 60.0 4.46e-01 96.5% 94.6%
5047544 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 59.0 5.45e-01 98.3% 76.6%
3593287 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 59.0 5.71e-01 98.3% 90.8%
5012747 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.65 55.0 4.67e-01 94.8% 99.5%
3739286 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.65 56.0 4.51e-01 95.7% 84.8%
4646512 633.6.1.3 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › HpaB 0.65 58.0 4.72e-01 100.0% 70.5%
3243431 904.1.1.0 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain 0.64 49.0 4.44e-01 92.2% 58.7%
3182496 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.64 44.0 3.05e-01 70.4% 92.0%
3189048 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.64 51.0 4.13e-01 86.1% 53.2%
3577239 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.63 54.0 4.29e-01 94.8% 75.4%
3655628 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.63 48.0 3.76e-01 79.1% 83.0%
4947851 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.63 56.0 5.12e-01 98.3% 76.7%
3935599 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 44.0 3.67e-01 72.2% 95.0%
3385272 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.62 44.0 2.58e-01 72.2% 18.3%
3268700 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.61 53.0 4.52e-01 97.4% 89.7%
3536875 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.61 51.0 3.84e-01 91.3% 77.9%
4996728 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 48.0 4.84e-01 84.3% 83.5%
3789186 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.60 52.0 3.92e-01 94.8% 83.8%
3606295 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.60 54.0 4.61e-01 100.0% 70.5%
3168929 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.60 43.0 3.71e-01 99.1% 48.6%
3883526 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.60 53.0 3.90e-01 97.4% 82.9%
5029347 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.60 44.0 2.88e-01 77.4% 19.6%
3782889 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.59 48.0 3.94e-01 88.7% 89.8%
3473217 633.23.1.4 alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 0.58 53.0 4.32e-01 98.3% 79.5%
3170937 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 50.0 3.84e-01 94.8% 87.3%
3927709 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 42.0 3.96e-01 98.3% 60.0%
3410814 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 46.0 4.48e-01 94.8% 77.6%
3304304 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 38.0 3.94e-01 71.3% 72.4%
4846601 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.57 50.0 4.89e-01 98.3% 86.1%
3389690 174.1.1.29 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 0.57 44.0 4.18e-01 80.9% 85.9%
3613274 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.56 49.0 4.06e-01 99.1% 60.0%
3285567 5069.1.1.17 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF6529 0.56 46.0 3.99e-01 100.0% 58.0%
3991109 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.56 46.0 4.34e-01 89.6% 81.4%
3952542 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 49.0 4.00e-01 97.4% 80.0%
3800525 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 38.0 3.52e-01 71.3% 71.6%
3096672 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.55 47.0 4.29e-01 96.5% 86.4%
3387443 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.54 45.0 4.55e-01 89.6% 90.4%
3822775 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.54 40.0 3.69e-01 80.9% 75.5%
4094257 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.54 43.0 4.18e-01 97.4% 76.2%
3832912 6155.1.1.6 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.54 48.0 3.73e-01 99.1% 99.2%
3419627 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 40.0 3.73e-01 81.7% 80.7%
3987319 604.10.1.1 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA 0.53 39.0 4.00e-01 86.1% 82.6%
4009779 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.52 43.0 4.09e-01 89.6% 88.9%
3605545 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.51 45.0 3.62e-01 99.1% 75.4%
3997389 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.51 45.0 4.12e-01 96.5% 76.1%
5031071 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.51 39.0 3.58e-01 85.2% 61.3%
162404 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.51 47.0 4.55e-01 100.0% 88.5%