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QGH71189.1

Arc-Vir

MK994522__QGH71189.1__X__00033

Identity

Accession:
MK994522 ↗
Protein ID:
QGH71189.1 ↗
Kingdom:
archaea

Quality

45.9 mean pLDDT

Taxonomy

TaxID: 2609788

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 67-193
PDB
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3n3dB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 43.0 3.26e-01 76.4% 57.5%
6fakA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.58 31.0 3.88e-01 84.3% 82.7%
3k5wA02 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.56 42.0 3.37e-01 78.7% 90.2%
7e4nA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 48.0 3.81e-01 96.9% 65.8%
1jkwA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 40.0 3.64e-01 76.4% 97.7%
3djbA01 1.10.472.50 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like 0.52 36.0 4.04e-01 70.9% 100.0%
1xaiA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.51 36.0 3.24e-01 73.2% 98.4%
4ag6A02 1.10.8.730 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 37.0 3.96e-01 75.6% 85.5%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4032310 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.93 78.0 7.27e-01 92.1% 72.7%
3981280 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.91 79.0 7.46e-01 98.4% 78.6%
3941716 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.83 68.0 6.76e-01 87.4% 83.1%
3980709 103.4.1.27 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › TMP_2 0.71 62.0 5.76e-01 94.5% 93.8%
3691904 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 48.0 5.12e-01 75.6% 99.1%
4986459 159.1.2.0 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related 0.63 53.0 4.99e-01 97.6% 75.5%
3231223 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.54 29.0 2.54e-01 74.0% 35.6%
3926309 1075.5.1.5 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 0.52 40.0 3.12e-01 81.9% 66.7%
5012225 611.6.1.1 alpha bundles › N-cbl like › PT26-6P helical domain › PT26-6P helical domain › PT26-6P_helical 0.52 36.0 3.50e-01 70.1% 86.9%
3582750 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.52 43.0 3.90e-01 89.8% 74.3%
4946802 7014.1.1.0 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain 0.52 31.0 3.30e-01 70.1% 67.3%
5045751 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.52 41.0 3.26e-01 84.3% 85.4%
4987542 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.51 41.0 3.62e-01 88.2% 88.0%
3971490 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.51 39.0 3.39e-01 81.1% 89.2%
3928180 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.51 42.0 3.60e-01 91.3% 74.4%
D2 medium residues 194-260
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10145.15 best PhageMin_Tail 53.1 5.50e-14 100.0% 31.3%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bvsF03 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.72 47.0 5.47e-01 76.1% 100.0%
2lyiA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.67 49.0 3.92e-01 82.1% 90.5%
2ahoB02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.66 48.0 4.40e-01 77.6% 76.9%
1v92A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.65 42.0 4.73e-01 92.5% 95.7%
3lcvB01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.65 49.0 5.23e-01 80.6% 100.0%
1yz6A02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.64 47.0 4.36e-01 79.1% 79.3%
1zv1A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.64 46.0 4.82e-01 92.5% 88.1%
2a19A02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.64 46.0 4.35e-01 79.1% 81.2%
1oaiA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.63 44.0 4.62e-01 98.5% 86.4%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.63 52.0 4.89e-01 97.0% 96.5%
1aorA02 1.10.569.10 Mainly Alpha › Orthogonal Bundle › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A; domain 2 › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2 0.63 54.0 4.01e-01 100.0% 42.5%
1nxuA01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.61 46.0 4.43e-01 83.6% 73.4%
4mbsA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 44.0 2.81e-01 76.1% 27.7%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 51.0 4.58e-01 95.5% 89.6%
2vixA02 1.10.150.630 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.58 43.0 3.93e-01 79.1% 77.5%
3fmyA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.58 41.0 4.17e-01 74.6% 87.9%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.58 47.0 4.44e-01 98.5% 95.5%
3uoeA01 1.10.1530.10 Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel 0.58 44.0 4.10e-01 85.1% 67.8%
7wvzA02 3.40.366.10 Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 0.57 49.0 3.17e-01 100.0% 31.2%
4gewA01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.55 40.0 3.90e-01 85.1% 68.8%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.55 41.0 3.57e-01 83.6% 76.6%
3bm1A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.55 39.0 2.91e-01 76.1% 88.1%
5v89A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.54 42.0 3.95e-01 89.6% 94.3%
6cnzF00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.54 46.0 3.59e-01 100.0% 62.0%
2n6yA00 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.53 37.0 3.55e-01 86.6% 62.5%
4irlB02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.53 38.0 3.46e-01 77.6% 77.4%
1ej5A00 3.90.810.10 Alpha Beta › Alpha-Beta Complex › SerineThreonine-protein kinase PAK-alpha; Chain A › CRIB domain 0.52 41.0 3.66e-01 91.0% 82.2%
1vb5A01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.51 37.0 3.32e-01 82.1% 55.3%
3oc2A01 3.90.1310.10 Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › Penicillin-binding protein 2a (Domain 2) 0.50 36.0 2.71e-01 74.6% 35.3%
3cymA03 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.50 40.0 3.80e-01 95.5% 85.2%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030882 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.98 95.0 6.33e-01 100.0% 31.9%
3245209 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.68 52.0 5.41e-01 92.5% 95.0%
4943373 102.3.1.1 alpha arrays › HhH/H2TH › eIF2alpha middle domain › eIF2alpha middle domain › EIF_2_alpha 0.67 48.0 4.49e-01 76.1% 81.2%
3229199 103.1.1.86 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › PF28543 0.66 50.0 5.10e-01 94.0% 87.7%
5029208 102.3.1.1 alpha arrays › HhH/H2TH › eIF2alpha middle domain › eIF2alpha middle domain › EIF_2_alpha 0.64 46.0 4.28e-01 76.1% 81.2%
3921797 5049.1.2.1 alpha complex topology › Ammonium transporter-related › Ammonium transporter-related › Urea transporter › UT 0.64 54.0 3.48e-01 98.5% 28.3%
3909658 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.64 48.0 4.00e-01 82.1% 73.6%
3631226 103.1.1.14 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › UBA_4 0.64 43.0 4.73e-01 91.0% 96.0%
4263712 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.63 50.0 4.54e-01 91.0% 84.2%
4933655 103.17.1.0 alpha arrays › RuvA-C › HMG-CoA reductase flap domain › HMG-CoA reductase flap domain 0.63 43.0 4.59e-01 89.6% 89.1%
4489811 103.17.1.0 alpha arrays › RuvA-C › HMG-CoA reductase flap domain › HMG-CoA reductase flap domain 0.62 43.0 4.63e-01 82.1% 100.0%
2808686 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.61 44.0 4.46e-01 77.6% 82.8%
2320936 103.17.1.0 alpha arrays › RuvA-C › HMG-CoA reductase flap domain › HMG-CoA reductase flap domain 0.61 41.0 4.40e-01 86.6% 95.9%
4442514 103.1.1.6 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C 0.61 42.0 4.63e-01 82.1% 98.0%
4932431 3050.1.1.7 alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal_L19e_C 0.60 45.0 3.84e-01 91.0% 47.1%
4653139 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.60 46.0 3.99e-01 85.1% 64.5%
4025457 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.60 51.0 4.77e-01 98.5% 84.7%
4976690 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.59 41.0 4.47e-01 77.6% 98.0%
3278934 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.59 43.0 4.47e-01 79.1% 96.7%
3575611 103.1.1.84 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › PF28540 0.59 41.0 4.09e-01 94.0% 71.4%
3690387 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.58 41.0 4.41e-01 97.0% 94.5%
4243068 3050.1.1.7 alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal_L19e_C 0.58 41.0 3.81e-01 77.6% 57.8%
3705785 3050.1.1.30 alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › TMEM254 0.57 44.0 4.01e-01 86.6% 77.9%
3226963 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.57 42.0 4.32e-01 80.6% 93.8%
4621718 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.54 46.0 3.78e-01 100.0% 69.6%
2996022 2007.1.19.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › Acyl_transf_1 0.53 44.0 3.67e-01 100.0% 75.4%
4941976 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.53 43.0 3.81e-01 98.5% 89.1%
3291254 2004.1.1.286 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TraG-D_C 0.52 40.0 2.39e-01 85.1% 23.2%
3712322 3050.1.1.0 alpha bundles › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain › Ribosomal protein L19 (L19e) C-terminal domain 0.51 39.0 3.19e-01 89.6% 92.0%
D3 medium residues 261-344
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k8pC01 1.20.58.1440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 3.96e-01 81.0% 89.5%
1uz3B00 1.10.1240.40 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › ENT domain 0.54 39.0 3.73e-01 75.0% 76.3%
4z7fB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.54 44.0 3.63e-01 92.9% 81.5%
2bk9A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 43.0 3.63e-01 89.3% 81.7%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.54 41.0 4.01e-01 84.5% 77.1%
3hlzA02 1.20.120.1090 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 43.0 3.81e-01 96.4% 88.4%
1z1nX01 3.90.10.10 Alpha Beta › Alpha-Beta Complex › Cytochrome C3 › Cytochrome C3 0.50 39.0 3.72e-01 83.3% 99.0%
4l80D00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.50 39.0 2.66e-01 86.9% 85.2%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5031480 283.1.1.1 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › Peptidase_M24 0.59 41.0 2.92e-01 72.6% 71.4%
3927989 4133.1.1.1 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › ENT 0.58 41.0 4.08e-01 75.0% 83.3%
3275293 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 44.0 3.11e-01 88.1% 26.0%
4935350 4018.1.1.2 a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P 0.56 39.0 3.16e-01 72.6% 67.3%
3515268 186.2.1.0 alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain 0.56 44.0 4.12e-01 86.9% 81.0%
3486395 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.56 38.0 3.74e-01 70.2% 96.7%
3965222 109.4.1.940 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Slam 0.55 34.0 2.88e-01 82.1% 35.3%
3642777 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.54 36.0 3.24e-01 75.0% 46.4%
3581996 101.1.1.10 alpha arrays › HTH › HTH › Three-helical HTH › ARID 0.54 38.0 3.54e-01 73.8% 85.7%
3626372 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.51 41.0 3.70e-01 92.9% 83.2%
4072100 5061.1.1.1 alpha complex topology › Preprotein translocase SecY subunit › Preprotein translocase SecY subunit › Preprotein translocase SecY subunit › SecY 0.51 42.0 2.89e-01 95.2% 79.1%
D4 medium residues 561-627
PDB
D5 medium residues 732-819
PDB
D6 medium residues 877-955
PDB