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QGH71217.1

Arc-Vir

MK994522__QGH71217.1__X__00061

Identity

Accession:
MK994522 ↗
Protein ID:
QGH71217.1 ↗
Kingdom:
archaea

Quality

44.6 mean pLDDT

Taxonomy

TaxID: 2609788

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-66
PDB
Domain cluster: representative
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.72 54.0 5.35e-01 80.3% 80.9%
2xtuA00 1.20.1540.10 Mainly Alpha › Up-down Bundle › Rhomboid-like fold › Rhomboid-like 0.72 63.0 4.61e-01 100.0% 37.6%
2hpsA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.71 53.0 3.80e-01 80.3% 50.0%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.70 58.0 5.29e-01 93.9% 83.5%
3pm6A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.69 59.0 3.86e-01 95.5% 86.4%
2vm6A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.68 52.0 4.03e-01 81.8% 91.0%
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.67 48.0 3.13e-01 77.3% 17.1%
5u4nA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.67 57.0 3.66e-01 98.5% 84.6%
3oqvA00 3.40.50.11710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase 0.66 51.0 3.63e-01 86.4% 41.2%
3nc3B00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.65 51.0 3.18e-01 86.4% 29.6%
2k3nA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.65 55.0 4.27e-01 100.0% 70.0%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.64 45.0 3.55e-01 75.8% 45.8%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.64 43.0 3.49e-01 71.2% 69.2%
2ivxB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.64 49.0 4.08e-01 92.4% 47.8%
3dkaB01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.63 57.0 4.49e-01 100.0% 94.1%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 45.0 3.93e-01 75.8% 49.0%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.63 53.0 4.94e-01 98.5% 75.3%
1z21A00 1.10.10.1000 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Type III secretion system virulence factor YopR, core domain 0.62 39.0 3.55e-01 80.3% 43.8%
1vluA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.62 47.0 3.15e-01 80.3% 66.1%
3hx3A01 1.10.8.20 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p 0.62 48.0 4.78e-01 97.0% 82.1%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 46.0 3.87e-01 78.8% 74.8%
3c1dB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 38.0 3.92e-01 72.7% 66.1%
7e84A02 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.61 44.0 3.46e-01 75.8% 78.4%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.60 45.0 3.35e-01 83.3% 30.4%
7emyA03 3.30.559.30 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Nonribosomal peptide synthetase, condensation domain 0.60 49.0 3.32e-01 95.5% 75.3%
1nv8B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.60 50.0 4.95e-01 100.0% 88.7%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.59 44.0 3.44e-01 81.8% 86.9%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 48.0 4.15e-01 90.9% 85.8%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 51.0 3.88e-01 97.0% 77.8%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.59 44.0 4.06e-01 81.8% 77.0%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 41.0 3.43e-01 75.8% 90.5%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.58 44.0 3.95e-01 78.8% 70.3%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.58 50.0 4.05e-01 100.0% 65.9%
2ds2D01 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.57 40.0 4.28e-01 80.3% 87.7%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 46.0 3.68e-01 93.9% 79.3%
4huqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 3.06e-01 93.9% 24.3%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.56 48.0 4.53e-01 97.0% 86.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 47.0 3.63e-01 93.9% 92.1%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 42.0 3.67e-01 86.4% 84.8%
2lrmA00 1.10.890.30 Mainly Alpha › Orthogonal Bundle › 10k-s Protein, Hypothetical Protein A; Chain A › YmgD protein 0.56 47.0 4.42e-01 97.0% 92.9%
4j0eA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 44.0 3.19e-01 89.4% 34.7%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.53 39.0 3.63e-01 78.8% 64.7%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.53 39.0 3.68e-01 78.8% 66.2%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.53 38.0 3.53e-01 74.2% 62.4%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.52 47.0 3.95e-01 100.0% 87.3%
2c0gA02 1.20.1150.12 Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain 0.52 39.0 3.43e-01 83.3% 88.7%
2j1dG01 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.52 41.0 2.57e-01 86.4% 50.0%
2cdqA02 1.20.120.1320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain 0.52 44.0 3.98e-01 100.0% 71.1%
1iurA01 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.51 36.0 3.68e-01 77.3% 79.4%
3qxyA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.51 43.0 3.26e-01 97.0% 55.1%
2yhaA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.50 41.0 2.92e-01 93.9% 82.5%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3726362 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.81 63.0 5.67e-01 83.3% 61.1%
3591291 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.78 59.0 4.12e-01 81.8% 26.6%
4017306 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.76 56.0 5.28e-01 86.4% 65.0%
4032972 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.76 67.0 4.83e-01 100.0% 35.8%
3190824 166.1.1.0 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C 0.75 52.0 5.01e-01 74.2% 64.0%
3284139 5081.1.1.3 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid_2 0.74 65.0 4.61e-01 98.5% 38.5%
3436965 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.72 54.0 4.83e-01 81.8% 62.1%
3438464 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.72 49.0 5.33e-01 77.3% 94.0%
3398929 5041.1.1.32 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 0.70 53.0 4.80e-01 81.8% 61.1%
3588334 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 54.0 4.40e-01 90.9% 44.8%
3838265 152.1.2.1 alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 0.67 57.0 5.69e-01 93.9% 92.8%
4023307 183.1.1.0 alpha duplicates or obligate multimers › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain › Iron-dependent repressor protein, dimerization domain 0.67 46.0 4.41e-01 71.2% 69.3%
4059386 152.1.2.1 alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 0.67 57.0 5.79e-01 93.9% 96.9%
4224947 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.66 55.0 4.73e-01 100.0% 58.1%
3261624 3470.1.1.0 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain 0.66 47.0 5.23e-01 80.3% 100.0%
3961186 103.9.1.0 alpha arrays › RuvA-C › RanGAP2 N-terminal domain › RanGAP2 N-terminal domain 0.66 54.0 4.78e-01 93.9% 94.0%
3792061 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 45.0 3.88e-01 77.3% 45.6%
4619372 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.65 54.0 5.31e-01 93.9% 86.3%
3929410 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.65 47.0 2.92e-01 78.8% 53.3%
3218921 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 43.0 3.69e-01 75.8% 42.2%
5012158 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.64 48.0 4.22e-01 78.8% 55.8%
4014527 532.2.1.0 alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains 0.64 46.0 4.18e-01 78.8% 58.9%
4249597 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.64 46.0 4.03e-01 78.8% 54.3%
4020688 610.1.1.0 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like 0.63 43.0 3.81e-01 77.3% 47.0%
4991390 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.63 46.0 4.16e-01 81.8% 54.7%
3591103 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.63 46.0 3.10e-01 77.3% 28.4%
4941740 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.63 51.0 3.10e-01 92.4% 65.2%
3262801 3788.1.1.0 alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) 0.62 52.0 4.38e-01 100.0% 52.8%
4001770 4044.1.1.12 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › RH_dom 0.61 56.0 4.91e-01 100.0% 81.1%
3392986 632.1.1.19 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › RH_dom 0.60 55.0 4.74e-01 100.0% 77.0%
3801730 1128.1.1.12 alpha bundles › LYR protein › LYR protein › LYR protein › RH_dom 0.59 53.0 4.62e-01 100.0% 78.0%
5042372 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.59 45.0 3.94e-01 83.3% 100.0%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 43.0 3.95e-01 77.3% 92.9%
4367522 601.14.1.12 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Rab3-GAP_cat_C 0.59 53.0 3.96e-01 100.0% 45.0%
3389329 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.59 49.0 3.22e-01 97.0% 70.6%
3286103 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.58 52.0 4.86e-01 98.5% 91.3%
4939653 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 43.0 3.13e-01 84.8% 27.1%
396152 4009.1.1.3 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › KTI12 0.57 42.0 4.08e-01 81.8% 69.3%
5023625 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.57 43.0 3.79e-01 81.8% 73.0%
3589614 601.1.2.99 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar 0.57 49.0 4.07e-01 100.0% 74.0%
3179544 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 44.0 3.14e-01 78.8% 27.9%
3183751 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.57 47.0 2.99e-01 92.4% 72.8%
3940797 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.57 40.0 3.76e-01 78.8% 59.5%
4250716 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.57 45.0 4.08e-01 89.4% 67.4%
3616218 633.24.1.6 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › PF26202 0.56 43.0 3.18e-01 80.3% 36.4%
3207847 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.56 49.0 4.52e-01 100.0% 77.6%
2823637 5000.3.1.1 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.54 40.0 3.21e-01 83.3% 92.7%
4026128 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.54 45.0 3.56e-01 97.0% 92.0%
143026 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.53 41.0 2.88e-01 83.3% 30.8%
4106111 4009.1.1.11 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › NA37 0.52 44.0 3.97e-01 97.0% 70.0%
4074186 4953.1.1.32 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › NA37 0.52 44.0 3.97e-01 97.0% 70.0%
D2 high residues 77-164
PDB
D3 high residues 267-360
PDB