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MK937595.1__QDH92141.1__SEA_DUBU_36__00036

Bact-Vir

MK937595.1__QDH92141.1__SEA_DUBU_36__00036

Identity

Accession:
MK937595 ↗
Kingdom:
phage

Quality

53.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 60-159
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04542.21 best Sigma70_r2 25.1 1.70e-05 69.0% 67.6%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.79 59.0 6.53e-01 92.0% 98.8%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.77 61.0 6.50e-01 93.0% 97.6%
6ldiF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 55.0 5.62e-01 92.0% 81.2%
4hl4A01 1.10.8.1310 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.73 51.0 4.50e-01 88.0% 50.0%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.70 52.0 5.50e-01 87.0% 88.6%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 55.0 4.56e-01 89.0% 57.3%
2fm8C01 1.10.4150.10 Mainly Alpha › Orthogonal Bundle › SipA N-terminal domain-like › SipA N-terminal domain-like 0.66 54.0 4.34e-01 96.0% 44.9%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.65 47.0 5.35e-01 80.0% 100.0%
2eb1C00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.63 56.0 4.71e-01 99.0% 85.8%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 55.0 4.53e-01 100.0% 53.2%
6fakA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.61 43.0 4.70e-01 92.0% 90.1%
2qgsB01 1.10.472.50 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like 0.61 37.0 3.89e-01 73.0% 67.0%
4k5yA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 50.0 3.76e-01 89.0% 39.9%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 44.0 4.39e-01 76.0% 84.5%
2lyiA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.59 46.0 4.11e-01 85.0% 83.1%
4f0uA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.59 48.0 4.17e-01 90.0% 81.2%
2xdoD00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 52.0 3.56e-01 100.0% 98.4%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.57 43.0 3.73e-01 79.0% 87.6%
1b8dA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.57 46.0 4.00e-01 90.0% 79.9%
1kxpD04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.57 39.0 4.28e-01 83.0% 92.2%
1to9A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.56 47.0 3.64e-01 92.0% 71.6%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.56 43.0 3.83e-01 82.0% 72.9%
4k22B01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 49.0 3.78e-01 100.0% 95.9%
4an8A02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.56 49.0 4.65e-01 100.0% 83.6%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.55 42.0 4.56e-01 98.0% 100.0%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.54 46.0 3.56e-01 94.0% 72.3%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.53 46.0 4.32e-01 94.0% 79.8%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 47.0 4.10e-01 100.0% 65.4%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 44.0 3.90e-01 96.0% 64.4%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 43.0 3.48e-01 98.0% 47.4%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.51 35.0 3.09e-01 100.0% 47.3%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.50 41.0 3.44e-01 88.0% 80.8%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.50 35.0 3.42e-01 72.0% 70.3%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5019397 5067.1.1.12 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › UPF0014 0.77 60.0 4.57e-01 83.0% 38.2%
61904 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.76 61.0 6.49e-01 99.0% 98.8%
4147641 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.74 63.0 6.14e-01 100.0% 84.5%
4420734 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.71 55.0 3.85e-01 81.0% 28.2%
5082960 159.1.2.35 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › HAAS 0.71 51.0 5.75e-01 80.0% 100.0%
4359328 142.1.1.44 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › GerPC 0.70 63.0 6.35e-01 99.0% 100.0%
3226184 101.1.10.6 alpha arrays › HTH › HTH › Cyclin-like › RB_A 0.68 56.0 4.33e-01 89.0% 48.2%
3611472 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.68 55.0 4.67e-01 89.0% 72.4%
3587045 5065.1.1.2 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.67 49.0 3.50e-01 77.0% 27.7%
4295513 1075.3.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold 0.66 46.0 2.97e-01 72.0% 32.6%
4239731 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.66 47.0 4.47e-01 75.0% 75.0%
4951660 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.66 51.0 5.30e-01 82.0% 93.3%
3764064 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.64 51.0 5.44e-01 95.0% 100.0%
5067753 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.64 53.0 3.89e-01 94.0% 35.1%
4927073 101.1.2.136 alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.63 54.0 4.52e-01 95.0% 100.0%
3606961 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.62 53.0 4.74e-01 94.0% 69.0%
3476112 109.23.1.5 alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › EMC6 0.62 37.0 3.87e-01 73.0% 65.6%
3951929 191.1.1.10 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_6 0.62 54.0 4.95e-01 99.0% 77.8%
3590799 191.1.1.12 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_8 0.61 54.0 5.08e-01 100.0% 83.2%
5081836 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.61 46.0 3.78e-01 81.0% 97.4%
4942037 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.60 45.0 3.35e-01 79.0% 70.4%
3493153 2485.1.1.49 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_12 0.58 42.0 3.26e-01 76.0% 96.4%
3716237 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.57 45.0 3.62e-01 85.0% 42.5%
3786160 5001.1.1.64 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PalH 0.57 43.0 3.15e-01 80.0% 31.5%
3613320 605.3.1.0 alpha duplicates or obligate multimers › ROP-like › Nonstructural protein ns2, Nep, M1-binding domain › Nonstructural protein ns2, Nep, M1-binding domain 0.56 43.0 4.50e-01 99.0% 90.0%
3389526 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.55 44.0 4.49e-01 100.0% 89.0%
4044497 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.55 41.0 3.10e-01 80.0% 31.0%
3961309 191.1.1.48 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 0.55 47.0 4.45e-01 100.0% 78.4%
None 0.55 41.0 3.13e-01 81.0% 32.3%
5028154 3831.1.1.0 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.54 46.0 4.35e-01 97.0% 83.2%
5014639 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.53 40.0 4.07e-01 80.0% 92.0%
3181183 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 36.0 2.84e-01 70.0% 74.1%
3711247 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.52 44.0 3.14e-01 95.0% 83.4%
3961693 106.1.1.11 alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.52 45.0 3.91e-01 97.0% 93.1%
5051571 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 43.0 3.44e-01 98.0% 46.2%
3589119 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.52 45.0 3.45e-01 99.0% 69.4%
3839514 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.51 38.0 3.50e-01 78.0% 70.8%
4024699 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.51 45.0 4.03e-01 100.0% 83.4%
4013548 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 43.0 3.21e-01 97.0% 36.5%
3498509 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.51 40.0 3.69e-01 85.0% 80.0%
4032998 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.50 44.0 3.34e-01 100.0% 67.8%
D2 medium residues 307-349_368-496
PDB